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Cancerworld Magazine > lynch syndrome

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lynch syndrome

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Neoadjuvant immunotherapy delivers unprecedented pathological response in mismatch repair deficient non-metastatic colon cancers
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Neoadjuvant immunotherapy delivers unprecedented pathological response in mismatch repair deficient non-metastatic colon cancers

  • Janet Fricker
  • 28 June 2024

In patients with non-metastatic colon cancer who have mismatch repair deficient tumours, a short course of neoadjuvant immunotherapy (one cycle ipilimumab and two cycles nivolumab) was highly effective. The NICHE-2 trial, published in the New England Journal of Medicine, June…

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Lynch syndrome patients show poor aspirin adherence
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Lynch syndrome patients show poor aspirin adherence

  • Janet Fricker
  • 9 February 2024

Only around one third of people with Lynch syndrome, the most common form of hereditary colorectal cancer, report taking aspirin as chemopreventive therapy. The survey, abstract 19, presented at the 2024 ASCO Gastrointestinal Cancers Symposium, held January 18–20, in San…

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Resistant starch equivalent to eating a daily banana cuts hereditary cancer risk
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Resistant starch equivalent to eating a daily banana cuts hereditary cancer risk

  • Janet Fricker
  • 5 August 2022

Consuming resistant starch (RS), also known as fermentable fibre, reduces the risk of non-colorectal cancers (non-CRCs) by nearly 50% in people with Lynch syndrome. The study, published in Cancer Prevention Research, 25 July, found that while resistant starch significantly reduced…

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