Articles
Natural killers: a new tactical unit joins the cancer immunotherapy brigade
There was a time when all that oncologists treating solid tumours needed to know about leukocytes was how to measure the damage that cytotoxic drugs inflicted on their patients’ white blood cell count and their capacity to fight off infections.…
Immunotherapy toxicities demand a joined up approach from oncologists and organ specialists
Adverse effects of cancer therapies have long been at the root of decision making for interventions in all modalities – surgery, radiotherapy and medical – and especially in the latter category of anti-cancer drugs. Most people have heard of some…
Beating cancer is complex – our messaging must be clear
A window of opportunity is opening up across Europe to reverse the ever-rising trend of new cancers and improve outcomes for patients everywhere. It’s been brought about in part by a major shift in favour of Europe taking on a…
Who wouldn’t want to cure 100% of childhood cancers?
More than eight in ten children and young adults diagnosed with cancer now survive their disease, often going on to live long and fulfilling lives. But the serious life-long damage that is inflicted by many treatments is still a bit…
Berlin pilot project brings precision care to the peripheries
A decade ago, men with metastatic prostate cancer could typically expect to live two to three years. The arrival of new hormone drugs such as abiraterone radically changed the odds, and the equation is now changing every day, as trials…
Highlights of 2020 American Society of Hematology (ASH) meeting
Like most 2020 meetings the 62nd American Society of Hematology (ASH) Annual Meeting and Exposition, held 5-8 December, was hosted virtually. Due to meticulous planning, the format did not prevent delegates attending the largest gathering of the professional haematology community…
Highlights of 2020 San Antonio Breast Cancer Symposium
In 2020, the San Antonio Breast Cancer Symposium (SABCS) co-organised in association with the American Association for Cancer Research (AACR) celebrated its 43rd year as the world’s premier annual breast oncology meeting. Like most conferences, due to the Covid-19 pandemic,…
The sunshine hormone: the many wonders of vitamin D
Vitamin D has drawn much scientific interest and media coverage in recent years, and increasingly so in 2020, when a link was found between vitamin D deficiency and Covid-19. This is a very unusual vitamin, in that it behaves both…
EMA at 25: learning more from cancer patients
Responsibility for scientific evaluation, supervision and safety monitoring of medicines was done at the national level until 1995, when EU member states agreed to coordinate that work within the European Medicines Agency (EMA). A quarter of a century on, and…
Oncolytic viruses – a new wave of therapeutic possibilities
Going back to the nineteenth century there were reports that infectious diseases seemed to provide brief periods of remission for cancer patients. One case from 1896 reported that the enlarged spleen of a woman with “myelogenous leukemia” shrank to nearly…