Cancerworld Magazine
  • About the Magazine
    • About us
    • Editorial Team
    • Events
    • Archive
    • Contacts
  • Articles
    • Policy
    • Practice Points
    • Delivery of Care
    • Biology basic
    • Medicine
    • Featured
  • Contents
    • News
    • Editorials
    • Interviews to the Expert
    • In the Hot Seat
    • Profiles
    • Obituaries
    • Voices
  • ESCO Corner
SUBSCRIBE FOR FREE
Facebook
Twitter
LinkedIn
Cancerworld Magazine
Cancerworld Magazine
  • About the Magazine
    • About us
    • Editorial Team
    • Events
    • Archive
    • Contacts
  • Articles
    • Policy
    • Practice Points
    • Delivery of Care
    • Biology basic
    • Medicine
    • Featured
  • Contents
    • News
    • Editorials
    • Interviews to the Expert
    • In the Hot Seat
    • Profiles
    • Obituaries
    • Voices
  • ESCO Corner
Cancerworld Magazine > News > Cancer caused by occupational exposure needs urgent attention
  • News

Cancer caused by occupational exposure needs urgent attention

  • 10 March 2021
  • Valéria Hartt
Cancer caused by occupational exposure needs urgent attention
Total
0
Shares
0
0
0
0
0

What is the cancer burden associated with occupational exposure? A new review shows that the question needs urgent attention, given under-reporting and current difficulties in estimating the global burden.

The review, in Molecular Oncology, highlights how millions of workers are exposed daily to crystalline silica in mineral dust, diesel engine exhaust emissions, welding fumes and wood dust.

“If employers are successful in controlling exposure in the workplace, the fraction of lung cancer attributable to occupational exposure would be reduced dramatically”, say the authors, from the International Agency for Research on Cancer (IARC) and the Institute for Risk Assessment Sciences, Utrecht University.

They review studies that use the “population attributable fractions” metric to estimate the proportion of cases that would have occurred if exposure had not been present. Together, exposure to crystalline silica, diesel engine exhaust emissions and welding fumes account for half of the occupational PAF for lung cancer, they say.

Lung cancer is the most prevalent occupational cancer, with an estimated PAF between 18 and 25% in the male population, followed by mesothelioma and bladder cancer. National studies in the United Kingdom, France and Canada suggest that nasopharyngeal tumours and non-melanoma skin cancers (NMSC) are also among the top five occupational cancers.

The publication reports the association between nasopharyngeal tumours and exposure to wood dust and formaldehyde, as well as non-melanoma skin cancers (NMSCs) in workers exposed to solar radiation and substances such as coal tars and pitches, mineral oils and arsenic.

It highlights possible variations due to differences in the manufacturing and composition of different materials. The composition of organic dust can vary dramatically when working with different moisture levels, and exposure to substances generated by combustion can also vary according to where the emission takes place (surface or underground mining, for example) and type and age of engine.

Another warning is that many occupational exposures have a larger effect on smokers. An analysis (the SYNERGY Project) of the interaction between smoking and exposure to occupational lung carcinogens showed the effect of both exposures exceeded the sum of each individually.

According to the World Health Organization (WHO), there were 472,124 deaths attributable to occupational cancer in 2018, equivalent to 53% of the total deaths due to work-related chronic diseases. Nevertheless, the numbers could be a major underestimate.
“The prevalence of process-generated substances in the majority of countries, including low-and middle-income countries, is largely unknown, because few studies have been conducted locally”, say the authors, Ann Olsson, epidemiologist at IARC and Hans Kromhout from Utrecht University.

Limited available data means that PAFs, criteria for defining prevalence of occupational cancers and levels of exposure are not easily comparable in studies. Methodological differences also call into question the sensitivity of occupational exposure estimates, say the authors.

Total
0
Shares
Share 0
Tweet 0
Share 0
Share 0
Share 0
Related Topics
  • Lung cancer
  • occupational cancer
Valéria Hartt

Valéria Hartt is a journalist focused on cancer coverage, master’s in science by Oswaldo Cruz Foundation (FIOCRUZ), the most prominent institution of science and technology in health in Latin America, founder and director of Onconews, a leading media about Oncology in Portuguese language.

Previous Article
  • News

European vision for universal access to oncology precision medicine biomarker tests

  • 8 March 2021
  • Janet Fricker
View Post
Next Article
  • Articles
  • Delivery of Care

Our pathways: advocates provide roadmaps for patients, clinicians and managers

  • 11 March 2021
  • Simon Crompton
View Post
You May Also Like
View Post
  • News

Personalised neoantigen vaccine for kidney cancer shows promise in phase 1 study

  • Yeva Margaryan
  • 8 May 2025
View Post
  • News
  • Senza categoria

What Caught Our Eye in April: Oncology’s Top Moments

  • Yeva Margaryan
  • 7 May 2025
View Post
  • News

CancerWorld #102 (April 2025)

  • Yeva Margaryan
  • 22 April 2025
View Post
  • News
  • Senza categoria

What Caught Our Eye in March: Oncology’s Top Moments

  • Yeva Margaryan
  • 8 April 2025
View Post
  • News

Ovarian cancer: mechanism conferring resistance to immunotherapy revealed

  • Janet Fricker
  • 21 March 2025
View Post
  • News

Muscular strength and cardiorespiratory fitness improve survival in cancer patients

  • Janet Fricker
  • 20 March 2025
View Post
  • News

CancerWorld #101 (February 2025): The Must-Read Oncology Issue Returns to Print with Exclusive Interviews and Breakthroughs

  • Yeva Margaryan
  • 18 March 2025
View Post
  • News

Low-dose aspirin reduces colorectal cancer recurrence in patients with PI3K alterations

  • Janet Fricker
  • 6 March 2025
search
CancerWorld #101 Download CancerWorld #101 Download CancerWorld #101 Download or search in Cancerworld archive
Newsletter

Subscribe free to
Cancerworld!

We'll keep you informed of the latest features and news with a fortnightly email

Subscribe now
Latest News
  • Personalised neoantigen vaccine for kidney cancer shows promise in phase 1 study
    • 8 May 2025
  • What Caught Our Eye in April: Oncology’s Top Moments
    • 7 May 2025
  • CancerWorld #102 (April 2025)
    • 22 April 2025
  • What Caught Our Eye in March: Oncology’s Top Moments
    • 8 April 2025
  • Ovarian cancer: mechanism conferring resistance to immunotherapy revealed
    • 21 March 2025
Article
  • Miriam Merad and the 2025 Sjöberg Prize: A Celebration of Innovation in Cancer Immunotherapy
    • 6 May 2025
  • Istanbul, Ankara take action on HPV vaccination, as government delays promised national programme
    • 1 April 2025
  • Could this dual approach be the frontier that finally gets immunotherapy to work for MSS colorectal cancer?
    • 31 March 2025
Social

Would you follow us ?

Contents
  • Miriam Merad and the 2025 Sjöberg Prize: A Celebration of Innovation in Cancer Immunotherapy
    • 6 May 2025
  • “I really care about people.” – Philip Kantoff, A Life in Science and Medicine
    • 5 May 2025
  • What If the World’s Leading Prostate Cancer Epidemiologist Opened a Restaurant? A Conversation with Lorelei Mucci- A Harvard Scientist, A Mother, A Leader
    • 23 April 2025
MENU
  • About the Magazine
    • About us
    • Editorial Team
    • Events
    • Archive
    • Contacts
  • Articles
    • Policy
    • Practice Points
    • Delivery of Care
    • Biology basic
    • Medicine
    • Featured
  • Contents
    • News
    • Editorials
    • Interviews to the Expert
    • In the Hot Seat
    • Profiles
    • Obituaries
    • Voices
  • ESCO Corner
Cancerworld Magazine
  • About us
  • Articles
  • Media Corner
  • Privacy Policy
  • Cookie Policy

Cancerworld is published by OncoDaily (P53 Inc.) | Mailing Address: 867 Boylston st, 5th floor, Ste 1094 Boston, MA 02116, United States | [email protected]

Archivio Cancerworld

Input your search keywords and press Enter.