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Cancerworld Magazine > cardiotoxicity

Posts by tag

cardiotoxicity

4 posts
Second-generation BTK inhibitor shows promise as fixed-duration therapy in CLL
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Second-generation BTK inhibitor shows promise as fixed-duration therapy in CLL

  • Janet Fricker
  • 18 December 2024

Treatment with the second-generation Bruton tyrosine kinase (BTK) inhibitor acalabrutinib plus the BCL2 inhibitor venetoclax (with or without the CD20 inhibitor obinutuzumab), delivered as fixed-duration therapies, significantly improved progression free survival in comparison with standard-of-care chemotherapy in previously untreated patients…

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Common blood pressure drug could be used in AML to cut cardiotoxicity and improve response to chemotherapy
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Common blood pressure drug could be used in AML to cut cardiotoxicity and improve response to chemotherapy

  • Janet Fricker
  • 9 July 2024

Treating acute myeloid leukaemia with losartan, a commonly used blood pressure agent, achieved the dual benefits of enhancing chemotherapy efficacy and preventing cardiotoxicity in a mouse model. The study, published in Science Translational Medicine, 19 June, demonstrated both benefits were…

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New options to protect long-term health of children treated for cancer
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New options to protect long-term health of children treated for cancer

  • Victoria Forster
  • 30 May 2023

Childhood cancer is considered a success story of modern medicine, with more than 90% of children now surviving long-term in high-income countries, up from just 10% 65 years ago. Yet many children who survive their cancer go on to experience…

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ACE inhibitor protects against cardiotoxicity
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ACE inhibitor protects against cardiotoxicity

  • Janet Fricker
  • 18 June 2021

In HER2 breast cancer, concurrent use of the ACE inhibitor lisinopril with trastuzumab-anthracyclines benefits left ventricular ejection fraction (LVEF). The study, abstract 509, presented in a poster session at the ASCO meeting, June 4-8, found breast cancer patients treated with…

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