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brca
Body weight influences breast cancer risk in women with BRCA1 and 2 mutations
Obesity may be a factor contributing to DNA damage in the breast tissue of women with BRCA1 or BRCA2 mutations. The study, published in Science Translational Medicine, February 22, suggests maintaining a healthy body weight or pharmacologically targeting oestrogen or…
Cancer and fertility preservation: it can be done… Can’t it?
“I was 26 when I was diagnosed with Hodgkin lymphoma in 2015. I knew before starting cancer treatment that it is possible to preserve fertility. But having been knocked flat by months of illness and still dazed by the diagnosis,…
Genetics of breast cancer: much more than a BRCA story
Over 450 departments and institutions worldwide have contributed to the most comprehensive study conducted so far on breast cancer risk variants whose results have been published in Nature Genetics. The fine mapping of 150 breast cancer risk regions identified nearly…