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platform trials
Combination immunotherapy with novel immune-oncology agents benefit NSCLC patients in presurgical setting
Patients with resectable non-small-cell lung cancer show improved major pathological response rates with combination immune oncology agents versus single-agent immunotherapy. The NeoCOAST trial, published in Cancer Discovery, 14 September, demonstrated that combining the anti-PD-L1 monoclonal antibody durvalumab with other novel…
Trial platform informs precision treatment of childhood cancers
A stratified medicine basket study has shown the benefit of combining two targeted therapies to treat paediatric cancers with specific molecular profiles. The study, presentation number CT019, presented at the AACR (American Association for Cancer Research) Annual Meeting 2023, held…