Posts by tag
Colorectal cancer
What Caught Our Eye in April: Oncology’s Top Moments
April 2025 marked a significant month in oncology, with notable advancements in cancer treatment and research. Here’s a summary of the most compelling studies and recent breakthroughs that caught our eye this month. Popular CT scans could account for 5%…
Could this dual approach be the frontier that finally gets immunotherapy to work for MSS colorectal cancer?
It is often said in medicine that the only true constant in facing life-threatening diseases is change. Nowhere is this more evident than in oncology, where advances in chemotherapy, targeted therapies, immunotherapies, and other novel agents continue to spark hope.…
Low-dose aspirin reduces colorectal cancer recurrence in patients with PI3K alterations
Taking adjuvant low-dose aspirin daily for three years reduced recurrence of colorectal cancer by 55% in patients with somatic alterations in PI3K signalling compared to those taking placebo. The results of the ALASCCA study, presented at the 2025 ASCO Gastrointestinal…
Young-onset digestive cancers: this is how we improve the quality of care
“I had very severe symptoms. I had jaundice, I had itching – symptoms that could definitely indicate something related to the liver, or quite severe disease – but because of my age I was repeatedly just shoved away.” (Gabriel, eventually…
Aspirin prevents colorectal cancer best in those with least healthy lifestyles
Regular aspirin may help lower risk of colorectal cancer most effectively in people who have greater lifestyle-related risk factors for the disease. The study, published in JAMA Oncology on 1 August, found that, to prevent one case of colorectal cancer…
Study indicates people with type 2 diabetes need increased colorectal cancer screening
People with type 2 diabetes have a 47% increased risk of developing colorectal cancer (CRC) in comparison to people without diabetes. The cohort study, published in Jama Network Open, 15 November, suggests that regular CRC screening should become integral to…
Gut microbiome offers new avenue for detecting colorectal cancer
Significant variations in the gut microbiome can be identified between people who develop pre-cancerous colonic lesions and those who do not. The Dutch study, abstract OP118, presented at United European Gastroenterology (UEG) Week 2023, held in Copenhagen, October 14–17, showed…
Statin use lowers risk of colorectal cancer in inflammatory bowel disease
Statin use was associated with a lower risk of colorectal cancer, colorectal cancer related mortality, and all-cause mortality in a patient population with inflammatory bowel disease. The Swedish study, published online in eClinicalMedicine, 1 September, found benefits depended on duration…
Cancer could overtake cardiovascular disease as leading cause of death in type 2 diabetes
Mortality from cancer has increased among older people with type 2 diabetes. The UK cohort study, published in Diabetologica, 24 January, found people with type 2 diabetes were at particular risk of mortality from colorectal, pancreatic, liver and endometrial cancers.…
Repurposed drug combination reduces risk of recurrence following surgery for colorectal cancer
Pharmacological suppression of adrenergic and inflammatory signalling using readily available drugs to lower blood pressure and reduce anxiety decreased the risk of post-surgical colorectal cancer (CRC) recurrence. The pilot COMPIT study, published in the European Journal of Surgical Oncology, 6…