Immuno-Oncology Research

When the first signals of modern immunotherapy began to emerge a little over a decade ago, many of us realised that oncology was about to change forever. I still remember the sense of astonishment when we saw the first durable…

Personalised neoantigen cancer vaccines (both with and without ipilimumab) elicited anticancer immune responses in nine patients with fully resected clear cell renal cell carcinoma. The investigator-initiated phase 1 trial, published in Nature, February 5 2025, observed no recurrences at a…