Cancer clinical trials recruit younger and younger patients

15 July 2019 0

Cancer clinical trial participants are significantly younger than the incident disease population. This age imbalance is particularly evident in industry-sponsored trials and raises concerns regarding the applicability of trial results. Seminal data from decades ago already demonstrated a marked underrepresentation of older patients in clinical trials: now a group of researchers from the University of Texas MD Anderson Cancer Centre analysed more than 300 randomised clinical trials (RCTs) and verified not only that the disparity persists but the gap between trial and population median ages is widening. [more]