Posts by tag
next generation sequencing
Giuseppe Curigliano: driving progress in precision cancer medicine
“Fundamentally, if you do more whole genome sequencing, you’ll discover more targetable alterations, and once you have this information you can consider whether there are any clinical trials available for your patient.” The advice comes from Giuseppe Curigliano, Head of…
Molecular tumour boards: translating data into tailored therapeutics
Developments in molecular diagnostics are allowing us to capture an extraordinarily detailed picture of the genomic and other molecular changes that characterise a given tumour specimen. But making best use of the information at our disposal is proving quite a…
Molecular diagnostics and NGS in the clinic: where are we and where do we need to go?
The development of next generation sequencing (NGS) has been a game changer for our understanding of genetics, and in turn for many aspects of biomedicine. This includes cancer, where it has led to greater understanding of the genetic changes that…
ESMO provides first recommendations on use of next-generation sequencing in metastatic cancer
Patients with metastatic non-squamous non-small-cell lung cancer (NSCLC), prostate cancers, ovarian cancers and cholangiocarcinoma should be offered next-generation sequencing (NGS) for profiling tumour samples, concludes an expert panel from the European Society for Medical Oncology (ESMO) in their review (Mosele…