News
Anti-oestrogen provides novel strategy to boost checkpoint inhibitors
Adding anti-oestrogen therapy improves response to combined chemotherapy and immune checkpoint inhibition in tumours that do not express oestrogen receptors. The Japanese study, published in British Journal of Cancer, provides…
Anticancer benefits from Mediterranean ‘lifestyle’ can be transferred to non-Mediterranean population
High adherence to a ‘Mediterranean lifestyle’ is associated with lower cancer mortality in a dose-responsive manner. The study, published in Mayo Clinic Proceedings (16 August), showed that UK adults who…
Europe’s patient advocates skill up to better influence cancer care and research agendas
Patient advocates for a wide range of cancer communities across Europe spent four days at the start of July honing the skills they need to influence the policy, research and…
Transcriptional signature provides clue to CAR T cell longevity
A transcriptional signature of 21 genes has been found to occur across patients with paediatric B-cell acute lymphoblastic leukaemia who have durable responses and long-lived CAR T cells. The UK…
Cardiorespiratory fitness reduces risk of developing and dying from cancer
Higher levels of cardiorespiratory fitness may reduce the incidence and mortality of specific cancers in men. The Swedish male cohort study, published online in JAMA Open Network, June 29, found…
Four-protein biomarker test helps personalise lung cancer screening
Integrating a panel of four circulating protein biomarkers with a lung cancer risk model identified individuals at high risk of developing fatal lung cancer. The study published in Journal of…
Immune resilience: a clue to why some people live longer, have fewer infections, and get less recurrent cancer
Kidney transplant patients with high immune resilience, defined as the capacity to preserve/restore immunocompetence and control inflammation during inflammatory stress, are less likely to develop recurrent skin cancer compared to…
Multi-cancer early detection blood test speeds up cancer diagnosis
showed a positive predictive accuracy of 75% and negative predictive accuracy of 98% in a population referred for diagnostic follow-up after presenting to primary care…
Stopping immunotherapy after two years does not affect NSCLC survival
No overall survival difference was found between patients with non-small cell lung cancer who stopped immune checkpoint inhibitors at two years and those continuing treatment indefinitely. The study, abstract 9101,…
Adding a CDK4/6 inhibitor to endocrine therapy improves outcomes in HR+ HER2– early-stage breast cancer
Adding the CDK4/6 inhibitor ribociclib to standard-of-care adjuvant endocrine therapy for treatment of hormone receptor-positive HER2-negative early-stage breast cancer reduced risk of recurrence by 25%. The phase III NATALEE study,…