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mismatch repair deficient tumours
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Neoadjuvant immunotherapy delivers unprecedented pathological response in mismatch repair deficient non-metastatic colon cancers
In patients with non-metastatic colon cancer who have mismatch repair deficient tumours, a short course of neoadjuvant immunotherapy (one cycle ipilimumab and two cycles nivolumab) was highly effective. The NICHE-2 trial, published in the New England Journal of Medicine, June…