Posts by tag
breast cancer
Updated MINDACT results reveal chemotherapy benefit in some breast cancers varies by age
Updated results of the MINDACT trial confirm that women with early-stage breast cancer, who were assessed to be at high clinical but low genomic risk for recurrence, and did not receive chemotherapy, continue to have excellent distant metastasis free survival…
Bridging the Age Gap in Breast Cancer: A treatment selection tool for the over-70s
Q. Surgery tends to be a bigger issue for older people, and physicians need reliable guidance on who is likely to benefit and who could be harmed. You looked at selection practices and outcomes at 56 breast units across the…
Oncology providers urged to offer healthy life style advice to breast cancer survivors
Breast cancer survivors commonly experience treatment-related factors, such as fatigue, depression and discomfort, presenting barriers to the adoption of healthy life styles. The US questionnaire study, published in the Journal of the Academy of Nutrition and Dietetics (1 February 2021),…
Studies provide clarity on breast cancer genes for genetic panels
Two large case control studies have defined eight genes considered useful to include on genetic panels for predicting risk of breast cancer. The two studies, one by The Breast Cancer Association Consortium (BCAC), led by Doug Easton in Cambridge, and…
Therapy targeting androgen receptors opens new chapter for hormone driven breast cancers
Androgen receptor activation exerts potent antitumour activity in oestrogen receptor positive breast cancer. The international study, published in Nature Medicine (18th January), has important therapeutic implications for women with metastatic breast cancers that are oestrogen receptor positive, including those who…
20-year WHI follow-up study finds oestrogen selectively protects against breast cancer in women who have undergone hysterectomy
A 20-year follow-up of the two Women’s Health Initiative (WHI) hormone replacement studies found that, among postmenopausal women with prior hysterectomy, use of oestrogen in comparison to placebo was associated with lower breast cancer incidence and mortality, while among those…
Night-shift work and breast cancer risk: potential biological mechanism identified
Is night-shift work a risk factor for breast cancer? Experimental research just published in Nature Communications gives the molecular basis for asserting that it may well be. Researchers at Paris-Saclay University, with colleagues from Inserm and Inrae, studied the association…
The ABC Global Alliance launch a Global campaign to raise awareness about advanced breast cancer
There are over two million new cases of breast cancer a year in the world and 0.6 million deaths. About a third of all early breast cancer cases will become metastatic even with the best care, and the average overall…
Parity and breast cancer risk are not so strictly linked
The reduction in birth rate has been blamed in the past for the increase in breast cancer in young women, but now a study just published in JAMA Network Open (JAMA Netw Open. 2020;3(3):e200929. doi:10.1001/jamanetworkopen.2020.0929) offers evidence refuting this hypothesis:…
In memory of Aron Goldhirsch, challenging oncologist with a vision
Prof. Aron Goldhirsch, an outstanding representative of italian Medical Oncology, awarded and recognized internationally, passed away on February 26. Since 2019, he was Medical Consultant at the Breast Cancer Center in Multimedica (Milan, Italy). For many years he held the…