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Cancerworld Magazine > NSCLC

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NSCLC

3 posts
Combination immunotherapy with novel immune-oncology agents benefit NSCLC patients in presurgical setting
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Combination immunotherapy with novel immune-oncology agents benefit NSCLC patients in presurgical setting

  • Janet Fricker
  • 6 October 2023

Patients with resectable non-small-cell lung cancer show improved major pathological response rates with combination immune oncology agents versus single-agent immunotherapy. The NeoCOAST trial, published in Cancer Discovery, 14 September, demonstrated that combining the anti-PD-L1 monoclonal antibody durvalumab with other novel…

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Stopping immunotherapy after two years does not affect NSCLC survival
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Stopping immunotherapy after two years does not affect NSCLC survival

  • Janet Fricker
  • 15 June 2023

No overall survival difference was found between patients with non-small cell lung cancer who stopped immune checkpoint inhibitors at two years and those continuing treatment indefinitely. The study, abstract 9101, presented at the ASCO 2023 Annual Meeting, held June 2–6,…

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Genetic targets identified for cancer-associated cachexia
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Genetic targets identified for cancer-associated cachexia

  • Janet Fricker
  • 5 May 2023

Distinct patterns of genes have been shown to be active in the tumours of non-small-cell lung cancer patients who go on to develop cachexia, including high activity of the protein GDF15. The study, published in Nature Medicine, April 2023 issue,…

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