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# Cancerworld Magazine

## Sitemaps

- [XML Sitemap](https://cancerworld.net/sitemap.xml): Contains all public & indexable URLs for this website.

## Posts

- [Multi-cancer early detection blood test speeds up cancer diagnosis](https://cancerworld.net/multi-cancer-detection-blood-test/) - A multi-cancer early detection test showed a positive predictive accuracy of 75% and negative predictive accuracy of 98% in a population referred for diagnostic follow-up after presenting to primary care with symptoms of cancer. The SYMPLIFY study, abstract 1501, presented in an oral abstract session at the ASCO 2023 Annual Meeting, also found that the
- [Harald zur Hausen: the virologist who opened a pathway to eliminating cervical cancer](https://cancerworld.net/harald-zur-hausen/) - Harald zur Hausen, virologist and Nobel laureate, passed away on May 28th. His great discovery, that cervical cancer is caused by the human papilloma virus (HPV), opened the way for significantly reducing the risk of developing this disease – still the fourth biggest cancer killer of women globally – among upcoming generations the world over.
- [Cracking RAS: It took over 30 years to hit this ubiquitous oncogene – was it worth the wait?](https://cancerworld.net/cracking-ras-oncogene/) - RAS oncogenes and their proteins have central roles in almost all cancers, including leukaemias, multiple myelomas, skin cancers and many solid tumours, making the RAS protein family an ideal cancer target. But efforts to develop clinically efficacious drugs to target RAS, starting in the early 1990s, met with unforeseen hurdles and disappointing clinical progress. The
- [Stopping immunotherapy after two years does not affect NSCLC survival](https://cancerworld.net/stopping-immunotherapy-survival/) - No overall survival difference was found between patients with non-small cell lung cancer who stopped immune checkpoint inhibitors at two years and those continuing treatment indefinitely. The study, abstract 9101, presented at the ASCO 2023 Annual Meeting, held June 2–6, and published simultaneously online in JAMA Oncology, also showed that, after progression, patients treated with
- [Adding a CDK4/6 inhibitor to endocrine therapy improves outcomes in HR+  HER2– early-stage breast cancer](https://cancerworld.net/adding-a-cdk4-6-inhibitor-outcomes-breast-cancer/) - Adding the CDK4/6 inhibitor ribociclib to standard-of-care adjuvant endocrine therapy for treatment of hormone receptor-positive HER2-negative early-stage breast cancer reduced risk of recurrence by 25%. The phase III NATALEE study, abstract LBA500, presented at the ASCO 2023 Annual Meeting, held June 2–6, showed for the first time that ribociclib combined with endocrine therapy improved outcomes
- [Mariam Kukhalashvili: solving Georgia’s cancer problems](https://cancerworld.net/mariam-kukhalashvili-solving-georgias-cancer-problems/) - Clinical oncologist Mariam Kukhalashvili was only 32 when, in 2021, she was appointed head of the outpatient department at the Western Georgia Oncology Centre in Kutaisi – one of the largest and most up-to-date cancer services outside the capital Tbilisi. It was a big responsibility for someone her age, but it was also a sign
- [CancerWorld #118 (August 2026)](https://cancerworld.net/cancerworld-118-august-2026/) - CancerWorld August 2026 explores how patient voices, advocacy, and lived experience are reshaping cancer care alongside scientific discovery.
- [Could GLP-1 Drugs Slow Cancer Spread? New Study Offers Encouraging Clues](https://cancerworld.net/could-glp-1-drugs-slow-cancer-spread-new-study-offers-encouraging-clues/) - A new ASCO 2026 study suggests GLP-1 drugs may reduce metastatic progression in several cancers, but randomized trials are needed to confirm.
- [Behind Every Drug There Is a Story: Brian Druker, Imatinib, and the Human Journey Behind a Revolution in Cancer Care](https://cancerworld.net/behind-every-drug-there-is-a-story-brian-druker-imatinib-and-the-human-journey-behind-a-revolution-in-cancer-care/) - Brian Druker reflects on imatinib, CML, curiosity, setbacks, and the patients who helped shape one of oncology’s most transformative breakthroughs.
- [Beyond Treatment: Why Psycho-Oncological Education Matters for Patients and Their Caregivers](https://cancerworld.net/beyond-treatment-why-psycho-oncological-education-matters-for-patients-and-their-caregivers/) - Psycho-oncological education empowers cancer patients and caregivers with knowledge, coping skills, and emotional support throughout treatment.
- [Finding a Voice Beyond Cancer: How Karen Nakawala transformed a cervical cancer diagnosis into a movement for survivor leadership and better cancer care](https://cancerworld.net/finding-a-voice-beyond-cancer-how-karen-nakawala-transformed-a-cervical-cancer-diagnosis-into-a-movement-for-survivor-leadership-and-better-cancer-care/) - After surviving cervical cancer, Karen Nakawala founded Teal Sisters, transforming her diagnosis into a movement for survivor leadership and better care.
- [Global Inequalities in Access to Radiation Treatment](https://cancerworld.net/global-inequalities-in-access-to-radiation-treatment/) - Millions of cancer patients still lack access to radiotherapy. Rahul Barve explores the global treatment gap, its causes, and solutions for equity.Millions of cancer patients still lack access to radiotherapy. Rahul Barve explores the global treatment gap, its causes, and solutions for equity.
- [When RAS Becomes Treatable: Eileen O’Reilly on daraxonrasib in Pancreatic Cancer](https://cancerworld.net/when-ras-becomes-treatable-eileen-oreilly-on-daraxonrasib-in-pancreatic-cancer/) - Daraxonrasib is reshaping pancreatic cancer care. Dr Eileen O’Reilly explains the RASolute 302 trial, targeted therapy, and what comes next.
- [From Treating Children to Shaping Global Cancer Policy: Dr Tezer Kutluk on Leadership, Equity, and the Future of Oncology](https://cancerworld.net/from-treating-children-to-shaping-global-cancer-policy-dr-tezer-kutluk-on-leadership-equity-and-the-future-of-oncology/) - Dr. Tezer Kutluk reflects on four decades in oncology, global leadership, and why equity—not innovation alone—will define the future of cancer care worldwide.
- [Daraxonrasib: A Turning Point for Pancreatic Cancer](https://cancerworld.net/daraxonrasib-a-turning-point-for-pancreatic-cancer/) - How daraxonrasib doubled survival in pancreatic cancer and why the RASolute 302 trial may redefine the future of RAS-targeted therapy.
- [Doctor of Hope](https://cancerworld.net/doctor-of-hope/) - Discover how Professor Nagi El Saghir transformed cancer care in the Middle East through leadership, education, research, and hope.
- [Larry Leksell: The story of Elekta](https://cancerworld.net/larry-leksell-the-story-of-elekta/) - From a family startup to transforming radiation oncology, Larry Leksell reflects on Elekta, Gamma Knife, innovation, resilience, and the future of cancer care.
- [CancerWorld #117 (July 2026)](https://cancerworld.net/cancerworld-117-july-2026/) - CancerWorld July 2026 explores how leadership, innovation, and equitable access turn scientific breakthroughs into better cancer care worldwide.
- [The Ovation and the Asterisk](https://cancerworld.net/the-ovation-and-the-asterisk/) - ASCO 2026 plenary showcased five major cancer breakthroughs—and the challenges that still stand between scientific progress and patient access.
- [Between Theory and Bedside: What Early Palliative Care in Singapore Reveals About Cancer, Care, and the Limits of Knowledge](https://cancerworld.net/between-theory-and-bedside-what-early-palliative-care-in-singapore-reveals-about-cancer-care-and-the-limits-of-knowledge/) - Explore how Singapore's ENABLE-SG study shows early palliative care improves cancer support by combining evidence, empathy and patient-centered care.
- [The Right to Be Forgotten: Why Voluntary Measures are Not Enough for Cancer Survivors ](https://cancerworld.net/the-right-to-be-forgotten-why-voluntary-measures-are-not-enough-for-cancer-survivors/) - Cancer Patients Europe urges binding EU legislation on the Right to Be Forgotten to end financial discrimination against cancer survivors.
- [This is WHO](https://cancerworld.net/this-is-who/) - Editorial by Gevorg Tamamyan highlights Dr. André Ilbawi and the people behind WHO, showing global health leadership, sacrifice, and human impact.
- [Building Beyond the Bedside: Dr Mohamed Emam Sobeih’s Vision for the Future of Oncology](https://cancerworld.net/building-beyond-the-bedside-dr-mohamed-emam-sobeihs-vision-for-the-future-of-oncology/) - Discover how Dr. Mohamed Emam Sobeih is advancing oncology through leadership, education, mentorship, and patient-centered cancer care in Egypt.
- [European Cancer Nursing Day 2026: Supporting Life Beyond Cancer](https://cancerworld.net/european-cancer-nursing-day-2026-supporting-life-beyond-cancer/) - Discover highlights from European Cancer Nursing Day 2026 as EONS celebrates oncology nurses advancing survivorship, innovation, research and compassionate care.
- [Oncologists Urged to Have Open Discussion about CAM Use with Patients](https://cancerworld.net/oncologists-urged-to-have-open-discussion-about-cam-use-with-patients/) - Study of 2 million breast cancer patients links CAM use to higher mortality, highlighting the need for open patient-clinician discussions on treatment.
- [The Scientists Who Turned Cancer Prevention into a Vaccine: Dr Douglas Lowy and Dr John Schiller](https://cancerworld.net/the-scientists-who-turned-cancer-prevention-into-a-vaccine-dr-douglas-lowy-and-dr-john-schiller/) - Discover how Douglas Lowy and John Schiller pioneered HPV vaccines, transforming cancer prevention and earning the 2026 Pezcoller–AACR Award worldwide today.!!!
- [Cancer is Universal. Meaning is Not!](https://cancerworld.net/cancer-is-universal-meaning-is-not/) - Cancer is universal, but its meaning varies across cultures. Explore how beliefs, stigma, and empathy shape cancer communication and patient care.
- [No Woman Left Behind: Dr Miriam Mutebi and the Quest for Equitable Cancer Care in Africa](https://cancerworld.net/no-woman-left-behind-dr-miriam-mutebi-and-the-quest-for-equitable-cancer-care-in-africa/) - Cancer care is about more than medicine. Dr. Miriam Mutebi explores leadership, equity, and why access remains oncology’s greatest challenge.
- [CancerWorld #116 (June 2026)](https://cancerworld.net/cancerworld-116-june-2026/) - CancerWorld #116 explores the gap between discovery and delivery in cancer care, examining equity, global health, survivorship, and real-world impact.
- [Rewriting RAS: A New Targeted Option on the Horizon for Pancreatic Cancer](https://cancerworld.net/rewriting-ras-a-new-targeted-option-on-the-horizon-for-pancreatic-cancer/) - Daraxonrasib and RAS inhibition are showing promise in metastatic pancreatic cancer. Could targeted therapy finally challenge chemotherapy standards?
- [Immunotherapy's Hidden Burden: Rethinking Toxicity in the Era of Breakthroughs](https://cancerworld.net/immunotherapys-hidden-burden-rethinking-toxicity-in-the-era-of-breakthroughs/) - Immunotherapy is transforming cancer care, but immune-related toxicities demand better detection, supportive care and multidisciplinary action worldwide today.
- [After the Bell: Rethinking Cancer Care Beyond Treatment](https://cancerworld.net/after-the-bell-rethinking-cancer-care-beyond-treatment/) - Discover why cancer care must extend beyond treatment, addressing survivorship, mental health, identity, and quality of life after cancer therapy. for all. now!
- [From Silence to Presence: Dr Christian Ntizimira on Reimagining End-of-Life Care](https://cancerworld.net/from-silence-to-presence-dr-christian-ntizimira-on-reimagining-end-of-life-care/) - Dr. Christian Ntizimira explores dignity, Ubuntu, and palliative care, redefining end-of-life support through presence, compassion, and community across Africa
- [A Survivor's Perspective: San Diego's Rise as a National Cancer Research Hub](https://cancerworld.net/a-survivors-perspective-san-diegos-rise-as-a-national-cancer-research-hub/) - Survivor perspective on San Diego’s rise as a cancer research hub,showing how early detection, policy, philanthropy, and collaboration drive progress in oncology
- [A Matter of Timing: Radiotherapy Efficacy Linked to Circadian Regulation ](https://cancerworld.net/a-matter-of-timing-radiotherapy-efficacy-linked-to-circadian-regulation/) - Study shows radiotherapy timing impacts breast and prostate cancer outcomes via circadian CRY1 regulation, improving effectiveness in afternoon and evening.
- [Rewriting the Surgical Narrative: Dr Lazaros Papadopoulos On Breast Cancer Care, Mentorship, and the Meaning of Small Changes](https://cancerworld.net/rewriting-the-surgical-narrative-dr-lazaros-papadopoulos-on-breast-cancer-care-mentorship-and-the-meaning-of-small-changes/) - Dr Lazaros Papadopoulos shares insights on breast cancer care, surgical oncology, mentorship, innovation, and patient-centred treatment. across Europe now today.
- [“Between the Checkpoints of Life, Take the Immunobuddies with You” —Professor Ricky Dylan Frazer](https://cancerworld.net/between-the-checkpoints-of-life-take-the-immunobuddies-with-you-professor-ricky-dylan-frazer/) - Professor Ricky Dylan Frazer discusses immunotherapy, melanoma care, oncology leadership, and the growing impact of the Immunobuddies network across the UK hub.
- [Charles Balch Treated Thousands of Patients. He Says That's Not His Greatest Work. ](https://cancerworld.net/charles-balch-treated-thousands-of-patients-he-says-thats-not-his-greatest-work/) - A powerful profile of Charles Balch, exploring his impact on oncology, cancer prevention, mentorship, and global cancer care innovation.
- [Mission 2027: Mission is Possible](https://cancerworld.net/mission-2027-mission-is-possible/) - Rwanda aims to eliminate cervical cancer by 2027. In CancerWorld interview, Dr Sabin Nsanzimana discusses health system rebuilding, leadership, Mission 2027.
- [CancerWorld #115 (May 2026)](https://cancerworld.net/cancerworld-115-may-2026/) - CancerWorld #115 explores oncology progress vs delivery, Rwanda’s cervical cancer Mission 2027, immunotherapy, precision oncology, survivorship, global health.WHO
- [Cancer Vaccines: From Missed Promise to Second Chance](https://cancerworld.net/cancer-vaccines-from-missed-promise-to-second-chance/) - Cancer vaccines and the future of immunotherapy: from early setbacks to mRNA neoantigen breakthroughs and combination therapy with checkpoint inhibitors.
- [Psycho-Oncology at a Crossroads: From Global Recognition to Real-World Impact](https://cancerworld.net/psycho-oncology-at-a-crossroads-from-global-recognition-to-real-world-impact/) - World Psycho-Oncology Day highlights the urgent need for mental health, emotional support and equitable psychosocial care in cancer treatment worldwide for all.
- [CancerWorld | The Max Foundation – Special Issue 2026](https://cancerworld.net/cancerworld-the-max-foundation-special-issue-2026/) - Explore 25 years of TKI-driven progress in CML and the global effort to expand access to lifesaving leukemia treatment and patient care worldwide for everyone!
- [Reflections on Patient-Centred Decision-Making in Oncology](https://cancerworld.net/reflections-on-patient-centred-decision-making-in-oncology/) - Reflections on patient-centred oncology care, highlighting ethics, communication, and autonomy in end-of-life decisions within complex cancer care settings.
- [Pancreatic Cancer Europe at 10: Turning the Tide on Europe’s Deadliest Common Cancer](https://cancerworld.net/pancreatic-cancer-europe-at-10-turning-the-tide-on-europes-deadliest-common-cancer/) - Pancreatic Cancer Europe marks 10 years driving EU action on early detection, research and care to improve survival and reduce cancer inequality across Europe.
- [From “No Chance” to “All Bloody Clear”: John Walker Pattison’s 50-Year Journey and the Challenge of Cancer Survivorship](https://cancerworld.net/from-no-chance-to-all-bloody-clear-john-walker-pattisons-50-year-journey-and-the-challenge-of-cancer-survivorship/) - A powerful cancer survivorship story of survival, late effects, and resilience, showing life beyond treatment and the reality of “all clear.”
- [“Medicine is Deeply Relational: The Human Heart of Oncology in the Age of AI”](https://cancerworld.net/medicine-is-deeply-relational-the-human-heart-of-oncology-in-the-age-of-ai/) - Oncology in the age of AI: why human connection, empathy, and integrating research with patient care remain essential to delivering better cancer outcomes.
- [Nutrition in Cancer Care: Closing the Gap Between Awareness and Action](https://cancerworld.net/nutrition-in-cancer-care-closing-the-gap-between-awareness-and-action/) - Cancer nutrition is essential yet underused in Europe. Patients face care gaps despite evidence. Urgent policy action needed to integrate nutrition in oncology.
- [ Isabel Mestres: The Doer](https://cancerworld.net/isabel-mestres-the-doer/) - Isabel Mestres leads City Cancer Challenge, closing the gap between global health plans and real cancer care through practical system transformation.
- [OncoCorridor](https://cancerworld.net/oncocorridor/) - OncoCorridor connects cancer patients in war zones to global treatment centers, ensuring access to life-saving care when conflict blocks cure worldwide today!
- [CancerWorld #114 (April 2026)](https://cancerworld.net/cancerworld-114-april-2026/) - Explore CancerWorld April 2026: oncology in conflict, innovation, ethics, AI patient care, vaccines, and survivorship shaping the future of global cancer care.
- [Lived Experience of People Affected by Cancer](https://cancerworld.net/lived-experience-of-people-affected-by-cancer/) - Exploring the lived experience of cancer, this article examines fear, hope, resilience, and empathy in psycho-oncology and holistic patient care.
- [Translating Global Excellence into Local Impact: Dr Fatjona Kraja and the Challenge of  Transforming Radiation Oncology in Albania](https://cancerworld.net/translating-global-excellence-into-local-impact-dr-fatjona-kraja-and-the-challenge-of-transforming-radiation-oncology-in-albania/) - Dr. Fatjona Kraja transforms oncology expertise into impact in Albania, advancing patient-centered radiation care, quality systems, and medical education today.
- [“Hope is Constant “: From Isolation and Fear to Connection, Purpose, and Global Impact](https://cancerworld.net/hope-is-constant-from-isolation-and-fear-to-connection-purpose-and-global-impact/) - From a stage 4 melanoma diagnosis to a global story of hope, resilience, and connection—discover how shared stories transform cancer journeys worldwide today.
- [Michael Gnant at the Crossroads of Oncology: Precision, Restraint, and the Courage to Challenge Orthodoxy](https://cancerworld.net/michael-gnant-at-the-crossroads-of-oncology-precision-restraint-and-the-courage-to-challenge-orthodoxy/) - Explore Dr. Michael Gnant's oncology journey, advancing precision medicine, clinical trials, de-escalation, ctDNA, and patient-centered cancer care worldwide.
- [From Dalian to Houston and Back to Yemen: Bridging the Global Oncology Divide](https://cancerworld.net/from-dalian-to-houston-and-back-to-yemen-bridging-the-global-oncology-divide/) - Dr. Mohammed Safi shares his journey bridging the global oncology divide, highlighting cancer care challenges and innovations from Yemen to Houston.
- [The Day Immunotherapy Went Off-Patent](https://cancerworld.net/the-day-immunotherapy-went-off-patent/) - Nivolumab goes off-patent, opening access to immunotherapy worldwide. Biosimilars may lower costs and expand cancer treatment for patients globally.
- [Leading with Listening: Why Isabel Rubio Believes Europe’s Cancer Future Depends on Trust, Equity, and Political Courage](https://cancerworld.net/leading-with-listening-why-isabel-rubio-believes-europes-cancer-future-depends-on-trust-equity-and-political-courage/) - Dr. Isabel Rubio leads Europe’s cancer care with trust, equity, and policy innovation, tackling inequalities and shaping patient-centered oncology leadership.
- [Bente Mikkelsen: “Success is Something We Build Together”](https://cancerworld.net/bente-mikkelsen-success-is-something-we-build-together/) - Bente Mikkelsen drives global pediatric cancer care, health equity, and innovation, transforming healthcare systems from Norway to WHO to St. Jude Children’s.
- [Karen Knudsen: The Scientist Who Refused to Move Slowly](https://cancerworld.net/karen-knudsen-the-scientist-who-refused-to-move-slowly/) - Karen Knudsen, CEO of Parker Institute, drives ambitious cancer research, turning discoveries into cures and advancing patient-centered immunotherapy.
- [CancerWorld #113 (March 2026)](https://cancerworld.net/cancerworld-113-march-2026/) - CancerWorld March 2026 explores oncology breakthroughs, leadership, policy, and patient-centred care, turning scientific discovery into real-world impact.
- [“United by Unique” – Does it Really Make a Difference, or is it Just a Cliché?](https://cancerworld.net/united-by-unique-does-it-really-make-a-difference-or-is-it-just-a-cliche/) - An insightful article exploring the “United by Unique” theme, emphasizing patient-centered cancer care, psychosocial support, mental well-being, dignity, compassion, and holistic healing.
- [Making Sense of a Decade of Progress in Advanced Breast Cancer: ABC8, Lisbon 2025](https://cancerworld.net/making-sense-of-a-decade-of-progress-in-advanced-breast-cancer-abc8-lisbon-2025/) - Explore a decade of breakthroughs in advanced breast cancer, survival gains, patient advocacy, and the fight for equitable access to care worldwide.
- [Europe’s National Cancer Mission Hubs: From a Vision to Sustainable Infrastructures](https://cancerworld.net/europes-national-cancer-mission-hubs-from-a-vision-to-sustainable-infrastructures/) - Europe’s cancer policy enters its implementation era as National Cancer Mission Hubs turn ambition into sustainable systems and real patient impact.
- [Rethinking Immunotherapy for Pancreatic Cancer: A Universal Approach](https://cancerworld.net/rethinking-immunotherapy-for-pancreatic-cancer-a-universal-approach/) - Breakthrough CAR-NKT cell therapy offers a powerful, off-the-shelf immunotherapy approach for pancreatic cancer and other solid tumors.
- [The European Semester on Health: Why CPE is Calling for Action on Cancer Inequalities ](https://cancerworld.net/the-european-semester-on-health-why-cpe-is-calling-for-action-on-cancer-inequalities/) - Cancer Patients Europe urges EU action to tackle cancer inequalities, ensuring equal access, care, and outcomes for all patients across Europe.
- [“A Novel Path With Risks”](https://cancerworld.net/a-novel-path-with-risks/) - How Professor Arjun K. Ghosh built cardio-oncology from scratch, transforming cancer care by protecting heart health without stopping life-saving treatment.
- [Hosams Abu Meri: From Mountain Village in Lebanon to the Heart of Latvian Health Reform](https://cancerworld.net/hosams-abu-meri-from-mountain-village-in-lebanon-to-the-heart-of-latvian-health-reform/) - Latvia’s Health Minister and practicing gastroenterologist Hosams Abu Meri on cancer policy, screening, drug access, and building a resilient health system.
- [Cary Adams: A Career of Change, Changing Careers.](https://cancerworld.net/cary-adams-a-career-of-change-changing-careers/) - Cary Adams’ journey from banking to leading UICC shows how vision, leadership, and courage can transform global cancer control.
- [Hesham Elghazaly: Pharaoh of Oncology](https://cancerworld.net/hesham-elghazaly-pharaoh-of-oncology/) - Discover how Hesham Elghazaly transformed oncology in Egypt, cutting breast cancer mortality and building a global blueprint for cancer care.
- [“The Path Forward is Clear”](https://cancerworld.net/the-path-forward-is-clear/) - Discover how the EU’s Beating Cancer Plan drives prevention, screening, innovation, and equal access to care across Europe.
- [CancerWorld #112 (February 2026)](https://cancerworld.net/cancerworld-112-february-2026/) - Leadership, policy, and innovation shaping the future of cancer care—global insights, breakthrough science, and human stories driving real change in oncology.
- [Sustainability, the Architecture of Equitable Cancer Innovation ](https://cancerworld.net/sustainability-the-architecture-of-equitable-cancer-innovation/) - Exploring sustainable, equitable cancer innovation: how value-based care, dose optimisation, and policy can expand global access to therapies.
- [Gentle with People. Precise with Cancer.](https://cancerworld.net/gentle-with-people-precise-with-cancer/) - Andrea Filippi, Milan radiation oncology leader, redefines cancer care with precise radiotherapy, AI, and inclusive trials for fragile patients.
- [Judy Habib: Named for Hope ](https://cancerworld.net/judy-habib-named-for-hope/) - Judy Habib leads St. Jude, transforming pediatric cancer care through legacy, philanthropy, and nonprofit leadership—finding cures, saving children.
- [CancerWorld #111 (January 2026)](https://cancerworld.net/cancerworld-111-january-2026/) - CancerWorld #111 examines leadership, equity, and values shaping cancer care, through powerful stories where policy, innovation and humanity meet.
- [CancerWorld | My Child Matters - Special Issue 2025](https://cancerworld.net/cancerworld-my-child-matters-special-issue-2025/) - Celebrating 20 years of My Child Matters and its global impact on childhood cancer care, from early diagnosis to family-centered support in LMICs.
- [Robert A. Weinberg: The Architect of Modern Cancer Biology](https://cancerworld.net/robert-a-weinberg-the-architect-of-modern-cancer-biology/) - Discover how Robert A. Weinberg transformed cancer research—from oncogenes to the Hallmarks of Cancer—and shaped a generation of molecular oncologists.
- [“I Live for Two”: Isabel’s Daydreaming World Between Grief and Light](https://cancerworld.net/i-live-for-two-isabels-daydreaming-world-between-grief-and-light/) - A former model turns grief into art, creating a dreamlike world of horses, color, and hope after losing her brother and finding freedom through painting.
- [Common Sense Oncology: Putting Patients Back at the Center in the Era of Cancer Innovation](https://cancerworld.net/common-sense-oncology-putting-patients-back-at-the-center-in-the-era-of-cancer-innovation/) - Common Sense Oncology calls for re-centering cancer innovation on outcomes that matter to patients—survival, quality of life, equity, and meaningful benefit—over surrogate endpoints.
- [Surviving the Tumor, Living with the Impact](https://cancerworld.net/surviving-the-tumor-living-with-the-impact/) - Brain tumor survivorship begins at diagnosis. This article examines cognitive, neurological and psychosocial impacts, care gaps, and innovation in care today
- [Beyond the Checkpoint: What Comes After PD-1?](https://cancerworld.net/beyond-the-checkpoint-what-comes-after-pd-1/) - Beyond PD-1 inhibitors: exploring the next era of cancer immunotherapy, from mRNA vaccines and smart cytokines to T-cell engagers and cell therapy.
- [Researcher’s Perspective on the Time Toxicity of Cancer Care](https://cancerworld.net/researchers-perspective-on-the-time-toxicity-of-cancer-care/) - Time toxicity in cancer care reveals the hidden burden of treatment. This article explores how measuring “contact days” can improve decision-making in oncology.
- [From Health Literacy to Health-Rights Literacy: Bringing the How into Cancer-Screening Awareness](https://cancerworld.net/from-health-literacy-to-health-rights-literacy-bringing-the-how-into-cancer-screening-awareness/) - From health literacy to health-rights literacy: why cancer-screening awareness must include clear guidance on access, navigation, and equity across Europe.
- [Cancer Treatment at Home: Inside Kenya’s Early Experience](https://cancerworld.net/cancer-treatment-at-home-inside-kenyas-early-experience/) - Home-based cancer treatment is becoming safer and more patient-centred, with new therapies offering comfort and reduced hospital visits.
- [Minister Robert Troy: “Because I Wanted to Be a Voice for Others” Leading Ireland’s Right to Be Forgotten Reform](https://cancerworld.net/minister-robert-troy-because-i-wanted-to-be-a-voice-for-others-leading-irelands-right-to-be-forgotten-reform/) - Minister Robert Troy reveals the human story behind Ireland’s Right to Be Forgotten reform, driven by empathy, loss, and fairness.
- [The Person Behind the Legend: The Portrait of Professor Andrea Ferrari](https://cancerworld.net/the-person-behind-the-legend-the-portrait-of-professor-andrea-ferrari/) - A deeply human portrait of Professor Andrea Ferrari — pediatric oncologist, sarcoma leader, AYA advocate, mentor, and visionary behind Progetto Giovani.
- [CancerWorld #110 (December 2025)](https://cancerworld.net/cancerworld-110-december-2025/) - CancerWorld’s December issue explores the human stories, scientific breakthroughs, and policy shifts shaping modern oncology, from pioneers to patients.
- [Surviving Childhood Cancer in Uganda: The Dual Battle for Life and Fertility](https://cancerworld.net/surviving-childhood-cancer-in-uganda-the-dual-battle-for-life-and-fertility/) - A powerful look at childhood cancer survival in Uganda and the growing need for fertility preservation, mental health support, and survivor-centered care.
- [The Other Fight: Confronting Workplace Discrimination Against Cancer Survivors](https://cancerworld.net/the-other-fight-confronting-workplace-discrimination-against-cancer-survivors/) - Cancer survivors still face workplace discrimination worldwide. Learn about global laws, real cases, protections, and how to fight bias after a cancer diagnosis
- [Shrenik Shah: The Voice That Transcends Sound](https://cancerworld.net/shrenik-shah-the-voice-that-transcends-sound/) - A powerful story of Shrenik Shah, a stage IV laryngeal cancer survivor who lost his voice yet transformed silence into global impact through resilience and advocacy.
- [Meet the Man Decoding the Origins of Cancer](https://cancerworld.net/meet-the-man-decoding-the-origins-of-cancer/) - Discover how Dr. Ludmil Alexandrov is decoding cancer’s origins using mutational signatures—advancing prevention, early detection, and targeted treatments.
- [AI Model Shows Promise in Identifying Breast Cancer Patients Who Can Safely Avoid Sentinel Node Biopsy](https://cancerworld.net/ai-model-shows-promise-in-identifying-breast-cancer-patients-who-can-safely-avoid-sentinel-node-biopsy/) - AI model using full-breast mammograms shows promise in predicting lymph node metastasis, potentially allowing over 40% of breast cancer patients to avoid sentinel node biopsy.
- [AI in Oncology Clinical Decision Support](https://cancerworld.net/ai-in-oncology-clinical-decision-support/) - Discover how AI is transforming oncology clinical decision support — from ASCO’s Gemini assistant to ArteraAI’s prostate cancer breakthroughs.
- [Factors Contributing to Treatment Abandonment in Pediatric Cancer in Pakistan](https://cancerworld.net/factors-contributing-to-treatment-abandonment-in-pediatric-cancer-in-pakistan/) - In this article, we summarize a study by Junaid Jamshed et al., published in the OncoDaily Medical Journal, which investigates the multifaceted causes of treatment abandonment in pediatric cancer patients at a tertiary care hospital in Pakistan. Title: Identifying the Factors Contributing to Treatment Abandonment in Childhood Cancers at a Tertiary Care Hospital in PakistanAuthors:
- [Oral Mucositis in Pediatric Cancer Patients Undergoing Chemotherapy in a Tertiary Care Hospital](https://cancerworld.net/oral-mucositis-in-pediatric-cancer-patients-undergoing-chemotherapy-in-a-tertiary-care-hospital/) - In this article, we summarise a paper by Hijab Shaheen et al., published in the OncoDaily Medical Journal, examining the prevalence, severity, and key risk factors for oral mucositis (OM) in pediatric cancer patients undergoing chemotherapy at a tertiary care hospital in Pakistan. Title: Oral Mucositis in Pediatric Cancer Patients Undergoing Chemotherapy in a Tertiary
- [Colorectal Cancer in LATAM: Rising Burden, Late Diagnosis and Uneven Access](https://cancerworld.net/colorectal-cancer-in-latam-rising-burden-late-diagnosis-and-uneven-access/) - This article summarises a recent OncoDaily Medical Journal report on Mexico’s GI-oncology landscape, covering epidemiology, health-system structure, treatment availability, specialist training, and near-term opportunities. Title: Colorectal Cancer in Latin America: Quick CommentAuthors: Veronica Salais Michaus, Erika Ruiz-GarciaDOI: 10.69690/ODMJ-018-0425-4320 Colorectal cancer (CRC) is accelerating across Latin America (LATAM): it now ranks 3rd in incidence and 2nd
- [Survival Outcomes of Wilms’ Tumour at a Single Tertiary Centre over 15 Years](https://cancerworld.net/survival-outcomes-of-wilms-tumour-at-a-single-tertiary-centre-over-15-years/) - This piece is part of a new series featuring summaries from the OncoDaily Medical Journal, highlighting concise, practice-focused insights across cancer research and care. Title: Survival Outcomes of Wilms’ Tumor in Pediatric Patients Treated at KFMC: A Retrospective Study of 15 years from 2007–2022Authors: Omer Alnour et al.DOI: 10.69690/ODMJ-001-0809-4599Full article In a 15-year, single-centre cohort
- [To Stand, To Move, To Live: Musculoskeletal Health as part of the Cancer Journey](https://cancerworld.net/to-stand-to-move-to-live-musculoskeletal-health-as-part-of-the-cancer-journey/) - Musculoskeletal health is vital in the cancer journey, helping prevent fractures, improve mobility, reduce sarcopenia, and enhance quality of life for patients.
- [The Oral Microbiome as a Non-Invasive Biomarker for Early Detection of Pancreatic Cancer Risk](https://cancerworld.net/the-oral-microbiome-as-a-non-invasive-biomarker-for-early-detection-of-pancreatic-cancer-risk/) - New research links 27 oral microbiome species to a 3.5-fold higher pancreatic cancer risk. Learn how saliva-based biomarkers may improve early detection.
- [Muscle-Invasive Bladder Cancer: Evolving Therapies and Access Gaps](https://cancerworld.net/muscle-invasive-bladder-cancer-evolving-therapies-and-access-gaps/) - In this article, we summarise a paper by Yüksel Ürün et al., published in the OncoDaily Medical Journal, on evolving therapies for MIBC and real-world access gaps in Turkey. Title: Muscle-Invasive Bladder Cancer: Evolving Therapies and Real-World Access Gaps in TurkeyAuthors: Yüksel Ürün et al.DOI: 10.69690/ODMJ-002-0912-5113Full article Cystoscopy/TURBT with CT or MRI remains the diagnostic
- [Gastrointestinal Oncology in Mexico: Incidence, Access, and the Path to Equity](https://cancerworld.net/gastrointestinal-oncology-in-mexico-incidence-access-and-the-path-to-equity/) - In this article, we summarise a paper by Alejandro Noguez-Ramos et al., published in the OncoDaily Medical Journal, outlining Mexico’s GI-oncology landscape, epidemiology, health-system structure, treatment availability, training, and near-term opportunities. Title: Gastrointestinal oncology in MexicoAuthors: Alejandro Noguez-Ramos et al.DOI: 10.69690/ODMJ-002-0425-340Full article Mexico’s gastrointestinal (GI) oncology profile differs from regional and global patterns. Compared with
- [Prevent, Treat, Support: An Interview with MEP Tilly Metz](https://cancerworld.net/prevent-treat-support-an-interview-with-mep-tilly-metz/) - Interview with MEP Tilly Metz on Europe’s cancer policy: prevention, HPV elimination, patient rights, health equity, and the future of Europe’s Beating Cancer Plan.
- [Umberto Veronesi and the European School Of Oncology](https://cancerworld.net/umberto-veronesi-and-the-european-school-of-oncology/) - How Umberto Veronesi founded the European School of Oncology, uniting Europe’s cancer research, training, and innovation into a shared vision of better care
- [Princess Dina: The Voice for The Voiceless](https://cancerworld.net/princess-dina-the-voice-for-the-voiceless/) - Princess Dina Mired of Jordan, global health leader and cancer advocate, champions equity, patient voices, and universal access to cancer care.
- [How AI is Assisting, Not Replacing Radiologists](https://cancerworld.net/how-ai-is-assisting-not-replacing-radiologists/) - Artificial intelligence is transforming radiology by assisting—not replacing—radiologists, enhancing diagnostics, efficiency, and accuracy in medical imaging.
- [Hashtags and Clarity: Transforming social media into a source of truth for oncology patients](https://cancerworld.net/hashtags-and-clarity-transforming-social-media-into-a-source-of-truth-for-oncology-patients/) - How social media and AI are reshaping cancer care, empowering patients but fueling misinformation. A deep look at risks, realities, and solutions.
- [Princess Ghida: Where Hope Wears a Crown](https://cancerworld.net/princess-ghida-where-hope-wears-a-crown/) - An in-depth interview with HRH Princess Ghida Talal of Jordan on her leadership in cancer care, health equity, global advocacy, and transforming oncology across the Arab world.
- [CancerWorld #109 (November 2025)](https://cancerworld.net/cancerworld-109-november-2025/) - Explore the CancerWorld #109 (November) issue featuring global leaders in oncology, innovation, policy, and survivorship.
- [Respiratory Infections Trigger Metastatic Breast Cancer in the Lungs](https://cancerworld.net/respiratory-infections-trigger-metastatic-breast-cancer-in-the-lungs/) - New Nature study finds COVID-19 and flu can awaken dormant breast cancer cells in the lungs, raising risks of metastasis and mortality.
- [Felicia Marie Knaul: A Researcher Shaped by Experience](https://cancerworld.net/felicia-marie-knaul-a-researcher-shaped-by-experience/) - Discover the inspiring journey of Dr. Felicia Marie Knaul—cancer survivor, global health advocate, and leader reshaping access to care worldwide.
- [GI Cancer in Guatemala: Risks, Care Gaps, and Priorities](https://cancerworld.net/gi-cancer-in-guatemala-risks-care-gaps-and-priorities/) - In this article, we summarise a paper by Rixci Augusto Ramírez Fallas et al., published in the OncoDaily Medical Journal, offering a system-level view of gastrointestinal (GI) cancers in Guatemala, epidemiology, risk factors, care capacity, and priorities for prevention and early detection. Title: Current Perspective of Gastrointestinal Cancer in GuatemalaAuthors: Rixci Augusto Ramírez Fallas et
- [Metastatic Melanoma: Five Decades of Treatment Progress](https://cancerworld.net/metastatic-melanoma-five-decades-of-treatment-progress/) - In this article, we summarise a paper by Agop Y. Bedikian, published in the OncoDaily Medical Journal, tracing how care for metastatic cutaneous melanoma moved from cytotoxic agents to precision targets and immune checkpoint blockade, and what still limits durable control. Title: Evolution of the Treatment of Metastatic Cutaneous Melanoma over the Past 5 DecadesAuthor:
- [From Engineering to Oncology:  A Life Shaped by Patients, Science, and Service](https://cancerworld.net/from-engineering-to-oncology-a-life-shaped-by-patients-science-and-service/) - In this article, we summarise a paper by Agop Y. Bedikian, published in the OncoDaily Medical Journal, tracing the personal journey of an Armenian-Lebanese engineering student who became a cancer specialist, and how patient-centered care and clinical trials defined his career. Title: Aspiring engineer who would be a cancer specialistAuthor: Agop Y. BedikianDOI: 10.69690/ODMJ-003-1024-221Full article
- [Hematologic Oncology in Armenia: Progress, Bottlenecks, and What’s Next](https://cancerworld.net/hematologic-oncology-in-armenia-progress-bottlenecks-and-whats-next/) - In this article, we summarise a paper by Alisa Movsisyan et al., published in the OncoDaily Medical Journal, offering the first nationwide overview of hematologic oncology in Armenia, covering epidemiology, diagnostics, treatment, outcomes, and system gaps that shape care across the country. Title: The Experience of Hematologic Oncology in ArmeniaAuthors: Alisa Movsisyan et al.DOI: 10.69690/ODMJ-001-1124-250Full
- [From Imatinib to CAR-T: 20 Years of Leukaemia Progress](https://cancerworld.net/from-imatinib-to-car-t-20-years-of-leukaemia-progress/) - Advances in leukaemia treatment have accelerated from first-generation chemotherapy to precision targets and cellular immunotherapy. In this article, we summarise a paper by Robert Peter Gale, published in the OncoDaily Medical Journal, tracing that evolution across ALL, AML, CLL, and CML. Title: New Leukaemia DrugsAuthor: Robert Peter GaleDOI: 10.69690/ODMJ-003-0924-142Full article Over the past two decades,
- [Does Uncertainty Inherently Cause Burnout Among Oncology Care Providers?](https://cancerworld.net/does-uncertainty-inherently-cause-burnout-among-oncology-care-providers/) - A deeply human reflection on oncology burnout, compassion fatigue, and guilt among cancer care professionals. This article explores the emotional toll of uncertainty, advocacy, and the struggle to care for oneself while caring for others in oncology.
- [A Place to Sleep, A Chance to Heal: How Hostels and Transport Help Children Beat Cancer in Africa](https://cancerworld.net/a-place-to-sleep-a-chance-to-heal-how-hostels-and-transport-help-children-beat-cancer-in-africa/) - How hostels and free transport give children with cancer in Africa a fighting chance—providing shelter, hope, and access to life-saving treatment.
- [Paul Mischel: Calming Full Circle](https://cancerworld.net/paul-mischel-calming-full-circle/) - Prof. Paul Mischel’s groundbreaking work on extra-chromosomal DNA (ecDNA), his remarkable career, and his life’s purpose of transforming cancer research.
- [CancerWorld #107 (September 2025)](https://cancerworld.net/cancerworld-107-september-2025/) - CancerWorld is not only about cells and treatments. It is about hope, endurance, and the voices that shape the fight against cancer—patients, doctors, scientists, advocates, families, caregivers, and the unsung heroes dedicating their lives to oncology. In this issue, we bring them all to your radar. Our grand opening features Dr. Patrick Soon-Shiong, one of
- [Fedro Peccatori Between Science and the Human Heart](https://cancerworld.net/fedro-peccatori-between-science-and-the-human-heart/) - Professor Fedro Peccatori’s journey reveals oncology as both science and human art—bridging fertility, pregnancy, education, and compassion in cancer care.
- [Artificial Sweetener Reduces Response to Immunotherapy](https://cancerworld.net/artificial-sweetener-reduces-response-to-immunotherapy/) - New study links the artificial sweetener sucralose to reduced cancer immunotherapy response. Learn how diet impacts treatment and arginine may help recovery.
- [The Life Journey of Giuseppe Curigliano: From Becoming an Expert to Making Experts](https://cancerworld.net/the-life-journey-of-giuseppe-curigliano-from-becoming-an-expert-to-making-experts/) - The Story of Prof. Giuseppe Curigliano, from Rome to leading ESMO. A story of science, mentorship, and courage that shaped modern oncology
- [CancerWorld #108 (October 2025)](https://cancerworld.net/cancerworld-108-october-2025/) - Explore CancerWorld’s October 2025 issue—featuring Giuseppe Curigliano, Fedro Peccatori, and Felicia Marie Knaul on leadership, equity, and humanity in cancer care.
- [From Oceans to Organs: The Alarming Cancer Risks of Microplastics](https://cancerworld.net/from-oceans-to-organs-the-alarming-cancer-risks-of-microplastics/) - Microplastics pollute oceans, food & organs, raising cancer risks via inflammation, DNA damage & toxins. Learn health impacts & urgent solutions.
- [Social Media in Oncology – Between Empowerment and Risk](https://cancerworld.net/social-media-in-oncology-between-empowerment-and-risk/) - Discover how social media impacts oncology, empowering patients with connection and knowledge while posing risks of misinformation.
- [The Apparent Cancer Paradox of Latvia](https://cancerworld.net/the-apparent-cancer-paradox-of-latvia/) - Latvia faces high cancer death rates yet reports unexpected survival successes. Explore the paradox of risk, diet, healthcare, and data gaps.
- [Could Radiotherapy Offer Unexpected Protection Against Alzheimer’s Disease?](https://cancerworld.net/could-radiotherapy-offer-unexpected-protection-against-alzheimers-disease/) - A JAMA Network Open study shows breast cancer survivors have an 8% lower risk of Alzheimer’s disease, with radiation therapy linked to a 23% risk reduction.
- [Detecting Cancer Before It Strikes: The Promise of Combination Early Detection and Interception](https://cancerworld.net/detecting-cancer-before-it-strikes-the-promise-of-combination-early-detection-and-interception/) - Discover how combination early cancer detection and interception—using molecular biomarkers, liquid biopsies, AI, and multi-cancer screening—could transform cancer prevention and save lives.
- [What About Them, the Caregivers?](https://cancerworld.net/what-about-them-the-caregivers/) - Discover the hidden burdens and rewards of cancer caregiving. Learn how caregivers balance emotional, medical, and personal challenges while finding resilience and meaning.
- [She’s Gone and Done It: The Story of Dr. Nageatte Ibrahim](https://cancerworld.net/shes-gone-and-done-it-the-story-of-dr-nageatte-ibrahim/) - Discover Dr. Nageatte Ibrahim’s journey from multicultural roots to leading Keytruda’s development, revolutionizing cancer treatment with global impact.
- [Large-scale whole genome sequencing identifies six new cancer susceptibility/ resistance  genes](https://cancerworld.net/large-scale-whole-genome-six-new-cancer-genes/) - Six previously unreported genes have been revealed to harbour rare germline mutations that associate with cancer risk. The study, published in Nature Genetics, 29 October, identified 34 genes associated with cancer risk, including four novel genes associated with increased cancer risk and two genes associated with decreased cancer risk. “Overall, our study demonstrates the power
- [ESO College Voices Contest 2025: Social media – friend or foe for cancer patients? – Winners Announced](https://cancerworld.net/eso-college-voices-contest-2025-social-medias-role-in-cancer-care-winners-announced/) - This year’s ESO College Voices Contest proved once again that doctors can also be excellent cancer writers. For this year’s contest, we received 27 proposals from ESO College members across 20 countries, each elaborating on the chosen topic: "Social media – friend or foe for cancer patients?" Many proposals examined similar effects of social media on
- [Antidepressants Show Potential to  Fight Cancer](https://cancerworld.net/antidepressants-show-potential-to-fight-cancer/) - Antidepressants like SSRIs show promise in boosting T cells, shrinking tumors, and improving survival rates—opening new paths in cancer immunotherapy.
- [Patrick Soon-Shiong: He Who Speaks for the People](https://cancerworld.net/patrick-soon-shiong-he-who-speaks-for-the-people/) - If you describe yourself in one sentence, what would it look like? I wish I could have been Kobe Bryant. Who is your role model? I wish I could have been Kobe Bryant. And what is your dream? I wish I could have been Kobe Bryant. *** When I entered the room to meet Dr.
- [I Am Alive: Letter to Oncologists](https://cancerworld.net/i-am-alive-letter-to-oncologists/) - Cancer survivor shares her journey of healing, blending medical treatment and emotional support, urging oncologists to embrace heart-centred care with science
- [The Story of Dr. Anne Merriman: Pioneering Compassion and Dignity in Africa’s Palliative Care Revolution](https://cancerworld.net/the-story-of-dr-anne-merriman-pioneering-compassion-and-dignity-in-africas-palliative-care-revolution/) - Discover the inspiring story of Dr. Anne Merriman, a pioneer of palliative care in Africa, and her legacy in transforming end-of-life care across the continent.
- [Beyond the Data: The Art of Personalized Hope](https://cancerworld.net/beyond-the-data-the-art-of-personalized-hope/) - Together with Albertina explore how data and algorithms shape cancer care, highlighting the importance of hope and personalized care in the fight against cancer
- [Curious, Rejected,Accepted: An ESO Fellow’s Road to Becoming an Oncologist](https://cancerworld.net/curious-rejectedaccepted-an-eso-fellows-road-to-becoming-an-oncologist/) - Discover how the European School of Oncology (ESO) transformed Dr. Amalya Sargsyan's journey through mentorship, global training, and relentless opportunity.
- [The Unstoppable Jay: Jayasree K. Iyer’s Global Crusade for Equitable Cancer Care](https://cancerworld.net/the-unstoppable-jay-jayasree-k-iyers-global-crusade-for-equitable-cancer-care/) - Discover the inspiring story of Jayasree Iyer, CEO of the Access to Medicine Foundation, leading the fight for global cancer care equity and access medications
- [When Hope is Hard to Find, Folk Remedies Step In](https://cancerworld.net/when-hope-is-hard-to-find-folk-remedies-step-in/) - Explore the reliance on folk remedies in Europe, the cultural and systemic factors driving this trend, and the need for better education and healthcare access
- [Six Months of CancerWorld Under p53: A Report of Renewal, Responsibility, and Reach](https://cancerworld.net/six-months-of-cancerworld-under-p53-a-report-of-renewal-responsibility-and-reach/) - Dear Readers, Six months ago, we embarked on a journey, ambitious, humbling, and deeply meaningful. In January 2025, CancerWorld, one of Europe’s most prestigious oncology publications, entered a new chapter under the ownership of p53 (OncoDaily). With that acquisition came a promise: to carry forward a legacy built by the European School of Oncology and
- [Michel Goldman: A Teacher Until the End](https://cancerworld.net/michel-goldman-a-teacher-until-the-end/) - Renowned immunologist Michel Goldman, lymphoma patient and science leader, shares his journey from pioneering drug innovation to championing patient voices.
- [CancerWorld #106 (August 2025)](https://cancerworld.net/cancerworld-106-august-2025/) - From breakthrough iNKT cell therapy to global access gaps, CancerWorld’s Aug 2025 issue explores science, equity, AI survival prediction, and patient voices.
- [Cancer Neuroscience: How Neurons Fuel Tumor Growth, and What it Means for Therapy](https://cancerworld.net/cancer-neuroscience-how-neurons-fuel-tumor-growth-and-what-it-means-for-therapy/) - Brain Prize winners Frank Winkler & Michelle Monje uncover how neurons fuel tumor growth, pioneering cancer neuroscience for future therapies.
- [BRCA1/BRCA2 Mutations Carriers at Greater Risk for Anaplastic Large Cell Lymphoma Associated with Breast Implants](https://cancerworld.net/brca1-brca2-mutations-carriers-at-greater-risk-for-anaplastic-large-cell-lymphoma-associated-with-breast-implants/) - Women with BRCA1/2 mutations face a 16× higher risk of rare lymphoma from textured breast implants, new MSKCC study warns. Know your risk and history.
- [How a Simple Photo Can Help Predict Survival in Cancer Patients: The FaceAge AI](https://cancerworld.net/how-a-simple-photo-can-help-predict-survival-in-cancer-patients-the-faceage-ai/) - Harvard’s FaceAge AI predicts cancer survival from a single photo, revolutionizing prognosis and guiding treatment in oncology and palliative care.
- [Jennifer Buell: Turning Living Cells into Living Medicines](https://cancerworld.net/jennifer-buell-turning-living-cells-into-living-medicines/) - Meet Jennifer Buell, CEO of MiNK Therapeutics, who redifines cancer care with pioneering iNKT cell therapies that unite scientific brilliance and global access.
- [Empowering Patients in Europe’s New Health Technology Assessment](https://cancerworld.net/empowering-patients-in-europes-new-health-technology-assessment/) - EU’s new Health Technology Assessment regulation aims to harmonize treatment evaluations and empower patients, but will it truly improve equity across Europe?
- [A Bold Step into Building Africa’s Cancer Atlas](https://cancerworld.net/a-bold-step-into-building-africas-cancer-atlas/) - Africa's Cancer Atlas aims to sequence 15,000 cancer genomes, boosting African data in global research and advancing equity in cancer diagnosis and treatment
- [Cannabis Use is Linked to Increased Mortality in Colon Cancer Patients](https://cancerworld.net/cannabis-use-is-linked-to-increased-mortality-in-colon-cancer-patients/) - Study finds colon cancer patients with cannabis use disorder face dramatically higher mortality rates, raising urgent questions for oncology and public health.
- [Can Healing and Growth Coexist? Post-Traumatic Transformation in Cancer Patients](https://cancerworld.net/can-healing-and-growth-coexist-post-traumatic-transformation-in-cancer-patients/) - Cancer isn’t just physical—it's emotional and existential. Explore how post-traumatic growth helps patients transform trauma into resilience, meaning, and healing.
- ["Moving Mountains with Passion": The Life and Legacy of Baroness Françoise Meunier](https://cancerworld.net/moving-mountains-with-passion-the-life-and-legacy-of-baroness-francoise-meunier/) - The inspiring life of Baroness Françoise Meunier, who transformed cancer research in Europe and now champions the rights of survivors across the continent.
- [Fighting Cervical Cancer in Latin America’s Indigenous Communities: The Case for More Research and Tailored Programs ](https://cancerworld.net/fighting-cervical-cancer-in-latin-americas-indigenous-communities-the-case-for-more-research-and-tailored-programs/) - Indigenous women in Latin America face the region’s highest cervical cancer death rates due to limited access. Culturally tailored programs aim to change that.
- [“I’m Here”: The Story of George Kapetanakis](https://cancerworld.net/im-here-the-story-of-george-kapetanakis/) - The inspiring story of George Kapetanakis, a cancer survivor and president of ELLOK, whose leadership has transformed Greek healthcare and patient advocacy.
- [How a Brain-Destroying Protein Became Cancer’s Ally: Alpha-Synuclein Emerges as a New Target in Melanoma](https://cancerworld.net/how-a-brain-destroying-protein-became-cancers-ally-alpha-synuclein-emerges-as-a-new-target-in-melanoma/) - The alpha-synuclein, a protein long associated with Parkinson’s disease may hold the key to melanoma proliferation. The study, published in Science Advances, on 9 April, suggests that while excess alpha-synuclein results in cell death in neurons, conversely, it enables uncontrolled growth in melanoma cells. “This [study] provides a framework for understanding the link between Parkinson’s
- [Suheir Rasul: Protecting Human Dignity](https://cancerworld.net/suheir-rasul-protecting-human-dignity/) - From conflict zones to cancer care, Suheir Rasul leads with empathy and purpose, transforming global childhood health through storytelling and advocacy.
- [Equity:The Word That Shaped Her Career From The Lab To The White House:The Story Of Catharine Young](https://cancerworld.net/equitythe-word-that-shaped-her-career-from-the-lab-to-the-white-housethe-story-of-catharine-young/) - Catharine Young's journey from apartheid-era South Africa to leading U.S. cancer policy highlights her mission for global health equity.
- [The Dawn of Empathetic Intelligence in Oncology](https://cancerworld.net/the-dawn-of-empathetic-intelligence-in-oncology/) - Meet Albertina, the empathetic Intelligence at the forefront of a new era in oncology.
- [CancerWorld #105 (July 2025)](https://cancerworld.net/cancerworld-105-july-2025/) - At CancerWorld, we believe the future of oncology is shaped not only by what we discover but by how we care, who we listen to, and what we choose to build. On our dual cover, we feature Suheir Rasul. As Senior Vice President of ALSAC Global, the fundraising and awareness arm of St. Jude Children’s
- [Agents of Mutation: Pathogens as Catalysts of Carcinogenesis](https://cancerworld.net/pathogen-related-cancer/) - Pathogen-related cancer affects millions globally. Discover how viruses, bacteria, and parasites act as hidden drivers of tumor growth and cancer evolution.
- [Towards a Familial Cancer Service for Chile](https://cancerworld.net/towards-a-familial-cancer-service-for-chile/) - A Familial Cancer Service for Chile is being piloted to improve genetic testing, counselling, and early detection of hereditary cancer across the country.
- [Traditional Chinese Medicine: Building a Bridge to Modern Oncology](https://cancerworld.net/traditional-chinese-medicine-building-a-bridge-to-modern-oncology/) - Explore how Traditional Chinese Medicine in oncology is reshaping cancer treatment in China, bridging ancient wisdom with modern science for integrated patient care.
- [How a Chicken Egg Model Could Transform Pediatric Cancer Treatment in Canada](https://cancerworld.net/how-a-chicken-egg-model-could-transform-pediatric-cancer-treatment-in-canada/) - Discover how a chicken egg model is revolutionizing pediatric cancer treatment in Canada with faster, personalized therapies for rare childhood cancers
- [Microbiota-Derived Bile Acids as Androgen Receptor Antagonists Enhance Anti-Tumour Immunity](https://cancerworld.net/microbiota-derived-bile-acids-as-androgen-receptor-antagonists-enhance-anti-tumour-immunity/) - Microbiota-derived bile acids block androgen receptors, enhancing anti-tumour immunity and boosting response to anti-PD1 therapy, study shows.
- [Back on Screen: The Return of Smoking in Films and Its Public Health Implications](https://cancerworld.net/back-on-screen-the-return-of-smoking-in-films-and-its-public-health-implications/) - In recent years, smoking in films has made a bold return, reversing a decade-long decline influenced by health concerns and policies restricting tobacco imagery
- [Alberto Costa: The Father of Seven Children](https://cancerworld.net/alberto-costa-the-father-of-seven-children/) - Read about the life, legacy, career and love stories of legendary Alberto Costa, breast surgeon, mentor, founder of ESO, and father of seven.
- [Is It Biology or Geography That Decides Who Survives Childhood Cancer?](https://cancerworld.net/is-it-biology-or-geography-that-decides-who-survives-childhood-cancer/) - Every year, over 400,000 children are diagnosed with cancer. The vast majority live in LMICs. And most of them will die because the medicine doesn’t reach them.
- [Matti Aapro: An Oncologist Who Needs No Introduction](https://cancerworld.net/matti-aapro-an-oncologist-who-needs-no-introduction/) - Discover the extraordinary journey of Prof. Matti Aapro, from the beaches of Rio to the forefront of global oncology leadership.
- [Zainab Shinkafi-Bagudu: What Africa’s First Lady of Cancer Will Bring to the Top Global Advocacy Role](https://cancerworld.net/zainab-shinkafi-bagudu-what-africas-first-lady-of-cancer-will-bring-to-the-top-global-advocacy-role/) - Zainab Shinkafi-Bagudu, Africa’s leading cancer advocate, brings decades of frontline experience to her role as the next UICC President in 2026.
- [Strategies Needed to Prioritise Screening in Survivors of Childhood Cancer](https://cancerworld.net/strategies-needed-to-prioritise-screening-in-survivors-of-childhood-cancer/) - Survivors of childhood cancer face early-onset chronic diseases. Experts urge earlier screening and prevention strategies to address accelerated aging risks.
- [CancerWorld #104 (June 2025)](https://cancerworld.net/cancerworld-104-june-2025/) - Discover the CancerWorld #104 (June 2025) issue, that brings our founding philosophy into sharp focus: CancerWorld is not about papers, it’s about people
- [Princess Adila: Her Royal Highness, Her Human Mission](https://cancerworld.net/princess-adila-bint-abdullah-al-saud-cancer-world/) - Discover the inspiring story of Princess Adila bint Abdullah Al Saud, her humanitarian mission, cancer advocacy, women’s empowerment, and quiet leadership.
- [Albinism And Skin Cancer In Africa: Tackling The Prevention Needs Of A Stigmatised Population](https://cancerworld.net/albinism-and-skin-cancer-in-africa-tackling-the-prevention-needs-of-a-stigmatised-population/) - People with albinism in Africa are at increased risk of skin cancer.Explore prevention challenges and support initiatives for albinism and skin cancer in Africa
- [Common Diabetes Medication Could Protect Heart Health During Cancer Treatment](https://cancerworld.net/common-diabetes-medication-may-protect-heart-health-during-cancer-treatment/) - Sodium-glucose cotransporter 2 (SGLT2) inhibitors, a common type of diabetes medication, may protect the heart during and after cancer treatment.
- [“I really care about people.” – Philip Kantoff, A Life in Science and Medicine](https://cancerworld.net/philip-kantoff-i-really-care-about-people/) - Explore the career of Dr. Philip Kantoff, prostate cancer pioneer, biotech founder, and mentor, whose work has shaped modern oncology and radiopharmaceuticals.
- [Why Patient-Reported Outcomes are Rarely Used in Trials, and How We Change That](https://cancerworld.net/why-patient-reported-outcomes-are-rarely-used-in-trials-and-how-we-change-that/) - Why aren't patient-reported outcomes used more in trials? Exploring barriers, solutions, and how PROs can improve drug development and approval.
- [A Promise Kept: How Samvel Danielyan Lifted Pediatric Cancer Survival from Zero to 70%](https://cancerworld.net/a-promise-kept-how-samvel-danielyan-lifted-pediatric-cancer-survival-from-zero-to-70/) - In war-torn Armenia, Dr. Samvel Danelyan raised pediatric cancer survival from 0% to 70%. Read the inspiring story of one doctor’s mission that saved thousands.
- [Together, She Changed Everything: Martine Piccart ’s Fight Against Breast Cancer](https://cancerworld.net/together-she-changed-everything-martine-piccart-s-fight-against-breast-cancer/) - Martine Piccart grew up in a house where medicine was part of the air. Her father, a gynecologist, treated patients at home. “I admired him deeply,” she says.
- [It’s no longer taboo to suggest that some metastatic breast cancers may be curable](https://cancerworld.net/its-no-longer-taboo-to-suggest-that-some-metastatic-breast-cancers-may-be-curable/) - It’s long been clear that, in most patients with metastatic HER-positive breast cancer, adding effective HER2 blockade to cytotoxics can result in very prolonged responses. Janet Fricker reports on the prospective trials building evidence on whether – and in whom – these responses could amount to a cure. When Yvonne Fantaci was diagnosed with metastatic
- [(Re)Thinking Psycho-oncology in a world out of balance: What I learned after a year of interviews](https://cancerworld.net/rethinking-psycho-oncology-in-a-world-out-of-balance-what-i-learned-after-a-year-of-interviews/) - "One must imagine Sisyphus happy" Albert Camus Why me? This is probably the present-day question of every patient with cancer! One of the consequences of our chaotic reality is cancer, which belongs to that class of diseases that impacts the mental health of the patient and their family; life after the oncological diagnosis will never
- [What Caught Our Eye in April: Oncology’s Top Moments](https://cancerworld.net/what-caught-our-eye-in-april-oncologys-top-moments/) - April 2025 marked a significant month in oncology, with notable advancements in cancer treatment and research. Here’s a summary of the most compelling studies and recent breakthroughs that caught our eye this month. Popular CT scans could account for 5% of all cancer cases a year A recent study from the University of California, San
- [Adrian Gottschalk: Making a Difference for His Fellow Human Beings](https://cancerworld.net/adrian-gottschalk-making-a-difference-for-his-fellow-human-beings/) - I grew up around a lot of physicians,” begins Adrian Gottschalk, President and CEO of Foghorn Therapeutics, a biotech company redefining how we understand and treat complex diseases by targeting the chromatin regulatory system. “My late father was a professor of orthopedic surgery at the medical school in Dallas, Texas. Science and medicine were always
- [A Vision for Cancer Policy in Europe: An Interview with MEP Nikos Papandreou](https://cancerworld.net/a-vision-for-cancer-policy-in-europe-an-interview-with-mep-nikos-papandreou/) - CancerWorld had the opportunity to interview Nikos Papandreou, Member of the European Parliament and a dedicated advocate for cancer policy reform. With a background in politics, economics, and healthcare policy, Mr. Papandreou has been at the forefront of tackling Europe’s cancer challenges. As a member of the SANT Committee, he is working to drive meaningful
- [CancerWorld issue #103 (May, 2025)](https://cancerworld.net/cancerworld-103-may-2025/) - What does it take to change the odds in cancer care? Innovation? Yes. But also: persistence. Collaboration. The refusal to accept that some lives matter less because of where they’re born. In this issue of CancerWorld, we focus not just on what’s new in oncology, but on what’s necessary. Our dual cover stories frame that
- [ACT for Children:A Global Initiative to Tackle Inequities in Pediatric Cancer](https://cancerworld.net/act-for-childrena-global-initiative-to-tackle-inequities-in-pediatric-cancer/) - The disparity in childhood cancer outcomes is one of the world’s most pressing health inequities. While over 80% of children with cancer are cured in high-income countries (HICs), survival drops to less than 30% in low- and middle-income countries (LMICs). This gap is not due to a lack of curative potential, but rather to unequal
- [What Caught Our Eye in March: Oncology's Top Moments](https://cancerworld.net/what-caught-our-eye-in-march-oncologys-top-moments/) - March saw the publication of several important studies in oncology, shedding new light on cancer treatment and care. Here’s a roundup of the key studies on recent discoveries and breakthroughs that grabbed our attention this month. Small device, big impact: Improving the safety of life-saving treatments for children with leukemia In a groundbreaking study published
- [Personalised neoantigen vaccine for kidney cancer shows promise in phase 1 study](https://cancerworld.net/personalised-neoantigen-vaccine-for-kidney-cancer-shows-promise-in-phase-1-study/) - Personalised neoantigen cancer vaccines (both with and without ipilimumab) elicited anticancer immune responses in nine patients with fully resected clear cell renal cell carcinoma. The investigator-initiated phase 1 trial, published in Nature, February 5 2025, observed no recurrences at a median follow-up of 40.2 months following surgery. “In this study, we were really encouraged to
- [Miriam Merad and the 2025 Sjöberg Prize: A Celebration of Innovation in Cancer Immunotherapy](https://cancerworld.net/miriam-merad-and-the-2025-sjoberg-prize-a-celebration-of-innovation-in-cancer-immunotherapy/) - Every year, the Sjöberg Prize, established by the Royal Swedish Academy of Sciences, honors researchers whose scientific discoveries in oncology are reshaping the understanding and treatment of cancer. The award stands alongside the most prestigious accolades in science, not only highlighting landmark breakthroughs but fueling ongoing innovation. In 2025, the prize was awarded to Dr.
- [What If the World’s Leading Prostate Cancer Epidemiologist Opened a Restaurant?  A Conversation with Lorelei Mucci- A Harvard Scientist, A Mother, A Leader](https://cancerworld.net/what-if-the-worlds-leading-prostate-cancer-epidemiologist-opened-a-restaurant-a-conversation-with-lorelei-mucci-a-harvard-scientist-a-mother-a-leader/) - I always close my interviews with a signature question: "Who should I speak with next?"It’s a small but revealing moment — a window into whom the giants of oncology admire, learn from, and find truly compelling. When I posed the question to Dr. Philip Kantoff, his answer came without hesitation:"My wife, Lorelei Mucci." It wasn’t
- [CancerWorld #102 (April 2025)](https://cancerworld.net/cancerworld-102-april-2025/) - The People Behind the Progress in Oncology is science. But it is also stories. It is policy. It is power. It is knowledge. It is culture. It is trust. And above all, it’s personal. This is the lens through which we bring you to look at this April 2025 issue—an edition that spans leadership-defining careers,
- [Owning our successes is how we secure the future of Europe’s Beating Cancer Plan](https://cancerworld.net/owning-our-successes-is-how-we-secure-the-future-of-europes-beating-cancer-plan/) - A surge in actions across the EU to improve cancer prevention, screening, and care of patients and survivors shows the success of Europe’s Beating Cancer Plan. We know that. To ensure continued support for cancer in the next seven-year funding cycle, we need to make sure others know it as well, says ECO’s policy lead,
- [Key link identified in mechanism promoting lung metastases from breast cancer](https://cancerworld.net/key-link-identified-in-mechanism-promoting-lung-metastases-from-breast-cancer/) - The amino acid aspartate has been found to function as an extracellular signalling molecule to promote lung metastases in breast cancer. The study, published in Nature, 1 January, which was undertaken in mice and postmortem human tissue, showed evidence for an alternative “translation program” that results in increased aspartate levels in the lung leading to
- [MRI technique can identify pre-malignant pancreatic lesions](https://cancerworld.net/mri-technique-can-identify-pre-malignant-pancreatic-lesions/) - Diffusion tensor imaging (DTI), a form of MRI, is capable of detecting pre-malignant lesions in both mouse and human pancreatic specimens. The ‘proof of concept’ study, published in Investigative Radiology, 13 December 2024, opens the way to use DTI for early diagnosis in people at risk of pancreatic cancer, and to understand more about carcinogenesis.
- [Low-dose aspirin reduces colorectal cancer recurrence in patients with PI3K alterations](https://cancerworld.net/low-dose-aspirin-reduces-colorectal-cancer-recurrence-in-patients-with-pi3k-alterations/) - Taking adjuvant low-dose aspirin daily for three years reduced recurrence of colorectal cancer by 55% in patients with somatic alterations in PI3K signalling compared to those taking placebo. The results of the ALASCCA study, presented at the 2025 ASCO Gastrointestinal Cancers Symposium in San Francisco, 23 to 25 January, could lead to immediate changes in
- [Could this dual approach be the frontier that finally gets immunotherapy to work for MSS colorectal cancer?](https://cancerworld.net/botensilimab-and-balstilimab-for-mss-colorectal-cancer/) - It is often said in medicine that the only true constant in facing life-threatening diseases is change. Nowhere is this more evident than in oncology, where advances in chemotherapy, targeted therapies, immunotherapies, and other novel agents continue to spark hope. Yet people still ask: Why isn’t there a universal cure for cancer? Perhaps the question
- [Istanbul, Ankara take action on HPV vaccination, as government delays promised national programme](https://cancerworld.net/istanbul-ankara-take-action-on-hpv-vaccination-as-government-delays-promised-national-programme/) - The two largest cities in Türkiye have stepped in to promote HPV vaccination at a local level, including free inoculation for young people from the poorest families, as the state fails to deliver on its commitment to add HPV to the national vaccination programme. On International HPV Awareness Day, March 4th, the Turkish government faced
- [CancerWorld #101 (February 2025): The Must-Read Oncology Issue Returns to Print with Exclusive Interviews and Breakthroughs](https://cancerworld.net/cancerworld-101-february-2025-the-must-read-oncology-issue-returns-to-print-with-exclusive-interviews-and-breakthroughs/) - After transitioning to a fully digital format in 2022, CancerWorld is making a highly anticipated return to print with its February 2025 issue. This edition delivers in-depth analysis, expert perspectives, and the latest advancements in cancer research, policy, and treatment. This double-sided issue features an in-depth cover story on Dr. Matti Aapro, a pioneer in
- [Sleep & Cancer: Why Rest Matters More Than You Think?](https://cancerworld.net/sleep-cancer-why-rest-matters-more-than-you-think/) - Difficulty sleeping and disturbed sleep patterns are not uncommon among cancer patients, and alleviating these symptoms has always been integral to good cancer care. Now, mounting evidence of the impact that getting enough deep sleep can have on outcomes in some cancers makes it even more important for patients to be given the sleep support
- [Ovarian cancer: mechanism conferring resistance to immunotherapy revealed](https://cancerworld.net/ovarian-cancer-mechanism-conferring-resistance-to-immunotherapy-revealed/) - The presence of flagella, the propellers bacteria use to move, explains why immune checkpoint inhibitors do not work in patients with ovarian cancer. The study, published in Cancer Immunology Research, 11 February, suggests that immune cell recognition of bacterial flagella, mediated by toll-like receptor 5, offers a mechanism intrinsic to the host that underlies the
- [Muscular strength and cardiorespiratory fitness improve survival in cancer patients](https://cancerworld.net/muscular-strength-and-cardiorespiratory-fitness-improve-survival-in-cancer-patients/) - Muscular strength and cardiorespiratory fitness are linked to a significantly lower risk of death from any cause and cancer-specific mortality in patients diagnosed with cancer. The meta-analysis, published online in the British Journal of Sports Medicine, 21st January, found a strong association between high physical fitness levels and reduced all-cause mortality risk in patients with
- [Seeking to get pregnant when the cancer is advanced](https://cancerworld.net/seeking-to-get-pregnant-when-the-cancer-is-advanced/) - Faced with the sudden knowledge that the life they had expected will be suddenly cut short, some women find hope and existential meaning in trying for a child that that will be theirs for their remaining time, and carry their legacy when they are gone. Diana Mwango reports from Kenya on what that choice can
- [How Indian centres slashed treatment drop-out rates in childhood cancer](https://cancerworld.net/how-indian-centres-slashed-treatment-drop-out-rates-in-childhood-cancer/) - Dedicated support from day 1 for families of children diagnosed with cancer has resulted in a reduction in children failing to complete their course of treatment from one in five to one in fifty. The result has been a significant drop in mortality at centres running the programme, writes Swagata Yadavar. Just 15 years ago,
- [OncoDaily Acquires CancerWorld: A New Era in Oncology Media](https://cancerworld.net/oncodaily-acquires-cancerworld-a-new-era-in-oncology-media/) - OncoDaily, a leading oncology media globally, is pleased to announce the acquisition of CancerWorld, one of Europe’s oldest and most respected oncology magazines and online platforms. CancerWorld was established by the European School of Oncology (ESO) and, since 2020, has been successfully managed by SPCC (Sharing Progress in Cancer Care). This transition represents an important
- [China’s integrated cancer care guidelines ‘reflect self-confidence’ in the field of oncology](https://cancerworld.net/chinas-integrated-cancer-care-guidelines-reflect-self-confidence-in-the-field-of-oncology/) - China’s oncologists now have access to guidelines which have been developed specifically for their patient population, incorporating locally generated evidence, and embracing holistic approaches to care, including appropriate use of Chinese traditional medicine. Tina Jiang was at the China Integrative Oncology Conference in Xi’an, last November, to find out more. “For every three cancer patients
- [Europe’s cancer agenda: how we keep it a priority in changing times](https://cancerworld.net/europes-cancer-agenda-how-we-keep-it-a-priority-in-changing-times/) - “I feel I’m among friends… we are all fighting the same battles.” This is how the former European Health Commissioner Stella Kyriakides greeted her audience at the European Cancer Summit at a session on November 20th devoted to her great legacy, the Europe’s Beating Cancer Plan – assessing its achievements, planning how to take it
- [Second-generation BTK inhibitor shows promise as fixed-duration therapy in CLL](https://cancerworld.net/second-generation-btk-inhibitor/) - Treatment with the second-generation Bruton tyrosine kinase (BTK) inhibitor acalabrutinib plus the BCL2 inhibitor venetoclax (with or without the CD20 inhibitor obinutuzumab), delivered as fixed-duration therapies, significantly improved progression free survival in comparison with standard-of-care chemotherapy in previously untreated patients with chronic lymphocytic leukaemia (CLL). Results from the AMPLIFY study, presented at the 2024 ASH
- [New evidence can help inform decisions on managing early-onset breast cancer linked to BRCA mutations](https://cancerworld.net/new-evidence-can-help-inform-decisions-breast-cancer-brca-mutations/) - Patients with germline BRCA gene mutations and a history of early-onset breast cancer who underwent risk-reducing bilateral mastectomy and/or a risk-reducing salpingo-oophorectomy had lower rates of death than those not undergoing these procedures. The study, presented at the 2024 San Antonio Breast Cancer Symposium (SABCS), held December 10–13, Abstract GS1-08, found that patients who underwent
- [Humour: an essential tool in cancer care and communication](https://cancerworld.net/humour-an-essential-tool-in-cancer-care-and-communication/) - “I don’t know what I’ll find in there. It could be cancer. In the best case, you’ll be stuck with a bag for the rest of your life.” Those are the words Paweł Grabowski, a fit and health-conscious 48-year-old from Warsaw, remembers hearing from his surgeon just before being wheeled in for emergency surgery for
- [Gut microbiota influence effectiveness of tamoxifen in breast cancer](https://cancerworld.net/gut-microbiota-influence-effectiveness-of-tamoxifen-in-breast-cancer/) - Variations in the microbiota of the human gut impact on the pharmacokinetics of tamoxifen in the blood and consequently on the effectiveness of breast cancer prevention. The study, published in the journal mBio, 25 November, showed that the presence of the bacteria Bacteroides fragilis in the gut is linked to the ability of β-glucuronidase enzymes
- [Young-onset digestive cancers: this is how we improve the quality of care](https://cancerworld.net/young-onset-digestive-cancers-this-is-how-we-improve-the-quality-of-care/) - “I had very severe symptoms. I had jaundice, I had itching – symptoms that could definitely indicate something related to the liver, or quite severe disease – but because of my age I was repeatedly just shoved away.” (Gabriel, eventually diagnosed aged 21 with biliary tract cancer with liver metastases) “It came as a surprise
- [Radiotherapy prior to immunotherapy is the best treatment sequence for melanoma related brain metastases](https://cancerworld.net/radiotherapy-prior-to-immunotherapy-melanoma-related-brain-metastases/) - Patients with melanoma related brain metastases achieve reduced risk of progression and better overall survival if they receive radiotherapy before immunotherapy as opposed to the other way round. The meta-analysis study, abstract RADT-04, presented at the Society of Neuro Oncology Meeting, 21–24 November, held in Houston, Texas, suggested that optimal results could be achieved when
- [Academic publishing is a maze of tests and barriers for patients as researchers and readers](https://cancerworld.net/academic-publishing-maze-for-patients/) - Once solely engaged as participants in academic studies and research, patients are increasingly becoming more involved at several stages of the research process. From helping large organisations assess grants and prioritise funding calls to participating actively in teams running research studies, ‘patient engagement’, and how to do this effectively, is a rapidly evolving topic. With
- [Stella Kyriakides: using her voice to improve health in Europe](https://cancerworld.net/stella-kyriakides-using-her-voice-to-improve-health-in-europe/) - Reproduced from The Lancet, Vol. 404, Jessamy Bagenal, Stella Kyriakides: using her voice to improve health in Europe, P1093, September 21, 2024, with permission from Elsevier. There are some politicians who get involved in health and have to reverse-engineer a narrative about their life and the choices they made to explain where they ended up. Stella
- [Florida shows cancer outcomes are better where healthcare reflects local cultures](https://cancerworld.net/florida-better-cancer-outcomes-local-cultures/) - Research conducted on cancer data for the southern US state of Florida shows how addressing sociocultural differences can bridge the gaps in cancer awareness and early detection, and improve outcomes. The study looked into the racial/ethnic disparities in stage of diagnosis of non-small-cell lung cancer, and analysed the reasons behind significant regional variations between communities
- [Study helps solve the puzzle of checkpoint inhibitor myocarditis](https://cancerworld.net/study-helps-solve-the-puzzle-of-checkpoint-inhibitor-myocarditis/) - The immune reaction that occurs in the hearts of patients taking checkpoint inhibitors who develop immune checkpoint myocarditis may be distinct from the immune responses occurring in the tumours of these patients. The study, published in in Nature, 6 November, identifies cytotoxic T cells, dendritic cells, and inflammatory fibroblasts as the likely mediators of the
- [Advocacy in oncology: Fighting for patients inside and outside the hospital](https://cancerworld.net/advocacy-in-oncology-fighting-for-patients-inside-and-outside-the-hospital/) - Dear World, Everyone can get cancer - yet, access to the right treatment remains a privilege that is still denied to far too many. In this disparity, the disease reveals a deeper truth: cancer care is not just about medicine, it's about access, affordability, and systemic inequalities that are heavily influenced by political and
- [Inequality in cancer care: preventing it from becoming inadequacy](https://cancerworld.net/inequality-in-cancer-care-preventing-it-from-becoming-inadequacy/) - “Wait! You can’t give your patients pemetrexed?” my young colleague exclaimed during a break between lectures at an international meeting. Quietly, feeling the heat rise to my cheeks, I replied, “No, it is not available in my country for that indication.” That "no" became etched in my brain, making me feel utterly defeated and sad
- [Smoking cessation fundamental to first-line cancer care](https://cancerworld.net/smokingcessation-first-line-cancer-care/) - Cancer patients who enter a smoking cessation programme within six months of receiving a diagnosis, and quit within three months after programme entry, experience a 26% reduction in mortality versus those who continue smoking. The study, published in in JAMA Oncology, October 31, found that those who quit live an average of 1.8 years longer. The
- [Assia Konsoulova: improving Bulgaria’s cancer system one oasis at a time](https://cancerworld.net/assia-konsoulova-improving-bulgarias-cancer-system/) - Assia Konsoulova in Bulgaria try to provide an ‘oasis’ of excellence, and network with like-minded practitioners on cancer care trying to build similar oases.
- [Somewhere to care for Gaza’s cancer patients: the head of the service calls for a ‘field hospital’](https://cancerworld.net/somewhere-to-care-for-gazas-cancer-patients/) - Gaza’s oncology teams are now calling for a ‘cancer field hospital’ where they can provide the diagnostics, treatment and care that their patients need.
- [Lessons in nature: knowledge of exceptional animals could help tackle human cancers](https://cancerworld.net/lessons-in-nature-knowledge-animals-human-cancers/) - Cancer prevalence across vertebrate species increases with higher adult mass and decreases with longer gestation periods. The study, published in Cancer Discovery, October 24, has identified more than 90 different species of animals (including the common dolphin, common porpoise and Rodrigues fruit bat) that appear to be highly resistant to developing cancer. “If you look
- [Breast cancer treatments may accelerate ageing](https://cancerworld.net/breast-cancer-treatments-may-accelerate-ageing/) - Breast cancer treatments activate genes associated with biological ageing. The study, published in the Journal of the National Cancer Institute, 8 October, suggests that chemotherapy, radiation, and surgery all lead to statistically significant increases in cellular senescence and DNA damage response genes. “While we expected to see increased gene expression linked to biological aging in
- [Surgery or radiotherapy? How the pandemic provide an opening to gather the evidence that patients need](https://cancerworld.net/surgery-or-radiotherapy/) - In cancers treated by either surgery or radiotherapy, barriers to testing leaves patients unable to make informed choices: why it is so hard to do trials?
- [‘I feel guilty sometimes’: a young carer reflects on three years of a losing battle to save his mum](https://cancerworld.net/i-feel-guilty-sometimes-a-young-carer-reflects/) - Mohit Singh, the caregiver for his mother Amrita, describes the long and unsuccessful journey they took together to get cancer medical help across India.
- [Targeting a circulating cytokine offers new hope in cancer cachexia](https://cancerworld.net/targeting-a-circulating-cytokine-offers-new-hope-in-cancer-cachexia/) - Among patients with cancer cachexia and elevated levels of the cytokine GDF-15, inhibiting GDF-15 with ponsegromab resulted in increased weight gain. The study, published in the New England Journal of Medicine, 14 September, showed that in comparison to placebo, patients taking ponsegromab had reduced cachexia symptoms and improvements in appetite, overall physical activity, and skeletal muscle mass.
- [Nobel Prize for medicine awarded for discovery of microRNAs, which play key role in cancer development](https://cancerworld.net/nobel-prize-medicine-micrornas-key-role-cancer-development/) - The 2024 Nobel Prize in Physiology or Medicine, announced on Monday 7 October, has been awarded jointly to Victor Ambros and Gary Ruvkun for discovering microRNAs and their role in post-transcriptional gene regulation. The work by Ambros, now at the University of Massachusetts Medical School, and Ruvkun, now at Harvard Medical School, helps explain how
- [Voices from Gaza: caught between conflict and cancer](https://cancerworld.net/voices-from-gaza-caught-between-conflict-and-cancer/) - In every conflict, it is the most vulnerable who suffer the most. The great majority of Gaza’s population of two million now live in terrible conditions, with poor sanitation, limited access to clean water, infectious diseases rife and precarious access to nutrition – fresh fruit and vegetables in particular. Many live in overcrowded encampments, or
- [Improving outcomes in poor-prognosis cancers: novel approaches and strategic challenges](https://cancerworld.net/improving-outcomes-in-poor-prognosis-cancers/) - Recent decades have seen major advances in how we treat cancer, leading to significant improvements in survival rates. For example, women who are diagnosed with early-stage breast cancer today are 66% less likely to die from the disease within five years of diagnosis than they were 20 years ago. But this isn’t the case for all
- [Study opens way for using antifibrotic drugs to prevent metastasis](https://cancerworld.net/study-opens-way-antifibrotic-drugs-prevent-metastasis/) - Adding a drug currently used against idiopathic pulmonary fibrosis to chemotherapy in the neoadjuvant setting increased event-free survival in patients with early HER2-negative breast cancer. The study, published in Clinical Cancer Research, 16 September, found that high levels of fibrosis in the microenvironment predicted poor outcomes, and that those poorer outcomes could be corrected by
- [ESMO launches initiative to tackle burnout in oncology healthcare professionals](https://cancerworld.net/esmo-launches-initiative-burnout-oncology-professionals/) - The European Society for Medical Oncology (ESMO) is calling on the oncology community to commit to improving the wellbeing of the cancer workforce. In a paper published in ESMO Open, 10 September, ESMO outlines 11 actions to manage psychosocial risks, optimise wellbeing and reduce burnout, and provides evidence-based plans to address growing pressures. “Too many
- [Why is the cancer mortality gap between Eastern and Western Europe so hard to close? ](https://cancerworld.net/why-is-the-cancer-mortality-gap-eastern-western-europe-hard-to-close/) - Efforts to reduce the excess risk of dying from cancer faced by people living in countries of Eastern and Central Europe, compared with their Western counterparts have been high on the European agenda for the best part of two decades. In 2005 a group of European Parliamentarians launched MEPs Against Cancer, to promote policy initiatives
- [Antibody-drug conjugate proves effective against active brain metastases](https://cancerworld.net/antibody-drug-brain-metastases/) - The antibody drug conjugate trastuzumab deruxtecan (T-DXd) showed substantial intracranial activity in patients with HER2-positive breast cancer whose disease had metastasised to the brain. The DESTINY-Breast12 study, presented at the Congress of the European Society for Medical Oncology (ESMO), held 13–17 September in Barcelona, (Abstract LBA18), and published simultaneously online in Nature Medicine, showed that
- [Can a novel anti-diabetic, anti-obesity ‘wonder drug’ be repurposed for cancer?](https://cancerworld.net/can-a-novel-anti-diabetic-drug-repurposed-cancer/) - Throughout human history, the search for a universal cure has captivated the minds of philosophers, healers and scientists across time and cultures. In Greek mythology, the goddess Panacea was believed to possess a potion to treat all afflictions. We still use the term ‘panacea’ to refer to a single remedy that can solve all problems.
- [Women, power and cancer in India](https://cancerworld.net/women-power-and-cancer-in-india/) - There is not a dull moment when Tulasi Singh is around. She makes sure that the women’s hall on the fifth floor of the Gadge Maharaj Dharamshala, a subsidised hostel for cancer patients close to the Tata Memorial Hospital in Mumbai, India, is filled with laughter and chatter. Tulasi, who is pictured above, getting ready
- [Safely pausing or stopping treatment: could this be the future for solid tumours?](https://cancerworld.net/safely-pausing-or-stopping-treatment-solid-tumours/) - The success of treatment cessation in chronic myeloid leukaemia (CML), outlined in an earlier Cancerworld feature, is opening the way for treatment breaks – or cessation with monitoring – to be considered in advanced solid tumours, including breast, kidney, colorectal, and prostate cancers. In kidney, prostate and colorectal, the focus is on patients taking treatment
- [Early menopause raises own risk of breast cancer and family members' risk of breast, colon and prostate cancers](https://cancerworld.net/early-menopause-risk-breast-cancer-family-members-breast-colon-and-prostate-cancers/) - Women who experience primary ovarian insufficiency (menopause before the age of 40) are more than twice as likely to experience breast cancer as other women of similar ages. The study, published in the Journal of Clinical Endocrinology and Metabolism, 12 July, also showed that in second-degree relatives (grandparents, aunts/uncles, nieces/nephews, half-siblings, and grandchildren), the risk
- [Raised suicide risk highlights need to support patient’s spouse](https://cancerworld.net/raised-suicide-risk-support-patients-spouse/) - The spouses of patients diagnosed with cancer were 28% more likely to attempt suicide and 47% more likely to succeed at their attempt than spouses of people not diagnosed. The Danish cohort study, published in Jama Oncology, August 15, found that the risk was especially high during the first year after the diagnosis, when the
- [Manfred Wirth: a tribute to a pioneer of urological advancement in Europe](https://cancerworld.net/manfred-wirth-a-tribute-to-a-pioneer-of-urological-advancement-in-europe/) - Cancerworld mourns the loss of Professor Manfred Wirth, a leading light in European urology. His remarkable contributions to the field earned him the esteemed Willy Gregoir Medal, marking him as a true pioneer. We share here the tribute from the European Association of Urology, where Professor Wirth served for many years as an Executive Member
- [Drug repurposing: EU legislative changes could speed up new treatment options](https://cancerworld.net/drug-repurposing-eu-legislative-changes-speed-up/) - The length of time it takes for each new cancer drug to reach the market – and more importantly, the patient – remains a cause of deep frustration particularly among those whose lives depend on accessing new options. Concrete data is hard to come by, but estimates of the time taken to complete clinical trials
- [Keeping family hopes alive among  African women treated for breast cancer](https://cancerworld.net/keeping-family-african-women-breast-cancer/) - In Africa, women's infertility carries a heavy stigma; it becomes their label. Many end up feeling worthless, face harsh treatment from in-laws, abandonment by spouses, or relegation to polygamous marriages, as husbands take additional wives capable of bearing children. For Linet Auma, a 27-year-old recently diagnosed with HER2-positive breast cancer, the fear of losing her
- [Aspirin prevents colorectal cancer best in those with least healthy lifestyles](https://cancerworld.net/aspirin-prevents-colorectal-cancer-healthy-lifestyles/) - Regular aspirin may help lower risk of colorectal cancer most effectively in people who have greater lifestyle-related risk factors for the disease. The study, published in JAMA Oncology on 1 August, found that, to prevent one case of colorectal cancer over 10 years, 78 people would need to be treated in the least healthy group
- [Endometriosis: impact on ovarian cancer varies by subtype](https://cancerworld.net/endometriosis-impact-ovarian-cancer-by-subtype/) - Women with endometriosis have a fourfold higher risk of any type of ovarian cancer and those with severe endometriosis a 10 fold higher risk compared to women who do not have the condition. The study, which involved a cohort of nearly 80,000 women with endometriosis, and was published in Journal of the American Medical Association,
- [Soft policies on smokeless tobacco to cost India, Pakistan and Bangladesh billions](https://cancerworld.net/soft-policies-on-smokeless-tobacco-india-pakistan-bangladesh/) - Smokeless tobacco products such as paan masala, gutkha, khaini, mishri and snuff are chewed, sucked or sniffed rather than smoked, with the nicotine absorbed through the nose and mouth. Many contain more than 4,000 chemicals, 30 of which are linked to cancer. There is a common misconception in South Asian countries that these are less harmful than
- [From social determinants to cancer outcomes: the cell biology behind the disparities](https://cancerworld.net/from-social-determinants-to-cancer-outcomes/) - This article is from 2022, if you are interested in this topic you can also read: From social determinants to cancer outcomes: the cell biology behind the disparities Raised levels of stress are a normal response to being diagnosed with cancer, and asking patients about their psychological and emotional wellbeing is, or should be, a
- [Disadvantaged neighbourhoods may contribute to racial disparities in risk of aggressive prostate cancer](https://cancerworld.net/disadvantaged-neighbourhoods-risk-of-aggressive-prostate-cancer/) - Men with prostate cancer living in disadvantaged neighbourhoods show significantly higher activity of stress-related genes than those living in other neighbourhoods. The observational study, published in JAMA Network Open, 12 July, found that neighbourhood disadvantage was positively associated with the expression of a number of stress-related genes, some of which are proinflammatory and could contribute
- [Exercise boosts anti-tumour immune cells in people with breast cancer](https://cancerworld.net/exercise-boosts-anti-tumour-immune-cells-breast-cancer/) - Just 30 minutes of exercise increases the proportion of tumour-killing immune cells in the blood of people with breast cancer. The Finnish study, published in Frontiers in Immunology, 24 June, found that the proportion of CD8+ T cells and natural killer (NK) cells increased and the proportion of myeloid derived suppressor cells (MDSCs) decreased. “Our
- [Is yours a beach-ready body? Dietary tips to lower your risk of melanoma](https://cancerworld.net/is-yours-a-beach-ready-body-dietary-tips-to-lower-your-risk-of-melanoma/) - “Did you remember to bring the sunscreen?” Public awareness of the need to protect against the risk of melanoma from excessive exposure to UV rays from the sun has risen dramatically over recent decades. ‘Bringing the sunscreen’ is now a normal part of heading off to an outdoor activity or away on holiday, and we’ve
- [Treatment-free remission: How today’s CML patients can aspire to a drug-free life](https://cancerworld.net/treatment-free-remission-cml-patients/) - Around the start of the millennium, the therapeutic landscape for chronic myeloid leukaemia (CML), a rare type of blood cancer affecting the bone marrow and white blood cells, was transformed by the arrival of a revolutionary cancer drug. This was imatinib (Glivec), the first of the rationally designed, small-molecule tyrosine kinase inhibitors (TKIs) that have
- [Quality palliative care: investing in data collection to monitor and improve services in Africa](https://cancerworld.net/quality-palliative-care-investing-in-data-collection/) - Effective palliative care has become a growing priority in African health services in recent decades. This is partly a result of the increasing burden of non-communicable diseases including cancer – and the sad reality that palliative care is often all that can be offered by way of cancer care, because the diagnosis often comes too
- [Liver biopsies can predict when and where pancreatic cancer will metastasise and may guide treatment of early-stage disease](https://cancerworld.net/liver-biopsies-can-predict-pancreatic-metastasise/) - Liver biopsies undertaken at the time of surgery for pancreatic cancer can be used to identify cellular and molecular markers that predict whether early pancreatic cancer will later metastasise to the liver. The study, published in Nature Medicine, June 28, showed that a machine-learning model, trained on information obtained from the biopsies, can predict metastatic
- [Common blood pressure drug could be used in AML to cut cardiotoxicity and improve response to chemotherapy](https://cancerworld.net/common-blood-pressure-improve-response-chemotherapy/) - Treating acute myeloid leukaemia with losartan, a commonly used blood pressure agent, achieved the dual benefits of enhancing chemotherapy efficacy and preventing cardiotoxicity in a mouse model. The study, published in Science Translational Medicine, 19 June, demonstrated both benefits were achieved through blockade of the well-known cardiovascular disease target, angiotensin II receptor type 1 (AGTR1).
- [Precision medicine for all!](https://cancerworld.net/precision-medicine-for-all/) - Every year, around 2.3 million people across the globe are diagnosed with breast cancer. For lack of access to the right diagnostic test, many of them are being treated with chemotherapy that is doing them more harm than good – often having to make difficult journeys and pay bills they can ill afford, for the
- [If the risk is very low, should we still call it ‘cancer’?](https://cancerworld.net/if-the-risk-is-very-low-call-it-cancer/) - 'Cancer’ is the weightiest of words. Jacky remembers the impact those two short syllables had when she was given her results after tests for breast cancer. “I went into this little room and they told me that I had cancer in situ. Now the only word I heard was cancer, and I thought, what are
- [Neoadjuvant immunotherapy delivers unprecedented pathological response in mismatch repair deficient non-metastatic colon cancers](https://cancerworld.net/neoadjuvant-immunotherapy-unprecedented-pathological-response/) - In patients with non-metastatic colon cancer who have mismatch repair deficient tumours, a short course of neoadjuvant immunotherapy (one cycle ipilimumab and two cycles nivolumab) was highly effective. The NICHE-2 trial, published in the New England Journal of Medicine, June 5, showed that the immunotherapy regimen had an acceptable safety profile, with 95% of patients
- [Generation X will experience higher rates of cancer than earlier generations](https://cancerworld.net/generation-x-higher-rates-of-cancer/) - At age 60 members of Generation X, defined as people born between 1965 and 1980, are projected to have higher rates of cancer than Baby Boomers, born between 1946 and 1964. The US modelling study, published online in JAMA OpenNetwork, 10 June, revealed that, among Generation X men, declines in lung, liver, and gallbladder cancers
- [How telomeres protect our chromosomes, and what happens when they don’t](https://cancerworld.net/how-telomeres-protect-our-chromosomes/) - Chromosomes are essential structures in the nucleus of eukaryotic cells that carry genetic information as DNA. DNA is organised into genes, which provide the instructions for building and maintaining the organism. During cell division, chromosomes ensure that each daughter cell receives an accurate and complete set of genetic information. Specialised structures, called telomeres, protect the
- [Craig Jordan: father of tamoxifen, discoverer of SERMs, legend in his own time 1947-2024](https://cancerworld.net/craig-jordan-father-of-tamoxifen-discoverer-of-serms-legend-in-his-own-time-1947-2024/) - The extraordinary career of Virgil Craig Jordan, Dallas/Fort Worth Living Legend Chair of Cancer Research, one of the ‘Four for the Millennium’ in women’s health, Order of the British Empire, Companion of the Most Distinguished Order of St. Michael and St. George, and so very much more, has come to an end. He will be
- [Giuseppe Curigliano: driving progress in precision cancer medicine](https://cancerworld.net/giuseppe-curigliano-driving-progress-in-precision-cancer-medicine/) - “Fundamentally, if you do more whole genome sequencing, you’ll discover more targetable alterations, and once you have this information you can consider whether there are any clinical trials available for your patient.” The advice comes from Giuseppe Curigliano, Head of the Clinical Division of Early Drug Development at Milan’s European Institute of Oncology, and Professor
- [Tailoring palliative care visits to patients’ needs saves resources without harm](https://cancerworld.net/tailoring-palliative-care-visits-to-patients/) - Stepped palliative care, with visits occurring only at key points in the patient’s cancer journey, resulted in fewer palliative care visits than conventional early palliative care. The study, presented at the American Society of Clinical Oncology (ASCO) meeting, held May 31 to June 4, in Chicago, and published simultaneously online in the Journal of the
- [Cancer treatment or future parenthood? Poland’s patients are finally spared that choice](https://cancerworld.net/cancer-treatment-or-future-parenthood-polands/) - Efforts to ensure that cancer patients can have children after treatment have been hampered in Poland by the lack of a national fertility service. The costs of fertility preservation – greater than the average Polish salary – have normally had to be paid out of patients’ own pockets, making it unaffordable to most. At least,
- [Using telemedicine in cancer care for environmental and public health benefit](https://cancerworld.net/using-telemedicine-in-cancer-care-public-health-benefit/) - Telemedicine, in addition to patient convenience, offers the environmental benefit of reducing greenhouse gas emissions, with knock-on benefits for people with chronic conditions. The study, presented at the annual meeting of the American Society of Clinical Oncology (ASCO), held May 31 to June 4, and published simultaneously in JAMA Oncology, suggests that delivering cancer care
- [Patients in Turkey sue for reimbursement as the price of cancer drugs escalates](https://cancerworld.net/patients-in-turkey-sue-reimbursement-price-cancer-drugs/) - The cost of cancer drugs in Turkey has escalated in recent months, putting some key drugs beyond the reach of most people. Legal routes to secure reimbursement are having some success, but that route is only available to some people, and it is adding delays, costs and stress, as Marwa Koçak reports. An acute financial
- [AI in oncology: revolutionising care while mitigating inequities](https://cancerworld.net/ai-in-oncology-revolutionising-care-while-mitigating-inequities/) - During a recent clinic visit, a young woman newly diagnosed with breast cancer mentioned that she had used ChatGPT to research treatment options. We explained to the patient that, although ChatGPT can give sophisticated responses in an authoritative tone, it is not entirely reliable in generating medical recommendations, mainly because its knowledge is limited to
- [Artificial Intelligence: Capturing the zeitgeist](https://cancerworld.net/artificial-intelligence-capturing-the-zeitgeist/) - As the Austrian writer Karl Kraus pointed out at the turn of the twentieth century, the development of technology will leave only one problem: the infirmity of human nature. That ‘remaining problem’ was the focus of an article published last December, in which pioneering AI scientist Fei-Fei Li was asked about the significance of the
- [HPV vaccination programme will reduce cervical cancer health inequalities](https://cancerworld.net/hpv-vaccination-programme-reduce-inequalities/) - England's HPV vaccination programme is helping to close inequalities in cervical cancer, cutting incidence rates across the socioeconomic spectrum. The study, published in the BMJ, found that the vaccination programme was associated with a substantially reduced incidence of cervical cancer and grade 3 cervical intraepithelial neoplasia across every level of socioeconomic deprivation. “Historically, cervical cancer
- [India’s HPV vaccine: another step towards eradicating cervical cancer](https://cancerworld.net/indias-hpv-vaccine-eradicating-cervical-cancer/) - It’s hard to remember that, at the time it was introduced in 2008, many questions were raised about whether the human papillomavirus (HPV) vaccine would be cost effective. In the intervening decade and a half, it has become abundantly clear that it is. A 2021 UK study showed that it has reduced cervical cancer rates
- [Use of e-cigarettes after quitting smoking increases lung cancer risk](https://cancerworld.net/use-of-e-cigarettes-lung-cancer-risk/) - Former cigarette smokers who use electronic cigarettes may be at higher risk of lung cancer than those who do not use these devices. The study abstract 3051, presented in a session at the American Thoracic Society 2024 International meeting, held in San Diego, California, May 17–22, found that ex-smokers who had quit for less than
- [Moldovan cancer services get an upgrade as they welcome patients from Ukraine](https://cancerworld.net/moldovan-cancer-services-upgrade-ukraine/) - Since Russia’s full-scale invasion of Ukraine in February 2022, Moldova has been a key destination for refugees because of its geographical proximity and cultural similarities to Ukraine. Over one million Ukrainian refugees have passed through Moldova and 100,000 are currently staying there. For a country with a population of 2.6 million and limited resources for medical
- [The Kenyan clinical research unit bringing precision cancer medicine to East Africa](https://cancerworld.net/the-kenyan-clinical-precision-cancer-medicine-east-africa/) - Four years ago, clinical trials were little discussed in oncology circles in Kenya. In common with the rest of East Africa, there was no clinical research unit to study treatments for non-communicable diseases such as cancer. No cancer patient living in Kenya had ever been offered experimental therapies as part of a trial in their
- [Cancer survivors who are less lonely live longer](https://cancerworld.net/cancer-survivors-less-lonely-live-longer/) - Greater feelings of loneliness are associated with higher mortality rates among cancer survivors. The study, published in the Journal of the National Comprehensive Cancer Network (JNCCN), April 25, found that cancer patients reporting severe loneliness had a 67% higher all-cause mortality rate than those reporting low/no loneliness. “Programs to screen for loneliness among cancer survivors
- [Plant-based diets lower risk of progression in prostate cancer](https://cancerworld.net/plant-based-diets-lower-risk-prostate-cancer/) - Higher intakes of plant foods following a diagnosis of prostate cancer were associated with lower risks of cancer progression. The study, published in JAMA Netw Open, 1 May, found men diagnosed with early prostate cancer whose plant food intake was in the highest quintile (20%) had 47% lower risk of progression than those in the
- [Prevention messages: negotiating the tricky interface between medicine and popular culture](https://cancerworld.net/cancer-prevention-negotiating-the-tricky/) - “Cigarettes are shit.” The slogan is neither creative nor informative, yet it had an impact beyond all expectations in Poland in 1994. These were the early days of post-communism: tobacco companies were making the most of the opportunities of the free market, but people were feeling the rebellious power of the street. The slogan appeared
- [Extracellular vesicles from injured hearts accelerate tumour growth](https://cancerworld.net/extracellular-vesicles-from-injured-hearts/) - Small extracellular vesicles secreted by the hearts of mice with myocardial infarction accelerated the growth of lung cancer tumours already present in the same mice. The study, published online in Circulation, 15 March, found that the cardiovascular drug spironolactone reduced both the number of vesicles produced and resulting tumour growth. “We showed for the first
- [In a remote corner of India, a cancer centre is showing what can be achieved with technology and compassion](https://cancerworld.net/in-a-remote-corner-of-india-cancer-centre/) - In a remote, inaccessible and hilly area of the north-east Indian state of Assam, local residents of the Cachar district came together twenty years ago to form the Cachar Cancer Society for cancer prevention, detection and treatment. They felt a cancer centre was desperately needed in their region, as the nearest centre was in Assam’s
- [One-stop lung screening and smoking cessation advice works](https://cancerworld.net/one-stop-lung-screening-and-smoking-cessation/) - Offering ‘stop smoking’ support as part of a national lung cancer screening programme resulted in nearly nine out of ten people agreeing to an immediate consultation and three-quarters accepting longer term support. The evaluation of an ‘opt-out’ face-to-face smoking cessation service located at a community based mobile screening unit, published in The European Respiratory Journal,
- [Quality care, free of charge, and closer to home: expanding access to cancer services in India](https://cancerworld.net/quality-care-free-of-charge-and-closer-to-home-expanding-access-to-cancer-services-in-india/) - If you are interested in cancer care in low and middle income countries we also suggest: Africa Regional cancer centres to boost access to cancer care across Uganda Not just a climate issue: cutting cancer rates through cleaner cooking fuels in Africa Cancer drugs for Africa… from Africa? Asia Pooled procurement of drugs saves millions
- [PSA population screening is back in favour: here’s why](https://cancerworld.net/psa-population-screening-is-back-in-favour-heres-why/) - Today clinicians and advocates are campaigning for population PSA screening for prostate cancer programmes across Europe despite troubles that occurred 20 years ago.
- [A success story in Romania’s struggle to control cervical cancer](https://cancerworld.net/success-story-romanias-control-cervical-cancer/) - A GP in one small rural community is showing what can be achieved with (HPV) vaccinations if you take the time to explain things well and build trust.
- [HPV vaccination set to be rolled out across Turkey… with controversial exclusions](https://cancerworld.net/hpv-vaccination-set-to-be-rolled-out-across-turkey-with-controversial-exclusions/) - Turkey is set to roll out a national HPV vaccination programme: the decision to deny reimbursed access to unmarried women is being challenged in the courts.
- [Delivering cervical cancer screening across India: the plan… and the practice](https://cancerworld.net/delivering-cervical-cancer-screening-across-india-the-plan-and-the-practice/) - In 2016, India issued the first guidelines on screening programmes for cervical, breast and oral cancers, which all 28 states must now roll out: how's going?
- [Regular symptom reporting can help your patients live better, and possibly longer](https://cancerworld.net/regular-symptom-reporting-patients-live-better-longer/) - An older woman receiving treatment for breast cancer sits at home wondering whether to call her physician and go into the hospital. She’s on a new dose of a drug which she hasn’t had before and is struggling with nausea. Not unusual for a person with cancer on treatment, but it’s been days now and
- [Women make great surgeons, so why is the profession still dominated by men?](https://cancerworld.net/women-make-great-surgeons-so-why-is-the-profession-still-dominated-by-men/) - Women have broken into the surgical profession over the past 50 years and proved their value. Yet they remain significantly underrepresented.
- [On being a woman in oncology: in their own words](https://cancerworld.net/on-being-a-woman-in-oncology-in-their-own-words/) - This article is from 2022, if you want to read other things on the same topic we recommend: Women’s career progression in science: challenges, barriers, and solutions Unpaid women carers: recognising their contribution and their needs in Latin America A fair chance for women in oncology: we must all insist on change Over the past
- [New drug combination offers potential to prevent bone metastasis](https://cancerworld.net/new-drug-combination-prevent-bone-metastasis/) - A combination of existing drugs may inhibit development of bone metastasis in breast cancer patients. The study published in Cancer Discovery, 1 March, found that a combined treatment strategy that activates T cells while at the same time targeting cells inhibiting T cells could prevent metastases from breast cancer forming in the bones. “Our study
- [Slowing ‘accelerated ageing’ may offer new avenue for cancer prevention](https://cancerworld.net/slowing-accelerated-ageing-cancer-prevention/) - Accelerated ageing is more common in recent birth cohorts and associated with increased incidence of early-onset solid tumours. The study, abstract 846, presented at the American Association for Cancer Research (AACR) Annual Meeting, held April 5–10, in San Diego, found that each standard deviation increase in accelerated ageing – defined according to a set of
- [New prostate cancer blood test combining PSA with epigenetic test could reduce biopsies](https://cancerworld.net/new-prostate-cancer-blood-test-psa-epigenetic/) - A non-invasive prostate cancer combination test has been shown that out of 100 patients testing positive for prostate cancer 93 will truly have the condition.
- [Hello again! Beautiful, feminine, sexy post-mastectomy me!](https://cancerworld.net/hello-again-beautiful-feminine-sexy-post-mastectomy-me/) - It all started with a high school friendship. Anna Szołucha, a photographer who specialises in noir-style black-and-white female nudes, read a post by her high school friend Agnieszka Ford on social media. Agnieszka wrote that she was in a medical consultation for breast reconstruction. “It was an impulse,” recalls Szołucha. “I wrote to her and
- [EBCC manifesto urges action to overcome disparities in metastatic breast cancer](https://cancerworld.net/manifesto-disparities-metastatic-breast-cancer/) - All patients with metastatic breast cancer should have equal access to the best treatments and outcomes regardless of where they live in Europe. The EBCC14 manifesto, agreed at the 14th European Breast Cancer Conference (EBCC) on March 22 in Milan, considered recommendations to address metastatic breast cancer issues around stigma, registries and real-world data, multidisciplinary
- [Secondhand smoke reduces cisplatin impact on head & neck tumour cells](https://cancerworld.net/secondhand-smoke-reduces-cisplatin-impact-on-tumour-cells/) - Secondhand smoke significantly reduced the ability of chemotherapy to kill head and neck cancer cells and increased the cells’ ability to reproduce. The study, published in the International Journal of Molecular Sciences, found that secondhand smoke altered the proteins that carry cisplatin into cancer cells. “These findings emphasise the urgent need for clinicians to consider
- [Tackling cancer in high-risk areas: the ‘Marmot City’ model](https://cancerworld.net/tackling-cancer-in-high-risk-areas-the-marmot-city-model/) - Inequalities in social, economic and educational status are inherent in all societies, to a greater or lesser extent. The discovery that a person’s health and life expectancy are closely tied to their position in the social hierarchy opened up new opportunities to improve public health by addressing the inequalities, and specifically the factors that link
- [Por fin! A cancer prevention code for Latin America and the Caribbean](https://cancerworld.net/por-fin-a-cancer-prevention-code-for-latin-america-and-the-caribbean/) - Last October, the Pan American Health Organization (PAHO) launched its Latin American and Caribbean Code Against Cancer, seeking to help reduce the region’s rising cancer incidence rates. “We must act now to reverse the projected trends,” said Elisabete Weiderpass, Director of the World Health Organization’s International Agency for Research on Cancer (IARC). The trends are
- [Cancer Grand Challenge projects to shine light on unanswered oncology questions](https://cancerworld.net/cancer-grand-challenge-projects/) - The Cancer Grand Challenges initiative has announced the five global research teams who between them will receive $125 million to address unanswered questions. The winning teams, revealed in March, are addressing four major oncology challenges – solid tumours in children, T-cell receptors, early onset cancers, and cancer inequalities. “Some of these challenge areas have been
- [Childhood cancer survivors need younger monitoring for cardiovascular disease](https://cancerworld.net/childhood-cancer-survivors-cardiovascular-disease/) - Survivors of childhood cancer are at a significantly higher risk of death following a major cardiovascular event than the general public. The study, published in the Journal of the American College of Cardiology 27 February, found risk of death after a major cardiovascular event in a 30-year-old who had previously been treated for cancer as
- [The voice of the older adult: how to make it count in decisions about their care](https://cancerworld.net/the-voice-of-the-older-adult/) - Involving patients as equal partners in choosing between treatment options is particularly important when there is considerable uncertainty about how the options could affect their survival and quality of life. Such is often the case in treating older patients, who tend to be more frail and have more comorbid health problems than the highly selective
- [Mechanisms linking chronic stress to raised metastasis risk discovered](https://cancerworld.net/mechanisms-linking-stress-to-metastasis/) - Stress causes neutrophils to form sticky ‘web-like structures’, making body tissues more susceptible to cancer metastasis. The study published in Cancer Cell, 22 February, demonstrated that the stress hormone glucocorticoid leads to the formation of neutrophil extracellular traps (NETs), known to drive metastasis-promoting microenvironments. “What’s novel and exciting about our study is that we have
- [Women's career progression in science: challenges, barriers, and solutions](https://cancerworld.net/womens-career-progression-in-science/) - Despite significant and hopefully promising discussions, graphs plotted using data from studies conducted at global and European levels continue to show a distinctive ‘scissors’ shape, indicating a significant gender gap in academic and scientific careers, which starts at the doctoral level, and widens from there on. In recent decades, the proportion of women among undergraduates
- [Older adults with advanced cancers may do better on modified regimens](https://cancerworld.net/older-adults-advanced-cancers-modified-regimens/) - Lowering the dose and adjusting the schedule may help older adults with advanced cancer better tolerate chemotherapy. The cohort study, published in JAMA Network Open, February 15, found older patients with advanced cancer who underwent primary treatment modification had a 15% reduced risk of serious clinician-rated toxic effects and a 20% reduced risk of patient-reported
- [Making sense of recent progress in advanced breast cancer](https://cancerworld.net/making-sense-of-recent-progress-in-advanced-breast-cancer/) - Every two years breast cancer specialists and patient advocates gather at the Advanced Breast Cancer (ABC) International Consensus Conference to discuss challenges and uncertainties in treatment and care of people with advanced breast cancer, to explore how evidence, knowledge and understanding has changed since the previous conference, and to update the international consensus ABC guidelines.
- [Integrative and complementary cancer care mends an ancient division to put patients first](https://cancerworld.net/integrative-and-complementary-cancer-care/) - Physicians and cancer services provide better care when they recognise the benefit that complementary therapies can bring to their patients’ mental and physical wellbeing – as well as the potential risks. Complementary and Alternative Medicine (CAM) is defined by the WHO as “a broad set of health care practices that are not part of that
- [Ethnic differences in cancer biology: What we are learning, and why it matters](https://cancerworld.net/ethnic-differences-cancer-biology/) - There have been great strides in our understanding of cancer genomics - the mutational events that lead to high cancer risks and those that drive progression in cancer patients. Using vast databases such The Cancer Genome Atlas (TCGA) from the United States, which has molecularly characterised over 20,000 primary cancer and matched normal samples, in
- [Alejo Albornoz: A bridge between two cancer realities in Argentina](https://cancerworld.net/alejo-albornoz/) - The move didn’t make any sense. Any young clinical oncologist trying to climb up the career ladder in Argentina knows that Buenos Aires is the place to be. So, when in 2021 Alejo Albornoz, then 33, moved with his partner and four dogs from their home in the capital city to the provincial town of
- [Financial vulnerability linked to late cancer diagnosis](https://cancerworld.net/financial-vulnerability-cancer-diagnosis/) - Patients with major ‘adverse financial events’ – bankruptcies, liens (losing ownership of property pending payment of debt), or evictions – are more likely to have cancer diagnosed at an advanced stage than those without such serious financial problems. The US study, published in the Journal of Clinical Oncology, February 6, found that one-third of newly
- [Increasing cardiorespiratory fitness reduces risk of prostate cancer](https://cancerworld.net/increasing-cardiorespiratory-fitness-reduces-risk-prostate-cancer/) - Increasing cardiorespiratory fitness rates by an average 3% a year or more is linked to a 35% reduced risk of men developing prostate cancer in comparison to those whose fitness levels declined by 3% over the same time period. The Swedish study, published in the British Journal of Sports Medicine, February 1, did not find
- [John Ryan: a true public health champion](https://cancerworld.net/john-ryan-a-true-public-health-champion/) - Europe’s public health and cancer communities have been paying tribute to John Ryan, former Deputy Director General of European Commission Health Directorate, following his untimely death at the age of 65. Ryan had only recently retired, after spending decades helping shape and expand European health policy to the point we have reached today, with the
- [Hero? Survivor? Using the right words matters, but it’s not always straightforward](https://cancerworld.net/hero-survivor-using-the-right-words-matters-but-its-not-always-straightforward/) - A new survey of 1,871 people living with cancer in the UK and US has revealed significant differences in the terms that they would like to be used to describe themselves. Descriptive terms such as “victim,” “sufferer” and “cancer stricken” were considered to be overwhelmingly negative, whereas terms such as “warrior”, “hero”, “thriver” and “on
- [Drop in metastatic breast cancer mortality ‘greater than expected’](https://cancerworld.net/drop-metastatic-breast-cancer-mortality/) - Between 1975 and 2019 breast cancer deaths dropped by 58% due to a combination of screening mammography and improved treatment. The US modelling study published in JAMA, 16th January 2024, found that by 2019 nearly one third of the decrease could be attributed to advances in treating metastatic breast cancer. “What really surprised us was
- [Not just a climate issue: cutting cancer rates through cleaner cooking fuels in Africa](https://cancerworld.net/not-just-a-climate-issue-cutting-cancer-cooking-fuels-in-africa/) - Nearly one billion people in Africa depend on polluting fuels like wood, charcoal, and kerosene for cooking, lighting, and heating their homes. The resulting household air pollution leads to approximately 700,000 premature deaths every year, constituting about 10% of the continent's total mortality. In Kenya alone, an estimated 23,000 lives are lost annually due to
- [Lynch syndrome patients show poor aspirin adherence](https://cancerworld.net/lynch-syndrome-poor-aspirin-adherence/) - Only around one third of people with Lynch syndrome, the most common form of hereditary colorectal cancer, report taking aspirin as chemopreventive therapy. The survey, abstract 19, presented at the 2024 ASCO Gastrointestinal Cancers Symposium, held January 18–20, in San Francisco, found poor uptake was associated with perceptions of inconvenience, side effects and low preventive
- [Pooled procurement of drugs saves millions for Indian cancer centres](https://cancerworld.net/pooled-procurement-of-drugs-saves-millions-for-indian-cancer-centres/) - A pilot project pooling the procurement of cancer drugs has led to cancer institutes in India saving over USS 116 million – an 82% average reduction on the drugs' reference prices. The results of the pilot project, led by Tata Memorial Hospital in Mumbai and published in the Bulletin of World Health Organisation, show how
- [Reversing the rising trend in prostate cancer mortality in Poland](https://cancerworld.net/reversing-the-rise-in-prostate-cancer-mortality-in-poland/) - Between 2015 and 2020, age-standardised prostate cancer mortality rates rose by an estimated 18% in Poland, reflecting an increase in deaths from 4,876 to 5,748 over that period. This trend was in sharp contrast to EU countries as a whole, where prostate cancer mortality rates fell by an estimated 7.1% during that time. This worrying
- [Rise in initiation of immunotherapy at the end of life](https://cancerworld.net/rise-in-initiation-of-immunotherapy-at-the-end-of-life/) - Immunotherapy is increasingly being initiated in the month prior to death in patients with stage IV non-small-cell lung cancer, melanoma, and renal cell carcinoma. The US study, published in JAMA Oncology, online January 4, showed the practice was more common at nonacademic and lower-volume health care centres than academic centres, and that nonacademic and lower
- [Flaxseed could provide protection against breast cancer](https://cancerworld.net/flaxseed-protection-breast-cancer/) - Components of flaxseed may help to prevent the development of breast cancer. The mouse study, published in Microbiology Spectrum, 7 December 2023, uncovers a novel link between flaxseed consumption in the diet, the gut microbiota and microRNAs in the breast responsible for regulating expression of genes related to breast cancer. “We found that flaxseed alters
- [From stigma to strategy: Egypt's journey in combating cervical cancer](https://cancerworld.net/from-stigma-to-strategy-egypts-cervical-cancer/) - Before 2021, there was little official focus on cervical cancer in Egypt. The World Health Organization's 2021 report indicated that fewer than 1 in 10 Egyptian women had been screened for cervical cancer in the previous five years. That was the year that gynaecologic oncology consultant Mohamed Elazab founded the Egyptian Society For Colposcopy And
- [Inequalities in cancer mortality highlight need to adapt approaches to local conditions](https://cancerworld.net/inequalities-in-cancer-mortality-local-conditions/) - The risk of dying from cancer is highest for men and women living in areas with greater poverty. A study into small-area variations in cancer mortality statistics between different English health districts, published in Lancet Oncology, 11 December, found that the risk of dying from cancer was more than 70% higher in the poorest areas
- [Exercise boosts quality of life in metastatic breast cancer](https://cancerworld.net/exercise-boosts-quality-of-life-in-metastatic-breast-cancer/) - People with metastatic breast cancer taking part in a nine-month structured exercise programme report less fatigue and improved quality of life in comparison to controls. The study, abstract GS02-10, presented at the San Antonio Breast Cancer Symposium, held December 5–9, 2023, also showed the exercise group experienced less pain and shortness of breath than the
- [Tackling the crisis in Europe’s oncology workforce](https://cancerworld.net/tackling-the-crisis-in-europes-oncology-workforce/) - "We’ve heard politicians saying, ‘It's a time bomb’. No, it's not a time bomb. We see the system is cracking completely right now." Norbert Couespel, senior coordinator of policy research at the European Cancer Organisation, voices his deep frustration at the failure of Europe’s leaders to address the crisis in their healthcare workforces. Having spent
- [Regional cancer centres to boost access to cancer care across Uganda](https://cancerworld.net/regional-cancer-centres-to-boost-access-to-cancer-care-across-uganda/) - The Uganda Cancer Institute, set up in Kampala in 1967 as a centre for research and treatment of lymphoma, was one of the first cancer treatment centres in East Africa, and continues to play a leading role as a national and regional centre of excellence. But it is entirely insufficient for the needs of a
- [Regular mammography offers best insurance against dying from breast cancer](https://cancerworld.net/regular-mammography-offers-best-insurance-against-breast-cancer-mortality/) - Women who regularly attend breast screening mammography have a reduced risk of breast cancer mortality. The Swedish study, Abstract R1-SSBR10, presented at the annual meeting of the Radiological Society of North America (RSNA), held in Chicago, Illinois, 26–30 November, found that women with breast cancer who attended all previous mammogram invitations were three times less
- [A European roadmap to improve men’s cancer outcomes](https://cancerworld.net/a-european-roadmap-to-improve-mens-cancer-outcomes/) - Ensuring gender-neutral HPV vaccination, more flexible GP access hours, and national cancer plans tackling gender specific needs are among the policies that have been identified to improve male cancer outcomes. The roadmap ‘Time to Accelerate: Action on Men and Cancer’, launched at the European Parliament, 29 November, calls for European policy makers to give higher
- [Potential new target to prevent pancreatic cancer from spreading to liver](https://cancerworld.net/potential-new-target-to-prevent-pancreatic-cancer-from-spreading-to-liver/) - A mechanism that facilitates pancreatic cancer cells spreading to the liver has been elucidated. The study, published in Cell Reports, 2 November, identifies a ‘therapeutic vulnerability’ where the protein Netrin-1, which is upregulated when pancreatic cancer cells metastasise to the liver, can be suppressed with a monoclonal antibody. “By studying pancreatic cancer that had spread
- [Geriatric oncology: how physicians in Latin America are personalising treatments and changing attitudes](https://cancerworld.net/geriatric-oncology-personalising-treatments/) - When Gerardo Silveyra, a retired chemist from Toluca, Mexico, thinks about his recently deceased mother, Guadalupe Contreras, he regrets not having taken her to see a geriatrician sooner. Contreras, who died aged 93, had been “a very active woman,” and when she started having seemingly isolated health issues early in 2020, her family went through
- [Study indicates people with type 2 diabetes need increased colorectal cancer screening](https://cancerworld.net/study-type-2-diabetes-colorectal-cancer-screening/) - People with type 2 diabetes have a 47% increased risk of developing colorectal cancer (CRC) in comparison to people without diabetes. The cohort study, published in Jama Network Open, 15 November, suggests that regular CRC screening should become integral to healthcare provision for patients with type 2 diabetes. “Increased interactions with the healthcare system following
- [Further and faster: ECO mobilises to accelerate momentum from Europe’s Beating Cancer Plan](https://cancerworld.net/further-and-faster-eco-to-accelerate/) - “All over Europe new initiatives are being triggered. New communities of action are being formed, from young cancer trainees taking part in interspecialty training together, to cancer centres in every country getting ready to be part of a brand new network of cooperation. New screening plans and initiatives are taking place. And every country is
- [Ultra-sensitive immunoassay detects key protein produced by cancer cells](https://cancerworld.net/ultra-sensitive-immunoassay-detects-key-protein-produced-by-cancer-cells/) - A blood test detecting a key protein produced by cancer cells is showing promise as an early indicator of cancer. The study, published in Cancer Discovery, September 12, suggests that the ultra-sensitive assay for LINE-1-ORF1p offers potential as an effective ‘binary’ methodology for the early detection of multiple cancers and for monitoring response to treatment.
- [Angiogenesis: how cutting the blood supply became a tool against cancer](https://cancerworld.net/angiogenesis-how-cutting-the-blood-supply-became-a-tool-against-cancer/) - The human body is permeated by an extensive network of approximately sixty thousand miles of blood vessels – an intricately organised system designed for the precise and efficient distribution of oxygen and nutrients to all cells and organs, and for the removal of waste products, such as carbon dioxide. Nearly all metabolically active tissues are
- [The cardiovascular system – what we’ve learned since our ‘cave man’ days](https://cancerworld.net/the-cardiovascular-system-what-weve-learned-since-our-cave-man-days/) - The history of our understanding of the cardiovascular system is long and fascinating. As we gather from cave paintings, the Palaeolithic bowmen already knew that they should aim at the heart of the prey for an efficient kill. The earliest known description of the circulatory system can be traced back to Ancient Egyptian medical papyri,
- [Induction chemotherapy delivers first survival benefit in locally advanced cervical cancer for two decades](https://cancerworld.net/induction-chemotherapy-survival-benefit/) - A short course of induction chemotherapy prior to chemoradiation improved survival in locally advanced cervical cancer. The study, presented in a Presidential Symposium at the ESMO 2023 Congress, abstract LBA8, found that induction chemotherapy (paclitaxel and carboplatin) prior to chemoradiation taken for just six weeks reduced the risk of death by 39% and disease progression
- [HPV vaccination: generating demand by spreading knowledge and information](https://cancerworld.net/hpv-vaccination-generating-demand-by-spreading-knowledge-and-information/) - "The most sustainable way is for people to understand that when my girl reaches 10 years, I just take her for the HPV vaccine. That's the sustainable way where all of us take responsibility. We either hold our daughters' hands or send them with a clear message: 'Today is your 10th birthday, and on your
- [Aleksandra Filipovic: where scientific innovation meets holistic care](https://cancerworld.net/aleksandra-filipovic/) - An oncologist committed to delivering a very personal, holistic care, Aleksandra Filipovic has grown into her current role at PureTech Health – a clinical stage biopharma company – where she is Head of Oncology, working with academic and industry scientists to accelerate the development of innovative therapies. She still sees patients at a weekly clinic
- [Ultra-high dose rate radiation: is FLASH the future? ](https://cancerworld.net/ultra-high-dose-rate-radiation-is-flash-the-future/) - Radiation that kills only tumour cells and spares healthy tissue? It sounds too good to be true. But if the promise of recent research is fulfilled, the FLASH technique of ultra high dose-rate delivery could present the greatest transformation of radiotherapy – a treatment required by half of all cancer patients – since the introduction
- [A more excellent way: Integration of science, medicine and holistic practices in Oncology and Life](https://cancerworld.net/a-more-excellent-way/) - The emotion is palpable as these words come through. I remember eagerly awaiting the new issue of Cancerworld when I was a medical student, at Serbia's Niš University, to read the fascinating journeys of those I so looked up to. I still, for example, remember the interviews with Martine Piccart and Jacek Jassem and their
- [Gut microbiome offers new avenue for detecting colorectal cancer](https://cancerworld.net/gut-microbiome-detecting-colorectal-cancer/) - Significant variations in the gut microbiome can be identified between people who develop pre-cancerous colonic lesions and those who do not. The Dutch study, abstract OP118, presented at United European Gastroenterology (UEG) Week 2023, held in Copenhagen, October 14–17, showed that the diversity of the gut microbiome was decreased in patients who went on to
- [Machine learning improves accuracy of survival prediction](https://cancerworld.net/machine-learning-survival-prediction/) - An artificial intelligence prototype has been developed to estimate the survival of newly diagnosed cancer patients with breast, thyroid, and pancreatic cancers. The study, abstract 4160, presented at the American College of Surgeons (ACS) Clinical Congress 2023, October 22–25, Boston, found that age at diagnosis, tumour size, whether the patient had surgery, and time from
- [Voices from WOF: “We have to shift from the thinking: we’ll tell everybody what to do and they will all get better”](https://cancerworld.net/voices-from-wof-ben-anderson/) - What progress can we point to? I think there has been a lot of progress and it has been incremental. Ten years ago, one of the biggest obstacles was the belief that this is not going to work. When we started 20 years ago doing the Breast Health Global Initiative for low- and middle-income countries,
- [Voices from WOF: “We need another approach to funding, where governments together with development banks play the overarching role”](https://cancerworld.net/voices-from-wof-franco-cavalli/) - What progress can we point to? Firstly, there is more awareness in the community about cancer, and that cancer is becoming increasingly a problem of developing countries. Fifteen years ago everyone was thinking that cancer was a disease of the rich countries. Now we know this is less and less the case. Significant progress has
- [Voices from WOF: “We need to ensure we have accountability, and simplify the metrics on what success looks like”](https://cancerworld.net/voices-from-wof-bente-mikkelsen/) - What progress can we point to? I think it has been a fabulous 10 years. We’ve really seen that the awareness and global political commitment is much stronger than 10 years ago. We have much better data, we publish the data, people have no excuse for not using the data. Partnerships, the organisations, are really
- [Voices from WOF: “We need to make care affordable and strengthen our health workforce”](https://cancerworld.net/voices-from-wof-srinath-reddy/) - What progress can we point to? I think there has been a tremendous amount of progress in understanding the dimensions and distribution of cancer as a growing global threat. Not only about the types of cancer in each region, but also the magnitude of the problem – how it is affecting larger numbers in terms
- [Voices from WOF: “In this post-Covid world we have new opportunities to harness technology”](https://cancerworld.net/voices-from-wof-felicia-marie-knaul/) - What progress can we point to? In today’s global health world, we do now understand that noncommunicable diseases [NCDs] are a priority, and within NCDs, that cancer is the highest priority. But are countries discussing this, and thinking about strategies? I think we have some important and specific country examples, and some very interesting platforms
- [Voices from WOF: “We need to think critically about how our healthcare system can deliver the best for patients”](https://cancerworld.net/voices-from-wof-miriam-mutebe/) - What progress can we point to? In Africa, there is a growing awareness of cancers, not just among the healthcare professionals but also communities. This has been largely due to grassroots advocacy – people who were cancer champions coming out and saying: “Listen I had cancer, it was picked up early, I am surviving and
- [Voices from WOF: “We’ve been talking to decision makers for 20 years. It hasn’t worked. We have to engage better with the public”](https://cancerworld.net/voices-from-wof-gospodarowicz/) - What progress can we point to? In the last 10 years we have seen significant progress in science and the depth of understanding of cancer – its complexity and biology. We also have new tools available, so patients with cancer can be treated better, can expect better outcomes and have generally better survival. Though we
- [Voices from WOF: What is not being discussed is how do we improve wellbeing?](https://cancerworld.net/voices-from-wof-bhoo-pathy/) - What progress can we point to? I think we have made good progress in prevention, secondary prevention, especially in terms of screening for cervical cancer, HPV vaccination, elimination of cervical cancer – that is where we are heading in the right way. There’s a lot of global action that has been trickling down very well,
- [Walkable neighbourhoods lower risk of obesity related cancers](https://cancerworld.net/walkable-neighbourhoods-lower-risk-of-obesity-related-cancers/) - Women living in US neighbourhoods with higher levels of ‘walkability’ have lower risks of obesity related cancers, including postmenopausal breast, endometrial, ovarian, and multiple myeloma. The prospective study, published in Environmental Health Perspectives, 10 October, found women living in neighbourhoods judged to be in the top quartile of neighbourhood ‘walkability’ had a 26% lower risk
- [Untreated malnutrition is rife among cancer patients: here’s how we can do better](https://cancerworld.net/untreated-malnutrition-cancer-patients-do-better/) - In the mid-1970s, the US medical community was shocked by an article published in Nutrition Today under the title ‘The Skeleton in the Hospital Closet’. "I suspect that one of the largest pockets of unrecognized malnutrition in America exists, not in rural slums or urban ghettos, but in the private rooms and wards of our
- [Advocating for accessible cancer care in the global South: are we doing this all wrong?](https://cancerworld.net/advocating-for-accessible-cancer-care/) - “You have to convince the people with their hands on the levers of power. They don’t see things as we see them. They have other problems on their minds…” Ten years after launching the Stop Cancer Now! appeal, which outlined the actions required to prepare low and middle-income countries for an escalation in the numbers
- [Dichloroacetate shows promise in treating cancer-related fatigue](https://cancerworld.net/dichloroacetate-cancer-related-fatigue/) - Dichloroacetate, a drug targeting the metabolism, helped alleviate cancer related fatigue in mouse models of melanoma and colon cancer, reports a study published in the American Journal of Physiology Endocrinology and Metabolism, 2 October. “This study tackles the long-understudied conundrum of CRF [cancer-related fatigue] treatment from multiple dimensions of muscle performance and metabolism. Our data reveal
- [Supporting mental health helps patients feel better – could it also improve cancer outcomes?](https://cancerworld.net/supporting-mental-health-improve-cancer-outcomes/) - Psychological stress is a known factor in numerous diseases from heart failure to auto-immune conditions. Evidence is now growing that implicates stress as a factor in cancer as well, with higher rates of recurrence and progression found in people experiencing higher levels of chronic stress. Researchers are starting to untangle the mechanisms at play, which
- [Combination immunotherapy with novel immune-oncology agents benefit NSCLC patients in presurgical setting](https://cancerworld.net/combination-immunotherapy-benefit-nsclc-patients/) - Patients with resectable non-small-cell lung cancer show improved major pathological response rates with combination immune oncology agents versus single-agent immunotherapy. The NeoCOAST trial, published in Cancer Discovery, 14 September, demonstrated that combining the anti-PD-L1 monoclonal antibody durvalumab with other novel immune oncology (IO) agents outperforms durvalumab alone in presurgical (neoadjuvant) settings for patients with resectable
- [Trial defines breast cancer population who can omit sentinel node biopsy](https://cancerworld.net/trial-defines-breast-cancer-omit-sentinel-node-biopsy/) - Breast cancer patients with no axillary lymph node involvement apparent on ultrasound scans, and with tumours less than 2cm, had similar outcomes regardless of whether they underwent sentinel lymph node biopsy or no axillary surgery. The results of the Italian SOUND study, published in JAMA Oncology, 21 September, suggest that many patients with these features
- [Statin use lowers risk of colorectal cancer in inflammatory bowel disease](https://cancerworld.net/statin-lowers-risk-colorectal-cancer/) - Statin use was associated with a lower risk of colorectal cancer, colorectal cancer related mortality, and all-cause mortality in a patient population with inflammatory bowel disease. The Swedish study, published online in eClinicalMedicine, 1 September, found benefits depended on duration of statin use, with a significantly lower risk after more than two years use. “Our
- [New drug breaks through fibrotic tissue in pancreatic cancer](https://cancerworld.net/new-drug-breaks-through-fibrotic-tissue-in-pancreatic-cancer/) - A drug targeting scar-like ‘fibrotic’ tissue within tumours shows promise for treating pancreatic ductal adenocarcinoma (PDAC). In the study, reported online in Nature Cancer, 28 August, Australian investigators showed in mouse and human models of PDAC that, when the drug PXS-5505 was given in combination with chemotherapy, survival time was significantly increased and metastasis significantly
- [Anticancer benefits from Mediterranean 'lifestyle' can be transferred to non-Mediterranean population](https://cancerworld.net/anticancer-benefits-mediterranean-lifestyle/) - High adherence to a ‘Mediterranean lifestyle’ is associated with lower cancer mortality in a dose-responsive manner. The study, published in Mayo Clinic Proceedings (16 August), showed that UK adults who are the most adherent to a Mediterranean lifestyle have a 29% lower risk of all-cause mortality and 28% lower risk of cancer mortality compared to
- [Hospice caring for women with cervical cancer launches own mobile screening clinic](https://cancerworld.net/hospice-caring-for-women-cervical-cancer/) - It’s 9.30 in the heart of Kaliro district in eastern Uganda, and a group of women is already gathered outside the Nansololo Health Centre II by the time the van from the Rays of Hope Hospice Jinja arrives. They are not here to seek the expert palliative care that the hospice has been delivering to
- [Breast surgery: closing the quality gap in Poland](https://cancerworld.net/breast-surgery-quality-gap-poland/) - This investigation was prompted by the story of Julia, a lawyer who fled her home in Kyiv in the spring of 2022, as Russian forces were advancing on Ukraine’s capital. At the time, the mother of two was reaching the end of a course of neoadjuvant treatment for breast cancer, which she had been prescribed
- [Anti-oestrogen provides novel strategy to boost checkpoint inhibitors](https://cancerworld.net/anti-oestrogen-provides-novel-strategy/) - Adding anti-oestrogen therapy improves response to combined chemotherapy and immune checkpoint inhibition in tumours that do not express oestrogen receptors. The Japanese study, published in British Journal of Cancer, provides a new rationale for introducing therapies blocking oestrogen signalling to boost the anti-tumour effects of immune therapy. “We have demonstrated that anti-oestrogenic therapies can potentially
- [UK’s cancer research has lost its independent voice: what will it mean for patients?](https://cancerworld.net/uks-cancer-research-has-lost-its-independent-voice/) - How do you get the greatest impact for patients from the sum total of a nation’s clinical cancer research efforts? The answer that the UK came up with at the start of the new millennium was the National Cancer Research Institute – a body designed to bring collaboration and partnership into cancer research, to reduce
- [Our new journal from India is enriching the cancer publications landscape](https://cancerworld.net/our-new-journal-from-india-cancer/) - We launched Cancer Research, Statistics and Treatment at the internationally renowned Tata Memorial Hospital, Mumbai, in 2018. It was my colleague, Professor of Medical Oncology, Kumar Prabhash, who prodded me to start the journal. I had already been the Editor-in-Chief of South Asian Journal of Cancer, but had stopped to focus on my clinical commitments
- [Shared decision making: translating our aspirations into clinical practice](https://cancerworld.net/shared-decision-making/) - Despite growing awareness of the importance of shared decision making in cancer, there is plenty of evidence that it is still not being implemented as it should be. A national survey of patient experience from the Danish Cancer Society found that three in four Danish cancer patients would prefer treatment decisions to be made jointly
- [Europe’s patient advocates skill up to better influence cancer care and research agendas](https://cancerworld.net/europes-patient-advocates-reasearch-agenda/) - Patient advocates for a wide range of cancer communities across Europe spent four days at the start of July honing the skills they need to influence the policy, research and healthcare decisions that matter to them. This was the second face-to-face ‘Academy’ run by WECAN, the Workgroup of European Cancer Patient Advocacy Networks, a platform
- [Transcriptional signature provides clue to CAR T cell longevity](https://cancerworld.net/transcriptional-signature-provides-clue-to-car-t-cell-longevity/) - A transcriptional signature of 21 genes has been found to occur across patients with paediatric B-cell acute lymphoblastic leukaemia who have durable responses and long-lived CAR T cells. The UK study, published online in Nature Medicine, July 6, did not identify the signature in non-CAR T cells from the same patients, but did find it
- [Cardiorespiratory fitness reduces risk of developing and dying from cancer](https://cancerworld.net/cardiorespiratory-fitness-reduces-risk-of-developing-and-dying-from-cancer/) - Higher levels of cardiorespiratory fitness may reduce the incidence and mortality of specific cancers in men. The Swedish male cohort study, published online in JAMA Open Network, June 29, found that higher levels of cardiorespiratory fitness were associated with a lower risk of developing colon and lung cancer and a lower risk of death from
- [Four-protein biomarker test helps personalise lung cancer screening](https://cancerworld.net/four-protein-biomarker-test-helps-personalise-lung-cancer-screening/) - Integrating a panel of four circulating protein biomarkers with a lung cancer risk model identified individuals at high risk of developing fatal lung cancer. The study published in Journal of Clinical Oncology, June 28, demonstrated how including the biomarkers in selection of candidates for screening could help distinguish people likely to develop a lethal lung
- ['The future of cancer treatment', as seen by Tak Mak, whose lab paved the way for T- cell receptor based immunotherapies](https://cancerworld.net/the-future-of-cancer-treatment-tak-mak-t-cell-receptor-immunotherapies/) - Ni Miikana is a Native American expression meaning "my path". My path, my journey in science is not about me, it is about the institutions that have supported us and the many mentors and mentees who made this talk possible. 250 years ago, a French philosopher, Voltaire, said: “Doctors pour drugs they know little about,
- [Immune resilience: a clue to why some people live longer, have fewer infections, and get less recurrent cancer](https://cancerworld.net/immune-resilience-a-clue-to-why-some-people-live-longer-have-fewer-infections-and-get-less-recurrent-cancer/) - Kidney transplant patients with high immune resilience, defined as the capacity to preserve/restore immunocompetence and control inflammation during inflammatory stress, are less likely to develop recurrent skin cancer compared to those with low immune resilience. An international study, published online in Nature Communications, 13 June, found that immune resilience differs widely among individuals. In addition
- [Cancer drugs for Africa… from Africa?](https://cancerworld.net/cancer-drugs-for-africa-from-africa/) - More than two years ago, Cipla Quality Chemical Industries, a pharmaceutical manufacturing company in Kampala, Uganda, announced that it would start producing cancer drugs. In a deal agreed in 2021 with the Ministry of Health, the company, which is part of a large multinational – agreed to add oncology drugs to its current list of
- [The CRISPR revolution: it’s transforming cancer research, can it do the same for treatment?](https://cancerworld.net/the-crispr-revolution-transforming-cancer-research-treatment/) - CRISPR is a revolutionary gene-editing tool that allows scientists to cut DNA with extraordinary precision and make changes to the genome. The technology was a gift to cancer researchers, whose efforts to understand the roles played by different genes rely on seeing what happens when a gene is knocked out or modified. For centuries this
- [Bacterial decolonisation offers new strategy to prevent acute radiation dermatitis](https://cancerworld.net/bacterial-decolonisation-prevent-dermatitis/) - Many cases of acute radiation dermatitis involve the common skin bacterium Staphylococcus aureus. Two linked papers in the same issue of JAMA Oncology, published online 4 May, suggest bacterial decolonisation of Staphylococcus aureus (S aureus) offers an effective approach for preventing this burdensome skin reaction. The first paper demonstrated S aureus colonisation to be an
- [New options to protect long-term health of children treated for cancer](https://cancerworld.net/new-options-protect-health-children-cancer/) - Childhood cancer is considered a success story of modern medicine, with more than 90% of children now surviving long-term in high-income countries, up from just 10% 65 years ago. Yet many children who survive their cancer go on to experience a myriad of long-term treatment side effects, which can affect every major system and organ
- [Slow decrease in breast density heightens breast cancer risk](https://cancerworld.net/slow-decrease-breast-density-cancer-risk/) - Women with a slower decrease in breast density over time are at higher risk of developing breast cancer. The prospective cohort study, published in JAMA Oncology, online April 27, suggests that dynamic changes in breast density over time can be used to refine risk stratification and guide more individualised screening. “By adding the change in
- [AI-generated radiotherapy planning could boost access to high-quality treatment across the globe](https://cancerworld.net/ai-generated-radiotherapy-access-treatment-globe/) - An international study to trial if AI-generated radiation therapy planning can deliver in resource-poor countries for head and neck, cervical and prostate cancer.
- [Prehabilitation programmes benefit breast cancer patients and save healthcare resources](https://cancerworld.net/prehabilitation-programmes-benefit-breast-cancer/) - Referring patients with early-stage breast cancer to exercise programmes prior to surgery not only improves health-related quality of life measures but also lowers overall healthcare costs. The study, abstract 1385675, was presented at the American Society of Breast Surgeons Annual meeting, held in Boston April 27–30, 2023. A second study, abstract 1387186, also in patients
- [Obesity and cancer: 12 things clinicians and patients should know](https://cancerworld.net/obesity-and-cancer-12-things-clinicians-and-patients-should-know/) - The significant link that has been clearly established between obesity and risk of 13 types of cancer means that many patients in the ‘obese’ category can be offered an opportunity to improve their health and their prognosis. Currently, more often than not, that opportunity is being missed. Many clinicians are rightly wary of saying anything
- [Using ultrasound to open blood–brain barrier could be glioblastoma game changer](https://cancerworld.net/using-ultrasound-glioblastoma/) - A novel ultrasound device temporarily opens the blood–brain barrier to allow delivery of chemotherapy. The dose-escalation phase 1 study, published in Lancet Oncology, May 2, provides evidence that use of the new French technology leads to a fourfold increase in the concentration of paclitaxel and sixfold increase in concentration of carboplatin in the brains of
- [Precision cancer nursing: using the personalised medicine paradigm to improve patient care](https://cancerworld.net/precision-cancer-nursing-personalised-medicine/) - Tells from cancer nurse specialists who are driving innovation in precision cancer nursing: understanding of treatments, tools and evidence-based interventions.
- [CAR T cells v chemo for childhood leukaemia: are we ready for the next step?](https://cancerworld.net/car-t-cells-chemo-childhood-leukaemia/) - Child leukaemia: standard treatments that cure nine in ten patients but with toxic effects or CAR T cell treatment, more gentle never been tested in first line?
- [Brazil’s new head of cancer control sets out his strategy](https://cancerworld.net/brazils-head-cancer-control-strategy/) - Roberto de Almeida Gil is known for his easy smile. But the new director-general of Brazil’s National Cancer Institute (INCA) also has firm convictions and more than four decades of experience in oncology. He is clear that INCA – the Brazilian Ministry of Health's section for cancer prevention and control policies – has an important
- [Genetic targets identified for cancer-associated cachexia](https://cancerworld.net/genetic-cancer-associated-cachexia/) - Distinct patterns of genes have been shown to be active in the tumours of non-small-cell lung cancer patients who go on to develop cachexia, including high activity of the protein GDF15. The study, published in Nature Medicine, April 2023 issue, also demonstrated that participants with low subcutaneous adipose tissue, visceral adipose tissue, or skeletal muscle
- [Antimicrobial exposure linked to poorer survival in triple negative breast cancer](https://cancerworld.net/antimicrobial-triple-negative-breast-cancer/) - Each additional total or unique monthly antimicrobial prescription is associated with inferior overall and breast-cancer-specific survival in women with triple negative breast cancer (TNBC). The study published in Nature Communications, 12 April 2023, found that the association was directly related to lymphocyte count. “We found a surprisingly strong and sustained increased risk of death in
- [Ian Magrath: a visionary who prepared the ground for the global oncology initiatives of today](https://cancerworld.net/ian-magrath-a-ground-for-global-oncology-initiatives/) - Ian Magrath, lymphoma specialist and champion of cancer care in the developing world, has died in Brussels, aged 78. An exceptional cancer researcher, physician and teacher, he will be remembered for his pioneering role putting cancer care on the global health agenda. Magrath was among the earliest voices to challenge perceptions that cancer is a
- [How do I respond? Advice for friends and family on supporting someone through cancer](https://cancerworld.net/how-do-i-respond-friends-family-cancer/) - A few days after being diagnosed with cancer, at only 32 years of age, Katarzyna Chmielewska-Wojciechowska met a friend who asked, in passing, how she was doing. She told him. His response was to sympathise and offer reassurance. He knew how she felt, because his father had been through it. “But dad had the worst
- [Trial platform informs precision treatment of childhood cancers](https://cancerworld.net/trial-platform-informs-precision-treatment-of-childhood-cancers/) - A stratified medicine basket study has shown the benefit of combining two targeted therapies to treat paediatric cancers with specific molecular profiles. The study, presentation number CT019, presented at the AACR (American Association for Cancer Research) Annual Meeting 2023, held 14–19 April, showed that combining the PARP inhibitor olaparib with the investigational ATR inhibitor ceralasertib
- [Personalised RNA vaccine combined with immune checkpoint inhibitor shows efficacy in melanoma](https://cancerworld.net/personalised-rna-vaccine-immune-checkpoint-inhibitor-melanoma/) - In advanced melanoma, adding a personalised mRNA-based vaccine to the immune checkpoint inhibitor pembrolizumab improved recurrence-free survival compared with pembrolizumab alone. The KEYNOTE-942 study (presentation number CT001), presented at the AACR (American Association for Cancer Research) Annual Meeting 2023, held April 14-19, found that adding the personalised vaccine mRNA-4157/V940 resulted in a 44% reduction in
- [Molecular tumour boards: translating data into tailored therapeutics](https://cancerworld.net/molecular-tumour-boards-tailored-therapeutics/) - Developments in molecular diagnostics are allowing us to capture an extraordinarily detailed picture of the genomic and other molecular changes that characterise a given tumour specimen. But making best use of the information at our disposal is proving quite a challenge. How do we deal with the ever-increasing amount of genomic data generated by new
- [Intermittent dosing of exemestane is non-inferior to daily dosing](https://cancerworld.net/intermittent-exemestane-dosing/) - Giving the aromatase inhibitor (AI) exemestane 25 mg three times weekly was non-inferior to the standard dosing of 25mg daily among study participants who complied with the schedule. The international, multicentric study, which was supported by the US National Cancer Institute, and published by Davide Serrano et al. in JAMA Oncology, March 23, found that
- [Unpaid women carers: recognising their contribution and their needs in Latin America](https://cancerworld.net/unpaid-women-carers-latin-america/) - Rising rates of cancer associated with aging in Latin America is leading to a rise in people – mostly women – leaving paid work to care for relatives.
- [Body weight influences breast cancer risk in women with BRCA1 and 2 mutations](https://cancerworld.net/body-weight-breast-cancer-risk-brca1-2-mutations/) - Obesity may be a factor contributing to DNA damage in the breast tissue of women with BRCA1 or BRCA2 mutations. The study, published in Science Translational Medicine, February 22, suggests maintaining a healthy body weight or pharmacologically targeting oestrogen or metabolic dysfunction, could offer new strategies for reducing risks of developing breast cancer in women
- [‘Fragile’ cancer patients hit by Turkish earthquake need urgent support](https://cancerworld.net/fragile-cancer-patients-earthquake-support/) - Many cancer patients from the regions affected by February’s earthquakes are still struggling to stay warm and safe and keep going with their treatments.
- [Improving outcomes in elderly patients taking multiple medications](https://cancerworld.net/improving-outcomes-elderly-multiple-medications/) - For older patients with cancer, taking multiple medications can result in toxic chemotherapy side effects and even the need to stop cancer treatment. The cohort study, published in Cancer, 24th January, found cancer patients with one or more potential drug interactions had a 59% higher odds of having to stop cancer treatment earlier then recommended.
- [Localised prostate cancer: active monitoring offers valid option](https://cancerworld.net/localised-prostate-cancer-active-monitoring/) - Active monitoring of localised prostate cancer has the same high rates of survival after 15 years as radiotherapy or surgery. The ProtecT trial, presented at the European Association of Urology (EAU) meeting in Milan, March 10–13, and published simultaneously in the New England Journal of Medicine, 11 March, showed that although men on active monitoring
- [Expert cancer surgery: could VR help speed up and standardise training?](https://cancerworld.net/expert-cancer-surgery-vr-training/) - Digital training for cancer surgery, learn skills by practising on virtual patients, receiving AI-generated feedback and advice on weak points: it that possible today?
- [A blood test for early detection of any cancer: What’s the ideal? Are we getting there?](https://cancerworld.net/blood-test-early-detection-any-cancer/) - Reports on the growing array of technologies and tests in development and trials of liquid biopsies as screening setting.
- [Plant-based diets cut risk of prostate cancer progression and recurrence by over 50%](https://cancerworld.net/plant-based-diets-cut-risk-prostate-cancer-progression-recurrence/) - Prostate cancer patients who consume the highest intakes of plant-based foods lower their risk of progression and recurrence. The study, abstract 392 presented at the 2023 American Society of Clinical Oncology (ASCO) Genitourinary Cancer Symposium, held in San Francisco, February 16–18, found that men with prostate cancer who reported the highest intakes of plant-based foods
- [Immunotherapy: three studies point to potential strategies to improve response](https://cancerworld.net/immunotherapy-strategies-improve-response/) - New data on the impact of diet, immune environment and prior use of antibiotics on response to immunotherapies in many cancer types.
- [Radiotherapy can be safely omitted in older women with low-risk breast cancer](https://cancerworld.net/radiotherapy-omitted-older-women-breast-cancer/) - Leaving out radiotherapy does not affect survival after breast-conserving surgery in older women with low-risk hormone-receptor-positive early breast cancer. Ten-year outcomes for the PRIME II trial, published in the New England Journal of Medicine, February 16, found that, although omission of radiotherapy was associated with a ten-fold increased incidence of local recurrence, there were no
- [Telomere shortening mediates tumour suppression](https://cancerworld.net/telomere-shortening-tumour-suppression/) - Shortening of telomeres, as occurs naturally with ageing, works through a pathway that involves mitochondria-activated immune responses to ultimately eliminate precancerous cells. The US study, published in Nature (8 February 2022), suggests that telomere shortening has evolved as a tumour-suppressive mechanism, and when this complex pathway becomes dysfunctional, cells evade destruction and become cancerous. “These
- [Food insecurity: Why screening for access to nutrition should be part of cancer treatment everywhere](https://cancerworld.net/food-insecurity-screening-access-nutrition-cancer-treatment-everywhere/) - Malnutrition and cancer: good nutrition is needed for people undergoing cancer treatment to sustain through toxic treatments and promote postoperative recovery.
- [Cancer care in Ukraine, one year on](https://cancerworld.net/cancer-care-in-ukraine-one-year-on/) - I make two appointments to speak to Anna Uzlova of Inspiration Family, a Kyiv-based foundation set up in September 2020 to support adult cancer patients. The first time the interview cannot take place because Uzlova is going to visit family out of the city. She texts me that “according to the schedule there will be
- [Childhood cancer: let’s close this equity gap of haves and have nots](https://cancerworld.net/childhood-cancer-close-equity-gap-haves-and-have-nots/) - Daniel McKenzie, Director of the Kidzcan foundation in Zimbabwe, describes what lies behind the childhood cancers survival gap, and what can be done to close it.
- [Epidemiological study sheds light on complex link between ovarian cancer and ovulation](https://cancerworld.net/epidemiological-study-sheds-light-on-complex-link-between-ovarian-cancer-and-ovulation/) - Women who ovulate for longer over the course of their lifetimes may have a higher risk of developing ovarian cancer. The international epidemiological study, published in Journal of the National Cancer Institute, 23 January, found that each additional year of ovulation was associated with a 4% increase in the risk of epithelial ovarian cancer. However,
- [Cancer could overtake cardiovascular disease as leading cause of death in type 2 diabetes](https://cancerworld.net/cancer-could-leading-cause-of-death-in-type-2-diabetes/) - Mortality from cancer has increased among older people with type 2 diabetes. The UK cohort study, published in Diabetologica, 24 January, found people with type 2 diabetes were at particular risk of mortality from colorectal, pancreatic, liver and endometrial cancers. “Our findings underline the growing cancer burden in people with type 2 diabetes, particularly in
- [Hansjörg Senn of St Gallen: A practice-changing career](https://cancerworld.net/hansjorg-senn-of-st-gallen-a-practice-changing-career/) - The speed of progress in breast cancer – not just survival, but also quality of life and survivorship – has been the envy of the wider cancer community for many decades. The factors contributing to this relative success are many – the role played by Hansjörg Senn, who died on January 13th, should be acknowledged
- [Study highlights need to reanalyse genomics and genetics of metastatic tumours](https://cancerworld.net/study-reanalyse-genomics-genetics-metastatic-tumours/) - Around one third of breast cancer patients showed molecular subtype shifts (especially involving luminal cancers) between their primary and metastatic tumours. The study, published in Nature Cancer, on December 30th, also revealed the presence of fewer immune cells in triple-negative (TNBC)/ basal-like metastases compared to primary tumour microenvironments. Together, the findings suggest immune therapies may
- [The cancer patients still struggling to access drugs in the wake of anti-corruption reforms](https://cancerworld.net/cancer-patients-struggling-access-anti-corruption-reforms/) - Miriam Espinoza, a food vendor from Michoacán, Mexico, still remembers the day she received her cancer diagnosis in 2019. After months of waiting for a CT scan and several visits to gynaecologists, who told her that the lump in her breast was fibrosis, she was finally sent for an emergency oncological consultation. The doctor told
- [Current cervical cancer screening paradigm fails older women](https://cancerworld.net/current-cervical-cancer-screening-paradigm-fails-older-women/) - Nearly one in five new cervical cancers diagnosed between 2009 and 2018 were in women aged 65 years and over. The US study, published in Cancer Epidemiology, Biomarkers and Prevention, January 9, demonstrates that relative to younger women, those aged 65 years and older present with later stage disease and have lower five-year survival. Publication
- [Immunotherapy: outcomes of ultra low-dose trial offer hope for better global access](https://cancerworld.net/immunotherapy-outcomes-ultra-low-dose-trial-global-access/) - Doctors at the Tata Memorial Hospital in Mumbai have shown that an ultra-low dose of the immunotherapy drug nivolumab significantly improves survival in patients with recurrent or newly diagnosed head and neck cancers. The findings of the single-centre phase III randomised controlled trial are significant because the trial protocol used just 6% of the recommended
- [Cervical cancer elimination efforts boosted by simpler ways to identify and treat pre-cancerous lesions](https://cancerworld.net/cervical-cancer-elimination-pre-cancerous-lesions/) - Projects in low-income countries show how to achieve WHO targets for eliminating cervical cancer treating pre-cancerous lesions found via the screening programmes.
- [Henry Rodriguez: driving the next step in precision medicine and international Cancer Moonshot cooperation](https://cancerworld.net/henry-rodriguez-precision-medicine-cancer-moonshot-cooperation/) - Precision cancer medicine aims to improve diagnosis and treatment at the molecular level. Although genomics has influenced what precision medicine encompasses today, research is at a turning point. There is currently a common public (and often governmental) misconception that data obtained from genomics alone provides all the necessary information to understand the biology of human
- [Call-to-arms for Europe to provide essential paediatric anti-cancer medicines](https://cancerworld.net/call-europe-provide-paediatric-anti-cancer-medicines/) - A European Society for Paediatric Oncology (SIOPE) project has defined 66 anticancer medicines considered essential for treatment of children with cancer. The study, published in The Lancet Oncology, 23 December 2022, represents the first pan-European effort to systematically analyse the definition of essential anticancer medicines for children, tailored to the realities of European health-systems. “With
- [Exercise-stimulated myokine production can extend survival in advanced prostate cancer](https://cancerworld.net/exercise-myokine-production-survival-prostate-cancer/) - After a bout of high-intensity interval training, men with advanced prostate cancer showed acute elevations of anti-cancer myokines in their serum. The study, published in Prostate Cancer and Prostatic Diseases, (29 November 2022), then demonstrated growth suppression of prostate cancer cell lines exposed to serum obtained immediately post exercise. “The findings from our work are
- [Five San Antonio take-aways to improve care of breast cancer patients](https://cancerworld.net/five-san-antonio-take-aways-to-improve-care-of-breast-cancer-patients/) - The 2022 San Antonio Breast Cancer Symposium, hosted in association with the American Association for Cancer Research (AACR), was held December 6–10, 2022. More than 8,000 researchers, clinicians, students, and patient advocates from 90 countries attended the meeting, which focused on the latest advances in the biology, aetiology, prevention, diagnosis and therapy of breast cancer.
- [Repurposed drug combination reduces risk of recurrence following surgery for colorectal cancer](https://cancerworld.net/repurposed-drug-reduces-risk-recurrence-surgery-colorectal-cancer/) - Pharmacological suppression of adrenergic and inflammatory signalling using readily available drugs to lower blood pressure and reduce anxiety decreased the risk of post-surgical colorectal cancer (CRC) recurrence. The pilot COMPIT study, published in the European Journal of Surgical Oncology, 6 December, found that the simultaneous administration of propranolol and etodolac significantly reduced the risk of
- [What do you say when your patient can’t stop worrying about recurrence? Here’s what you told us](https://cancerworld.net/what-say-when-patient-worrying-recurrence/) - A Cancerworld survey revealed some valuable insights on how confident oncologists feel in responding to patients’ persistent fears of recurrence.
- [Aerobic activity to outcompete metastasis ](https://cancerworld.net/aerobic-activity-to-outcompete-metastasis/) - Aerobic exercise can reduce the risk of developing metastatic cancer by 73%. Using both human epidemiological data and in vivo mouse models of melanoma metastasis, Israeli investigators report in Cancer Research (November 15) that high-intensity aerobic exercise increases glucose consumption by internal organs, thereby reducing the energy available for tumours to spread. “Our results suggest
- [Black in Cancer holds inaugural conference in London](https://cancerworld.net/black-in-cancer-holds-inaugural-conference-in-london/) - Black researchers, clinicians and advocates are linking up to get seen and heard and promote shared agendas.
- [A Health Data Space for patients, science, policy and industry: can Europe make it work?](https://cancerworld.net/a-health-data-space-for-patients-science-policy-and-industry-can-europe-make-it-work/) - Why the European proposal that will impact on every individual, team or institution who controls or wants access to health data has not generated wider discussion.
- [Ending cancer inequalities: European summit showcases new tools to inform policy](https://cancerworld.net/ending-cancer-inequalities-european-summit-showcases-new-tools-to-inform-policy/) - Two ambitious data initiatives aimed at tracking a wide range of inequalities that contribute to big differences in the risk of dying from cancer were highlighted in the opening session of the 2022 European Cancer Summit, held in Brussels, November 15 and 16. The first of these was the European Cancer Inequalities Registry, which is
- [Nanotechnology is steadily expanding its many roles in tackling cancer](https://cancerworld.net/nanotechnology-is-steadily-expanding-its-many-roles-in-tackling-cancer/) - Once seen as the poster child for high-tech approaches to treating cancer, nanotechnologies are now finding leading roles in a broad range of cancer applications.
- [Biological differences revealed between dense and nondense breast tissue](https://cancerworld.net/biological-differences-revealed-between-dense-and-nondense-breast-tissue/) - Postmenopausal women with dense breast tissue compared to women of the same age who do not have dense tissue demonstrate upregulation of 124 proteins which may be responsible for creating pro-tumorigenic microenvironments. The study, published in the British Journal of Cancer, 31 October, found women with dense breast tissue had upregulation of 65 proteins linked
- [First voluntary licensing of cancer drug sets ‘vital precedent’ for the industry](https://cancerworld.net/first-voluntary-licensing-of-cancer-drug-sets-vital-precedent-for-the-industry/) - Access to essential cancer medicines: Novartis and the Medicines Patent Pool agreed on facilitate production in LMIC countries of generic versions of on-patent nilotinib.
- [Leave no-one behind](https://cancerworld.net/leave-no-one-behind/) - Cancerworld is moving online, which means this will be the last printed version. We’re all sad to see the end of a physical magazine, which gave our readers real pages to turn, and the chance to take time away from the screens that now dominate our lives. But having been online-first for a few years
- [Knowing ‘functional prognosis’ helps cancer patients plan unfinished business](https://cancerworld.net/knowing-functional-prognosis-helps-cancer-patients-plan-unfinished-business/) - More cancer patients want to be informed about their future functional prognosis than their life expectancy. The Japanese survey, published in Annals of Palliative Medicine, October 28, found that almost half of patients wanted to know about their functional progress compared with around one in four who wanted to know their life expectancy. It also
- [Michael Sporn: A pioneer in prevention and a unique and special friend](https://cancerworld.net/michael-sporn-a-pioneer-in-prevention-and-a-unique-and-special-friend/) - Michael B. Sporn, an internationally recognised cancer researcher who was one of the discoverers of the tumour growth factor TGF beta and a strong advocate of Cancer Prevention, died on September 29, 2022 at his home in Tunbridge, Vermont. He was 89. His prolific career was devoted to developing new approaches and drugs fo cancer,
- [Born to be walkers? How to stay healthy in a sedentary world](https://cancerworld.net/born-to-be-walkers-how-to-stay-healthy-in-a-sedentary-world/) - In a world where physical activity is no longer used for securing food, how do we incentivise to get the exercise we know is important for our health?
- [Tackling cancer when there’s no functioning state: the Al-Amal model](https://cancerworld.net/tackling-cancer-when-theres-no-functioning-state-the-al-amal-model/) - Six years ago, Mada accompanied her daughter to the gynaecologist for an early pregnancy scan. Whilst she was there, the physician suggested Mada herself get a check-up. “The doctor at first thought I had a very large cyst on my ovary,” Mada recalls. “They later found out it was not a cyst, but that the
- [New target identified for preventing cachexia](https://cancerworld.net/new-target-identified-for-preventing-cachexia/) - Targeting a specific enzyme in muscle could help cancer patients avoid the muscle wasting condition cachexia. The study, published in PNAS (October 17), found that a previously overlooked enzyme, known as UBR2, plays a critical role in cancer patients developing cachexia, by selectively degrading two myosin heavy chain subtypes. “We believe that we have identified
- [Radiotherapy benefits survival in patients with asymptomatic metastases](https://cancerworld.net/radiotherapy-benefits-survival-in-patients-with-asymptomatic-metastases/) - Treating high-risk, asymptomatic bone metastases with prophylactic radiation therapy reduces painful complications and extends overall survival. The study, abstract LBA 04, presented at the American Society for Radiation Oncology (ASTRO) Annual Meeting, held October 23–26, 2022, in San Diego, California, demonstrated that radiotherapy reduces skeletal-related events and hospitalisations for skeletal-related events. “This first randomized trial
- [Tobacco industry still exerting power in Eastern Europe](https://cancerworld.net/tobacco-industry-still-exerting-power-in-eastern-europe/) - Despite major progress in 2016, when the Romanian Parliament banned smoking in all indoor public spaces, indoor workplaces and public transportation, the country still has a tobacco problem. Around three in ten Romanians over the age of 15 are tobacco users and Romania is one of the few EU member states where the proportion of
- [Helping cancer patients preserve their fertility in one of Europe’s least supportive states](https://cancerworld.net/helping-cancer-patients-preserve-their-fertility-in-one-of-europes-least-supportive-states/) - Efforts to ensure patients can keep open the option of having children after cancer treatment are being hampered in Poland by the lack of any national, funded, fertility service
- [Project ECHO: spreading access to specialist care through democratising knowledge](https://cancerworld.net/project-echo-spreading-access-to-specialist-care-through-democratising-knowledge/) - One doctor’s pragmatic solution to widening access to specialist hepatology care in his locality is now being adapted to improve delivery of cancer services across the globe.
- [Fungal communities are a key part of cancer cell biology](https://cancerworld.net/fungal-communities-are-a-key-part-of-cancer-cell-biology/) - The first pan-cancer mycobiome atlas has revealed the presence of microfungi in 35 types of cancer, with the presence of some fungi correlating with overall survival. The findings of associations between cancer and the human mycobiome were published in Cell, 29 September. This discovery is so important that Nature dedicated an editorial to the topic.
- [Melanoma: treatment sequence matters](https://cancerworld.net/melanoma-treatment-sequence-matters/) - Patients with metastatic melanoma who received immunotherapy before targeted therapy showed a 20% overall survival advantage at two years versus those receiving targeted therapy first, with immunotherapy after. The final results of the DREAMseq trial, published in the Journal of Clinical Oncology (September 26), concluded that the combination of nivolumab/ ipilimumab followed by BRAF and
- [Cancer and the immune system: turning insights into treatments](https://cancerworld.net/cancer-and-the-immune-system-treatments/) - Two years of Cancerworld coverage of progress in developing immune-related treatment strategies and some insights into how it’s going
- [Cancer metastasis hijacks process healthy cells use to move around the body](https://cancerworld.net/cancer-metastasis-hijacks-process/) - Blocking the activity of an ion channel in a mouse model of cancer triggered metastasis independent of tumour formation. The study, published in Nature Genetics, 29th September, found that the process was not just restricted to mice with cancer; when NALCN was removed from mice without cancer it caused healthy cells to leave their original
- [Addressing the pathological hole at the core of many LMIC cancer plans](https://cancerworld.net/addressing-the-pathological-hole-lmic-cancer-plans/) - A patient visits their local primary care facility with symptoms that could indicate a possible cancer. What happens next could determine their chances of survival. In the event that it turns out to be a cancer, a quick and accurate diagnosis could be essential. Primary care doctors can look and feel and make a judgement
- [Advocates call for action to tackle damaging delays in myeloma diagnosis](https://cancerworld.net/advocates-to-tackle-delays-in-myeloma-diagnosis/) - Over one-third of European myeloma patients experience delays in diagnosis. ‘Myeloma Diagnosis Across Europe’, a pan-European survey and focus groups report published on European Myeloma Day (September 27th), revealed a landscape where diagnosis of myeloma can take over five months, require more than four medical consultations and involve visits to at least three different medical
- [Hope on horizon for blood test detecting unscreenable cancers](https://cancerworld.net/hope-blood-test-detecting-unscreenable-cancer/) - Multi-cancer early detection (MCED) tests offer a feasible approach for detecting 36 different types of cancer, over two thirds of which have no screening tests available. The PATHFINDER study, reported at the European Society for Medical Oncology (ESMO) Congress 2022, held 9-13 September, Paris, represents the first prospective investigation to show MCED tests can detect
- [NSCLC and climate change share common cause in particulate matter](https://cancerworld.net/nsclc-climate-change-common-cause-particulate-matter/) - Particles found in vehicle exhaust and combustion of fossil fuels are associated with non-small cell lung cancer (NSCLC) risk. A study presented in the Presidential Symposium at the European Society for Medical Oncology (ESMO) Congress 2022, held 9-13 September, showed increasing exposure to 2.5 µm particulate matter (PM2.5) increases NSCLC risk in non-smokers with EGFR mutations.
- [How organoids could help match treatments to tumours](https://cancerworld.net/how-organoids-could-help-match-treatments-to-tumours/) - Organoids are already being used to help select treatments for certain rare cancers: imagine being able to test early how different treatment options act against your patient’s tumour.
- [UK consensus group calls for biomarker testing at point of diagnosis](https://cancerworld.net/uk-group-calls-biomarker-testing-diagnosis/) - All cancer patients should be offered genomic profiling of their tumours at the point of diagnosis and during treatment to shape care and track how their disease evolves and responds to treatment. These were the conclusions of a UK consensus group, convened by the Institute of Cancer Research, London, published in July 2022, which said
- [Frequent aspirin use associated with ovarian cancer risk-reduction](https://cancerworld.net/frequent-aspirin-ovarian-cancer-risk-reduction/) - Frequent aspirin (acetyl salicyclic acid) use is associated with lower ovarian cancer risk regardless of the presence of most ovarian cancer risk factors. The meta-analysis of data from two ovarian cancer consortia, published in Journal of Clinical Oncology, 22 July, found risk reductions were also observed among women with multiple ovarian cancer risk factors. “This
- [Woman or man? Is precision medicine overlooking key biological differences?](https://cancerworld.net/is-precision-medicine-overlooking-key-biological-differences/) - As precision medicine seeks to define in minute detail the molecular biology of every tumour, might we be overlooking important biological differences between men and women?
- [Abnormal collagen provides ‘invisibility cloak’ in pancreatic cancer offering new therapeutic targets](https://cancerworld.net/abnormal-collagen-invisibility-cloak-pancreatic-cancer/) - Cancer cells produce an atypical collagen in pancreatic cancer creating an extracellular matrix that influences the tumour microbiome to protect against immune responses. The study, published in Cancer Cell, July 21, suggests that such abnormal collagen could provide a new therapeutic target for a range of cancers. “It turns out that the collagen made by
- [Peter Boyle: a high-impact epidemiologist with contagious dreams](https://cancerworld.net/peter-boyle-epidemiologist-with-dreams/) - Peter Boyle, an outstanding epidemiologist who used the power of statistics to help inform and influence policy at European and global levels, died on July 23 after a long illness, at the age of 71. In an era when Europe was looking to take a lead promoting public health, Boyle was a central figure providing
- [Resistant starch equivalent to eating a daily banana cuts hereditary cancer risk](https://cancerworld.net/resistant-starch-banana-cuts-hereditary-cancer-risk/) - Consuming resistant starch (RS), also known as fermentable fibre, reduces the risk of non-colorectal cancers (non-CRCs) by nearly 50% in people with Lynch syndrome. The study, published in Cancer Prevention Research, 25 July, found that while resistant starch significantly reduced upper GI cancers (e.g., gastric, biliary tract, pancreatic and duodenal cancers) in comparison to placebo,
- [Getting the message across: we need to learn from the Covid experience](https://cancerworld.net/getting-the-message-across-we-need-to-learn-from-the-covid-experience/) - One of the big lessons of the Covid pandemic has been the critical importance of good communication – how challenging it is to get complex medical information across to the general public, and the damage that poor communication can do. The lesson raises questions about whether we are offering medical students the breadth of training
- [Begging for imatinib: why do so many patients still lack access to this lifesaver?](https://cancerworld.net/begging-for-imatinib-why-do-so-many-patients-still-lack-access-to-this-lifesaver/) - Following doctor’s orders doesn’t usually mean making a two-hour round trip to visit your hospital twice a week to beg for any spare medication on the off-chance that someone has had to change to a different drug, or was able to stop taking it, or had died. But that’s what it meant for Anna Maria
- [Pancreatic cancer patients diagnosed early through screening achieve long-term survival](https://cancerworld.net/pancreatic-cancer-screening-long-term-survival/) - The majority of high-risk patients diagnosed with pancreatic ductal adenocarcinoma (PDAC) while enrolled in a screening programme have stage I disease and can achieve long-term survival. The study, published in Journal of Clinical Oncology (June 15), found that in the US CAPS screening programmes the median survival of patients diagnosed with PDAC was 9.8 years.
- [A call to action: how Poland is stepping up for Ukraine’s cancer patients](https://cancerworld.net/a-call-to-action-poland-stepping-up-ukraine-cancer-patients/) - February 24, 2022. Julia, a lawyer living near Kiev, is counting down the days until her last chemo. After which she will still face surgery and radiation therapy on her way to recovering from breast cancer. Before dawn, she wakes to the sound of monstrous rumbling. It's Russian missiles exploding near her home. "When the
- [Study paves way for better checkpoint inhibitor response prognostication](https://cancerworld.net/study-paves-way-for-better-checkpoint-inhibitor-response-prognostication/) - Use of whole exome sequencing improves prediction of response to immune checkpoint blockade (ICB). The study, published in Nature Communications, 8 July, shows incorporation of the CIRCLE tool, including new genes and pathways identified from whole exome sequencing, leads to improvements in both sensitivity and specificity. “These results suggest that the use of broader diagnostics,
- [Unicorns for Ukraine: mobilising to meet patients’ changing cancer care needs](https://cancerworld.net/unicorns-for-ukraine-mobilising-to-meet-patients-changing-cancer-care-needs/) - When Russia invaded Ukraine on February 24, consultant clinical oncologist Mohammed Hojouj put out a call for help: “Cancers do not stop growing because there is a war. But cancer patients stop being seen as a priority.” The story he told in Cancerworld in early April was about an acute shortage of almost every essential
- [Study defines increased risk of cardiovascular disease among cancer survivors](https://cancerworld.net/study-defines-increased-risk-of-cardiovascular-disease-among-cancer-survivors/) - Adult survivors of cancer have a 37% higher risk of developing cardiovascular disease (CVD) than people without cancer. The study, published in the Journal of the American College of Cardiology, July 5 issue, found cancer survivors had a 52% higher risk of developing heart failure and 22% higher risk of developing stroke than people without
- [Long-term health: is it time to update the priorities of cancer research?](https://cancerworld.net/long-term-health-update-priorities-cancer-research/) - “I was told that cancer was a temporary condition ‒ just get through treatment and things will go back to normal. I quickly realised that this is not true.” Gregory Aune was treated for Hodgkin’s disease when he was 17. That treatment ‒ eight chemotherapy agents and a heavy dose of radiation ‒ saved his
- [Circulating tumour DNA provides early warning of metastatic breast cancer ](https://cancerworld.net/circulating-tumour-dna-early-warning-metastatic-breast-cancer/) - In high-risk hormone receptor positive breast cancer circulating tumour DNA (ctDNA) was identified a median of one year before distant metastasis. The study, published in the Journal of Clinical Oncology (4th June, 2022), represents the first prospective investigation of plasma ctDNA analysis and clinical outcomes in late adjuvant hormone receptor positive breast cancer. “These data
- [Study defines subset of women benefitting from digital breast tomosynthesis](https://cancerworld.net/study-defines-subset-of-women-benefitting-from-digital-breast-tomosynthesis/) - Digital breast tomosynthesis (DBT) offers an advantage over conventional digital mammography in only a tiny percentage of women, who have extremely dense breasts and a high risk of breast cancer. The cohort study, published in JAMA (June 14), found no significant difference for diagnosis of advanced cancers for the great majority of women with dense
- [It’s a CIN: bringing order to the chaos of cancer chromosome instability](https://cancerworld.net/its-a-cin-bringing-order-to-the-chaos-of-cancer-chromosome-instability/) - A new framework has been developed for interpreting complex genetic change patterns seen in cancer chromosomal instability (CIN). The computational analysis study, published in Nature (online 15 June), identifies 17 separate ‘signatures’ across 33 cancer types that could eventually be used as companion diagnostics both for predicting drug response and to identify new targets in
- [GDPR: Why patient control over our health data might not be such a bad thing ](https://cancerworld.net/gdpr-why-patient-control-over-our-health-data-might-not-be-such-a-bad-thing/) - Cancer patients want our data shared and used in ways that could help us, and those like us. Why wouldn’t we? That’s why patients and patient organisations are broadly supportive of EU proposals to create a Cancer Patient Digital Centre, which we hope will not only enable patients and survivors to exchange data and stay
- [India’s Lung Connect shows value of online cancer support in low-income settings](https://cancerworld.net/indias-lung-connect-online-cancer-support-low-income-settings/) - It was April 2020. Just a few weeks earlier, India had imposed a national lockdown – among the harshest in the world. Ramkrishna Bhadhury, 44, a farmer from a small village in Nalikul, West Bengal, was feeling increasingly dejected and frustrated. A lung cancer patient since 2017, he had been on targeted therapy drugs. But
- [Antibody-drug conjugates make their mark at ASCO](https://cancerworld.net/antibody-drug-conjugates-make-their-mark-at-asco/) - Reports of the results of two antibody-drug conjugates (ADCs), one for HER-low metastatic breast cancer, the other for metastatic lung cancer resistant to EGFR inhibitors, highlight the advances being made in this type of treatment. The DESTINY-Breast04 study, presented at ASCO 2022 , and published simultaneously in The New England Journal of Medicine, June 5,
- [Study shines new light on breast cancer's sweet tooth](https://cancerworld.net/new-light-brest-cancer-sweet-tooth/) - Breast cancer cells impair the function of pancreatic islets to make them produce less insulin than required, resulting in higher blood glucose levels in breast cancer patients compared to women without cancer. The study, published in Nature Cell Biology (30th May, 2022), identified the culprit responsible for reprogramming the glucose metabolism of breast cancer patients
- [Preventing burnout: are we too focused on personal resilience?](https://cancerworld.net/preventing-burnout-are-we-too-focused-on-personal-resilience/) - Burnout. That short word barely conveys the dispirited cycle of weariness, negativity and powerlessness health staff experience when high aspirations to help and cure are consumed in an unattainable to-do list. “You're trying your best but nothing's moving and you just feel like in a constant circle,” said one nurse in the UK trying to
- [From sea bed to bedside: Tapping the cancer pharmacy beneath the waves ](https://cancerworld.net/from-sea-bed-to-bedside-tapping-the-cancer-pharmacy-beneath-the-waves/) - Adriana Albini checks out some of the marine life that is already helping cancer patients: why we’ve barely scratched the surface in looking for more marine-derive oncology drugs?
- [Surviving childhood cancer in Africa: helping families stick with the treatment plan is key](https://cancerworld.net/surviving-childhood-cancer-in-africa-helping-families-stick-with-the-treatment-plan-is-key/) - When cancer therapies are hard to afford, require difficult journeys, and leave children feeling worse before they get better, families need support and reasons to believe that sticking with the treatment plan really will pay off. Finding a way to provide that is now a priority in sub-Saharan Africa, where in some countries more than 50% of childhood cancer treatments are abandoned.
- [Angelita Habr-Gama: putting Brazil on the cancer research leaderboard](https://cancerworld.net/angelita-habr-gama-putting-brazil-on-the-cancer-research-leaderboard/) - Brazilian surgeon Angelita Habr-Gama changed the way that lower rectal cancer is treated when she discovered that many patients treated with neoadjuvant chemoradiation for early rectal cancers showed no residual disease and yet were still undergoing abdominal perineal resections. She proposed a ‘watch and wait’ approach, and showed that it is safe to restrict surgery
- [US study suggests colorectal cancer screening should start at age 45](https://cancerworld.net/us-study-suggests-colorectal-cancer-screening-should-start-at-age-45/) - Screening women below the age of 50 for colorectal cancer (CRC) can significantly reduce their risk in comparison to those who have no endoscopic screening or who initiate testing at age 50. The study in JAMA Oncology, published online 5 May 2022, found that, compared to no screening, women who started endoscopy screening before age
- [Cervical cancer: Rebuilding a nation’s broken trust in their screening service](https://cancerworld.net/cervical-cancer-rebuilding-a-nations-broken-trust-in-their-screening-service/) - Lack of transparency combined with a tendency to overhype the level of certainty, contributed to a scandal in cervical cancer screening programme in Ireland.
- [Multicomponent prevention strategy reduces risk of cancer](https://cancerworld.net/multicomponent-prevention-strategy-reduces-risk-of-cancer/) - The combination of high-dose vitamin D, omega-3 and a simple home strength exercise programme (SHEP) reduced the risk of healthy adults aged 70 or older developing cancer by nearly two-thirds. The study, published in Frontiers in Aging, 25 April, showed that while each of the three components provided a small benefit, beneficial effects were much greater
- [What can we expect from mRNA cancer vaccines?](https://cancerworld.net/what-can-we-expect-from-mrna-cancer-vaccines/) - Messenger RNA vaccines turned around Europe’s fight against the Covid pandemic. Less than a year after the first lockdowns were declared, mRNA vaccines got regulatory approval for emergency use, first in people at high-risk from Covid, and later in the broader population. By April 2022, more than 600 million doses of Pfizer/BioNTech’s mRNA-based Covid vaccine
- [Lumpectomy as effective as mastectomy in young breast cancer patients](https://cancerworld.net/lumpectomy-young-breast-cancer-patients/) - Women under 40 with non-metastatic breast cancer experience similar survival regardless of whether they are treated with mastectomy or lumpectomy. The abstract presented at the American Society of Breast Surgeons annual meeting, held in Las Vegas, April 2022, showed that this finding held true across hormone receptor (HR) and HER2 subtypes. The study represents one
- [Multi organ chip could facilitate personalised cancer therapy ](https://cancerworld.net/multi-organ-chip-could-facilitate-personalised-cancer-therapy/) - A ‘plug-and-play’ multi-organ chip, the size of a microscope slide, could be customised for individual cancer patients to determine personalised therapy. The study, published in Nature Biomedical Engineering, reports for the first time the achievement of connecting a range of millimetre-sized engineered tissues (beating heart muscle, metabolising liver, and functioning skin and bone) linked by
- [Sri Lanka cancer care hit by foreign currency crisis](https://cancerworld.net/sri-lanka-cancer-care-hit-by-foreign-currency-crisis/) - Oncology leaders in Sri Lanka are seeking urgent support to help them address an acute shortfall in the drugs they need.
- [100,000 Genomes Project pinpoints new cancer genetic culprits](https://cancerworld.net/100000-genomes-project-cancer-genetic-culprits/) - DNA analysis of thousands of tumours in the 100,000 Genomes project has uncovered a ‘treasure trove’ of 58 new mutational signatures causing cancer. The study, published in Science, 21 April, showed that while there are common signatures for cancers arising in the same organ, there are also rare signatures that span different cancers. The investigators
- [IL-6 provides missing link between exercise and colon cancer protection](https://cancerworld.net/il-6-provides-missing-link-between-exercise-and-colon-cancer-protection/) - Interleukin-6 (IL-6) molecules released into the systemic circulation during exercise elicit biological effects limiting colon cancer cell proliferation. The UK study, published in International Journal of Cancer, 7 April, provides a potential mechanism of action explaining how regular physical activity reduces the risk of colon cancer. “Our findings are really exciting because they reveal a
- [CAR T-cell therapy shows efficacy in solid tumours](https://cancerworld.net/car-t-cell-therapy-efficacy-solid-tumours/) - A CAR T-cell therapy first-in-human study demonstrated early signs of efficacy for patients with a range of solid tumours, including testicular and ovarian cancers. The study, presented at the American Academy of Cancer Research (AACR) 2022 Annual Meeting (8-13 April 2022), held in New Orleans, combined two innovative approaches, autologous CAR T-cell therapy and a
- [Pandemics, War, Reconstruction and the Duty of Medicine and Science](https://cancerworld.net/pandemics-war-reconstruction-and-the-duty-of-medicine-and-science/) - “It is sufficiently obvious that the problems of reconstruction following the war will tax the intelligence and good will of mankind to the utmost. It is also certain that mistakes made during this period will have more serious consequences than similar errors in a period of less social plasticity. By the same token, wise
- [Message from a Ukrainian oncologist: Please prioritise my patients ‒ if you don’t who will?](https://cancerworld.net/message-ukrainian-oncologist-prioritise-my-patients/) - A consultant clinical oncologist in Dnipro, appeals to the European cancer community to help Ukraine’s cancer services access a reliable and steady supply of essential cancer drugs.
- [No link between brain tumours and ‘usual’ use of mobile phones](https://cancerworld.net/no-link-between-brain-tumours-and-usual-use-of-mobile-phones/) - ‘Usual’ use of mobile phones does not increase the incidence of brain tumours. The prospective study, published in the Journal of the National Cancer Institute, 30 March 2022, found no statistically significant associations between ‘ever’ users and ‘never’ users of mobile phones for all brain tumours, and for the subtypes gliomas, meningiomas, pituitary tumours and
- [Developing palliative care: new WHO guidance helps countries tailor their own path](https://cancerworld.net/developing-palliative-care-new-who-guidance-helps-countries-tailor-their-own-path/) - Countries seeking to develop sustainable, accessible, high-quality palliative care services can now find guidance and resources to help them tailor solutions.
- [Global elimination: securing a future free from cervical cancer](https://cancerworld.net/global-elimination-cervical-cancer/) - We may have the chance to eliminate a major cause of cancer deaths among women with cervical cancer, and others caused by the HPV virus.
- [Colorectal cancer linked to lifetime of excess weight](https://cancerworld.net/colorectal-cancer-linked-to-life-time-of-excess-weight/) - Cumulative lifetime exposure to excess weight accounts for a larger share of Colorectal cancer (CRC) risk than previously appreciated. The German study, published in JAMA Oncology, 17 March, demonstrates the importance of characterizing long-term exposure to weight gain and making weight loss a public health priority. “The observed associations suggest that having overweight or obesity
- [Radiologists urged to report breast arterial calcification for CVD prevention](https://cancerworld.net/radiologists-urged-to-report-breast-arterial-calcification-for-cvd-prevention/) - Routine mammograms could be used to provide additional information about women’s risk of cardiovascular disease (CVD). The study, published in ‘Circulation: Cardiovascular imaging’, March 15, found women with breast arterial calcification had a 51% higher risk of heart attacks and strokes than women without calcification. “Our study has moved the needle towards recommending routine assessment
- [Preventing alcohol-related cancers in Europe: lessons from three countries](https://cancerworld.net/preventing-alcohol-related-cancers-in-europe-lessons-from-three-countries/) - Europe has the highest drinking levels in the world, and cancers resulting from drinking alcohol end more lives in Europe than any other alcohol-related cause of death.
- [Do patents encourage or discourage innovation? Intellectual property from ancient Greece to the Covid pandemic](https://cancerworld.net/patents-intellectuale-property-innovation/) - The Covid-19 pandemic has highlighted the tensions of a patent system: Adriana Albini and Francesca Albini look at the history of patents and of the information revolutions that shaped them.
- [No reason to delay cancer immunotherapy following antibiotic use](https://cancerworld.net/no-reason-to-delay-cancer-immunotherapy-following-antibiotic-use/) - Exposure to antibiotics prior to anti-PD-1 antibody treatment had no effect on melanoma outcomes. The French study, reported in the Journal of the National Cancer Institute (published March 7, 2022), found using antibiotics in a large cohort of advanced melanoma patients had no effect on overall survival (OS) or time-to-treatment discontinuation (TTD). “Physicians should not
- [European Cancer Community urged to sign-up to help Ukrainian patients](https://cancerworld.net/european-cancer-community-urged-to-sign-up-to-help-ukrainian-patients/) - The European Cancer Organisation (ECO) and American Society of Clinical Oncology (ASCO) have launched a network to provide an infrastructure to support Ukrainian cancer patients. The Special Network on the Impact of the War in the Ukraine on Cancer, launched 9 March, will function as a hub to direct healthcare workers and patients to real-time
- [Molecular diagnostics and NGS in the clinic: where are we and where do we need to go?](https://cancerworld.net/molecular-diagnostics-and-ngs-in-the-clinic-where-are-we-and-where-do-we-need-to-go/) - Precision medicine in clinical practice: technical, bioinformatics and analytical challenges, collaboration and communication all trying to stay focused on the patient.
- [Crisis in the Ukraine: we can help by doing what we do best](https://cancerworld.net/crisis-in-the-ukraine-we-can-help-by-doing-what-we-do-best/) - Kathy Oliver, patient advocate, explains how she and others in the cancer community are gearing up to the challenge of help those caught up in the humanitarian crisis.
- [The invisible cure. Should we be talking more about cancer surgery?](https://cancerworld.net/the-invisible-cure-should-we-be-talking-more-about-cancer-surgery/) - The best chance of being cured of cancer is through surgery by expert surgeons with a deep knowledge of oncology. Why then are the public, patients and policy makers so focused on drugs, and does it matter? Mass media have an insatiable appetite for stories about cancer. No mystery in that. As readers, viewers and
- [Harmful bacteria play greater role in predicting outcomes of immune checkpoint blockade in melanoma](https://cancerworld.net/harmful-bacteria-predicting-outcomes-immune-checkpoint-blockade-melanoma/) - Harmful gut bacteria may play a greater role than beneficial bacteria in determining efficacy of immune checkpoint blockade in melanoma patients. The study, published in Nature Medicine (28 February), found microbial signatures containing Lachnospiraceae species were connected to favourable anti-programmed cell death protein-1 (anti PD-1) clinical responses, while signatures containing Streptococcaceae species were connected to
- [Precision care: supporting our patients starts with asking them what they want and need](https://cancerworld.net/precision-care-supporting-patients-asking-what-they-want-and-need/) - In the article, Simon Crompton looks at the argument and the prospects for improving the psychosocial support provided by Europe’s cancer care systems.
- [Starting age for MRI breast screening defined for three genetic mutations](https://cancerworld.net/mri-screening-intervals-breast-cancer-mutations/) - Annual magnetic resonance imaging (MRI) starting from age 30 to 35 years followed by combined annual MRI and mammography from age 40 may reduce breast cancer mortality by over 50% for women with ATM, CHEK2, and PALB2 breast cancer genetic mutations. The comparative modelling analysis, published in JAMA Oncology (February 17, 2022), found mammography under
- [A fair chance for women in oncology: we must all insist on change](https://cancerworld.net/a-fair-chance-of-women-in-oncology-we-must-all-insist-on-change/) - Women are under-represented in positions of power and leadership, in scientific and health disciplines across the world. This has been widely recognised for decades, yet efforts to implement the changes required to give women a fair chance have met with limited success. The topic has been covered by many major journals along the years. Nature
- [Aromatase inhibitors better than tamoxifen in premenopausal breast cancer](https://cancerworld.net/aromatase-inhibitors-better-than-tamoxifen-in-premenopausal-breast-cancer/) - Giving aromatase inhibitors (AIs) instead of tamoxifen to premenopausal women with oestrogen receptor positive breast cancer, who have undergone ovarian suppression, significantly reduces risk of recurrence. The study, published in The Lancet Oncology (3 February), found that breast cancer recurrence was reduced by 21% and distant recurrence by 17% among the group receiving AIs. “Our
- [After Covid: AACR call to action to improve cancer care](https://cancerworld.net/after-covid-aacr-call-to-action-to-improve-cancer-care/) - The American Association for Cancer Research (AACR) has issued ‘a call to action’ to build on lessons learnt from Covid-19 to modernize cancer patient care. The ‘ACCR Report on the Impact of Covid-19 on Cancer Research and Patient Care’, published 9 February, revealed while the pandemic had taken its toll on cancer research, prevention and
- [Beating the odds in colorectal cancer](https://cancerworld.net/beating-the-odds-in-colorectal-cancer/) - When the odds are 10 to 1 against you, what, if anything, can be done to help tip the balance in your favour? An interview to an advocate who survived and to his oncologist.
- [Chemobrain: it’s real, it’s troublesome and it deserves more attention](https://cancerworld.net/chemobrain-troublesome-deserves-more-attention/) - The ‘brain fog’ that is so frequently described by people during cancer treatment has yet to be properly defined, let alone measured, understood or alleviated.
- [Study suggests prehabilitation should become standard of care in oesophageal cancer](https://cancerworld.net/prehabilitation-standard-care-oesophageal-cancer/) - Enrolling oesophageal cancer patients in prehabilitation exercise programmes can boost tumour regression during chemotherapy. The small study, published in British Journal of Sports Medicine (online 1 February, 2022), demonstrated improved pathological, radiological and immunological responses to chemotherapy for those in the exercise group. “Numerous biochemical and CT-based parameters differed between the intervention and control groups, suggesting
- [Citizen science: Do your bit for cancer research by playing a game](https://cancerworld.net/your-bit-cancer-research-game/) - Calling all gamers ‒ you can do your bit for advancing cancer research by playing a video game. While this may sound like the ultimate excuse, Spanish investigators really have just launched a smartphone game ‒ the GENIGMA challenge ‒ to help map genomic sequences occurring in cancer cell lines, in order to understand which
- [How we turn lung cancer care into a European success story](https://cancerworld.net/how-we-turn-lung-cancer-care-into-a-european-success-story/) - Seize this opportunity to save lives and money by shifting spending on lung cancer towards well-structured screening programmes: Joanna Chorostowska-Wynimko, tells us how.
- [Study unveils how obesity raises cancer risk](https://cancerworld.net/study-unveils-how-obesity-raises-cancer-risk/) - Obesity-dependent changes in lipid handling in cells may explain why overweight people are more prone to developing cancer than those of normal weights. The study, published in Nature Communications (14 January 2022), identifies higher levels of palmitic acid as the prime culprit, setting in chain a series of negative chemical reactions in obese people. This
- [Sitting and lack of physical activity is a deadly combination in cancer survivors](https://cancerworld.net/sitting-and-lack-of-physical-activity-is-a-deadly-combination-in-cancer-survivors/) - Cancer survivors who combine being inactive (or insufficiently active) with sitting for more than eight hours a day dramatically increase their risk of both cancer specific and overall mortality. The prospective cohort study, published in JAMA Oncology (6 January 2022), found the association of prolonged sitting and low levels of physical activity increased the risk
- [Lung cancer screening: 2022 could be a turning point for Europe](https://cancerworld.net/lung-cancer-screening-2022-could-be-a-turning-point-for-europe/) - Should lung cancer screening be among those added to the current list of others cancer screening that EU member states are recommended to carry out?
- [Academic oncology: women’s careers at high risk for continued inequality](https://cancerworld.net/academic-oncology-womens-careers-high-risk-inequality/) - More than half of women in oncology practice believe their gender adversely affects their prospects for job promotion, especially in academia. The cross-sectional survey, published in JAMA Netw Open (December 30, 2021), found that more academic female oncologists than non-academic female oncologists report a poor sense of belonging in the workplace, with one in five
- [High-fibre diets associated with improved melanoma immunotherapy response](https://cancerworld.net/high-fibre-diets-melanoma-immunotherapy-response/) - Melanoma patients eating greater quantities of fibre-rich foods at the start of checkpoint inhibitor immunotherapy survive longer than patients with insufficient dietary fibre intake. The observational study, published in Science (23 December 2021), reports benefits to be most noticeable among patients who do did not use probiotic supplements. “Our study sheds light on the potential
- [Tackling drug resistance: how our commensal bacteria can hinder or help](https://cancerworld.net/tackling-drug-resistance-how-our-commensal-bacteria-can-hinder-or-help/) - Evidence is emerging about how gut microbes can influence our response to cancer treatments: how this might be used to improve the impact of treatments.
- [Evolution of the doctor-patient relationship: from ancient times to the personalised medicine era](https://cancerworld.net/evolution-of-the-doctor-patient-relationship-from-ancient-times-to-the-personalised-medicine-era/) - The nature of the doctor–patient relationship has gone through various phases in history, based on the changing role of the physician in the community, as well as progress in medicine and increased choices of care, together with better-informed patients. Broadly speaking, the shift in the dynamic between doctor and patient has been from an active‒passive
- [Informal carers play a key role in cancer care: they need and deserve more support](https://cancerworld.net/informal-carers-play-a-key-role-in-cancer-care-they-need-and-deserve-more-support/) - The impact of the care is greater when patients have effective support around them at home, but informal carers often lack the information and support they need.
- [We need a National Cancer Institute! Why Italy should follow the example of the US and France](https://cancerworld.net/we-need-a-national-cancer-institute-why-italy-should-follow-the-example-of-the-us-and-france/) - The genomic revolution and advances in technology are making the pursuit of innovation in oncology increasingly challenging. In Italy, the number and the diversity of the players in the field of experimental and clinical research, and the output of indexed publications by Italian researchers, might be seen as positive and in line what is needed
- [Liver patient advocates to Europe’s cancer community: can we talk?](https://cancerworld.net/liver-patient-advocates-to-europes-cancer-community-can-we-talk/) - Europe’s Beating Cancer plan is galvanising the cancer community behind efforts to tackle rising trends that are currently on course for an almost 25% rise in deaths from cancer across Europe by 2035. We want to help. Liver cancer is not always seen as a prime focus for efforts to reduce mortality rates ‒ it
- [Early exercise helps avoid shoulder problems after breast cancer treatment](https://cancerworld.net/study-supports-exercise-shoulder-breast-cancer/) - Introducing a physiotherapy-led exercise programme following treatment for breast cancer reduces upper limb disability. The UK study, published in The British Medical Journal (online 11 November), found no increase in complications, lymphoedema or adverse events for patients allocated exercise. “Our manualised exercise intervention is suitable for wider implementation in clinical practice,” write the authors, led
- [Antihistamines could improve efficacy of checkpoint inhibitors](https://cancerworld.net/antihistamines-improve-efficacy-checkpoint-inhibitors/) - Over-the-counter antihistamines appear to improve outcomes for cancer patients treated with checkpoint inhibitors. The study, reported in Cancer Cell (published online 24 November), found that melanoma and lung cancer patients taking antihistamines targeting the H1 receptor during anti-PD-1/PD-L1 treatment achieved statistically significant reductions in mortality compared with age, sex, or stage-matched patients not taking antihistamines.
- [Liver cancer: how Europe can halt the rising death toll](https://cancerworld.net/liver-cancer-how-europe-can-halt-the-rising-death-toll/) - Liver cancer is among the most deadly of them all, and rates are steadily rising across Europe due to its association with obesity as well as alcohol.
- [Drugs shortages: ‘We parents of children with cancer are too exhausted to protest’](https://cancerworld.net/drugs-shortages-romania/) - Almost 15 years after joining the EU, Romanians diagnosed with cancer still lack reliable access to many essential cytotoxic therapies.
- [Cancer and fertility preservation: it can be done… Can’t it?](https://cancerworld.net/cancer-and-fertility-preservation-it-can-be-done-cant-it/) - A lot can be done to ensure cancer treatment does not end a woman’s chances of having children, but only if she gets the right information and can access the right services in good time.
- [Study provides insights into long-term effects of childhood cancers](https://cancerworld.net/study-provides-insights-into-long-term-effects-of-childhood-cancers/) - People surviving childhood cancers have a higher risk of other morbidities as they grow older. The study, published online The Lancet Regional Health-Europe (14 November), found that a greater burden of disease was experienced by patients receiving combined treatment with chemotherapy and radiotherapy as well as those from the most deprived areas. “We believe that
- [Ending cancer service delays and backlogs: voices from the frontline](https://cancerworld.net/ending-cancer-service-delays-and-backlogs/) - Pandemic-related delays and backlogs in cancer diagnosis, screening and treatments can be rapidly addressed if health services invest now in data systems that monitor needs and resources, together with innovative ways to meet that need. This was the key message coming from the 2021 Summit of the European Cancer Organisation, November 17‒18, which heard from
- [North and South ‒ learning faster means learning together](https://cancerworld.net/north-and-south-learning-faster-together/) - When you look at the vast waiting area in Mumbai’s world leading Tata Memorial Cancer Hospital, pictured above, what do you see? A crowded chaotic scene where sick patients and their relatives sit around for hours, waiting, hoping for someone to call their name? That’s certainly part of the story, but as Canadian oncologist and
- [Systematic review fills knowledge gaps about metastatic breast cancer](https://cancerworld.net/systematic-review-fills-knowledge-gaps-about-metastatic-breast-cancer/) - In breast cancer the risk of metastasis is higher among women diagnosed at a younger age, those with larger tumours at diagnosis and those with luminal B breast cancer. The study, abstract 0R-91, presented at the Advanced Breast Cancer Sixth International Consensus Conference, held virtually 4-6 November, represents the first global systematic review and meta-analysis to
- [Study challenges dogma that RCC is biologically radioresistant](https://cancerworld.net/study-challenges-dogma-that-rcc-is-biologically-radioresistant/) - Stereotactic body radiation therapy (SBRT) represents a safe and effective non-invasive treatment for oligometastatic renal cell carcinoma (RCC). The study, published in Lancet Oncology, supports sequential radiotherapy as an alternative treatment option to systemic therapy for oligometastatic renal cell carcinoma. “These findings are exiting because we’re challenging the dogma in radiation oncology that RCC is
- [Bridging the Age Gap in Breast Cancer: A treatment selection tool for the over-70s](https://cancerworld.net/bridging-the-age-gap-in-breast-cancer-chemotherapy-and-quality-of-life/) - Q. Surgery tends to be a bigger issue for older people, and physicians need reliable guidance on who is likely to benefit and who could be harmed. You looked at selection practices and outcomes at 56 breast units across the UK. What did you find? A. The Bridging the Age Gap in Breast Cancer study
- [Atlas provides ‘one-stop shop’ for myeloma care information across Europe](https://cancerworld.net/atlas-provides-one-stop-shop-for-myeloma-care-information-across-europe/) - Myeloma Patients Europe (MPE) has launched an overview of myeloma and AL amyloidosis treatment inequalities across Europe. The Myeloma Access Atlas, released 19 October, is a platform which has been developed to provide a ‘one-stop’ shop mapping national availability of myeloma and AL amyloidosis drugs in both EU and non-EU European countries, to provide data
- [Most basic cancer drugs remain inaccessible in low- and lower-middle-income countries](https://cancerworld.net/most-basic-cancer-drugs-remain-inaccessible-in-low-and-lower-middle-income-countries/) - Despite being available for more than 20 years, basic cancer drugs found to be most effective against the disease can still not be accessed by patients in most low- and lower-middle-income countries according to a new study. The paper, published in the Lancet Oncology, presents the findings of a questionnaire sent to oncologists from a
- [When your patient tells you they’re still not better, please accept what they say](https://cancerworld.net/when-your-patient-tells-you-theyre-still-not-better-please-accept-what-they-say/) - “A staggeringly high number of patients still suffer from significant health issues years after being declared disease free.” The words of Dorothy Keefe, head of Australia’s national cancer agency and chair of the 2021 ESMO Congress supportive and palliative care track, may have come as a surprise, maybe even a shock, to many oncologists. To
- [What’s new in lung and colorectal cancer? reports from ESMO 2021](https://cancerworld.net/whats-new-in-lung-and-colorectal-cancer-reports-from-esmo-2021/) - New research findings presented at ESMO 2021 show progress in adjuvant treatment for non-small-cell lung cancer (NSCLC), a novel inhibitor for HER2+ NSCLC patients, and the latest from the FOCUS 4 adaptive, molecularly stratified, umbrella trial platform, set up to evaluate new treatments for patients with metastatic colorectal cancer. Progress in adjuvant immunotherapy for early-stage
- [Dexamethasone helps cancer patients with non-immunogenic tumours survive longer after surgery](https://cancerworld.net/dexamethasone-non-immunogenic-tumours-survive/) - Patients with non-immunogenic cancers, such as breast and gynaecological cancers, who are given the anti-nausea drug dexamethasone during surgery survive longer. The study, abstract 4224, presented at the Anesthesiology 2021 annual meeting, held October 8 to 12, San Diego, found that the risk of dying within 90 days after cancer surgery was 32% lower in
- [Surviving childhood cancer: how we standardise care across Europe](https://cancerworld.net/surviving-childhood-cancer-how-we-standardise-care-across-europe/) - The article explore Europe's disparities in care provided to young cancer patients, and the efforts being made to move towards common protocols and standards.
- [The development of organoids for cancer research: an ode to the scientific method](https://cancerworld.net/the-development-of-organoids-for-cancer-research-an-ode-to-the-scientific-method/) - Mini-organs, grown from human tissue in the lab, are much more reliable than classical cell line and animal models for learning how diseases like cancer develop and can best be prevented and treated.
- [What’s new in supportive care? presentations from ESMO 2021](https://cancerworld.net/whats-new-in-supportive-care-presentations-from-esmo-2021/) - Supportive care studies presented at ESMO Congress 2021 highlight the urgent need for survivors to get more support to tackle long-term symptoms and for doctors and patients to get up to date information in a fast-changing oncology landscape. The need for clinicians to do their utmost to avoid cancer patients discontinuing treatment after Covid-19 is
- [Round-up of prostate and breast cancer studies from ESMO 2021 ](https://cancerworld.net/round-up-of-prostate-and-breast-cancer-studies-from-esmo-2021/) - The 2021 Congress of the European Society for Medical Oncology (ESMO), held 16‒21 September, featured studies that are likely to impact a broad spectrum of clinical practice. We summarise some of the findings that could change treatments for two of the most common cancer types ‒ breast and prostate. In prostate cancer, the PEACE-1 and
- [Cancer-related fatigue: Might research into long-Covid help find causes and cures?](https://cancerworld.net/cancer-related-fatigue-might-research-into-long-covid-help-find-causes-and-cures/) - The post cancer chronic fatigue condition might finally get the attention it needs due to the surge of interest and funding currently being poured into understanding long-Covid.
- [Guiding principles for developing European comprehensive cancer networks proposed](https://cancerworld.net/guiding-principles-for-developing-european-comprehensive-cancer-networks-proposed/) - The European Cancer Organisation and Organisation of European Cancer Institutes have put forward key principles to guide the development of a European Network of Comprehensive Cancer Centres. In a position paper published on September 8th, they set out seven recommendations they argue will be key to implementing EU policies on developing and improving Europe’s infrastructure for
- [Cancer World Editor heads new AACR cancer prevention working group](https://cancerworld.net/cancer-world-editor-heads-new-aacr-prevention-working-group/) - Adriana Albini, Editor in Chief of Cancer World, has been appointed Chair of the new Cancer Prevention Working Group (CPWG) of the American Association for Cancer Research (AACR). “I’m so happy and honoured to have this responsibility, and with the CPWG steering committee hope to be able to make a real difference to advances in
- [Low risk prostate cancer: real-world data reveals high rates of switching from surveillance to treatment](https://cancerworld.net/low-risk-prostate-cancer-real-world-data-reveals-high-rates-of-switching-from-surveillance-to-treatment/) - Over half of men initially managed with active surveillance (AS) for ‘low risk’ prostate cancer switch within four years to definitive treatments (e.g., surgery or radiation therapy). The Canadian study, published in Urology, (20 August) provides real-world data on uptake and discontinuation of AS, as well as exploring factors influencing likelihood of treatment switching. Active
- [Careers of women in oncology hit by Covid-19 pandemic](https://cancerworld.net/careers-of-women-in-oncology-hit-by-covid-19-pandemic/) - The pandemic has seen the careers of female physicians working in oncology suffer as they have taken on more domestic responsibilities during lockdowns. Recent studies have indicated the trend may be global and long lasting. A new paper published in JCO Global Oncology showed that the pandemic had an adverse impact on careers on female
- [Blood pressure drugs improve survival in colorectal cancer](https://cancerworld.net/blood-pressure-drugs-improve-survival-in-colorectal-cancer/) - Common Blood pressure drugs may improve survival in colorectal cancer (CRC). The study, published in Cancer Medicine, (August issue), showed use of Angiotensin Converting Enzyme (ACE) inhibitors, beta blockers and thiazide diuretics were all associated with decreased cancer specific mortality. Furthermore, the investigators found associations between adherence to antihypertensive (AH) medications and cancer specific survival.
- [Louis Denis: one of urology’s most influential and patient-facing physicians](https://cancerworld.net/louis-denis-one-of-urologys-most-influential-and-patient-facing-physicians/) - 20th January 1933 ‒ 28th July 2021 When Louis Denis described himself as a “free thinker”, as he often did, the statement went beyond a vague assertion of independence from dogma and lazy thinking. It was an agenda for action in medicine. Impressive lists of academic positions, clinical and administrative seniority and research contribution –
- [Does the ketogenic diet have a role in treating cancer?](https://cancerworld.net/does-the-ketogenic-diet-have-a-role-in-treating-cancer/) - The potential role of the ketogenic diet fighting cancer has attracted particular attention in recent years. Rachel Brazil looks at the rationale and evidence for its use.
- [Michael Peckham – the artist-oncologist who helped shape our world](https://cancerworld.net/michael-peckham-the-artist-oncologist-who-helped-shape-our-world/) - Not all clinicians choose to look beyond doing their best for their patients to learn about the science behind the disease and play a role in progressing treatments. Fewer still are the successful clinician scientists who choose to look beyond that work to help shape an environment in which medical research and education can thrive.
- [In memoriam Louis Denis](https://cancerworld.net/in-memoriam-louis-denis/) - We remember with immense fondness Louis Denis, a great urologist and patient advocate, and a warm, funny and kind human being, who died on July 21 2021. Louis was among the ‘founding fathers’ of the European School of Oncology. His grasp of the complexities of managing prostate cancer, his unrelenting focus on what matters to
- [Cancer community fights back against Covid-19 related delays](https://cancerworld.net/cancer-community-fights-back-against-covid-19-related-delays/) - The European Cancer Organisation is making materials available to download in 30 different languages to help advocates across Europe lobby national governments to tackle the Covid-19 threat to cancer services in their own countries. The European Time to Act campaign, first launched in April 2021, believes that one million cancer patients across Europe are currently
- [How race to track mystery gene with links to three cancers saved millions](https://cancerworld.net/how-race-to-track-mystery-gene-with-links-to-three-cancers-saved-millions/) - Ten years ago, Tony Herbert developed a lump on the right side of his chest. The clump of tissue grew and became painful and he was tested for breast cancer. The result was positive. “I had surgery and chemotherapy and that worked,” he says. But how had Herbert managed to develop a condition that is
- [The right to health in Latin America: feeling worthy of cancer treatment](https://cancerworld.net/the-right-to-health-in-latin-america-feeling-worthy-of-cancer-treatment/) - Inequalities influence not only access to cancer care but also patients’ perceptions of their right to choose between treatment options and their expectations of receiving quality care. Researchers evaluating how countries in the Americas design their cancer control policies have found that inequality issues are going unaddressed. A study published in Lancet Global Health found that
- [Decolonising cancer research: why it matters, what can be done](https://cancerworld.net/decolonising-cancer-research-why-it-matters-what-can-be-done/) - To improve survival and quality of life, cancer research has to focusing on the needs of communities that have high cancer burdens and low access to effective diagnosis and treatment options.
- [Addressing social needs may help cancer outcomes](https://cancerworld.net/addressing-social-needs-may-help-cancer-outcomes/) - Identifying social needs of cancer patients and developing interventions to mitigate them could improve health outcomes. The survey-based study, published in Cancer (12 July), found unmet social needs in gynaecological cancers were associated with emergency room visits, hospital admissions and treatment interruptions. Social determinants of health (SDOH) have been defined by the World Health Organisation
- [Aspirin cuts risk of death from a wide range of cancers](https://cancerworld.net/aspirin-cuts-risk-of-death-from-a-wide-range-of-cancers/) - Taking aspirin together with cancer treatment results in reductions in death from cancer and all-cause mortality, both by around one fifth. The meta-analysis, published in ecancermedicalscience, (online 2 July), demonstrates benefits for aspirin across a range of cancers and shows fatal bleeding adverse effects to be rare. “We judge that the body of evidence now
- [Tailored exercise: a key element in personalised treatments and prevention](https://cancerworld.net/tailored-exercise-a-key-element-in-personalised-treatments-and-prevention/) - Research shows the exercise health benefits and impact on multiple types of cancer, across prevention, treatment and survivorship settings.
- [Lung cancer screening: time to act on the evidence](https://cancerworld.net/lung-cancer-screening-time-to-act-on-the-evidence/) - Janet Fricker looks at the evidence supporting lung cancer screening and at the questions regions and countries need to address to develop screening programmes.
- [Heart failure may be oncogenic, statins could reduce cancer risk](https://cancerworld.net/heart-failure-may-be-oncogenic-statins-could-reduce-cancer-risk/) - Two studies highlight the relationship between heart failure and cancer, showing people with heart failure are more likely to develop cancer, and that statins may reduce that risk. The first study, published in ESC Heart Failure (28 June 2021), found heart failure patients were 76% more likely to develop cancer than those without heart failure; while the
- [Bella Kaufman: a rare combination of humanity and morality](https://cancerworld.net/bella-kaufman-a-rare-combination-of-humanity-and-morality/) - Bella Kaufman had great compassion for all cancer patients – but on one in particular she was a bit tough. “Why am I so extra strict with myself?” she asked. “I have a non-evidence based fear of treatment disruption. I don’t reduce the dosage. I don’t split. I don’t space it out. I don’t skip…
- [Cancer trials interruption in Latin America halts treatment for many](https://cancerworld.net/cancer-trials-interruption-in-latin-america-halts-treatment-for-many/) - The interruption of cancer clinical trials across Latin America due to the COVID-19 pandemic is threatening the treatment of thousands of patients in the public health system. A JCO Global Oncology study, conducted by the Latin American Cooperative Oncology Group (LACOG), showed temporary and complete interruptions of clinical cancer trials in 90 research sites across
- [Innovations in supportive care: cancer treatment side effects](https://cancerworld.net/innovations-in-supportive-care-cancer-treatment-side-effects/) - Avoiding damage to healthy cells from treatments designed to kill or halt proliferation of cancer cells is not easy, but the pay-off to patients is enormous.
- [Advance Care Planning increases hope](https://cancerworld.net/advance-care-planning-increases-hope/) - Hope for cancer patients may be increased by engaging in advanced care planning (ACP). The study, abstract 12029, presented in a poster session at ASCO, which took place online June 4-8, found that hope was significantly higher among patients who had engaged in end-of-life (EOL) conversations and completed a living will or advance directive. “Hope
- [ACE inhibitor protects against cardiotoxicity](https://cancerworld.net/ace-inhibitor-protects-against-cardiotoxicity/) - In HER2 breast cancer, concurrent use of the ACE inhibitor lisinopril with trastuzumab-anthracyclines benefits left ventricular ejection fraction (LVEF). The study, abstract 509, presented in a poster session at the ASCO meeting, June 4-8, found breast cancer patients treated with trastuzumab plus anthracyclines experienced greater LVEF adverse effects than those using trastuzumab alone. Trastuzumab has
- [Angelo Di Leo leaves a living legacy of quality care and research excellence](https://cancerworld.net/angelo-di-leo-leaves-a-living-legacy-of-quality-care-and-research-excellence/) - Future generations of trials must abandon [the traditional] method of patient selection and define eligibility by tumor biology… The era of breast cancer as a homogenous disease is no more. (Ode to a past Emperor, editorial by Angelo Di Leo and Catherine Oakman, JCO 2010) Angelo Di Leo, who died on 13 June, at only 58
- [Trust me: I’m a surgical oncologist!](https://cancerworld.net/trust-me-im-a-trained-surgical-oncologist/) - Cancer patients need confidence that their surgeon understands cancer and all treatment options, as well as having technical expertise in the often complex procedure they will be performing.
- [Returning to ‘normal’ and beating cancer in Europe 2021](https://cancerworld.net/returning-to-normal-and-beating-cancer-in-europe-2021/) - An ageing population, environmental factors, infectious agents, and lifestyle changes all add to the rising impact of cancer on our lives. If nothing is done, cancer will soon become the leading cause of death in Europe. A comprehensive collaboration across all sectors could reverse this rapidly rising trend. Up to four in ten cases of
- [Wake-up call to offer equal access to life-prolonging treatments in metastatic prostate cancer](https://cancerworld.net/equal-access-life-prolonging-treatments-prostate-cancer/) - Less than one third of men with metastatic castration-sensitive prostate cancer (mCSPC) received established treatment intensification by 2018 that had been demonstrated to extend survival. The US study evaluating real-world utilization of advanced therapies, abstract 5073, released in advance of the forthcoming ASCO meeting, taking place online June 4-8, furthermore revealed concerning data on racial
- [Study provides motivation for European policy makers to implement comprehensive tobacco control](https://cancerworld.net/study-provides-motivation-for-european-policy-makers-to-implement-comprehensive-tobacco-control/) - Fully implementing tobacco control policies across Europe would avoid an estimated 1.65 million lung cancer cases over the next 20 years. The modelling study, published in the May issue of The Lancet Regional Health-Europe, found the largest proportion of lung cancer cases could be prevented in Austria, followed by Germany and Luxembourg. Today 31st May
- [Gordon McVie 1945–2021: a lifetime dedicated to defeating cancer](https://cancerworld.net/prof-gordon-mcvie-1945-2021/) - Gordon McVie passed away on January 20th after a lifetime of pioneering contributions to the cause of defeating cancer: as clinician, researcher, manager, advocate and educator. He was a formidable presence on the UK and European stage, driven by a conviction that science can and will defeat cancer; quick to spot and embrace new opportunities;
- [Pain relief is a right: building confidence in opioid use in oncology](https://cancerworld.net/pain-relief-is-a-right-building-confidence-in-opioid-use-in-oncology/) - A talks with experts in palliating cancer pain about how, in many countries, attitudes have become a bigger barrier than red tape.
- [Fit, susceptible, or frail? Updated recommendations for managing breast cancer in older people](https://cancerworld.net/updated-recommendations-breast-cancer-older/) - Management of breast cancer in older women should include routine use of geriatric assessments. Recommendations from an updated multidisciplinary taskforce, which includes members of the European Society of Breast Cancer Specialists and International Society of Geriatric Oncology, published in Lancet Oncology (14 May), underline the importance of considering heterogeneity in older breast cancer patients. The
- [Ovarian cancer population screening study signals need for additional biomarkers](https://cancerworld.net/ovarian-cancer-population-screening-study-signals-need-for-additional-biomarkers/) - Annual screening for ovarian cancer detects cancer earlier but does not save lives, concludes the largest ovarian cancer screening trial up to now. On the basis of the UK study, published in The Lancet (13th May 2021), general population screening for ovarian cancer cannot be recommended. The study, investigators say, highlights the importance of requiring
- [Mike Morrissey: At your service](https://cancerworld.net/mike-morrissey-at-your-service/) - Mike Morrissey's approach to working with Europe’s professional and patient advocacy groups to help develop effective ways to collaborate to get their voices heard.
- [Study suggests tackling loneliness could help reduce cancer in middle-aged men](https://cancerworld.net/study-suggests-tackling-loneliness-could-help-reduce-cancer-in-middle-aged-men/) - Loneliness among middle-aged men is associated with increased risks of developing cancer. The longitudinal Finnish study, published in the May issue of Psychiatry Research, additionally found mortality was higher among male cancer patients who were unmarried, widowed or divorced than those in relationships. “Our results underline the findings of the earlier studies that loneliness should
- [Breast cancer surgery should be a job for certified specialists – an appeal](https://cancerworld.net/breast-cancer-surgery-should-be-a-job-for-certified-specialists/) - Many women, knowing they need surgery for breast cancer, are afraid of looking disfigured after their operation. The question, on day one, is how and where to find a specialist breast surgeon. Personal recommendations cannot always be relied on. Often, we end up in the hands of surgeons who lack the knowledge and expertise needed
- [A Global Licence for Breast Surgery – my call to action!](https://cancerworld.net/a-global-licence-for-breast-surgery/) - I am a two-time breast cancer survivor. My diseased breast, which had a triple-negative collision tumour, was partially removed and immediately reconstructed with autologous tissue followed by chemotherapy and radiation. Exactly five years later a recurrence was diagnosed and the tumour was successfully removed again. I am lucky to have received top-quality health care. However
- [Drug repurposing approaches offer hope for squamous cell carcinoma and Alzheimer’s disease](https://cancerworld.net/drug-repurposing-offers-hope-for-squamous-cell-carcinoma-and-alzheimers-disease/) - Two recent publications highlight the growing interest of drug repurposing in oncology. A study in Cancer Prevention Research (published online 12 April) shows how dopamine can stop the development and progression of ultraviolet B (UVB)-induced precancerous squamous skin cancers; while a study in Alzheimer’s Dementia (published online 17 March) reports that the cancer drug sargramostim
- [Manfred Weber – chair of the European Parliament EPP group](https://cancerworld.net/manfred-weber-chair-of-the-european-parliament-epp-group/) - Alberto Costa: How was Europe’s Beating Cancer Plan conceived and designed? Manfred Weber: The European Union is ultimately there to make the lives of Europeans better. For European politicians, this is our end goal. We know that with less than 10% of the world population, Europe has 25% of the cancer burden, which may reach
- [Prostate cancer: new leads for deterring progression](https://cancerworld.net/prostate-cancer-new-leads-for-deterring-progression/) - New evidence indicates that living healthier lifestyles could almost halve the risk of prostate cancer progressing to a lethal form among men at genetically high risk.
- [Immunotherapy plus chemo: benefits in lung cancer neoadjuvant treatment](https://cancerworld.net/immunotherapy-plus-chemo-for-advance-in-lung-cancer-neoadjuvant-treatment/) - Adding a check point inhibitor to chemotherapy as neoadjuvant treatment for resectable non-small cell lung cancer (NSCLC) produced significant improvements of pathological complete response (pCR) in comparison to chemotherapy alone. The CheckMate-816 study, presented at the American Association for Cancer Research (AACR) Annual Meeting, held virtually April 10-15 2021, represents the first randomized Phase 3
- [Machine learning holds key to personalised cancer drugs](https://cancerworld.net/machine-learning-holds-key-to-personalised-cancer-drugs/) - Researchers have developed a machine learning (ML) algorithm that can be used to rank the effectiveness of different drugs in reducing cancer cell growth for individual patients. In Nature Communications (25 March 2021), the UK investigators report the feasibility of their new Drug Ranking Using Machine Learning (DRUML) technology, which predicted drug responses in independent
- [Older, frail patients are still being let down by the regulators](https://cancerworld.net/older-frail-patients-are-still-being-let-down-by-the-regulators/) - Hans Wildiers is frustrated. “This drug is well-tolerated in older persons – this is a very frequent conclusion in publications. And it is often not a correct conclusion,” says the immediate past president of SIOG, the International Society of Geriatric Oncology, who works at the University Hospitals Leuven, in Belgium. Half of all new cancer
- [Not too little, not too much… a lesson for cancer prevention from ancient civilisations ](https://cancerworld.net/not-too-little-not-too-much-a-lesson-for-cancer-prevention-from-ancient-civilisations/) - Unhealthy diet and obesity are rapidly becoming a major cause of preventable cancers: 2000 years ago Hippocrates first preached the health benefits of moderation in what we eat.
- [Beating cancer is complex – our messaging must be clear](https://cancerworld.net/beating-cancer-is-complex-our-messaging-must-be-clear/) - With the launch of Europe’s Beating Cancer Plan, the Cancer Mission, and the EU4Health programme, the European Commission has offered an ambitious vision, a road map and momentum.
- [EMA at 25: learning more from cancer patients](https://cancerworld.net/ema-at-25-learning-more-from-cancer-patients/) - To mark its 25th anniversary, European Medicines Agency invited leading voices from parts of the cancer community to share their perspectives on patient-focused cancer drug development.
- [Oncolytic viruses – a new wave of therapeutic possibilities](https://cancerworld.net/oncolytic-viruses-a-new-wave-of-therapeutic-possibilities/) - The lack of long-lasting adverse effects, and synergy with immunotherapy combinations, make oncolytic viral therapies an attractive therapeutic tool.
- [Are tumour-agnostic approaches the future for oncology?](https://cancerworld.net/are-tumour-agnostic-approaches-the-future-for-oncology/) - Never mind what or where it is, just look for the target: we ask whether this will be the new paradigm for treating cancer and explore the challenges this approach raises.
- [How to make precision drugs that work better](https://cancerworld.net/how-to-make-precision-drugs-that-work-better/) - Six lessons from the development of the first targeted anti-cancer therapy Tamoxifen famously started life as a failed contraceptive, developed by ICI (now Astra Zeneca), but with the fatal flaw that it increased ovulation rather than suppressing it. It’s a story sometimes told to show how discoveries can come from unexpected quarters and that scientific
- [Indian cancer care struggles with pandemic of late diagnoses and delayed treatments](https://cancerworld.net/indian-cancer-care-struggles-with-pandemic-of-late-diagnoses-and-delayed-treatments/) - An average cancer patient in India usually seeks treatment three months after the symptoms appear. Due to lack of transport facilities and fear of contracting coronavirus, the time to seek care during the COVID-19 pandemic has doubled, with patients finally going to see a doctor six to seven months after the appearance of symptoms, affecting
- [Cancer-associated thrombosis: awareness and action can save many lives](https://cancerworld.net/cancer-associated-thrombosis-awareness-and-action-can-save-many-lives/) - Cancer and the effects of treatment increase the risk of blood clots considerably, with venous thromboembolism being the second most common cause of death in patients with cancer.
- [Rapid palliation of bone mets: it’s effective and easy, so why aren’t we all doing it?](https://cancerworld.net/rapid-palliation-of-bone-mets-its-effective-and-easy-so-why-arent-we-all-doing-it/) - Palliative radiotherapy of painful bone metastases is a highly effective way to support quality of life for the many people who live with incurable cancers that have spread to the bone.
- [Delivering cancer care during the pandemic: lessons from the ‘first wave’](https://cancerworld.net/delivering-cancer-care-during-the-pandemic-lessons-from-the-first-wave/) - How the COVID-19 pandemic ‘first wave’ impacted on the delivery of cancer care: the responses to the Cancer World survey of clinicians on what went well, and what we need to do better.
- [Smoke without fire? Should cancer of unknown primary be treated as a separate disease?](https://cancerworld.net/smoke-without-fire-should-cancer-of-unknown-primary-be-treated-as-a-separate-disease/) - Pathology-based treatment approaches are not effective in many cases of CUP due to its elusive biology, we examine the arguments for switching to a tissue-agnostic approach.
- [Raed Al Dieri: Taking pathology from bit part to key player on the European oncology scene](https://cancerworld.net/raed-al-dieri-taking-pathology-from-bit-part-to-key-player-on-the-european-oncology-scene/) - Precision medicine still struggles to make its voice heard at the level of professional oncology societies and cancer policy making and Raed Al Dieri is determined to change all that.
- [Could covid-19 boost interest in drug repurposing in oncology?](https://cancerworld.net/could-covid-19-boost-interest-in-drug-repurposing-in-oncology/) - During the Covid-19 pandemic, a number of approved drug repurposing therapies have been assessed as potential treatments against the virus and its effects.
- [Will artificial intelligence revolutionise cancer therapeutics and care?](https://cancerworld.net/will-artificial-intelligence-revolutionise-cancer-therapeutics-and-care/) - Artificial Intelligence has started to impact oncology, with tools for more-accurate cancer diagnostics, but its role in better interpreting genomic data is still to be realised.
- [Prognostic biomarkers: could they help doctors, patients and families to better navigate the end of life?](https://cancerworld.net/prognostic-biomarkers-could-they-help-doctors-patients-and-families-to-better-navigate-the-end-of-life/) - “We had to explain that the reason she had broken her hip was because she was getting weaker and essentially dying… At that stage knowing whether Mum had days or months left would have been an important factor.” Helen Waddell, talking about her mother Liz Skinsley “I wish we’d had the opportunity to plan our
- [Rare cancer care: Are European Reference Networks delivering on the promise?](https://cancerworld.net/rare-cancer-care-are-european-reference-networks-delivering-on-the-promise/) - Are European Reference Networks fulfilling their mandate to improve the quality of diagnostics and care for patients with rare cancers in post-pandemic Europe?
- [Malignant: Insights into the process of metastasis and how we can stop it](https://cancerworld.net/malignant-insights-into-the-process-of-metastasis-and-how-we-can-stop-it/) - In the majority of cancers it is the metastases and not the primary tumour that prove fatal. Adriana Albini reviews steps in the malignant process and strategies to block it.
- [On a mission to beat cancer](https://cancerworld.net/on-a-mission-to-beat-cancer/) - European Union Cancer Mission (Horizon 2020) initial recommendations are now open for comment and consultation: what should be the priorities?
- [Does it work for my patient? A pragmatic approach to building evidence on clinical effectiveness](https://cancerworld.net/does-it-work-for-my-patient-a-pragmatic-approach-to-building-evidence-on-clinical-effectiveness/) - New cancer therapies need to enter the market with a strategy for developing the evidence that patients and their doctors need to make informed decisions.
- [Guiding career paths from trainee doctor to oncology leader](https://cancerworld.net/guiding-career-paths-trainee-doctor-oncology-leader/) - European School of Oncology opens a 'college' to ensure guidance and support to the young doctors that in Europe are starting out on oncology careers.
- [Contagion: a narrative approach to understanding the psychological and social impact of the pandemic](https://cancerworld.net/contagion-a-narrative-approach-to-understanding-the-psychological-and-social-impact-of-the-pandemic/) - The coronavirus pandemic is so much more than a biological phenomenon: we need to grasp this to effectively address the continuing damage it is doing as we move forward.
- [Delivering the best cancer care during the pandemic](https://cancerworld.net/delivering-the-best-cancer-care-during-the-pandemic/) - The pandemic is here: planning ahead is key to ensuring cancer patients get the best possible treatment and care during the weeks and months ahead.
- [Their fingers on the button: why neglecting radiation therapists is no longer an option](https://cancerworld.net/their-fingers-on-the-button-why-neglecting-radiation-therapists-is-no-longer-an-option/) - Europe’s radiation therapist profession are working hard to ensure training and education but they need support from policy makers and cancer community.
- [Berlin pilot project brings precision care to the peripheries](https://cancerworld.net/berlin-pilot-project-brings-precision-care-to-the-peripheries/) - An innovative network in Germany is giving men with advanced prostate cancer access to cutting-edge precision medicine – even if they live in remote areas.
- [José Baselga: A giant of medical oncology](https://cancerworld.net/jose-baselga-a-giant-of-medical-oncology/) - We remember a great oncology leader who helped shape Europe’s translational and clinical cancer landscape, making it fit for the era of precision medicine.
- [Updated MINDACT results reveal chemotherapy benefit in some breast cancers varies by age](https://cancerworld.net/updated-mindact-results-reveal-chemotherapy-benefit-in-some-breast-cancers-varies-by-age/) - Updated results of the MINDACT trial confirm that women with early-stage breast cancer, who were assessed to be at high clinical but low genomic risk for recurrence, and did not receive chemotherapy, continue to have excellent distant metastasis free survival (DMFS). The latest analysis, conducted at a median follow-up of 8.7 years, which was reported
- [Giorgio Parmiani: Cancer immunology looses a mentor and a pioneer](https://cancerworld.net/giorgio-parmiani-cancer-immunology-looses-a-mentor-and-a-pioneer/) - A personal thought for one of our oncology research leaders, who has just left us: Prof. Giorgio Parmiani, a great scientist and a forerunner in Immunology.
- [Can gene therapy be made to work against solid tumours?](https://cancerworld.net/can-gene-therapy-be-made-to-work-against-solid-tumours/) - A look at some novel approaches in gene therapy technologies that are being trialled in hard-to-treat cancers such as glioblastomas and triple-negative breast cancers.
- [Artificial intelligence for skin cancer diagnosis, from science-fiction to reality](https://cancerworld.net/artificial-intelligence-for-skin-cancer-diagnosis-from-science-fiction-to-reality/) - Dermatology is a candidate for an artificial intelligence-driven revolution: automated screening and diagnosis of skin cancer will become reality, but how and when?
- [Real world data: can we rely on it to shape cancer policies and practice?](https://cancerworld.net/real-world-data-can-we-rely-on-it-to-shape-cancer-policies-and-practice/) - The digital era has opened up huge possibilities for collecting, storing and analysing data: that could allow us to get the best for every patient and for health systems overall.
- [CCC-19 and TERAVOLT studies show strength and limits of research on cancer and COVID-19](https://cancerworld.net/ccc-19-and-teravolt-studies-show-strength-and-limits-of-research-on-cancer-and-covid-19/) - Results can be achieved in a very short time with good collaboration, but disparities in the mortality rate figures point to the need to control for differences in healthcare settings, risk factors and comorbidities.
- [Consequences of the COVID-19 pandemic on cancer patients](https://cancerworld.net/unexpected-consequences-of-the-covid-19-pandemics-on-cancer-patients/) - According to data and estimates, extreme pressure on healthcare systems is impacting heavily on rates of cancer screening and care, which could lead to an increase in mortality rates.
- [MDT meetings: why patient care suffers if I’m not there](https://cancerworld.net/mdt-meetings-why-patient-care-suffers-if-im-not-there/) - Multidisciplinary team meetings should be where the full details of a patient’s cancer diagnosis are discussed by specialists to reach a consensus recommendation for treatment and care.
- [Cancer and COVID-19 took the stage at AACR Annual Meeting](https://cancerworld.net/cancer-and-covid-19-took-the-stage-at-aacr-annual-meeting/) - The first data presented about cancer and Covid-19 show that there are still many questions and that the outcomes can be very different from center to center.
- [Covid-19 pandemic: information and resources to support the cancer care community](https://cancerworld.net/covid-19-pandemic-information-and-resources-to-support-the-cancer-care-community/) - Recommendations on the management of patients and the reorganization of the cancer clinical practice. Here you can find some useful links.
- [Evidence-based medicine and precision medicine – irreconcilable or inseparable? ](https://cancerworld.net/evidence-based-medicine-and-precision-medicine-irreconcilable-or-inseparable/) - How to build an evidence base to inform treatment choices that are tailored to the unique genomic profile of each patient and their disease.
- [How retractions are helping cancer research](https://cancerworld.net/how-retractions-are-helping-cancer-research/) - Retraction Watch is a comprehensive database helping to foster a better quality of research, including in oncology. Interview to science journalist Ivan Oransky.
- [Right drug, wrong patient: here’s how we improve our targeting](https://cancerworld.net/right-drug-wrong-patient-heres-how-we-improve-our-targeting/) - Balkees Abderrahman presents her perspective on why the revolutionary techniques used to investigate cancers have not yet delivered on the promise of the right drug for the right patient.
- [AI will help Cinderella to see herself in the mirror](https://cancerworld.net/ai-will-help-cinderella-to-see-herself-in-the-mirror/) - A Tool in development that will use artificial intelligence to help women predict how they will feel about their body after breast reconstruction surgery.
- [The unique toxicities of CAR-T cell therapy](https://cancerworld.net/the-unique-toxicities-of-car-t-cell-therapy/) - Toxicities related to CAR T cell therapy are very different from the toxic side effects associated with classical chemotherapy or targeted therapy.
- [Tackling resistance to anti-EGFR therapies, from challenges to re-challenge](https://cancerworld.net/tackling-resistance-to-anti-egfr-therapies-from-challenges-to-re-challenge/) - New technologies and innovative approaches can help preventing and overcome innate or acquired resistance to EGFR inhibitors, improving their therapeutic effects.
- [HPV vaccine “lying around” unused in Africa due to pandemic disruption](https://cancerworld.net/hpv-vaccine-lying-around-unused-in-africa-due-to-pandemic-disruption/) - Vaccinations for human papillomavirus (HPV) in Africa are well below World Health Organisation (WHO) targets due to COVID-19 pandemic disruptions. The WHO Africa region target was to have 35 countries introduce the HPV vaccine by 2020, but only 16 countries have been able to meet that target, according to WHO. There is low demand for
- [Association of steroid use with survival in solid tumours](https://cancerworld.net/association-of-steroid-use-with-survival-in-solid-tumours/) - Interview with Fausto Petrelli, oncology unit, asst Bergamo ovest, Treviglio (Italy). Q.Steroids are commonly used in patients with solid tumours for supportive therapy. Your systematic review and metanalysis recently published in European Journal of Cancer seems to question the real usefulness of this approach. Why? A. Steroids have indoubt beneficial effects in cancer patients in
- [The oncologist-patients who share their unique insights ](https://cancerworld.net/the-oncologist-patients-who-share-their-unique-insights/) - “I try not to think about it. However, a few times a day, I have moments of a few seconds when I feel like panic is taking over me. After a while everything passes, but I can't handle it very well.” When Jacek Jassem, Head of the Department of Oncology and Radiotherapy at the Medical
- [Our pathways: advocates provide roadmaps for patients, clinicians and managers](https://cancerworld.net/our-pathways-advocates-provide-roadmaps-for-patients-clinicians-and-managers/) - Patient advocates have a collective understanding of the patient pathway, from the first suspicious symptoms to the realities of life as a survivor, that is unrivalled by any professionals. They also understand better than anyone how valuable that knowledge and experience is to people trying to navigate their way through a new cancer diagnosis. And
- [Cancer caused by occupational exposure needs urgent attention](https://cancerworld.net/cancer-caused-by-occupational-exposure-needs-urgent-attention/) - What is the cancer burden associated with occupational exposure? A new review shows that the question needs urgent attention, given under-reporting and current difficulties in estimating the global burden. The review, in Molecular Oncology, highlights how millions of workers are exposed daily to crystalline silica in mineral dust, diesel engine exhaust emissions, welding fumes and
- [EC probe sets precedent for cancer drug price reduction](https://cancerworld.net/ec-probe-sets-precedent-for-cancer-drug-price-reduction/) - The European Commission (EC) has made commitments offered by Aspen Pharmacare Holding, to reduce prices for six critical cancer medicines by around two thirds, legally binding. In the acceptance agreement (10 February) Aspen will additionally retrospectively reimburse member states by excess amounts paid since 1 October 2019 and ensure continual off-patent medicine supplies for a
- [European vision for universal access to oncology precision medicine biomarker tests](https://cancerworld.net/european-vision-for-universal-access-to-oncology-precision-medicine-biomarker-tests/) - Current access to high quality oncology biomarker testing across Europe is inconsistent and contributes to health inequalities. To address barriers to biomarker testing, the ‘Unlocking the potential of precision medicine in Europe’ report (published February 23 2021) proposes 12 policy recommendations including the short term goal all cancer patients eligible for biomarker-linked therapy should undergo
- [Two studies provide ‘building blocks’ for future advances in pancreatic cancer](https://cancerworld.net/building-blocks-future-advances-pancreatic-cancer/) - Two recently published studies have provided insights into new ways of tackling pancreatic ductal adenocarcinomas (PDACs), a cancer where survival outcomes have made little progress in the past few decades. Approximately 95% of pancreatic malignancies are pancreatic ductal adenocarcinomas (PDACs), which originate in cells lining the ducts transporting intestinal enzymes. With overall 5-year survival rates
- [Natural killers: a new tactical unit joins the cancer immunotherapy brigade](https://cancerworld.net/natural-killers-a-new-tactical-unit-joins-the-cancer-immunotherapy-brigade/) - There was a time when all that oncologists treating solid tumours needed to know about leukocytes was how to measure the damage that cytotoxic drugs inflicted on their patients’ white blood cell count and their capacity to fight off infections. With the introduction of monoclonal antibodies, and more recent molecular discoveries, that is all changing.
- [Immunotherapy toxicities demand a joined up approach from oncologists and organ specialists](https://cancerworld.net/immunotherapy-toxicities-demand-a-joined-up-approach-from-oncologists-and-organ-specialists/) - Adverse effects of cancer therapies have long been at the root of decision making for interventions in all modalities – surgery, radiotherapy and medical – and especially in the latter category of anti-cancer drugs. Most people have heard of some side-effects, often severe, of cytotoxic chemotherapies, but the advent of targeted and biological therapies in
- [Who wouldn’t want to cure 100% of childhood cancers?](https://cancerworld.net/who-wouldnt-want-to-cure-100-of-childhood-cancers/) - More than eight in ten children and young adults diagnosed with cancer now survive their disease, often going on to live long and fulfilling lives. But the serious life-long damage that is inflicted by many treatments is still a bit of a taboo subject. Sophie Fessl hears from parents and survivors who want to see
- [Study brings mass biparametric MRI screening for prostate cancer a step closer](https://cancerworld.net/study-brings-mass-biparametric-mri-screening-for-prostate-cancer-a-step-closer/) - Using biparametric (bp) magnetic resonance imaging (MRI) to screen for prostate cancer identified twice as many clinically significant cancers as standard prostate-specific antigen (PSA) tests. Moreover, the UK study, reported in JAMA Oncology (11 February), found bpMRI improved detection of prostate cancers without leading to unnecessary biopsy or over diagnosis. In contrast, ultrasonography, was found
- [Oncology providers urged to offer healthy life style advice to breast cancer survivors](https://cancerworld.net/oncology-providers-urged-to-offer-healthy-life-style-advice-to-breast-cancer-survivors/) - Breast cancer survivors commonly experience treatment-related factors, such as fatigue, depression and discomfort, presenting barriers to the adoption of healthy life styles. The US questionnaire study, published in the Journal of the Academy of Nutrition and Dietetics (1 February 2021), underscores the need for breast cancer patients to be offered tailored advice on nutrition and
- [World Cancer Day: we commemorate Professor Agim Sallaku](https://cancerworld.net/world-cancer-day-we-commemorate-professor-agim-sallaku/) - Since 2008, rallies around World Cancer Day on the 4th of February, support collective actions for a healthier world without cancer. The current Covid19 pandemic which placed the medical staff in the front line of leading the battle against the virus, is another reminder of their vital role in protecting and keeping us all safe.
- [Studies provide clarity on breast cancer genes for genetic panels](https://cancerworld.net/studies-provide-clarity-on-breast-cancer-genes-for-genetic-panels/) - Two large case control studies have defined eight genes considered useful to include on genetic panels for predicting risk of breast cancer. The two studies, one by The Breast Cancer Association Consortium (BCAC), led by Doug Easton in Cambridge, and the other by U.S. investigators, both published in the New England Journal of Medicine, independently
- [EC publishes route map for tackling cancer](https://cancerworld.net/ec-publishes-route-map-for-tackling-cancer/) - A plan from the European Commission provides a roadmap for Europe to tackle the entire cancer pathway from prevention to improving the quality of life for cancer survivors. The aim of the Europe’s Beating Cancer Plan (published 3 February), accompanied by €4 billion to support the multiple initiatives, is once and for all to turn
- [Chiara Gasparotto – winning the case for better access to radiotherapy](https://cancerworld.net/chiara-gasparotto-winning-the-case-for-better-access-to-radiotherapy/) - A quarter of cancer patients who could benefit from radiotherapy do not receive it. As head of policy and partnerships, Chiara Gasparotto is positioning the European Society for Radiotherapy to make the case for better access and to alert policy makers and the public to the unmet need in their own countries. Peter McIntyre reports.
- [Therapy targeting androgen receptors opens new chapter for hormone driven breast cancers](https://cancerworld.net/therapy-targeting-androgen-receptors-opens-new-chapter-for-hormone-driven-breast-cancers/) - Androgen receptor activation exerts potent antitumour activity in oestrogen receptor positive breast cancer. The international study, published in Nature Medicine (18th January), has important therapeutic implications for women with metastatic breast cancers that are oestrogen receptor positive, including those who have become resistant to current forms of endocrine therapy. “We provide compelling new experimental evidence
- [Thank you virologists! - Nobel Prize spotlights virus-associated cancers](https://cancerworld.net/thank-you-virologists-nobel-prize-spotlights-virus-associated-cancers/) - With the 2020 Nobel Prize going to three scientists who led on the discovery of the hepatitis C virus, Adriana Albini acknowledges the valuable contributions that these and other virologists have made over many decades to advancing our understanding of cancer and boosting efforts to prevent and control the disease. As the world holds its
- [Coffee may protect against prostate cancer](https://cancerworld.net/coffee-may-protect-against-prostate-cancer/) - Drinking several cups of coffee every day may be linked to a lower risk of developing prostate cancer. The meta-analysis study, published in BMJ Open, (11 January) found that each additional daily cup of coffee was associated with a 1% reduction in prostate cancer risk. However, the study should not be considered as giving men
- [Financial burden on older adults with advanced cancer worsens quality of life](https://cancerworld.net/financial-burden-older-adults-advanced-cancer-quality-of-life/) - Among older adults with advanced cancer, those judged to have financial issues experience worse quality of life, with the adverse effects including higher levels of depression, anxiety and distress. The study, reported in JAMA Network Open (published 7 December), highlights that less than half of cancer patients with financial problems have their issues addressed by
- [Integrated imaging opens the way for virtual biopsies](https://cancerworld.net/integrated-imaging-opens-the-way-for-virtual-biopsies/) - Combining computed tomography (CT) scans, spatial radiomic maps, and ultrasound (US) images creates a visual guide that helps doctors perform fewer and more accurate tumour biopsies. The feasibility study, published in European Radiology (14 December), demonstrates how imaging can be used to non-invasively unravel the heterogeneity of ovarian cancer tumours and guide targeted biopsies. The
- [Highlights of 2020 American Society of Hematology (ASH) meeting](https://cancerworld.net/highlights-of-2020-american-society-of-hematology-ash-meeting/) - Like most 2020 meetings the 62nd American Society of Hematology (ASH) Annual Meeting and Exposition, held 5-8 December, was hosted virtually. Due to meticulous planning, the format did not prevent delegates attending the largest gathering of the professional haematology community from undergoing the full conference experience. There was a wide ranging and innovative scientific programme,
- [Cancer survivors at greater risk of subsequent primary cancers](https://cancerworld.net/cancer-survivors-at-greater-risk-of-subsequent-primary-cancers/) - Survivors of adult-onset cancers run a greater risk of developing and dying from subsequent primary cancers (SPCs) than the general population. The retrospective cohort study, reported in JAMA (December 22), found cancers associated with smoking or obesity comprised the majority of the secondary cancers. “These findings reinforce the importance of coordinated efforts by primary care
- [Liquid biopsy for early stage lung cancer moves closer](https://cancerworld.net/liquid-biopsy-for-early-cancer-moves-closer/) - Interview with Christian Rolfo, MD, PhD, MBA, Dr.h.c. director of the Thoracic Medical Oncology and the Early Clinical Trials and Experimental Therapeutics Research Program investigator at the University of Maryland Marlene and Stewart Greenebaum Comprehensive Cancer Center. Q. Your article in Nature Reviews Clinical Oncology (vol 17, September 2020, page 523) reflects on the integrated
- [The cost of cancer in Europe](https://cancerworld.net/the-cost-of-cancer-in-europe/) - Interview with Thomas Hofmarcher, health economist, IHE - The Swedish Institute for Health Economics, Lund, Sweden. Q. Which is the origin of your idea of studying the cost of cancer in Europe? Does the Swedish Institute for Health Economics have a special interest in the topic? A. Our interest in studying this topic goes back over
- [Highlights of 2020 San Antonio Breast Cancer Symposium](https://cancerworld.net/highlights-of-2020-san-antonio-breast-cancer-symposium/) - In 2020, the San Antonio Breast Cancer Symposium (SABCS) co-organised in association with the American Association for Cancer Research (AACR) celebrated its 43rd year as the world’s premier annual breast oncology meeting. Like most conferences, due to the Covid-19 pandemic, for the first time this meeting was hosted as a virtual event. Despite these unique
- [A silver lining: Could changes forced by the pandemic point to better ways to conduct our clinical trials?](https://cancerworld.net/a-silver-lining-could-changes-forced-by-the-pandemic-point-to-better-ways-to-conduct-our-clinical-trials/) - Pragmatic adjustments to trial protocols were seen to be essential during the Covid-19 pandemic to avoid trials being abandoned or delayed. Most changes involved reducing the requirements for travelling to centralised trials centres and reducing the level of reporting requirements. These measures were agreed between trial sponsors, regulators, contract research organisations (CROs) and trial centres
- [Immunotherapy cardiotoxicity higher than previously estimated](https://cancerworld.net/immunotherapy-cardiotoxicity-higher-than-previously-estimated/) - Cancer patients receiving immunotherapy drugs have a much higher incidence of cardiac events than previous estimates from pharmacovigilance data, reports a nationwide Danish registry. The study, published in the European Heart Journal, found patients with lung cancer or malignant melanoma treated with immune checkpoint inhibitor (ICI) therapy have a 7−10% increased risk of cardiac events
- [The sunshine hormone: the many wonders of vitamin D](https://cancerworld.net/the-sunshine-hormone-the-many-wonders-of-vitamin-d/) - Vitamin D has drawn much scientific interest and media coverage in recent years, and increasingly so in 2020, when a link was found between vitamin D deficiency and Covid-19. This is a very unusual vitamin, in that it behaves both as a hormone and a vitamin – our skin produces it through exposure to sunlight
- [The ABC Global Alliance launch a Global campaign to raise awareness about advanced breast cancer](https://cancerworld.net/the-abc-global-alliance-launch-a-global-campaign-to-raise-awareness-about-advanced-breast-cancer/) - There are over two million new cases of breast cancer a year in the world and 0.6 million deaths. About a third of all early breast cancer cases will become metastatic even with the best care, and the average overall survival for these patients is around three years. The ABC Global Alliance, a multi-stakeholder platform
- [Telling stories about cancer ‒ six award-winning journalists show how it’s done](https://cancerworld.net/telling-stories-about-cancer-five-award-winning-journalists-show-how-its-done/) - We often talk about the need to break down ‘silos’ in cancer care – to view treatment, care and research holistically, collaborating around patient needs. Who would have thought that journalists would show clinicians the way? Of all the changes we’ve seen in cancer reporting since the European School of Oncology’s Cancer Journalism Award was
- [Gut microbiome positively influences abiraterone response in prostate cancer](https://cancerworld.net/gut-microbiome-is-involved-in-abiraterone-response-in-prostate-cancer/) - Abiraterone acetate (AA), an agent used in castrate-resistant prostate cancer, promotes a shift towards health-associated, anti-inflammatory gut commensal bacteria, finds a study in Nature Communications. “These findings clearly demonstrate that the gut microbiome is playing a role in treatment response,” says Jeremy Burton, the study lead investigator from the University of Western Ontario, London, Canada.
- [COVID – are cancer patients being protected?](https://cancerworld.net/covid-are-cancer-patients-being-protected/) - This is a particularly worrying time for people going through chemotherapy and other treatments that suppress the immune system. So what advice is being offered by oncology departments and what extra measures are being taken to keep their patients safe? We hear from the partner of a woman who is being treated for ovarian cancer
- [Delivering cancer care during the pandemic in Europe’s most overstretched health system](https://cancerworld.net/delivering-cancer-care-during-the-pandemic-in-europes-most-overstretched-health-system/) - In a 2016 Voices post, Geta Roman wrote about the daily struggle to deliver timely and high-quality diagnostics and care in a health system with a per capita healthcare expenditure of only €400 a year ‒ the lowest of any European country. With the coronavirus crisis now testing the resilience of even the best resourced
- [Cancer nursing, COVID-19 and healthcare inequality](https://cancerworld.net/cancer-nursing-covid-19-and-healthcare-inequality/) - This year European Cancer Nursing Day ECND2020 on 18 May will be special because this is the World Health Organisation’s Year of the Nurse and Midwife; but also because it takes place in the midst of the current COVID-19 crisis. Months ago, before the pandemic, EONS decided that the theme of ECND2020 would be the
- [EORTC pushes for the State of Science in Care](https://cancerworld.net/eortc-and-ecco-push-for-the-state-of-science-in-care/) - Covid-19 has taught us that we need to think differently about many issues. One of the most important, in my view, is that we need to be ready to act quickly and decisively rather than just identifying and talking about potential problems. In the oncology field, we have been discussing the importance of the role
- [COVID-19 is delaying diagnosis, but getting back to normal is not what we need](https://cancerworld.net/covid-19-is-delaying-diagnosis-but-getting-back-to-normal-is-not-what-we-need/) - Zorana Maravic is head of operations at Digestive Cancers Europe Across the globe, all human and technical resources in healthcare are currently focused on dealing with the COVID-19 pandemic, which is having an impact on other areas of healthcare. At Digestive Cancers Europe, the patient advocacy group for people with colorectal, gastric, pancreatic, liver and
- [Workload doubled, resources halved: cancer patient groups need help to survive the pandemic](https://cancerworld.net/workload-doubled-resources-halved-cancer-patient-groups-need-help-to-survive-the-pandemic/) - COVID-19 is creating significant challenges for millions of cancer patients around the world, including delays in diagnosis and treatment ‒ all made worse by an underlying concern about the essential safety of cancer patients during a pandemic. Since the outset of this pandemic, patient advocacy organisations have stepped up their activities to ensure that cancer
- [Night-shift work and breast cancer risk: potential biological mechanism identified](https://cancerworld.net/night-shift-work-and-breast-cancer-risk-potential-biological-mechanism-identified/) - Is night-shift work a risk factor for breast cancer? Experimental research just published in Nature Communications gives the molecular basis for asserting that it may well be. Researchers at Paris-Saclay University, with colleagues from Inserm and Inrae, studied the association between night work and increased tumour aggressiveness. They created a simulated jet-lag situation for mice
- [Cervical cancer: the SENTIX trial](https://cancerworld.net/cervical-cancer-the-sentix-trial/) - Interview with David Cibula, MD, Department of Obstetrics and Gynaecology, First Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic. Q. Your recent paper in the European Journal of Cancer (EJC 137 (2020) 69-80) on the SENTIX trial is clearly the result of a considerable effort at international level, with many contributing
- [Dose dense chemotherapy in Luminal B breast cancers](https://cancerworld.net/dose-dense-chemotherapy-in-luminal-b-breast-cancers/) - Interview with Lucia Del Mastro, MD, Department of Internal Medicine and Medical Specialties, School of Medicine, University of Genova, Italy. Q. Your recent paper in the European Journal of Cancer (EJC 136 (2020) 43-51) on the GIM2 trial is clearly the result of a considerable effort at national level, with many contributing centres all over
- [NHS England’s pilot of cancer screening blood test raises questions](https://cancerworld.net/nhs-englands-pilot-of-cancer-screening-blood-test-raises-questions/) - The UK National Health Service (NHS) announced on the 27 November that it would be piloting an early detection multi-cancer blood test next year. This represents an important advance because “every year, nearly 200,000 people in the UK die from cancer. Many of these people are diagnosed too late for treatment to be effective,” said
- [Croatia’s cancer plan showcases the value of European cancer collaboration](https://cancerworld.net/croatias-cancer-plan-showcases-the-value-of-european-cancer-collaboration/) - Croatia has caught up with the rest of the EU in adopting a national cancer control plan. Sophie Fessl looks at how using EU guidance drawn from experiences of other member states helped them ensure it is relevant, patient-centred, and capable of implementation. Croatia's cancer survival rates are among the worst in Europe for many
- [In memory of Aron Goldhirsch, challenging oncologist with a vision](https://cancerworld.net/in-memory-of-aron-goldhirsch-chanllenging-oncologist-with-a-vision/) - Prof. Aron Goldhirsch, an outstanding representative of italian Medical Oncology, awarded and recognized internationally, passed away on February 26. Since 2019, he was Medical Consultant at the Breast Cancer Center in Multimedica (Milan, Italy). For many years he held the position of Senior Consultant for the Senology Program and Director of the Melanoma, Sarcoma and
- [Dino Amadori passes away at the age of 83](https://cancerworld.net/dino-amadori-passes-away-at-the-age-of-83/) - Soul and courage: these are the two words italian oncologist Dino Amadori chose in the autobiography he published less than two years ago to describe what guided him alla along his “life against cancer”. Dino Amadori, among the fathers of Italian oncology, passed away at the end of February, at the age of 83. He
- [Lynn Faulds Wood: consumer rights watchdog who took up the cause of cancer patients](https://cancerworld.net/lynn-faulds-wood-consumer-rights-watchdog-who-took-up-the-cause-of-cancer-patients/) - Many tributes have been paid to Lynn Faulds Wood, the co-founder and first president of the European Cancer Patient Coalition (ECPC), who has died aged 72. She had a profound influence on giving voice to European cancer patients and advocates at a time when they lacked power in pressing for better care and treatment.Speaking truth
- [Solange Peters: ESMO President](https://cancerworld.net/president-of-the-european-society-for-medical-oncology/) - The second woman ever to hold the ESMO presidency, Solange Peters brings to the role impressive clinical and research experience in lung cancer, one of the most challenging and fast-moving areas of oncology. Cancer World asked her about how ESMO is adapting to meet the needs of oncologists in today’s complex and rapidly changing clinical
- [Karen Benn: a great example of what an advocate can accomplish](https://cancerworld.net/karen-benn-a-great-example-of-what-an-advocate-can-accomplish/) - Tributes have poured in for Karen Benn, deputy CEO and head of public affairs at Europa Donna, who died on 4 September. Karen was one of the longest serving officers at Europa Donna, the European Breast Cancer Coalition that unites advocacy in Europe, having joined in 2003 after working in the business sector for a
- [Stella Kyriakides: EU Commissioner for Health](https://cancerworld.net/stella-kyriakides-eu-commissioner-for-health/) - When Stella Kyriakides took on the post of EU Health Commissioner in September 2019, Europe’s cancer community knew they could trust her to fight their cause. Within months she was launching a public consultation on Europe’s Beating Cancer Plan. Then came COVID. Alberto Costa asked her how her experience as a breast cancer survivor and
- [Tackling cancer in interesting times](https://cancerworld.net/tackling-cancer-in-interesting-times/) - Being Venetian by birth, I am a keen visitor to the Biennale – the contemporary art exhibition that is hosted by the city every two years. In 2019, reflecting this period of tumultuous change, the Biennale adopted the theme: “May You Live in Interesting Times”. The phrase could be interpreted as a wish or a
- [These COVID days](https://cancerworld.net/these-covid-days/) - ‘Tackling cancer in interesting times’ was the theme of my first Editorial for Cancer World. I wrote that at the start of February this year, at a time when Europe remained largely oblivious to the implications of a new virus that had been wreaking havoc in parts of China. Within weeks, the spread of the
- [Adriana Albini, editor in chief, presents Cancer World issue 89](https://cancerworld.net/adriana-albini-editor-in-chief-presents-cancer-world-issue-89/) - Editor Adriana Albini talks readers through the stories we’ve selected for our Winter print issue. They cover a wide range of topics, but are really interested only in one thing: how do we improve the quality of care we tailor to every patient? Take a look (5 mins) https://youtu.be/ig4RdfDztu4 Click here to download CW issue
- [Building back cancer services after Covid-19: European Cancer Organisation plan](https://cancerworld.net/building-back-cancer-services-after-covid-19-european-cancer-organisation-plan/) - The European Cancer Organisation has proposed seven urgent recommendations to ‘build back cancer services better’ after the ongoing challenges resulting from the Covid-19 pandemic. ‘The Impact of COVID-19 on Cancer in Europe’, launched during the European Cancer Summit on the 18th November, aims to rectify the devastating impact that the virus has had on cancer
- [A 360° approach to a 360° problem: why a mission is the right approach to solving cancer](https://cancerworld.net/a-360-approach-to-a-360-problem-why-a-mission-is-the-right-approach-to-solving-cancer/) - Medical researcher Bettina Ryll learned about the gap between how research is done and what patients need when her husband was diagnosed with metastatic melanoma in 2011. She set up Melanoma Patient Network Europe and opened up discussions on how to better align the needs of patients and research (eg MPNE2015- the risk of NOT
- [Prolonged ADT use in prostate cancer increases CV mortality: A need for cardiovascular protection](https://cancerworld.net/prolonged-adt-use-in-prostate-cancer-increases-cv-mortality-a-need-for-cardiovascular-protection/) - Prolonged androgen deprivation therapy (ADT) exposure was found to be associated with reduced cardiorespiratory fitness (CRF) and increased cardiovascular (CV) mortality. The study, published in JACC: CardioOncology, emphasizes the need to consider CV surveillance and risk modification for men both during and after ADT exposure. ADT is a standard primary treatment for prostate cancer with
- [Serious patient-reported outcomes data gap in immunotherapy trials revealed](https://cancerworld.net/serious-patient-reported-outcomes-data-gap-in-immunotherapy-trials-revealed/) - A review of trials of immunotherapy agents revealed a ‘considerable gap’ in the use of patient reported outcomes (PROs), reports a recent study. The data analysis study found PROs were included in less than half of the 44 immunotherapy trials analysed, identifying the need for increased efforts to maximize the clinical utility of such data
- [Machine learning mortality predictions boost end-of-life conversations](https://cancerworld.net/machine-learning-mortality-predictions-boost-end-of-life-conversations/) - A study of the use of machine learning to predict the risk of dying within six months, combined with behavioural nudges, led to increased serious illness conversations between oncologists and cancer patients. “To our knowledge, this is one of the first randomized clinical trials testing the effect of real-time machine learning predictions and behavioural nudges
- [Roundtable ‘grasps nettle’ on European cancer inequalities](https://cancerworld.net/roundtable-grasps-nettle-on-european-cancer-inequalities/) - Improving treatment of older patients and closing the East−West divide were the focus of a Community 365 Roundtable on Inequalities organised by the European Cancer Organisation on the 14th October. This event was the first of a series of Community 365 roundtable meetings. Community 365 is an European Cancer Organisation initiative that brings together charity,
- [In memoriam: Alfredo Die Goyanes, oncology surgeon](https://cancerworld.net/in-memoriam-alfredo-die-goyanes-oncology-surgeon/) - It is not possible! Alfredo has passed away, he has not been able to overcome the attack of the damn virus that devastates lives and feelings. I try to control my memories, my friendship with him and the enormous gratitude for everything he did and I will try to reflect the example of his life
- [Four steps to eliminating HPV-related cancers: a call for action](https://cancerworld.net/four-steps-to-eliminating-hpv-infections-across-europe-an-ecco-call-for-eu-action/) - A new report underlines that vaccination, screening, treatment and public awareness, provide the cornerstone for eliminating cancers linked to the human papillomavirus (HPV) in Europe. The report was published by The European Cancer Organisation, Brussels on 7th October. The report, ‘Viral Protection: Achieving the Possible’ details a four step plan that calls for urgent action
- [Cancer deaths fall, health disparities persist, cancer research affected, reports AACR](https://cancerworld.net/cancer-deaths-fall-health-disparities-persist-cancer-research-hit-reports-aacr/) - The American Association for Cancer Research (AACR) annual Cancer Progress Report for 2020, published 23 September, portrays a mixed picture. On a positive note, the report features advances in cancer treatment and falls in cancer-related deaths; while on the negative side, it shows certain segments of the population shoulder a disproportionate burden of cancer and
- [Metastatic prostate cancer: cabazitaxel shows quality of life benefits over both abiraterone and enzalutamide](https://cancerworld.net/metastatic-prostate-cancer-cabazitaxel-shows-quality-of-life-benefits-over-both-abiraterone-and-enzalutamide/) - In addition to previously reported survival benefits, the taxane cabazitaxel improved quality of life in patients with advanced metastatic prostate cancer compared to the androgen signalling targeted inhibitors abiraterone and enzalutamide, reports the latest analysis of the CARD trial (Fizazi K et al. Lancet Oncol 2020). “This analysis can provide reassurance to physicians and patients
- [Combined therapies offer the key to drug-resistant cancer](https://cancerworld.net/combined-therapies-offer-the-key-to-drug-resistant-cancer/) - For the first time, an investigator initiated phase 1b study tested the combination of the PARP inhibitor olaparib, and the AKT inhibitor capivasertib, and showed this combination was well tolerated and achieved durable responses in patients with treatment-refractory breast, ovarian and prostate cancers. The results were published in the journal Cancer Discovery (Yap TA et
- [New European Code of Cancer Practice defines patient rights along the cancer pathway](https://cancerworld.net/new-european-code-of-cancer-practice-defines-patient-rights-along-the-cancer-pathway/) - The European Code of Cancer Practice was launched on 23rd September in Brussels by the European Cancer Organisation to empower citizens with 10 key ‘overarching’ rights and reduce cancer care inequalities across Europe. “This powerful new tool sets out the core requirements for excellence in clinical cancer practice to improve outcomes for all cancer patients
- [Preclinical model identifies predictors of checkpoint inhibitor response](https://cancerworld.net/preclinical-model-identifies-predictors-of-checkpoint-inhibitor-response/) - A study published in PNAS (Chen IX, et al. PNAS 2020) of a new mouse model has enabled the identification of distinct gene signatures that distinguish responders from non-responders to immune checkpoint blockade (ICB). “Our findings provide a general approach for investigating mechanisms of resistance to ICB and identifying predictive biomarkers of response,” write the
- [New transatlantic partnership to regain the momentum of cancer research](https://cancerworld.net/new-transatlantic-partnership-to-regain-the-momentum-of-cancer-research/) - Building on the existing Cancer Research UK (CRUK) Grand Challenges initiative, a broader international collaboration has now been forged in partnership with the National Cancer Institute (NCI) in the US. This new Cancer Grand Challenges has been launched to seek novel ideas to address the most profound unanswered research questions in cancer. The partnership, between
- [ESMO provides first recommendations on use of next-generation sequencing in metastatic cancer](https://cancerworld.net/esmo-provides-first-recommendations-on-use-of-next-generation-sequencing-in-metastatic-cancer/) - Patients with metastatic non-squamous non-small-cell lung cancer (NSCLC), prostate cancers, ovarian cancers and cholangiocarcinoma should be offered next-generation sequencing (NGS) for profiling tumour samples, concludes an expert panel from the European Society for Medical Oncology (ESMO) in their review (Mosele F et al. Ann Oncol 2020) published in Annals of Oncology (August 24). “These are
- [COVID-19 diagnostic delays predicted to increase cancer deaths](https://cancerworld.net/covid-19-diagnostic-delays-predicted-to-increase-cancer-deaths/) - Substantial increases in the number of avoidable cancer deaths in England are predicted as a result of diagnostic delays due to the COVID-19 pandemic, report two modeling studies published in the August issue of Lancet Oncology. Both studies underline the urgent need in the time of COVID-19 for public education programmes to be introduced across
- [Dietary counseling remains cornerstone of cachexia management, say new ASCO guidelines](https://cancerworld.net/dietary-counseling-remains-cornerstone-of-cachexia-management-say-new-asco-guidelines/) - For cancer cachexia, dietary counseling should be offered with the goal of providing patients and caregivers with management advice, conclude the first guidelines on cachexia ever published by the American Society of Clinical Oncology (ASCO). In the absence of evidence, the new guidelines, published in the Journal of Clinical Oncology, add that no specific pharmacological
- [20-year WHI follow-up study finds oestrogen selectively protects against breast cancer in women who have undergone hysterectomy](https://cancerworld.net/20-year-whi-follow-up-study-finds-oestrogen-selectively-protects-against-breast-cancer-in-women-who-have-undergone-hysterectomy/) - A 20-year follow-up of the two Women’s Health Initiative (WHI) hormone replacement studies found that, among postmenopausal women with prior hysterectomy, use of oestrogen in comparison to placebo was associated with lower breast cancer incidence and mortality, while among those with intact uteruses, use of oestrogen plus progesterone was associated with higher breast cancer incidence,
- [Dietary guidelines need reform to meet global health and environmental goals](https://cancerworld.net/dietary-guidelines-need-reform-to-meet-global-health-and-environmental-goals/) - National dietary guidelines in most countries need to be reformed to take into account health and environmental targets, concludes a study published in the BMJ (published online July 15). The international study, by UK, US and Australian investigators, found around one-third of national food based dietary guidelines (FBDGs) to be incompatible with the non-communicable diseases
- [Link between COVID-19 and prostate cancer raises possibility of new treatments](https://cancerworld.net/link-between-covid-19-and-prostate-cancer-raises-possibility-of-new-treatments/) - The overlapping biology identified between the molecular pathogenesis of COVID-19 and prostate cancer raises the possibility of repurposing drugs, including androgen deprivation therapy, for treating COVID-19, suggests a review in Nature Communications Biology, published 8 July. In the review the US authors additionally highlight the increased vulnerability of prostate cancer patients to COVID-19 and call
- [The burden of thyroid cancer increases worldwide](https://cancerworld.net/the-burden-of-thyroid-cancer-increases-worldwide/) - The global burden of thyroid cancer is increasing worldwide, according to a cross-sectional study with data from 195 countries just published in Jama Network Open. The study, by Jun Lyu and colleagues from the Jinan University in Guangzhou, China, evaluated the burden and variation trends of thyroid cancer between 1990 and 2017 at the global,
- [AACR: cancer vaccine combination shows clinical activity in advanced solid tumors](https://cancerworld.net/aacr-cancer-vaccine-combination-shows-clinical-activity-in-advanced-solid-tumors/) - According to an industry-funded, preliminary clinical trial presented at the AACR Virtual Annual Meeting currently underway, a personalized cancer vaccine in combination with the PD-L1 inhibitor atezolizumab appears to be well tolerated and to show modest clinical benefit in patients with advanced solid malignancies. “Many cancers are able to successfully avoid the immune system, and
- [Cancer prevention through physical activity and diet: an updated guideline from the U.S.](https://cancerworld.net/cancer-prevention-through-physical-activity-and-diet-an-updated-guideline-from-the-u-s/) - According to the latest update of the American Cancer Society (ACS) guideline, four main pillars are needed to keep cancer away using diet and exercise. Here they are: achieve and maintain a healthy body weight throughout life, be physically active, follow a healthy eating pattern at all ages, and it is best not to drink
- [The burnout epidemic in oncology, highlights form ASCO 2020](https://cancerworld.net/the-burnout-epidemic-in-oncology-highlights-form-asco-2020/) - “Burnout is universal and no one is immune. We are all in this together and together we can come up with solutions”. Tara Sanft, Associate Professor of Medicine at the Yale School of Medicine, New Haven (U.S.A.), came to these conclusions in a poster discussion during the (virtual) annual meeting of the American Society of
- [Cancer drugs, costs and clinical benefits are not aligned](https://cancerworld.net/cancer-drugs-costs-and-clinical-benefits-are-not-aligned/) - According to an international study just published in Lancet Oncology, the cost of new cancer drugs is not associated to the clinical value of the therapy: “In the USA and European countries, prices of cancer drugs should be better aligned with their clinical importance, such as by prioritising drugs with low or uncertain benefit for
- [A global registry for children with cancer and COVID-19](https://cancerworld.net/a-global-registry-for-children-with-cancer-and-covid-19/) - While a deeper knowledge about the impact of COVID-19 disease on cancer patients is essential, sharing information is likewise important. For these purposes, a number of registries, which gather different data including patients’ outcomes or treatment, are being set up around the world. The first global COVID-19 registry dedicated to children with cancer was launched recently
- [Hormone therapy for prostate cancer may shield from COVID-19](https://cancerworld.net/hormone-therapy-for-prostate-cancer-may-shield-from-covid-19/) - Prostate cancer patients treated with androgen-deprivation therapies (ADTs) seem to have a lower risk of SARS-CoV-2 infection and COVID-19 complications compared to patients not treated with ADTs and compared to other cancer patients. If confirmed, a short term treatment with ADT may be considered in male individuals at high risk of severe COVID-19. The protective
- [The misuse of “noninferiority” in presenting trials is often misleading](https://cancerworld.net/the-misuse-of-noninferiority-in-presenting-trials-is-often-misleading/) - When researchers have the opportunity to present their trials at medical meetings, they tend to use not-negative conclusions to discuss formally negative results. A research published in JAMA Oncology by a group of Italian oncologists from the University of Turin and the National Cancer Institute - "Fondazione G. Pascale", Naples, shows that one third of
- [Artificial intelligence might help improve the classification of colorectal polyps](https://cancerworld.net/artificial-intelligence-might-help-improve-the-classification-of-colorectal-polyps/) - Deep neural networks are as good as practicing pathologists in classifying colorectal polyps, according to an experiment by a computer science and clinical research team led by Saeed Hassanpour, from the Dartmouth Cancer Center in Lebanon (New Hampshire). The team trained one such model on data from a single-center, and then checked its abilities in
- [Gender equality in cancer research is still far away](https://cancerworld.net/gender-equality-in-cancer-research-is-still-far-away/) - Despite a positive trend toward equality in the past 3 decades, a substantial gendered difference is now persisting in oncology publications, favouring male first and last authors. “The academic medicine pipeline poses a significant challenge for workforce development, with disproportionately low female representation in high-ranking positions” wrote the authors – all women – of a
- [European heavy weights share their wisdom on how to deal with COVID-19 and cancer](https://cancerworld.net/european-heavy-weights-share-their-wisdom-on-how-to-deal-with-covid-19-and-cancer/) - The consortium Cancer Core Europe has collected, elaborated and shared the steps top experts have taken, while scientific evidence is still in the making Several top cancer centres from all around Europe have just published the results of their in-depth analysis of the challenges posed by the COVID-19 pandemic, that imposes a new way of
- [The prevalence of vaping among cancer survivors is worrying](https://cancerworld.net/the-prevalence-of-vaping-among-cancer-survivors-is-worrying/) - The use of electronic cigarettes, or vaping, seems to be particularly common among young cancer survivors: according to a survey on a sample of nearly 1,500 young adult (YA) cancer survivors, just published as a research letter in JAMA Oncology, almost half have ever used e-cigarettes and more than one quarter are current users. Notably,
- [What we know, and ignore, of pediatric palliative care](https://cancerworld.net/what-we-know-and-ignore-of-pediatric-palliative-care/) - In discussing palliative care, it has often been asked whether quality of time was important like quantity of life, if not more. And, when patients are children, the answer can become very complex. «If the goal of palliative care is not simply to choose quantity vs quality but instead to help patients live their best
- [Trends in liver cancer: is it time to change prevention strategies?](https://cancerworld.net/trends-in-liver-cancer-is-it-time-to-change-prevention-strategies/) - Between 1990 and 2017 the incidence of primary liver cancer (PLC) globally decreased in younger (<30 years) and middle-aged (30-50 years), while increasing in older people (>60 years). Primary prevention strategies and changes in the lifestyle could be mentioned as determinants of these trends, according to the results of a paper recently published in Cancer
- [COVID-19: Cancer World editor and immunologist Adriana Albini explains how it works and how researchers are hoping to tame it](https://cancerworld.net/covid-19-cancer-world-editor-and-immunologist-adriana-albini-explains-how-it-works-and-how-researchers-are-hoping-to-tame-it/) - International collaboration, data sharing and investing in research is how we’ll tame the COVID-19 virus, explains Cancer World editor Adriana Albini. An immunologist now on the Board of Directors of the American Association of Cancer Research, Albini was part of the huge and successful international research effort to tame the HIV epidemic in the 1990s.
- [AACR calls on US Congress to take quick action against COVID-19](https://cancerworld.net/aacr-calls-on-us-congress-to-take-quick-action-against-covid-19/) - The Board of Directors of the American Association for Cancer Research (AACR) wrote to the members of the US Congress urging them to act quickly to overcome the COVID-19 pandemic: «Time is of the essence, and we call on you and your colleagues in Congress to move swiftly forward to take the following steps to
- [Parity and breast cancer risk are not so strictly linked](https://cancerworld.net/parity-and-breast-cancer-risk-are-not-so-strictly-linked/) - The reduction in birth rate has been blamed in the past for the increase in breast cancer in young women, but now a study just published in JAMA Network Open (JAMA Netw Open. 2020;3(3):e200929. doi:10.1001/jamanetworkopen.2020.0929) offers evidence refuting this hypothesis: analysing data going back to the 1930s, a group led by Mary Beth Terry, professor
- [Cancer survivors need more (and longer) support](https://cancerworld.net/cancer-survivors-need-more-and-longer-support/) - After defeating cancer, people are facing other worries, which too often remain unsolved, even though they are seeking for help, according to a Canadian study concluding that it’s time to enhance survivorship care: «Without appropriate support systems in place, these cancer survivors face a substantial burden because of the inadequacy of health care services in
- [COVID-19: ECCO demands attention to protect cancer patients](https://cancerworld.net/covid-19-ecco-demands-attention-to-protect-cancer-patients/) - The COVID-19 pandemic poses a significant threat for cancer patients, which deserve to be protected through immediate action on several levels all over Europe, according to a statement published today by the European Cancer Organisation (ECCO). Matti Aapro, President of the European Cancer Organisation, referred specifically to the shortage of materials that are key to
- [Can we still rely on Omega-3 & Co. for cancer prevention and management?](https://cancerworld.net/can-we-still-rely-on-omega-3-co-for-cancer-prevention-and-management/) - According to an extensive systematic review recently published in the British Journal of Cancer, there is no evidence for a protective role of polyunsaturated fat (PUFAs) against the risk of cancer. Moreover, a very high intake of total PUFAs could slightly increase cancer risk, although the quality of evidence is low. “Evidence for effects of
- [COVID-19 and cancer, still more questions than answers](https://cancerworld.net/covid-19-and-cancer-still-more-questions-than-answers/) - COVID-19 outbreak poses a severe threat to the health of millions of people worldwide, including cancer patients. What do we know about SARS-CoV-2 infection in this specific population? The analysis of data coming from a prospective cohort established by the National Clinical Research Centre for Respiratory Disease together with the National Health Commission of the
- [More evidence-based info on off-patent oncology drugs](https://cancerworld.net/more-evidence-based-info-on-off-patent-oncology-drugs/) - The American Association for Cancer Research (AACR) has offered help to the U.S. Food and Drug Administration (FDA) on its ambitious Project Renewal, that aims to evaluate accumulated scientific evidence on safety and efficacy of long-standing off-patent oncology drugs, so to update labeling information. Over time, drug labeling becomes outdated as new information becomes available
- [A step forward in prostate cancer screening optimisation](https://cancerworld.net/a-step-forward-in-prostate-cancer-screening-optimisation/) - A single prostate-specific antigen (PSA) measurement in midlife may help to personalise prostate cancer screening, resulting in a reduced risk of overdiagnosis and overtreatment of indolent cancers. The authors of the study just published in JAMA Network Open came to this conclusion after finding that in a cohort of nearly 11,000 man aged 55 to 60
- [UNESCO pledges to end the gender imbalance in science](https://cancerworld.net/unesco-pledges-to-end-the-gender-imbalance-in-science/) - Science and gender equality are both vital for the achievement of the internationally agreed development goals, including the 2030 Agenda for Sustainable Development. Over the past 15 years, the global community has made a lot of effort in inspiring and engaging women and girls in science. Yet women and girls continue to be excluded from
- [Everyone is invited to help with the EU Beat Cancer Plan](https://cancerworld.net/everyone-is-invited-to-help-with-the-eu-beat-cancer-plan/) - Today, on World Cancer Day, the European Commission president Ursula von der Leyen announced the launch of a EU-wide public consultation on the forthcoming “Beating Cancer Plan”, which aims to improve prevention, diagnosis, treatment and care of cancers in the European Union. In her speech at the European Parliament, von der Leyen recalled how her
- [New evidence shows effectiveness of a single-dose of HPV vaccine](https://cancerworld.net/new-evidence-shows-effectiveness-of-a-single-dose-of-hpv-vaccine/) - To prevent pre-invasive cervical disease, a single dose of the human papillomavirus (HPV) vaccine could be enough. Investigation of more than 130,000 young women suggests that 1 dose of quadrivalent (4vHPV) vaccine has the same effectiveness of 2 doses, recommended for all adolescents before the age of 15, or more. «Overall, our findings showed a
- [Non-cancer drugs repurposing, a new trick to win the onco-challenge?](https://cancerworld.net/non-cancer-drugs-repurposing-a-new-trick-to-win-the-onco-challenge/) - Originally developed and approved for use in diabetes, inflammation and other non-oncological diseases (even osteoarthritis in dogs), many drugs could have a pivotal role in treating cancer. And they could be more abundant than expected, according to a paper recently published in Nature Cancer. “Anticancer uses of non-oncology drugs have occasionally been found, but such
- [Genetics of breast cancer: much more than a BRCA story](https://cancerworld.net/genetics-of-breast-cancer-much-more-than-a-brca-story/) - Over 450 departments and institutions worldwide have contributed to the most comprehensive study conducted so far on breast cancer risk variants whose results have been published in Nature Genetics. The fine mapping of 150 breast cancer risk regions identified nearly 200 likely target genes. Notably, less than one in five of these target genes had
- [The European Parliament launches a new committee on cancer](https://cancerworld.net/the-european-parliament-launches-a-new-committee-on-cancer/) - The European Parliament has announced the establishment of a Special Committee on Cancer: "If we combine our research, our resources and our experience, the European Union can beat cancer. Experts are telling us it is possible" said Manfred Weber, Chairman of the European People’s Party political group which pushed for the committee, in the context of
- [More data on physical activity and reduction of cancer risk](https://cancerworld.net/more-data-on-physical-activity-and-reduction-of-cancer-risk/) - Recommended leisure-time physical activity is associated with a lower risk of 7 types of cancer, according to a new study published on Journal of Clinical Oncology. «In the past decade, our knowledge of the number of cancers linked to physical activity has expanded substantially, but whether engagement in recommended amounts of leisure-time physical activity may
- [Real-world evidence in oncology has benefits (and risks)](https://cancerworld.net/real-world-evidence-in-oncology-has-benefits-and-risks/) - Despite some weaknesses, real-world data can have a pivotal role in oncology, helping researchers and physicians to better understand the efficacy of anti-cancer treatments and how to manage the side effects. This is the position expressed in a commentary published in The Oncologists by three Italian experts: Massimo Di Maio from University of Turin, Francesco
- [Artificial intelligence is prone to overdiagnosis](https://cancerworld.net/artificial-intelligence-is-prone-to-overdiagnosis/) - The use of artificial intelligence might increase the speed and the consistency of cancer diagnosis, but could also exacerbate the problem of overdiagnosis, according to a perspective article recently published in the New England Journal of Medicine by Adewole Adamson and Gilbert Welch, who suggest that this risk may be mitigated by overcoming the dichotomous classification

## Pages

- [Home CW](https://cancerworld.net/) - CancerWorld delivers expert insights on oncology, innovation, prevention, and patient care, bringing together global leaders, science, and stories shaping the future of cancer.
- [Editorial Team](https://cancerworld.net/editorial-team/) - Co-Editors-in-Chief: Adriana Albini Managing Editor: Knarik Arakelyan News Editor: Janet Fricker Editorial Board: Ajay Aggarwal (UK), Professor of Cancer Services and Systems Research, King’s College London and London School of Hygiene and Tropical Medicine (LSHTM); Consultant Clinical Oncologist, Guy’s and St Thomas’ NHS Trust, Co-chair of the Health Economics in Radiation Oncology (HERO) Group, European Society
- [Journal staff](https://cancerworld.net/about-the-magazine/journal-staff/) - Co-Editors-in-Chief: Prof. Adriana Albini Managing Editor: Knarik Arakelyan Website: yStudium (www.ystudium.com)
- [About us](https://cancerworld.net/about-the-magazine/) - Founded in 2004, Cancerworld is an independent magazine for oncologists and other cancer professionals, policy makers and patient advocates. Written largely by professional journalists, it invites people from all walks of the cancer community to contribute their expertise and experience to exploring issues that impact on outcomes that matter to patients. From 2020 to 2024
- [ESO College Corner](https://cancerworld.net/esco-corner/) - The College of the European School of Oncology (ESO College), together with Cancerworld magazine, is giving members and faculty of the ESO College the chance to voice their views and perspectives on certain topics related to oncology via its writing contest. We are looking for clear and concise views from oncology professionals on topics facing them
- [Magazine](https://cancerworld.net/magazine/)
- [Events](https://cancerworld.net/events/) - Cancerworld supports scientific initiatives in the field of cancer education, care improvement and innovation.
- [Contacts](https://cancerworld.net/contacts/) - For comments or suggestions fill the form Your Name * Your Email * Subject * Your Message * I declare that I have read the privacy policy
- [Cancer Journalist Grant](https://cancerworld.net/media-corner/cancer-journalist-grant/) - European School of Oncology's Cancer Journalist Grant encourages high-quality reporting on cancer. The Grant enables print, broadcast and new media journalists to complete a reporting project on a particular topic relating to cancer. We look for projects that explore systemic issues that have a significant impact on cancer patients and that provide comprehensive coverage on
- [Cancer Journalism Award](https://cancerworld.net/media-corner/cancer-journalism-award/) - The Cancer Journalism Award is an annual award that recognises and encourages excellent cancer journalism. The Award encourages, celebrates and rewards journalists who deliver insights into the personal and social effects of the disease, and the impact of policy, practice and advocacy. Is your journalism improving public understanding of cancer? The Cancer Journalism Award is
- [Media Corner](https://cancerworld.net/media-corner/) - The European School of Oncology in collaboration with Cancerworld magazine organises several initiatives for journalists who report on cancer with the overall aim of recognizing and promoting high-quality cancer journalism and to help change the way we think about cancer. Journalist Cancer Guide Cancer Journalism Award Cancer Journalism Grant
- [Journalist Cancer Guide](https://cancerworld.net/media-corner/journalist-cancer-guide/) - ESO organises several initiatives for and with the International media. Here is a list of the most recent and relevant ones. Making Sense of Cancer - a journalist's guide Covering cancer stories is a rich and rewarding area of journalism – but it is also difficult. Drawing on years of experience writing for Cancer World,

## Awards

- [Cancer Journalism Award winners 2021](https://cancerworld.net/cj_award/cancer-journalism-award-winners-2021/) - Outstanding journalism recognised in ESO Award Journalists from Italy, Germany and the UK have been recognised for their outstanding achievement in the 2021 Cancer Journalism Award, organised by the European School for Oncology (ESO) in Milan, Italy. There were winners in three categories, who each receive €1500, with the overall winner receiving an additional €500.
- [Cancer Journalism Award winners 2019-2020](https://cancerworld.net/cj_award/2019-2020/) - Outstanding reporting recognised in ESO’s Cancer Journalism Award Journalists from Germany, Belgium, Kenya and Mexico have been recognised for their outstanding achievement in the 2019-20 Cancer Journalism Award, organised by the European School for Oncology (ESO) in Milan, Italy.The overall winner was Anne Preger from Germany, whose podcast “Chance in Phase 2” explored a range
- [Best Cancer Reporter Award winners (2006 – 2015)](https://cancerworld.net/cj_award/2015/) - 2015 Best Cancer Reporter Award 1st Prize: Matthew Hill, BBC, UK2nd Prize: Patrice Goldberg, Matière Grise, Belgium 2014 Best Cancer Reporter Award 1st Prize: Steven Buist, Hamilton Spectator, CanadaJoint 2nd Prize:Katrin Zoefel, Deutschlandfunk, Germany,Jason Gale, Bloomberg Markets, Australia In addition, American journalist Clifton Leaf received a Best Cancer Reporter Lifetime Achievement award for his outstanding contribution to cancer journalism.
- [2016 Cancer World Journalism Award winners](https://cancerworld.net/cj_award/2016/) - Overall winner Pia Heinemann from Germany won the Research, Science and Treatment category for her article published in Welt Am Sonntag about the need for gene testing to prevent many cancer patients from having unnecessary chemotherapy. The judges were impressed that she had written about a complex and important subject in such an accessible manner. They decided
- [2018 Cancer World Journalism Award winners](https://cancerworld.net/cj_award/2018/) - Overall winner Swagata Yadavar from India won the Policy, Services and Affordability category for her investigation into India’s growing cancer crisis, centred around experiences at the Tata Memorial Hospital in Mumbai. It was published in IndiaSpend, the country’s first not-for-profit data journalism initiative. Patient and Carer Experience category winner The winner in the Patient and Carer Experience

## Grants

- [2022](https://cancerworld.net/grant/2022/) - In 2022, Taras Zozulinskyy a Ukrainian journalist from the Bureau of Journalistic Investigations "Detectives" was awarded a special Cancer Journalist Grant to help him create a series of videos to describe and show the situation in which cancer patients in Ukraine found themselves since the Russian invasion. The videos are available below and translated into
- [2014](https://cancerworld.net/grant/2014/) - In 2014 a grant was awarded to two European freelance journalists: Maria Delaney from Ireland for her story proposal on Systematic BRCA Screening and to Prune Antoine from France for her proposal to write an article on the long-terms effects on having been treated for and survived paediatric cancer.Maria Delaney’s article, Who should we screen
- [2015](https://cancerworld.net/grant/2015/) - The 2015 Cancer World Journalist Grant was assigned to Sophie Fessl from Austria for her story proposal on the problem of drug development in paediatric oncology, where survival rates have stalled over the past 10 years. You can view Sophie’s final article here.
- [2020](https://cancerworld.net/grant/2020/) - The following journalists have been award a Cancer Journalist Grant this year and are currently working on their reports:Patrick Njoroge (Kenya) – Esophageal cancer in KenyaAstrid Viciano (Germany) – Drug prices in the EUTaras Zozulinskyy (Ukraine) – Cancer in Ukraine – conditions, treatment, corruption

## Categories

- [Senza categoria](https://cancerworld.net/category/senza-categoria/)
- [News](https://cancerworld.net/category/news/)
- [Editorials](https://cancerworld.net/category/editorials/)
- [Patient’s Voices](https://cancerworld.net/category/patients-voices/)
- [Obituaries](https://cancerworld.net/category/obituaries/)
- [Profiles](https://cancerworld.net/category/profiles/)
- [In the Hot Seat](https://cancerworld.net/category/hot-seat/)
- [Interviews to the Expert](https://cancerworld.net/category/interviews-to-the-expert/)
- [Voices](https://cancerworld.net/category/voices/)
- [Articles](https://cancerworld.net/category/articles/)
- [Policy](https://cancerworld.net/category/articles/policy/)
- [Practice Points](https://cancerworld.net/category/articles/practice-points/)
- [Delivery of Care](https://cancerworld.net/category/articles/delivery-of-care/)
- [Biology basic](https://cancerworld.net/category/articles/biology-basic/)
- [Medicine](https://cancerworld.net/category/articles/medicine/)
- [Featured](https://cancerworld.net/category/articles/featured-articles/)
- [ESO Contest](https://cancerworld.net/category/esco-contest/)
- [Science](https://cancerworld.net/category/science/)

## Tags

- [breast cancer](https://cancerworld.net/tag/breast-cancer/)
- [screening](https://cancerworld.net/tag/screening/)
- [guidelines](https://cancerworld.net/tag/guidelines/)
- [cancer](https://cancerworld.net/tag/cancer/)
- [pediatric cancer](https://cancerworld.net/tag/pediatric-cancer/)
- [research](https://cancerworld.net/tag/research/)
- [CAR-T](https://cancerworld.net/tag/car-t/)
- [CAR-T cell therapy](https://cancerworld.net/tag/car-t-cell-therapy/)
- [side effects](https://cancerworld.net/tag/side-effects/)
- [toxicity](https://cancerworld.net/tag/toxicity/)
- [Colorectal cancer](https://cancerworld.net/tag/colorectal-cancer/)
- [EGFR inhibitors](https://cancerworld.net/tag/egfr-inhibitors/)
- [Lung cancer](https://cancerworld.net/tag/lung-cancer/)
- [resistance](https://cancerworld.net/tag/resistance/)
- [EORTC](https://cancerworld.net/tag/eortc/)
- [pain](https://cancerworld.net/tag/pain/)
- [patient reported outcomes](https://cancerworld.net/tag/patient-reported-outcomes/)
- [quality of life](https://cancerworld.net/tag/quality-of-life/)
- [Artificial intelligence](https://cancerworld.net/tag/artificial-intelligence/)
- [diagnosis](https://cancerworld.net/tag/diagnosis/)
- [machine learning](https://cancerworld.net/tag/machine-learning/)
- [overdiagnosis](https://cancerworld.net/tag/overdiagnosis/)
- [cancer registries](https://cancerworld.net/tag/cancer-registries/)
- [Francesco Perrone](https://cancerworld.net/tag/francesco-perrone/)
- [health records](https://cancerworld.net/tag/health-records/)
- [Massimo Di Maio](https://cancerworld.net/tag/massimo-di-maio/)
- [oncologist](https://cancerworld.net/tag/oncologist/)
- [Pierfranco Conte](https://cancerworld.net/tag/pierfranco-conte/)
- [randomised controlled trials](https://cancerworld.net/tag/randomised-controlled-trials/)
- [rct](https://cancerworld.net/tag/rct/)
- [real-world evidence](https://cancerworld.net/tag/real-world-evidence/)
- [RWE](https://cancerworld.net/tag/rwe/)
- [physical activity](https://cancerworld.net/tag/physical-activity/)
- [prevention](https://cancerworld.net/tag/prevention/)
- [brca](https://cancerworld.net/tag/brca/)
- [BRCA mutations](https://cancerworld.net/tag/brca-mutations/)
- [genes](https://cancerworld.net/tag/genes/)
- [genetics](https://cancerworld.net/tag/genetics/)
- [drug repurposing](https://cancerworld.net/tag/drug-repurposing/)
- [hub](https://cancerworld.net/tag/hub/)
- [repurposing](https://cancerworld.net/tag/repurposing/)
- [cancer interception](https://cancerworld.net/tag/cancer-interception/)
- [Chemoprevention](https://cancerworld.net/tag/chemoprevention/)
- [Beat Cancer Plan](https://cancerworld.net/tag/beat-cancer-plan/)
- [EU](https://cancerworld.net/tag/eu/)
- [Horizon Europe](https://cancerworld.net/tag/horizon-europe/)
- [mission on cancer](https://cancerworld.net/tag/mission-on-cancer/)
- [Stella Kyriakides](https://cancerworld.net/tag/stella-kyriakides/)
- [Ursula von der Leyen](https://cancerworld.net/tag/ursula-von-der-leyen/)
- [HPV](https://cancerworld.net/tag/hpv/)
- [HPV vaccine](https://cancerworld.net/tag/hpv-vaccine/)
- [single dose](https://cancerworld.net/tag/single-dose/)
- [vaccine](https://cancerworld.net/tag/vaccine/)
- [abiraterone](https://cancerworld.net/tag/abiraterone/)
- [commensal bacteria](https://cancerworld.net/tag/commensal-bacteria/)
- [Microbiome](https://cancerworld.net/tag/microbiome/)
- [prostate cancer](https://cancerworld.net/tag/prostate-cancer/)
- [vitamin K12](https://cancerworld.net/tag/vitamin-k12/)
- [Ageing patients](https://cancerworld.net/tag/ageing-patients/)
- [East−West divide](https://cancerworld.net/tag/east−west-divide/)
- [ECCO](https://cancerworld.net/tag/ecco/)
- [National Cancer Control Plans](https://cancerworld.net/tag/national-cancer-control-plans/)
- [policy](https://cancerworld.net/tag/policy/)
- [gender](https://cancerworld.net/tag/gender/)
- [gender equality](https://cancerworld.net/tag/gender-equality/)
- [International Day of Women and Girls in Science](https://cancerworld.net/tag/international-day-of-women-and-girls-in-science/)
- [science](https://cancerworld.net/tag/science/)
- [unesco](https://cancerworld.net/tag/unesco/)
- [womeninscience](https://cancerworld.net/tag/womeninscience/)
- [PSA](https://cancerworld.net/tag/psa/)
- [AACR](https://cancerworld.net/tag/aacr/)
- [FDA](https://cancerworld.net/tag/fda/)
- [off-patent](https://cancerworld.net/tag/off-patent/)
- [oncology drugs](https://cancerworld.net/tag/oncology-drugs/)
- [project renewal](https://cancerworld.net/tag/project-renewal/)
- [DinoAmadori](https://cancerworld.net/tag/dinoamadori/)
- [hospice](https://cancerworld.net/tag/hospice/)
- [Aron Goldhirsch](https://cancerworld.net/tag/aron-goldhirsch/)
- [coronavirus](https://cancerworld.net/tag/coronavirus/)
- [covid](https://cancerworld.net/tag/covid/)
- [sars-cov](https://cancerworld.net/tag/sars-cov/)
- [cancer drugs](https://cancerworld.net/tag/cancer-drugs/)
- [cancer research](https://cancerworld.net/tag/cancer-research/)
- [chemotherapy](https://cancerworld.net/tag/chemotherapy/)
- [clinical trials](https://cancerworld.net/tag/clinical-trials/)
- [drugs](https://cancerworld.net/tag/drugs/)
- [personalised medicine](https://cancerworld.net/tag/personalised-medicine/)
- [targeted therapies](https://cancerworld.net/tag/targeted-therapies/)
- [evidence-based medicine](https://cancerworld.net/tag/evidence-based-medicine/)
- [precision medicine](https://cancerworld.net/tag/precision-medicine/)
- [cancer careers](https://cancerworld.net/tag/cancer-careers/)
- [surgery](https://cancerworld.net/tag/surgery/)
- [cancer prevention](https://cancerworld.net/tag/cancer-prevention/)
- [poly unsaturated fats](https://cancerworld.net/tag/poly-unsaturated-fats/)
- [PUFA](https://cancerworld.net/tag/pufa/)
- [cancer patients](https://cancerworld.net/tag/cancer-patients/)
- [covid-19](https://cancerworld.net/tag/covid-19/)
- [European Cancer Organisation](https://cancerworld.net/tag/european-cancer-organisation/)
- [pandemic](https://cancerworld.net/tag/pandemic/)
- [statement](https://cancerworld.net/tag/statement/)
- [cancer survivors](https://cancerworld.net/tag/cancer-survivors/)
- [unmet needs](https://cancerworld.net/tag/unmet-needs/)
- [children](https://cancerworld.net/tag/children/)
- [motherhood](https://cancerworld.net/tag/motherhood/)
- [parity](https://cancerworld.net/tag/parity/)
- [pregnancy](https://cancerworld.net/tag/pregnancy/)
- [risk](https://cancerworld.net/tag/risk/)
- [risk factors](https://cancerworld.net/tag/risk-factors/)
- [comorbidities](https://cancerworld.net/tag/comorbidities/)
- [mechanisms](https://cancerworld.net/tag/mechanisms/)
- [appeal](https://cancerworld.net/tag/appeal/)
- [US Congress](https://cancerworld.net/tag/us-congress/)
- [cancer care](https://cancerworld.net/tag/cancer-care/)
- [curative](https://cancerworld.net/tag/curative/)
- [metastatic](https://cancerworld.net/tag/metastatic/)
- [multidisciplinary team](https://cancerworld.net/tag/multidisciplinary-team/)
- [palliative](https://cancerworld.net/tag/palliative/)
- [patients](https://cancerworld.net/tag/patients/)
- [risk-benefit](https://cancerworld.net/tag/risk-benefit/)
- [shared decision making](https://cancerworld.net/tag/shared-decision-making/)
- [burden](https://cancerworld.net/tag/burden/)
- [liver](https://cancerworld.net/tag/liver/)
- [liver cancer](https://cancerworld.net/tag/liver-cancer/)
- [end of life](https://cancerworld.net/tag/end-of-life/)
- [palliative care](https://cancerworld.net/tag/palliative-care/)
- [pediatric palliative care](https://cancerworld.net/tag/pediatric-palliative-care/)
- [electronic cigarette](https://cancerworld.net/tag/electronic-cigarette/)
- [vaping](https://cancerworld.net/tag/vaping/)
- [young adults](https://cancerworld.net/tag/young-adults/)
- [ASCO](https://cancerworld.net/tag/asco/)
- [ASTRO](https://cancerworld.net/tag/astro/)
- [EHA](https://cancerworld.net/tag/eha/)
- [ESMO](https://cancerworld.net/tag/esmo/)
- [IASLC](https://cancerworld.net/tag/iaslc/)
- [Nature Medicine](https://cancerworld.net/tag/nature-medicine/)
- [career](https://cancerworld.net/tag/career/)
- [citations](https://cancerworld.net/tag/citations/)
- [gender gap](https://cancerworld.net/tag/gender-gap/)
- [journals](https://cancerworld.net/tag/journals/)
- [publications](https://cancerworld.net/tag/publications/)
- [women](https://cancerworld.net/tag/women/)
- [colonoscopy](https://cancerworld.net/tag/colonoscopy/)
- [colorectal](https://cancerworld.net/tag/colorectal/)
- [deep neural network](https://cancerworld.net/tag/deep-neural-network/)
- [polyps](https://cancerworld.net/tag/polyps/)
- [CEE](https://cancerworld.net/tag/cee/)
- [GPs](https://cancerworld.net/tag/gps/)
- [inpatient](https://cancerworld.net/tag/inpatient/)
- [outpatient](https://cancerworld.net/tag/outpatient/)
- [Romania](https://cancerworld.net/tag/romania/)
- [noninferiority](https://cancerworld.net/tag/noninferiority/)
- [not negative](https://cancerworld.net/tag/not-negative/)
- [oral presentations](https://cancerworld.net/tag/oral-presentations/)
- [resultsù](https://cancerworld.net/tag/resultsu/)
- [androgen deprivation therapy](https://cancerworld.net/tag/androgen-deprivation-therapy/)
- [prostate](https://cancerworld.net/tag/prostate/)
- [#ECND20go4EQUALITY](https://cancerworld.net/tag/ecnd20go4equality/)
- [Andreas Charalambous](https://cancerworld.net/tag/andreas-charalambous/)
- [ECND2020](https://cancerworld.net/tag/ecnd2020/)
- [EONS](https://cancerworld.net/tag/eons/)
- [European Cancer Nursing Day](https://cancerworld.net/tag/european-cancer-nursing-day/)
- [nursing](https://cancerworld.net/tag/nursing/)
- [patient advocacy](https://cancerworld.net/tag/patient-advocacy/)
- [kids](https://cancerworld.net/tag/kids/)
- [registry](https://cancerworld.net/tag/registry/)
- [delivery of care](https://cancerworld.net/tag/delivery-of-care/)
- [clinical research](https://cancerworld.net/tag/clinical-research/)
- [Magnitude of Clinical Benefit Scale](https://cancerworld.net/tag/magnitude-of-clinical-benefit-scale/)
- [price](https://cancerworld.net/tag/price/)
- [Value framework](https://cancerworld.net/tag/value-framework/)
- [clinical data](https://cancerworld.net/tag/clinical-data/)
- [evidence](https://cancerworld.net/tag/evidence/)
- [HTA](https://cancerworld.net/tag/hta/)
- [real world data](https://cancerworld.net/tag/real-world-data/)
- [registries](https://cancerworld.net/tag/registries/)
- [value](https://cancerworld.net/tag/value/)
- [melanoma](https://cancerworld.net/tag/melanoma/)
- [skin cancer](https://cancerworld.net/tag/skin-cancer/)
- [burnout](https://cancerworld.net/tag/burnout/)
- [Anne Preger](https://cancerworld.net/tag/anne-preger/)
- [Cancerworld award](https://cancerworld.net/tag/cancerworld-award/)
- [Elijah Kanyi](https://cancerworld.net/tag/elijah-kanyi/)
- [diet](https://cancerworld.net/tag/diet/)
- [nutrition](https://cancerworld.net/tag/nutrition/)
- [biomarker](https://cancerworld.net/tag/biomarker/)
- [clinical development](https://cancerworld.net/tag/clinical-development/)
- [diagnostics](https://cancerworld.net/tag/diagnostics/)
- [gene panels](https://cancerworld.net/tag/gene-panels/)
- [genomic mutations](https://cancerworld.net/tag/genomic-mutations/)
- [tissue-agnostic](https://cancerworld.net/tag/tissue-agnostic/)
- [tumour-agnostic](https://cancerworld.net/tag/tumour-agnostic/)
- [atezolizumab](https://cancerworld.net/tag/atezolizumab/)
- [cancer vaccines](https://cancerworld.net/tag/cancer-vaccines/)
- [narrative medicine](https://cancerworld.net/tag/narrative-medicine/)
- [psychology](https://cancerworld.net/tag/psychology/)
- [Thyroid cancer](https://cancerworld.net/tag/thyroid-cancer/)
- [clinical optimisation](https://cancerworld.net/tag/clinical-optimisation/)
- [high-quality care](https://cancerworld.net/tag/high-quality-care/)
- [pragmatic trials](https://cancerworld.net/tag/pragmatic-trials/)
- [registrational trials](https://cancerworld.net/tag/registrational-trials/)
- [sustainability](https://cancerworld.net/tag/sustainability/)
- [education](https://cancerworld.net/tag/education/)
- [qualification](https://cancerworld.net/tag/qualification/)
- [training](https://cancerworld.net/tag/training/)
- [circadian rhythms](https://cancerworld.net/tag/circadian-rhythms/)
- [shift work](https://cancerworld.net/tag/shift-work/)
- [metastasis](https://cancerworld.net/tag/metastasis/)
- [microenvironment](https://cancerworld.net/tag/microenvironment/)
- [therapy](https://cancerworld.net/tag/therapy/)
- [access](https://cancerworld.net/tag/access/)
- [Cancer Mission](https://cancerworld.net/tag/cancer-mission/)
- [disparities](https://cancerworld.net/tag/disparities/)
- [Europe](https://cancerworld.net/tag/europe/)
- [health](https://cancerworld.net/tag/health/)
- [non-communicable diseases](https://cancerworld.net/tag/non-communicable-diseases/)
- [cachexia](https://cancerworld.net/tag/cachexia/)
- [ERNs](https://cancerworld.net/tag/erns/)
- [European Reference Networks](https://cancerworld.net/tag/european-reference-networks/)
- [quality of care](https://cancerworld.net/tag/quality-of-care/)
- [Rare cancers](https://cancerworld.net/tag/rare-cancers/)
- [advocacy](https://cancerworld.net/tag/advocacy/)
- [biomarkers](https://cancerworld.net/tag/biomarkers/)
- [prognosis](https://cancerworld.net/tag/prognosis/)
- [prognostics](https://cancerworld.net/tag/prognostics/)
- [tools](https://cancerworld.net/tag/tools/)
- [mortality](https://cancerworld.net/tag/mortality/)
- [histopathology](https://cancerworld.net/tag/histopathology/)
- [radiology](https://cancerworld.net/tag/radiology/)
- [technology](https://cancerworld.net/tag/technology/)
- [metastatic cancer](https://cancerworld.net/tag/metastatic-cancer/)
- [mutations](https://cancerworld.net/tag/mutations/)
- [next generation sequencing](https://cancerworld.net/tag/next-generation-sequencing/)
- [funding](https://cancerworld.net/tag/funding/)
- [ReDO](https://cancerworld.net/tag/redo/)
- [regulatory](https://cancerworld.net/tag/regulatory/)
- [treatments](https://cancerworld.net/tag/treatments/)
- [immune checkpoint blockade (ICB)](https://cancerworld.net/tag/immune-checkpoint-blockade-icb/)
- [mouse model](https://cancerworld.net/tag/mouse-model/)
- [responders](https://cancerworld.net/tag/responders/)
- [TGF-β1](https://cancerworld.net/tag/tgf-β1/)
- [Treg](https://cancerworld.net/tag/treg/)
- [MDT](https://cancerworld.net/tag/mdt/)
- [pathology](https://cancerworld.net/tag/pathology/)
- [quality](https://cancerworld.net/tag/quality/)
- [European Code of Cancer Practice](https://cancerworld.net/tag/european-code-of-cancer-practice/)
- [outcomes](https://cancerworld.net/tag/outcomes/)
- [patient rights](https://cancerworld.net/tag/patient-rights/)
- [best practice](https://cancerworld.net/tag/best-practice/)
- [care](https://cancerworld.net/tag/care/)
- [communication](https://cancerworld.net/tag/communication/)
- [AKT inhibitor](https://cancerworld.net/tag/akt-inhibitor/)
- [combination therapy](https://cancerworld.net/tag/combination-therapy/)
- [PARP inhibitor](https://cancerworld.net/tag/parp-inhibitor/)
- [phase I study](https://cancerworld.net/tag/phase-i-study/)
- [AACR Cancer Progress Report](https://cancerworld.net/tag/aacr-cancer-progress-report/)
- [cancer health disparities](https://cancerworld.net/tag/cancer-health-disparities/)
- [Covid-19 pandemic](https://cancerworld.net/tag/covid-19-pandemic/)
- [death rates](https://cancerworld.net/tag/death-rates/)
- [racial or ethnic group](https://cancerworld.net/tag/racial-or-ethnic-group/)
- [actionable mutations](https://cancerworld.net/tag/actionable-mutations/)
- [Cancer of unknown primary](https://cancerworld.net/tag/cancer-of-unknown-primary/)
- [separate disease entity](https://cancerworld.net/tag/separate-disease-entity/)
- [tissue of origin](https://cancerworld.net/tag/tissue-of-origin/)
- [health professionals](https://cancerworld.net/tag/health-professionals/)
- [humanity](https://cancerworld.net/tag/humanity/)
- [interdisciplinarity](https://cancerworld.net/tag/interdisciplinarity/)
- [cervical cancer](https://cancerworld.net/tag/cervical-cancer/)
- [head and neck cancer](https://cancerworld.net/tag/head-and-neck-cancer/)
- [vaccination](https://cancerworld.net/tag/vaccination/)
- [Profession](https://cancerworld.net/tag/profession/)
- [Radiation Therapists](https://cancerworld.net/tag/radiation-therapists/)
- [Train the Trainers](https://cancerworld.net/tag/train-the-trainers/)
- [endpoints](https://cancerworld.net/tag/endpoints/)
- [telemedicine](https://cancerworld.net/tag/telemedicine/)
- [breast cancer prevention](https://cancerworld.net/tag/breast-cancer-prevention/)
- [Europa Donna](https://cancerworld.net/tag/europa-donna/)
- [European Union](https://cancerworld.net/tag/european-union/)
- [interdisciplinary research](https://cancerworld.net/tag/interdisciplinary-research/)
- [anti-virals](https://cancerworld.net/tag/anti-virals/)
- [nobel prize](https://cancerworld.net/tag/nobel-prize/)
- [virology](https://cancerworld.net/tag/virology/)
- [Virus](https://cancerworld.net/tag/virus/)
- [Bone metastases](https://cancerworld.net/tag/bone-metastases/)
- [Pathway](https://cancerworld.net/tag/pathway/)
- [radiotherapy](https://cancerworld.net/tag/radiotherapy/)
- [venous thromboembolism](https://cancerworld.net/tag/venous-thromboembolism/)
- [prophylaxis](https://cancerworld.net/tag/prophylaxis/)
- [cancer-associated thrombosis](https://cancerworld.net/tag/cancer-associated-thrombosis/)
- [Bleeding](https://cancerworld.net/tag/bleeding/)
- [Adverse events](https://cancerworld.net/tag/adverse-events/)
- [immunotherapy](https://cancerworld.net/tag/immunotherapy/)
- [patient-reported outcomes](https://cancerworld.net/tag/patient-reported-outcomes-2/)
- [PRO tools](https://cancerworld.net/tag/pro-tools/)
- [randomised clinical trials](https://cancerworld.net/tag/randomised-clinical-trials/)
- [Androgen-deprivation therapy](https://cancerworld.net/tag/androgen-deprivation-therapy-2/)
- [Cardiorespiratory fitness](https://cancerworld.net/tag/cardiorespiratory-fitness/)
- [Cardiovascular mortality](https://cancerworld.net/tag/cardiovascular-mortality/)
- [Cancer Services](https://cancerworld.net/tag/cancer-services/)
- [team meeting](https://cancerworld.net/tag/team-meeting/)
- [organisation](https://cancerworld.net/tag/organisation/)
- [blood test](https://cancerworld.net/tag/blood-test/)
- [early detection](https://cancerworld.net/tag/early-detection/)
- [grail](https://cancerworld.net/tag/grail/)
- [NHS](https://cancerworld.net/tag/nhs/)
- [combinations](https://cancerworld.net/tag/combinations/)
- [immunogenic cell death](https://cancerworld.net/tag/immunogenic-cell-death/)
- [oncolytic virus](https://cancerworld.net/tag/oncolytic-virus/)
- [drug development](https://cancerworld.net/tag/drug-development/)
- [European Medicines Agency](https://cancerworld.net/tag/european-medicines-agency/)
- [health technology assessment](https://cancerworld.net/tag/health-technology-assessment/)
- [MCBS](https://cancerworld.net/tag/mcbs/)
- [Heart toxicity](https://cancerworld.net/tag/heart-toxicity/)
- [PD1 inhibitors](https://cancerworld.net/tag/pd1-inhibitors/)
- [CTLA4 inhibitors](https://cancerworld.net/tag/ctla4-inhibitors/)
- [observational study](https://cancerworld.net/tag/observational-study/)
- [Adjuvant therapy](https://cancerworld.net/tag/adjuvant-therapy/)
- [circulating tumour cells](https://cancerworld.net/tag/circulating-tumour-cells/)
- [Subsequent primary](https://cancerworld.net/tag/subsequent-primary/)
- [behavioural interventions](https://cancerworld.net/tag/behavioural-interventions/)
- [depression](https://cancerworld.net/tag/depression/)
- [young women](https://cancerworld.net/tag/young-women/)
- [San Antonio Breast Cancer Symposium](https://cancerworld.net/tag/san-antonio-breast-cancer-symposium/)
- [advance](https://cancerworld.net/tag/advance/)
- [haematology](https://cancerworld.net/tag/haematology/)
- [geriatric](https://cancerworld.net/tag/geriatric/)
- [ovarian cancer](https://cancerworld.net/tag/ovarian-cancer/)
- [tumour biopsy](https://cancerworld.net/tag/tumour-biopsy/)
- [computed tomography](https://cancerworld.net/tag/computed-tomography/)
- [ultrasound](https://cancerworld.net/tag/ultrasound/)
- [radiomics](https://cancerworld.net/tag/radiomics/)
- [integrated approach](https://cancerworld.net/tag/integrated-approach/)
- [Financial toxicity](https://cancerworld.net/tag/financial-toxicity/)
- [advanced cancer](https://cancerworld.net/tag/advanced-cancer/)
- [health-related quality of life](https://cancerworld.net/tag/health-related-quality-of-life/)
- [anxiety](https://cancerworld.net/tag/anxiety/)
- [distress](https://cancerworld.net/tag/distress/)
- [screening tool](https://cancerworld.net/tag/screening-tool/)
- [caffeine](https://cancerworld.net/tag/caffeine/)
- [androgen receptors](https://cancerworld.net/tag/androgen-receptors/)
- [oestrogen receptor](https://cancerworld.net/tag/oestrogen-receptor/)
- [androgen receptor stimulating drugs](https://cancerworld.net/tag/androgen-receptor-stimulating-drugs/)
- [paediatric oncology](https://cancerworld.net/tag/paediatric-oncology/)
- [World Cancer Day](https://cancerworld.net/tag/world-cancer-day/)
- [genetic testing](https://cancerworld.net/tag/genetic-testing/)
- [Breast Cancer Association Consortium](https://cancerworld.net/tag/breast-cancer-association-consortium/)
- [boadicea](https://cancerworld.net/tag/boadicea/)
- [CARRIERS](https://cancerworld.net/tag/carriers/)
- [lifestyle](https://cancerworld.net/tag/lifestyle/)
- [Biparametric MRI](https://cancerworld.net/tag/biparametric-mri/)
- [multiparametric MRI](https://cancerworld.net/tag/multiparametric-mri/)
- [immunology](https://cancerworld.net/tag/immunology/)
- [natural killers](https://cancerworld.net/tag/natural-killers/)
- [CAR](https://cancerworld.net/tag/car/)
- [antitrust rules](https://cancerworld.net/tag/antitrust-rules/)
- [european commission](https://cancerworld.net/tag/european-commission/)
- [excessive pricing](https://cancerworld.net/tag/excessive-pricing/)
- [laboratory accreditation schemes](https://cancerworld.net/tag/laboratory-accreditation-schemes/)
- [EU27](https://cancerworld.net/tag/eu27/)
- [UK](https://cancerworld.net/tag/uk/)
- [navigator](https://cancerworld.net/tag/navigator/)
- [occupational cancer](https://cancerworld.net/tag/occupational-cancer/)
- [cancer journey](https://cancerworld.net/tag/cancer-journey/)
- [Africa](https://cancerworld.net/tag/africa/)
- [gene therapy](https://cancerworld.net/tag/gene-therapy/)
- [delivery](https://cancerworld.net/tag/delivery/)
- [solid tumours](https://cancerworld.net/tag/solid-tumours/)
- [Mammaprint](https://cancerworld.net/tag/mammaprint/)
- [MINDACT](https://cancerworld.net/tag/mindact/)
- [late diagnosis](https://cancerworld.net/tag/late-diagnosis/)
- [cardiovascular](https://cancerworld.net/tag/cardiovascular/)
- [geriatric oncology](https://cancerworld.net/tag/geriatric-oncology/)
- [regulators](https://cancerworld.net/tag/regulators/)
- [trials](https://cancerworld.net/tag/trials/)
- [frail](https://cancerworld.net/tag/frail/)
- [biomarker testing](https://cancerworld.net/tag/biomarker-testing/)
- [next-generation sequencing](https://cancerworld.net/tag/next-generation-sequencing-2/)
- [phosphoproteomics](https://cancerworld.net/tag/phosphoproteomics/)
- [proteomics](https://cancerworld.net/tag/proteomics/)
- [adjuvant treatment](https://cancerworld.net/tag/adjuvant-treatment/)
- [checkpoint inhibitor](https://cancerworld.net/tag/checkpoint-inhibitor/)
- [neoadjuvant treatment](https://cancerworld.net/tag/neoadjuvant-treatment/)
- [non-small cell lung cancer](https://cancerworld.net/tag/non-small-cell-lung-cancer/)
- [pathological complete response](https://cancerworld.net/tag/pathological-complete-response/)
- [aggressive prostate cancer](https://cancerworld.net/tag/aggressive-prostate-cancer/)
- [polygenetic risk scores](https://cancerworld.net/tag/polygenetic-risk-scores/)
- [NKX3.1 gene](https://cancerworld.net/tag/nkx3-1-gene/)
- [mpMRI](https://cancerworld.net/tag/mpmri/)
- [risk stratification](https://cancerworld.net/tag/risk-stratification/)
- [overtreatment](https://cancerworld.net/tag/overtreatment/)
- [Alzheimer’s disease](https://cancerworld.net/tag/alzheimers-disease/)
- [dopamine](https://cancerworld.net/tag/dopamine/)
- [sargramostim](https://cancerworld.net/tag/sargramostim/)
- [squamous skin cancers](https://cancerworld.net/tag/squamous-skin-cancers/)
- [Finnish National Cancer Registry](https://cancerworld.net/tag/finnish-national-cancer-registry/)
- [Kuopio Ischaemic Heart Disease Risk Factor Study](https://cancerworld.net/tag/kuopio-ischaemic-heart-disease-risk-factor-study/)
- [loneliness](https://cancerworld.net/tag/loneliness/)
- [social isolation](https://cancerworld.net/tag/social-isolation/)
- [cancer policy](https://cancerworld.net/tag/cancer-policy/)
- [CA125](https://cancerworld.net/tag/ca125/)
- [ovarian cancer screening](https://cancerworld.net/tag/ovarian-cancer-screening/)
- [risk algorithm](https://cancerworld.net/tag/risk-algorithm/)
- [transvaginal ultrasound](https://cancerworld.net/tag/transvaginal-ultrasound/)
- [UK Collaborative Trial of Ovarian Cancer screening study](https://cancerworld.net/tag/uk-collaborative-trial-of-ovarian-cancer-screening-study/)
- [chemotherapy toxicity risk calculator](https://cancerworld.net/tag/chemotherapy-toxicity-risk-calculator/)
- [functional age](https://cancerworld.net/tag/functional-age/)
- [geriatric assessment](https://cancerworld.net/tag/geriatric-assessment/)
- [Opioids](https://cancerworld.net/tag/opioids/)
- [morphine](https://cancerworld.net/tag/morphine/)
- [analgesics](https://cancerworld.net/tag/analgesics/)
- [commit to quit campaign](https://cancerworld.net/tag/commit-to-quit-campaign/)
- [lung cancer screening](https://cancerworld.net/tag/lung-cancer-screening/)
- [smoking cessation](https://cancerworld.net/tag/smoking-cessation/)
- [Tobacco Control Scale](https://cancerworld.net/tag/tobacco-control-scale/)
- [WHO Framework on Tobacco Control](https://cancerworld.net/tag/who-framework-on-tobacco-control/)
- [World No Tobacco Day](https://cancerworld.net/tag/world-no-tobacco-day/)
- [Quit Challenge](https://cancerworld.net/tag/quit-challenge/)
- [apalutamide](https://cancerworld.net/tag/apalutamide/)
- [docetaxel](https://cancerworld.net/tag/docetaxel/)
- [enzalutamide](https://cancerworld.net/tag/enzalutamide/)
- [metastatic castration sensitive prostate cancer](https://cancerworld.net/tag/metastatic-castration-sensitive-prostate-cancer/)
- [novel hormonal therapy](https://cancerworld.net/tag/novel-hormonal-therapy/)
- [out-reach education](https://cancerworld.net/tag/out-reach-education/)
- [racial disparities](https://cancerworld.net/tag/racial-disparities/)
- [real-world utilization](https://cancerworld.net/tag/real-world-utilization/)
- [Covid-19 recovery plan](https://cancerworld.net/tag/covid-19-recovery-plan/)
- [cancer surgery](https://cancerworld.net/tag/cancer-surgery/)
- [certification](https://cancerworld.net/tag/certification/)
- [Advance care planning](https://cancerworld.net/tag/advance-care-planning/)
- [advance directive](https://cancerworld.net/tag/advance-directive/)
- [end of life conversations](https://cancerworld.net/tag/end-of-life-conversations/)
- [herth hope index](https://cancerworld.net/tag/herth-hope-index/)
- [hope](https://cancerworld.net/tag/hope/)
- [living will](https://cancerworld.net/tag/living-will/)
- [supportive care](https://cancerworld.net/tag/supportive-care/)
- [ACE inhibitor](https://cancerworld.net/tag/ace-inhibitor/)
- [beta blocker](https://cancerworld.net/tag/beta-blocker/)
- [cardiotoxicity](https://cancerworld.net/tag/cardiotoxicity/)
- [carvedilol](https://cancerworld.net/tag/carvedilol/)
- [HER2 breast cancer](https://cancerworld.net/tag/her2-breast-cancer/)
- [lisinopril](https://cancerworld.net/tag/lisinopril/)
- [left ventricular ejection fraction](https://cancerworld.net/tag/left-ventricular-ejection-fraction/)
- [trastuzumab](https://cancerworld.net/tag/trastuzumab/)
- [risk of cancer](https://cancerworld.net/tag/risk-of-cancer/)
- [statins](https://cancerworld.net/tag/statins/)
- [Heart failure](https://cancerworld.net/tag/heart-failure/)
- [LDCT scanning](https://cancerworld.net/tag/ldct-scanning/)
- [implementation](https://cancerworld.net/tag/implementation/)
- [aspirin](https://cancerworld.net/tag/aspirin/)
- [survival](https://cancerworld.net/tag/survival/)
- [exercises](https://cancerworld.net/tag/exercises/)
- [gynaecological cancers](https://cancerworld.net/tag/gynaecological-cancers/)
- [health outcomes](https://cancerworld.net/tag/health-outcomes/)
- [social determinants of health](https://cancerworld.net/tag/social-determinants-of-health/)
- [LMIC](https://cancerworld.net/tag/lmic/)
- [latin america](https://cancerworld.net/tag/latin-america/)
- [BRCA2](https://cancerworld.net/tag/brca2/)
- [breast](https://cancerworld.net/tag/breast/)
- [ovarian](https://cancerworld.net/tag/ovarian/)
- [hereditary](https://cancerworld.net/tag/hereditary/)
- [backlog](https://cancerworld.net/tag/backlog/)
- [Time to Act campaign](https://cancerworld.net/tag/time-to-act-campaign/)
- [build back better](https://cancerworld.net/tag/build-back-better/)
- [Europe's Beating Cancer Plan](https://cancerworld.net/tag/europes-beating-cancer-plan/)
- [alcohol control](https://cancerworld.net/tag/alcohol-control/)
- [public health](https://cancerworld.net/tag/public-health/)
- [alcohol](https://cancerworld.net/tag/alcohol/)
- [Ketogenic diet](https://cancerworld.net/tag/ketogenic-diet/)
- [insulin](https://cancerworld.net/tag/insulin/)
- [radiosensitivity](https://cancerworld.net/tag/radiosensitivity/)
- [glioblastoma](https://cancerworld.net/tag/glioblastoma/)
- [oncology](https://cancerworld.net/tag/oncology/)
- [Antihypertensive](https://cancerworld.net/tag/antihypertensive/)
- [Angiotensin Converting Enzyme (ACE) inhibitor](https://cancerworld.net/tag/angiotensin-converting-enzyme-ace-inhibitor/)
- [Angiotensin Receptor Blockers (ARBs)](https://cancerworld.net/tag/angiotensin-receptor-blockers-arbs/)
- [Hypertension](https://cancerworld.net/tag/hypertension/)
- [Thiazide Diuretic](https://cancerworld.net/tag/thiazide-diuretic/)
- [Tumour Microenvironment](https://cancerworld.net/tag/tumour-microenvironment/)
- [active surveillance](https://cancerworld.net/tag/active-surveillance/)
- [treatment switching](https://cancerworld.net/tag/treatment-switching/)
- [watchful waiting](https://cancerworld.net/tag/watchful-waiting/)
- [Adriana Albini](https://cancerworld.net/tag/adriana-albini/)
- [Angiogenesis](https://cancerworld.net/tag/angiogenesis/)
- [anti-cancer drugs](https://cancerworld.net/tag/anti-cancer-drugs/)
- [marine](https://cancerworld.net/tag/marine/)
- [fatigue](https://cancerworld.net/tag/fatigue/)
- [symptoms](https://cancerworld.net/tag/symptoms/)
- [cytokines](https://cancerworld.net/tag/cytokines/)
- [Comprehensive Cancer Centres](https://cancerworld.net/tag/comprehensive-cancer-centres/)
- [Comprehensive Cancer Networks](https://cancerworld.net/tag/comprehensive-cancer-networks/)
- [OECI](https://cancerworld.net/tag/oeci/)
- [EU policy](https://cancerworld.net/tag/eu-policy/)
- [Europe’s Beating Cancer Plan](https://cancerworld.net/tag/europes-beating-cancer-plan-2/)
- [fertility preservation](https://cancerworld.net/tag/fertility-preservation/)
- [alkylating agents](https://cancerworld.net/tag/alkylating-agents/)
- [GnRH analogues](https://cancerworld.net/tag/gnrh-analogues/)
- [cryopreservation](https://cancerworld.net/tag/cryopreservation/)
- [ovarian tissue](https://cancerworld.net/tag/ovarian-tissue/)
- [oocytes](https://cancerworld.net/tag/oocytes/)
- [embryos](https://cancerworld.net/tag/embryos/)
- [assisted reproduction](https://cancerworld.net/tag/assisted-reproduction/)
- [medically assisted procreation](https://cancerworld.net/tag/medically-assisted-procreation/)
- [abiraterone acetate](https://cancerworld.net/tag/abiraterone-acetate/)
- [aromatase inhibitor](https://cancerworld.net/tag/aromatase-inhibitor/)
- [CDK4/6 inhibitor enzalutamide](https://cancerworld.net/tag/cdk4-6-inhibitor-enzalutamide/)
- [hormone-receptor-positive breast cancer](https://cancerworld.net/tag/hormone-receptor-positive-breast-cancer/)
- [letrozole](https://cancerworld.net/tag/letrozole/)
- [ribociclib](https://cancerworld.net/tag/ribociclib/)
- [tamoxifen](https://cancerworld.net/tag/tamoxifen/)
- [long-term effects](https://cancerworld.net/tag/long-term-effects/)
- [undertreatment](https://cancerworld.net/tag/undertreatment/)
- [CME](https://cancerworld.net/tag/cme/)
- [patient education](https://cancerworld.net/tag/patient-education/)
- [patient cancer knowledge](https://cancerworld.net/tag/patient-cancer-knowledge/)
- [long Covid](https://cancerworld.net/tag/long-covid/)
- [treatment discontinuation](https://cancerworld.net/tag/treatment-discontinuation/)
- [treatment adjustment](https://cancerworld.net/tag/treatment-adjustment/)
- [scientific method](https://cancerworld.net/tag/scientific-method/)
- [organoids](https://cancerworld.net/tag/organoids/)
- [model](https://cancerworld.net/tag/model/)
- [childhood cancer](https://cancerworld.net/tag/childhood-cancer/)
- [standards](https://cancerworld.net/tag/standards/)
- [protocols](https://cancerworld.net/tag/protocols/)
- [WHO Essential Medicines List](https://cancerworld.net/tag/who-essential-medicines-list/)
- [anti-inflammatory drugs](https://cancerworld.net/tag/anti-inflammatory-drugs/)
- [dexamethasone](https://cancerworld.net/tag/dexamethasone/)
- [non-immunogenic cancers](https://cancerworld.net/tag/non-immunogenic-cancers/)
- [non-small-cell lung cancer](https://cancerworld.net/tag/non-small-cell-lung-cancer-2/)
- [HER2](https://cancerworld.net/tag/her2/)
- [PD-L1](https://cancerworld.net/tag/pd-l1/)
- [adjuvant](https://cancerworld.net/tag/adjuvant/)
- [RAS](https://cancerworld.net/tag/ras/)
- [TP53](https://cancerworld.net/tag/tp53/)
- [umbrella trial](https://cancerworld.net/tag/umbrella-trial/)
- [sexual dimorphism](https://cancerworld.net/tag/sexual-dimorphism/)
- [incidence](https://cancerworld.net/tag/incidence/)
- [pharmacokinetics](https://cancerworld.net/tag/pharmacokinetics/)
- [biology](https://cancerworld.net/tag/biology/)
- [host](https://cancerworld.net/tag/host/)
- [dosing](https://cancerworld.net/tag/dosing/)
- [immune system](https://cancerworld.net/tag/immune-system/)
- [AL amyloidosis](https://cancerworld.net/tag/al-amyloidosis/)
- [Multiple myeloma](https://cancerworld.net/tag/multiple-myeloma/)
- [Myeloma Access Atlas Platform](https://cancerworld.net/tag/myeloma-access-atlas-platform/)
- [Myeloma Patients Europe](https://cancerworld.net/tag/myeloma-patients-europe/)
- [elderly](https://cancerworld.net/tag/elderly/)
- [decision tool](https://cancerworld.net/tag/decision-tool/)
- [National Cancer Institute](https://cancerworld.net/tag/national-cancer-institute/)
- [coordination](https://cancerworld.net/tag/coordination/)
- [Oligometastatic Renal Cell Carcinoma](https://cancerworld.net/tag/oligometastatic-renal-cell-carcinoma/)
- [Stereotactic body radiation therapy](https://cancerworld.net/tag/stereotactic-body-radiation-therapy/)
- [Ki67](https://cancerworld.net/tag/ki67/)
- [ESMO guidelines](https://cancerworld.net/tag/esmo-guidelines/)
- [metastatic breast cancer](https://cancerworld.net/tag/metastatic-breast-cancer/)
- [implementation trials](https://cancerworld.net/tag/implementation-trials/)
- [global health](https://cancerworld.net/tag/global-health/)
- [collaboration](https://cancerworld.net/tag/collaboration/)
- [cancer groundshot](https://cancerworld.net/tag/cancer-groundshot/)
- [LMICs](https://cancerworld.net/tag/lmics/)
- [Asia](https://cancerworld.net/tag/asia/)
- [oligometastases](https://cancerworld.net/tag/oligometastases/)
- [renal cell carcinoma](https://cancerworld.net/tag/renal-cell-carcinoma/)
- [recovery](https://cancerworld.net/tag/recovery/)
- [resilience](https://cancerworld.net/tag/resilience/)
- [data](https://cancerworld.net/tag/data/)
- [health system](https://cancerworld.net/tag/health-system/)
- [health systems](https://cancerworld.net/tag/health-systems/)
- [teenage and young adults](https://cancerworld.net/tag/teenage-and-young-adults/)
- [cancer treatment](https://cancerworld.net/tag/cancer-treatment/)
- [primary care](https://cancerworld.net/tag/primary-care/)
- [hospitalisation](https://cancerworld.net/tag/hospitalisation/)
- [cancer late effects](https://cancerworld.net/tag/cancer-late-effects/)
- [years of life lost](https://cancerworld.net/tag/years-of-life-lost/)
- [central and eastern Europe](https://cancerworld.net/tag/central-and-eastern-europe/)
- [cytotoxics](https://cancerworld.net/tag/cytotoxics/)
- [obesity](https://cancerworld.net/tag/obesity/)
- [liver disease](https://cancerworld.net/tag/liver-disease/)
- [surveillance](https://cancerworld.net/tag/surveillance/)
- [standard of care](https://cancerworld.net/tag/standard-of-care/)
- [anti-PD-1/PD-L1 treatment](https://cancerworld.net/tag/anti-pd-1-pd-l1-treatment/)
- [histamine](https://cancerworld.net/tag/histamine/)
- [histamine receptors](https://cancerworld.net/tag/histamine-receptors/)
- [macrophages](https://cancerworld.net/tag/macrophages/)
- [arm disability](https://cancerworld.net/tag/arm-disability/)
- [physiotherapy](https://cancerworld.net/tag/physiotherapy/)
- [lymphoedema](https://cancerworld.net/tag/lymphoedema/)
- [carers](https://cancerworld.net/tag/carers/)
- [workers’ rights](https://cancerworld.net/tag/workers-rights/)
- [psychological support](https://cancerworld.net/tag/psychological-support/)
- [health insurance](https://cancerworld.net/tag/health-insurance/)
- [hepatocellular carcinoma](https://cancerworld.net/tag/hepatocellular-carcinoma/)
- [hepatology](https://cancerworld.net/tag/hepatology/)
- [doctor-patient relationship](https://cancerworld.net/tag/doctor-patient-relationship/)
- [bedside manner](https://cancerworld.net/tag/bedside-manner/)
- [gemcitabine](https://cancerworld.net/tag/gemcitabine/)
- [endocrine resistance](https://cancerworld.net/tag/endocrine-resistance/)
- [castration resistant prostate cancer](https://cancerworld.net/tag/castration-resistant-prostate-cancer/)
- [probiotics](https://cancerworld.net/tag/probiotics/)
- [academic oncologists](https://cancerworld.net/tag/academic-oncologists/)
- [job prospects](https://cancerworld.net/tag/job-prospects/)
- [fibre](https://cancerworld.net/tag/fibre/)
- [ruminococcaceae](https://cancerworld.net/tag/ruminococcaceae/)
- [population screening](https://cancerworld.net/tag/population-screening/)
- [low-dose CT](https://cancerworld.net/tag/low-dose-ct/)
- [sitting](https://cancerworld.net/tag/sitting/)
- [leisure-time physical activity](https://cancerworld.net/tag/leisure-time-physical-activity/)
- [inactivity](https://cancerworld.net/tag/inactivity/)
- [sedentary behaviour](https://cancerworld.net/tag/sedentary-behaviour/)
- [CCAAT/ enhancer-binding protein beta](https://cancerworld.net/tag/ccaat-enhancer-binding-protein-beta/)
- [CLDN1](https://cancerworld.net/tag/cldn1/)
- [hormone receptor negative breast cancer](https://cancerworld.net/tag/hormone-receptor-negative-breast-cancer/)
- [LCN2](https://cancerworld.net/tag/lcn2/)
- [palmitic acid](https://cancerworld.net/tag/palmitic-acid/)
- [mechanism of action](https://cancerworld.net/tag/mechanism-of-action/)
- [transparency](https://cancerworld.net/tag/transparency/)
- [patient pathways](https://cancerworld.net/tag/patient-pathways/)
- [innovation](https://cancerworld.net/tag/innovation/)
- [prehabilitation](https://cancerworld.net/tag/prehabilitation/)
- [downstaging](https://cancerworld.net/tag/downstaging/)
- [fat-to-muscle ratio](https://cancerworld.net/tag/fat-to-muscle-ratio/)
- [neoadjuvant chemotherapy](https://cancerworld.net/tag/neoadjuvant-chemotherapy/)
- [oesophageal cancer](https://cancerworld.net/tag/oesophageal-cancer/)
- [sarcopenia](https://cancerworld.net/tag/sarcopenia/)
- [tumour regression](https://cancerworld.net/tag/tumour-regression/)
- [cancer genomics](https://cancerworld.net/tag/cancer-genomics/)
- [cell lines](https://cancerworld.net/tag/cell-lines/)
- [citizen science](https://cancerworld.net/tag/citizen-science/)
- [human genome](https://cancerworld.net/tag/human-genome/)
- [video games](https://cancerworld.net/tag/video-games/)
- [chemobrain](https://cancerworld.net/tag/chemobrain/)
- [cognitive impairment](https://cancerworld.net/tag/cognitive-impairment/)
- [leadership](https://cancerworld.net/tag/leadership/)
- [mentors](https://cancerworld.net/tag/mentors/)
- [Cancer disparities](https://cancerworld.net/tag/cancer-disparities/)
- [cancer screening](https://cancerworld.net/tag/cancer-screening/)
- [congress](https://cancerworld.net/tag/congress/)
- [Anastrozole](https://cancerworld.net/tag/anastrozole/)
- [aromatase inhibitors](https://cancerworld.net/tag/aromatase-inhibitors/)
- [exemestane](https://cancerworld.net/tag/exemestane/)
- [premenopausal women](https://cancerworld.net/tag/premenopausal-women/)
- [academic](https://cancerworld.net/tag/academic/)
- [ATM](https://cancerworld.net/tag/atm/)
- [CHK2](https://cancerworld.net/tag/chk2/)
- [CISNET](https://cancerworld.net/tag/cisnet/)
- [mammography](https://cancerworld.net/tag/mammography/)
- [MRI](https://cancerworld.net/tag/mri/)
- [PALB2](https://cancerworld.net/tag/palb2/)
- [Lachnospiraceae species](https://cancerworld.net/tag/lachnospiraceae-species/)
- [Streptococcaceae species](https://cancerworld.net/tag/streptococcaceae-species/)
- [transkingdom network analysis](https://cancerworld.net/tag/transkingdom-network-analysis/)
- [psycho-oncology](https://cancerworld.net/tag/psycho-oncology/)
- [psychosocial](https://cancerworld.net/tag/psychosocial/)
- [Ukraine](https://cancerworld.net/tag/ukraine/)
- [humanitarian](https://cancerworld.net/tag/humanitarian/)
- [support](https://cancerworld.net/tag/support/)
- [anti PD-1](https://cancerworld.net/tag/anti-pd-1/)
- [antibiotics](https://cancerworld.net/tag/antibiotics/)
- [anti-PD-1 antibody](https://cancerworld.net/tag/anti-pd-1-antibody/)
- [gut microbiome](https://cancerworld.net/tag/gut-microbiome/)
- [immune checkpoint inhibitors](https://cancerworld.net/tag/immune-checkpoint-inhibitors/)
- [Systéme National des Données de Santé](https://cancerworld.net/tag/systeme-national-des-donnees-de-sante/)
- [American Society of Clinical Oncology (ASCO)](https://cancerworld.net/tag/american-society-of-clinical-oncology-asco/)
- [cancer patient refugees](https://cancerworld.net/tag/cancer-patient-refugees/)
- [war in Ukraine](https://cancerworld.net/tag/war-in-ukraine/)
- [molecular diagnostics](https://cancerworld.net/tag/molecular-diagnostics/)
- [molecular tumour boards](https://cancerworld.net/tag/molecular-tumour-boards/)
- [liquid biopsy](https://cancerworld.net/tag/liquid-biopsy/)
- [equal access](https://cancerworld.net/tag/equal-access/)
- [patents](https://cancerworld.net/tag/patents/)
- [intellectual property rights](https://cancerworld.net/tag/intellectual-property-rights/)
- [history](https://cancerworld.net/tag/history/)
- [cumulative life-time exposure](https://cancerworld.net/tag/cumulative-life-time-exposure/)
- [overweight](https://cancerworld.net/tag/overweight/)
- [breast arterial calcification](https://cancerworld.net/tag/breast-arterial-calcification/)
- [cardiovascular disease risk](https://cancerworld.net/tag/cardiovascular-disease-risk/)
- [coronary artery calcification](https://cancerworld.net/tag/coronary-artery-calcification/)
- [elimination](https://cancerworld.net/tag/elimination/)
- [HPV tests](https://cancerworld.net/tag/hpv-tests/)
- [Pap smear](https://cancerworld.net/tag/pap-smear/)
- [indicators](https://cancerworld.net/tag/indicators/)
- [universal health coverage](https://cancerworld.net/tag/universal-health-coverage/)
- [World Health Organization](https://cancerworld.net/tag/world-health-organization/)
- [brain tumour](https://cancerworld.net/tag/brain-tumour/)
- [glioma](https://cancerworld.net/tag/glioma/)
- [meningioma](https://cancerworld.net/tag/meningioma/)
- [mobile phone](https://cancerworld.net/tag/mobile-phone/)
- [pituitary tumour](https://cancerworld.net/tag/pituitary-tumour/)
- [radiofrequency electromagnetic fields](https://cancerworld.net/tag/radiofrequency-electromagnetic-fields/)
- [vaccination hesitancyy](https://cancerworld.net/tag/vaccination-hesitancyy/)
- [Cancer Plan](https://cancerworld.net/tag/cancer-plan/)
- [medical oncology](https://cancerworld.net/tag/medical-oncology/)
- [solidarity](https://cancerworld.net/tag/solidarity/)
- [war](https://cancerworld.net/tag/war/)
- [acoustic neuroma](https://cancerworld.net/tag/acoustic-neuroma/)
- [healthcare](https://cancerworld.net/tag/healthcare/)
- [reconstruction](https://cancerworld.net/tag/reconstruction/)
- [BNT211](https://cancerworld.net/tag/bnt211/)
- [CARVac](https://cancerworld.net/tag/carvac/)
- [claudin-6](https://cancerworld.net/tag/claudin-6/)
- [testicular cancer](https://cancerworld.net/tag/testicular-cancer/)
- [bowel cancer](https://cancerworld.net/tag/bowel-cancer/)
- [colon cancer](https://cancerworld.net/tag/colon-cancer/)
- [DNA damage](https://cancerworld.net/tag/dna-damage/)
- [IL-6](https://cancerworld.net/tag/il-6/)
- [mutational signatures](https://cancerworld.net/tag/mutational-signatures/)
- [100000 Genomes Cancer Project](https://cancerworld.net/tag/100000-genomes-cancer-project/)
- [Genomics England](https://cancerworld.net/tag/genomics-england/)
- [FitMS](https://cancerworld.net/tag/fitms/)
- [stress](https://cancerworld.net/tag/stress/)
- [drivers](https://cancerworld.net/tag/drivers/)
- [sri lanka](https://cancerworld.net/tag/sri-lanka/)
- [cardiomyopathy](https://cancerworld.net/tag/cardiomyopathy/)
- [doxorubicin](https://cancerworld.net/tag/doxorubicin/)
- [human induced pluripotent stem cells](https://cancerworld.net/tag/human-induced-pluripotent-stem-cells/)
- [multi organ chip](https://cancerworld.net/tag/multi-organ-chip/)
- [hormone receptors](https://cancerworld.net/tag/hormone-receptors/)
- [lumpectomy](https://cancerworld.net/tag/lumpectomy/)
- [mastectomy](https://cancerworld.net/tag/mastectomy/)
- [breast conserving surgery](https://cancerworld.net/tag/breast-conserving-surgery/)
- [mRNA vaccines](https://cancerworld.net/tag/mrna-vaccines/)
- [Vitamin D](https://cancerworld.net/tag/vitamin-d/)
- [omega-3](https://cancerworld.net/tag/omega-3/)
- [screening strategies](https://cancerworld.net/tag/screening-strategies/)
- [endoscopy](https://cancerworld.net/tag/endoscopy/)
- [race](https://cancerworld.net/tag/race/)
- [quality control](https://cancerworld.net/tag/quality-control/)
- [Ireland](https://cancerworld.net/tag/ireland/)
- [adherence](https://cancerworld.net/tag/adherence/)
- [psychosocial support](https://cancerworld.net/tag/psychosocial-support/)
- [culture](https://cancerworld.net/tag/culture/)
- [recognition](https://cancerworld.net/tag/recognition/)
- [opportunity](https://cancerworld.net/tag/opportunity/)
- [diabetes](https://cancerworld.net/tag/diabetes/)
- [extracellular vesicles](https://cancerworld.net/tag/extracellular-vesicles/)
- [miR-122](https://cancerworld.net/tag/mir-122/)
- [antibody drug conjugates](https://cancerworld.net/tag/antibody-drug-conjugates/)
- [patritumab deruxtecan](https://cancerworld.net/tag/patritumab-deruxtecan/)
- [trastuzumab deruxtecan](https://cancerworld.net/tag/trastuzumab-deruxtecan/)
- [India](https://cancerworld.net/tag/india/)
- [patient support group](https://cancerworld.net/tag/patient-support-group/)
- [GDPR](https://cancerworld.net/tag/gdpr/)
- [data privacy](https://cancerworld.net/tag/data-privacy/)
- [chromosomal instability](https://cancerworld.net/tag/chromosomal-instability/)
- [single nucleotide polymorphisms](https://cancerworld.net/tag/single-nucleotide-polymorphisms/)
- [breast density](https://cancerworld.net/tag/breast-density/)
- [digital breast tomosynthesis](https://cancerworld.net/tag/digital-breast-tomosynthesis/)
- [breast cancer risk](https://cancerworld.net/tag/breast-cancer-risk/)
- [digital mammography](https://cancerworld.net/tag/digital-mammography/)
- [circulating tumour DNA](https://cancerworld.net/tag/circulating-tumour-dna/)
- [hormone receptor positive breast cancer](https://cancerworld.net/tag/hormone-receptor-positive-breast-cancer-2/)
- [late adjuvant setting](https://cancerworld.net/tag/late-adjuvant-setting/)
- [minimal residual disease](https://cancerworld.net/tag/minimal-residual-disease/)
- [recurrence](https://cancerworld.net/tag/recurrence/)
- [survivorship](https://cancerworld.net/tag/survivorship/)
- [preclinical](https://cancerworld.net/tag/preclinical/)
- [PROMs](https://cancerworld.net/tag/proms/)
- [cancer therapies](https://cancerworld.net/tag/cancer-therapies/)
- [aid](https://cancerworld.net/tag/aid/)
- [cancer care capacity](https://cancerworld.net/tag/cancer-care-capacity/)
- [coronary artery disease](https://cancerworld.net/tag/coronary-artery-disease/)
- [stroke](https://cancerworld.net/tag/stroke/)
- [imatinib](https://cancerworld.net/tag/imatinib/)
- [Universal healthcare](https://cancerworld.net/tag/universal-healthcare/)
- [equity](https://cancerworld.net/tag/equity/)
- [generics](https://cancerworld.net/tag/generics/)
- [ethics](https://cancerworld.net/tag/ethics/)
- [CAPS programme](https://cancerworld.net/tag/caps-programme/)
- [Dutch Familial Pancreatic Surveillance](https://cancerworld.net/tag/dutch-familial-pancreatic-surveillance/)
- [pancreatic cancer screening](https://cancerworld.net/tag/pancreatic-cancer-screening/)
- [NICE](https://cancerworld.net/tag/nice/)
- [Poland](https://cancerworld.net/tag/poland/)
- [medical records](https://cancerworld.net/tag/medical-records/)
- [circle tool](https://cancerworld.net/tag/circle-tool/)
- [immune checkpoint blockade](https://cancerworld.net/tag/immune-checkpoint-blockade/)
- [whole exome sequencing](https://cancerworld.net/tag/whole-exome-sequencing/)
- [prediction](https://cancerworld.net/tag/prediction/)
- [response](https://cancerworld.net/tag/response/)
- [CML](https://cancerworld.net/tag/cml/)
- [skills](https://cancerworld.net/tag/skills/)
- [collagen](https://cancerworld.net/tag/collagen/)
- [DNA methylation](https://cancerworld.net/tag/dna-methylation/)
- [fibroblasts](https://cancerworld.net/tag/fibroblasts/)
- [pancreatic cancer](https://cancerworld.net/tag/pancreatic-cancer/)
- [tumour microbiome](https://cancerworld.net/tag/tumour-microbiome/)
- [bile acids](https://cancerworld.net/tag/bile-acids/)
- [CAPP2 trial](https://cancerworld.net/tag/capp2-trial/)
- [fermentable fibre](https://cancerworld.net/tag/fermentable-fibre/)
- [lynch syndrome](https://cancerworld.net/tag/lynch-syndrome/)
- [resistant starch](https://cancerworld.net/tag/resistant-starch/)
- [upper gastrointestinal cancers](https://cancerworld.net/tag/upper-gastrointestinal-cancers/)
- [Anti-inflammatories](https://cancerworld.net/tag/anti-inflammatories/)
- [endometriosis](https://cancerworld.net/tag/endometriosis/)
- [high grade serous ovarian cancer](https://cancerworld.net/tag/high-grade-serous-ovarian-cancer/)
- [inflammation](https://cancerworld.net/tag/inflammation/)
- [ovarian cancer risk](https://cancerworld.net/tag/ovarian-cancer-risk/)
- [screening programme](https://cancerworld.net/tag/screening-programme/)
- [rural](https://cancerworld.net/tag/rural/)
- [treatment selection](https://cancerworld.net/tag/treatment-selection/)
- [clinical decision medicine](https://cancerworld.net/tag/clinical-decision-medicine/)
- [cancer risk](https://cancerworld.net/tag/cancer-risk/)
- [fitness](https://cancerworld.net/tag/fitness/)
- [exercise support services](https://cancerworld.net/tag/exercise-support-services/)
- [nutrition support services](https://cancerworld.net/tag/nutrition-support-services/)
- [alveolar type 2 cells](https://cancerworld.net/tag/alveolar-type-2-cells/)
- [fossil fuel](https://cancerworld.net/tag/fossil-fuel/)
- [low dose computed tomography](https://cancerworld.net/tag/low-dose-computed-tomography/)
- [particulate matter](https://cancerworld.net/tag/particulate-matter/)
- [multicancer early detection](https://cancerworld.net/tag/multicancer-early-detection/)
- [Pathfinder study](https://cancerworld.net/tag/pathfinder-study/)
- [Galleri® test](https://cancerworld.net/tag/galleri-test/)
- [diagnostic](https://cancerworld.net/tag/diagnostic/)
- [imaging](https://cancerworld.net/tag/imaging/)
- [digital pathology](https://cancerworld.net/tag/digital-pathology/)
- [cancer plans](https://cancerworld.net/tag/cancer-plans/)
- [delayed diagnosis](https://cancerworld.net/tag/delayed-diagnosis/)
- [monoclonal gammopathy of undetermined significance](https://cancerworld.net/tag/monoclonal-gammopathy-of-undetermined-significance/)
- [myeloma](https://cancerworld.net/tag/myeloma/)
- [refugee](https://cancerworld.net/tag/refugee/)
- [refugees](https://cancerworld.net/tag/refugees/)
- [referral](https://cancerworld.net/tag/referral/)
- [conflict](https://cancerworld.net/tag/conflict/)
- [Syria](https://cancerworld.net/tag/syria/)
- [Turkey](https://cancerworld.net/tag/turkey/)
- [gadolinium](https://cancerworld.net/tag/gadolinium/)
- [resting membrane potential](https://cancerworld.net/tag/resting-membrane-potential/)
- [sodium leak channel non-selective protein](https://cancerworld.net/tag/sodium-leak-channel-non-selective-protein/)
- [tissue regeneration](https://cancerworld.net/tag/tissue-regeneration/)
- [basic science](https://cancerworld.net/tag/basic-science/)
- [oncolytic viruses](https://cancerworld.net/tag/oncolytic-viruses/)
- [translational science](https://cancerworld.net/tag/translational-science/)
- [BRAF-mutated melanoma](https://cancerworld.net/tag/braf-mutated-melanoma/)
- [DREAMseq](https://cancerworld.net/tag/dreamseq/)
- [immune therapy](https://cancerworld.net/tag/immune-therapy/)
- [metastatic melanoma](https://cancerworld.net/tag/metastatic-melanoma/)
- [neo adjuvant treatment](https://cancerworld.net/tag/neo-adjuvant-treatment/)
- [targeted therapy](https://cancerworld.net/tag/targeted-therapy/)
- [treatment sequence](https://cancerworld.net/tag/treatment-sequence/)
- [fungi](https://cancerworld.net/tag/fungi/)
- [bacteria](https://cancerworld.net/tag/bacteria/)
- [Blastomyces](https://cancerworld.net/tag/blastomyces/)
- [Candida tropicalis](https://cancerworld.net/tag/candida-tropicalis/)
- [Malassezia](https://cancerworld.net/tag/malassezia/)
- [mould](https://cancerworld.net/tag/mould/)
- [mycobiome](https://cancerworld.net/tag/mycobiome/)
- [prognostic](https://cancerworld.net/tag/prognostic/)
- [telementoring](https://cancerworld.net/tag/telementoring/)
- [service delivery](https://cancerworld.net/tag/service-delivery/)
- [fertility services](https://cancerworld.net/tag/fertility-services/)
- [reimbursement](https://cancerworld.net/tag/reimbursement/)
- [asymptomatic bone metastases](https://cancerworld.net/tag/asymptomatic-bone-metastases/)
- [hospitalisations](https://cancerworld.net/tag/hospitalisations/)
- [palliative radiotherapy](https://cancerworld.net/tag/palliative-radiotherapy/)
- [skeletal related events](https://cancerworld.net/tag/skeletal-related-events/)
- [MHC-IIb](https://cancerworld.net/tag/mhc-iib/)
- [MHC-IIx](https://cancerworld.net/tag/mhc-iix/)
- [nilotinib](https://cancerworld.net/tag/nilotinib/)
- [p38 MAK](https://cancerworld.net/tag/p38-mak/)
- [transcription factor C/EBP](https://cancerworld.net/tag/transcription-factor-c-ebp/)
- [UBR2](https://cancerworld.net/tag/ubr2/)
- [tobacco prevention](https://cancerworld.net/tag/tobacco-prevention/)
- [tobacco regulation](https://cancerworld.net/tag/tobacco-regulation/)
- [WHO Framework Convention on Tobacco Control](https://cancerworld.net/tag/who-framework-convention-on-tobacco-control/)
- [Eastern Europe](https://cancerworld.net/tag/eastern-europe/)
- [secondary prevention](https://cancerworld.net/tag/secondary-prevention/)
- [NCDs](https://cancerworld.net/tag/ncds/)
- [walking](https://cancerworld.net/tag/walking/)
- [Essential cancer medicines](https://cancerworld.net/tag/essential-cancer-medicines/)
- [Medicines Patent Pool](https://cancerworld.net/tag/medicines-patent-pool/)
- [life expectancy](https://cancerworld.net/tag/life-expectancy/)
- [functional prognosis](https://cancerworld.net/tag/functional-prognosis/)
- [prognostic preference](https://cancerworld.net/tag/prognostic-preference/)
- [nanomedicines](https://cancerworld.net/tag/nanomedicines/)
- [nanotechnology](https://cancerworld.net/tag/nanotechnology/)
- [immunogenicity](https://cancerworld.net/tag/immunogenicity/)
- [targeting](https://cancerworld.net/tag/targeting/)
- [apparent diffusion coefficient](https://cancerworld.net/tag/apparent-diffusion-coefficient/)
- [post-menopausal women](https://cancerworld.net/tag/post-menopausal-women/)
- [Black clinicians](https://cancerworld.net/tag/black-clinicians/)
- [Black researchers](https://cancerworld.net/tag/black-researchers/)
- [Black advocates](https://cancerworld.net/tag/black-advocates/)
- [inequalities](https://cancerworld.net/tag/inequalities/)
- [quality cancer care](https://cancerworld.net/tag/quality-cancer-care/)
- [Comprehensive cancer centre networks](https://cancerworld.net/tag/comprehensive-cancer-centre-networks/)
- [European Health Data Space](https://cancerworld.net/tag/european-health-data-space/)
- [data sharing](https://cancerworld.net/tag/data-sharing/)
- [co-creation](https://cancerworld.net/tag/co-creation/)
- [privacy](https://cancerworld.net/tag/privacy/)
- [big data](https://cancerworld.net/tag/big-data/)
- [electronic health records](https://cancerworld.net/tag/electronic-health-records/)
- [cross-border healthcare](https://cancerworld.net/tag/cross-border-healthcare/)
- [aerobic activity](https://cancerworld.net/tag/aerobic-activity/)
- [glucose consumption](https://cancerworld.net/tag/glucose-consumption/)
- [high-intensity exercise](https://cancerworld.net/tag/high-intensity-exercise/)
- [vaccination programme](https://cancerworld.net/tag/vaccination-programme/)
- [gender-neutral](https://cancerworld.net/tag/gender-neutral/)
- [stigma](https://cancerworld.net/tag/stigma/)
- [discrimination](https://cancerworld.net/tag/discrimination/)
- [fear of recurrence](https://cancerworld.net/tag/fear-of-recurrence/)
- [end of treatment](https://cancerworld.net/tag/end-of-treatment/)
- [follow-up](https://cancerworld.net/tag/follow-up/)
- [validation](https://cancerworld.net/tag/validation/)
- [-adrenergic blockade](https://cancerworld.net/tag/adrenergic-blockade/)
- [COX-2 inhibition](https://cancerworld.net/tag/cox-2-inhibition/)
- [etodolac propranolol](https://cancerworld.net/tag/etodolac-propranolol/)
- [interruption of endocrine therapy for pregnancy](https://cancerworld.net/tag/interruption-of-endocrine-therapy-for-pregnancy/)
- [tumour microenvironment of metastasis doorways](https://cancerworld.net/tag/tumour-microenvironment-of-metastasis-doorways/)
- [neoadjuivant chemotherapy](https://cancerworld.net/tag/neoadjuivant-chemotherapy/)
- [axillary lymph node dissection](https://cancerworld.net/tag/axillary-lymph-node-dissection/)
- [sentinel node biopsy](https://cancerworld.net/tag/sentinel-node-biopsy/)
- [cancer moonshot](https://cancerworld.net/tag/cancer-moonshot/)
- [proteogenomics](https://cancerworld.net/tag/proteogenomics/)
- [advanced prostate cancer](https://cancerworld.net/tag/advanced-prostate-cancer/)
- [exercise oncology](https://cancerworld.net/tag/exercise-oncology/)
- [myokines](https://cancerworld.net/tag/myokines/)
- [metastatic castrate-resistant prostate cancer](https://cancerworld.net/tag/metastatic-castrate-resistant-prostate-cancer/)
- [European Society for Paediatric Oncology](https://cancerworld.net/tag/european-society-for-paediatric-oncology/)
- [health technology assessments](https://cancerworld.net/tag/health-technology-assessments/)
- [cervical cancer elimination](https://cancerworld.net/tag/cervical-cancer-elimination/)
- [thermal ablation](https://cancerworld.net/tag/thermal-ablation/)
- [pre-cancerous lesions](https://cancerworld.net/tag/pre-cancerous-lesions/)
- [WHO Model list of Essential medicines for children](https://cancerworld.net/tag/who-model-list-of-essential-medicines-for-children/)
- [SIOPE](https://cancerworld.net/tag/siope/)
- [ultra low-dose immunotherapy](https://cancerworld.net/tag/ultra-low-dose-immunotherapy/)
- [de-escalation](https://cancerworld.net/tag/de-escalation/)
- [affordability](https://cancerworld.net/tag/affordability/)
- [cervix](https://cancerworld.net/tag/cervix/)
- [cervical cancer awareness month](https://cancerworld.net/tag/cervical-cancer-awareness-month/)
- [cervical cancer screening](https://cancerworld.net/tag/cervical-cancer-screening/)
- [human papillomavirus](https://cancerworld.net/tag/human-papillomavirus/)
- [pap test](https://cancerworld.net/tag/pap-test/)
- [Mexico](https://cancerworld.net/tag/mexico/)
- [public health insurance](https://cancerworld.net/tag/public-health-insurance/)
- [procurement](https://cancerworld.net/tag/procurement/)
- [distribution](https://cancerworld.net/tag/distribution/)
- [aurora](https://cancerworld.net/tag/aurora/)
- [dna clonality shift](https://cancerworld.net/tag/dna-clonality-shift/)
- [HER2 receptor](https://cancerworld.net/tag/her2-receptor/)
- [human leukocyte antigen](https://cancerworld.net/tag/human-leukocyte-antigen/)
- [progesterone receptor](https://cancerworld.net/tag/progesterone-receptor/)
- [heterogeneity](https://cancerworld.net/tag/heterogeneity/)
- [clonal mutation](https://cancerworld.net/tag/clonal-mutation/)
- [age](https://cancerworld.net/tag/age/)
- [St Gallen conferences](https://cancerworld.net/tag/st-gallen-conferences/)
- [MASCC](https://cancerworld.net/tag/mascc/)
- [early breast cancer](https://cancerworld.net/tag/early-breast-cancer/)
- [European School of Oncology](https://cancerworld.net/tag/european-school-of-oncology/)
- [type 2 diabetes](https://cancerworld.net/tag/type-2-diabetes/)
- [endometrial cancer](https://cancerworld.net/tag/endometrial-cancer/)
- [epithelial ovarian cancer](https://cancerworld.net/tag/epithelial-ovarian-cancer/)
- [mucinous epithelial ovarian cancer](https://cancerworld.net/tag/mucinous-epithelial-ovarian-cancer/)
- [ovulation](https://cancerworld.net/tag/ovulation/)
- [lifetime ovulation years](https://cancerworld.net/tag/lifetime-ovulation-years/)
- [oral contraceptives](https://cancerworld.net/tag/oral-contraceptives/)
- [breastfeeding](https://cancerworld.net/tag/breastfeeding/)
- [case-control study](https://cancerworld.net/tag/case-control-study/)
- [pooled analysis](https://cancerworld.net/tag/pooled-analysis/)
- [global access](https://cancerworld.net/tag/global-access/)
- [gloabal initiative for childhood cancer](https://cancerworld.net/tag/gloabal-initiative-for-childhood-cancer/)
- [malnutrition](https://cancerworld.net/tag/malnutrition/)
- [food insecurity](https://cancerworld.net/tag/food-insecurity/)
- [socioeconomic disparities](https://cancerworld.net/tag/socioeconomic-disparities/)
- [intervetion](https://cancerworld.net/tag/intervetion/)
- [waiting times/delays](https://cancerworld.net/tag/waiting-times-delays/)
- [medical migration](https://cancerworld.net/tag/medical-migration/)
- [facilities](https://cancerworld.net/tag/facilities/)
- [hospitals](https://cancerworld.net/tag/hospitals/)
- [autophagy](https://cancerworld.net/tag/autophagy/)
- [crisis](https://cancerworld.net/tag/crisis/)
- [mithocondria](https://cancerworld.net/tag/mithocondria/)
- [telomere](https://cancerworld.net/tag/telomere/)
- [mitochondrial antiviral-signalling protein (MAVS)](https://cancerworld.net/tag/mitochondrial-antiviral-signalling-protein-mavs/)
- [Z-DNA binding protein 1 (ZBP1)](https://cancerworld.net/tag/z-dna-binding-protein-1-zbp1/)
- [precancer](https://cancerworld.net/tag/precancer/)
- [suppression](https://cancerworld.net/tag/suppression/)
- [sensitivity](https://cancerworld.net/tag/sensitivity/)
- [specificity](https://cancerworld.net/tag/specificity/)
- [prostate specific antigen test](https://cancerworld.net/tag/prostate-specific-antigen-test/)
- [plan- based diets](https://cancerworld.net/tag/plan-based-diets/)
- [healthful plant based index](https://cancerworld.net/tag/healthful-plant-based-index/)
- [prostate cancer progression](https://cancerworld.net/tag/prostate-cancer-progression/)
- [distant recurrence](https://cancerworld.net/tag/distant-recurrence/)
- [local recurrence](https://cancerworld.net/tag/local-recurrence/)
- [overall survival](https://cancerworld.net/tag/overall-survival/)
- [omission of radiotherapy](https://cancerworld.net/tag/omission-of-radiotherapy/)
- [heart disease](https://cancerworld.net/tag/heart-disease/)
- [secondary cancers](https://cancerworld.net/tag/secondary-cancers/)
- [efficacy](https://cancerworld.net/tag/efficacy/)
- [selection](https://cancerworld.net/tag/selection/)
- [Mediterranean diet](https://cancerworld.net/tag/mediterranean-diet/)
- [dendritic cells](https://cancerworld.net/tag/dendritic-cells/)
- [CD5+](https://cancerworld.net/tag/cd5-2/)
- [virtual reality](https://cancerworld.net/tag/virtual-reality/)
- [digital](https://cancerworld.net/tag/digital/)
- [remote](https://cancerworld.net/tag/remote/)
- [cost-effectiveness](https://cancerworld.net/tag/cost-effectiveness/)
- [curriculum](https://cancerworld.net/tag/curriculum/)
- [capacity](https://cancerworld.net/tag/capacity/)
- [apps](https://cancerworld.net/tag/apps/)
- [earthquake](https://cancerworld.net/tag/earthquake/)
- [caregivers](https://cancerworld.net/tag/caregivers/)
- [cost](https://cancerworld.net/tag/cost/)