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Cancerworld Magazine > clinical trial design

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clinical trial design

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Why Patient-Reported Outcomes are Rarely Used in Trials, and How We Change That
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Why Patient-Reported Outcomes are Rarely Used in Trials, and How We Change That

  • Manuela Maria Campanelli
  • 27 May 2025

If drug developers design trials to measure how well their drug addresses the issues most important to the target patient community, we could expect to end up with better drugs. Integrating patient-reported outcomes into clinical trials is the way to…

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Combination immunotherapy with novel immune-oncology agents benefit NSCLC patients in presurgical setting
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Combination immunotherapy with novel immune-oncology agents benefit NSCLC patients in presurgical setting

  • Janet Fricker
  • 6 October 2023

Patients with resectable non-small-cell lung cancer show improved major pathological response rates with combination immune oncology agents versus single-agent immunotherapy. The NeoCOAST trial, published in Cancer Discovery, 14 September, demonstrated that combining the anti-PD-L1 monoclonal antibody durvalumab with other novel…

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    • 4 July 2025
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