Articles
Cancer drugs for Africa… from Africa?
More than two years ago, Cipla Quality Chemical Industries, a pharmaceutical manufacturing company in Kampala, Uganda, announced that it would start producing cancer drugs. In a deal agreed in 2021…
Cracking RAS: It took over 30 years to hit this ubiquitous oncogene – was it worth the wait?
RAS oncogenes and their proteins have central roles in almost all cancers, including leukaemias, multiple myelomas, skin cancers and many solid tumours, making the RAS protein family an ideal cancer…
The CRISPR revolution: it’s transforming cancer research, can it do the same for treatment?
CRISPR is a revolutionary gene-editing tool that allows scientists to cut DNA with extraordinary precision and make changes to the genome. The technology was a gift to cancer researchers, whose…
New options to protect long-term health of children treated for cancer
Childhood cancer is considered a success story of modern medicine, with more than 90% of children now surviving long-term in high-income countries, up from just 10% 65 years ago. Yet…
AI-generated radiotherapy planning could boost access to high-quality treatment across the globe
Can artificial intelligence help design radiotherapy treatment plans, reducing time and cost while matching the quality of skilled professionals? That is the question that a new multi-centre and multi-arm ARCHERY…
Precision cancer nursing: using the personalised medicine paradigm to improve patient care
Precision medicine is transforming the way we treat cancer. Oncology is evolving from treating purely on the basis of a broad indication to a tailored approach that is based on…
CAR T cells v chemo for childhood leukaemia: are we ready for the next step?
Chimeric antigen receptor (CAR) T cells, genetically engineered immune cells targeted to attack cancers, are one of the most exciting breakthrough cancer treatments in oncology today. After decades of incremental…
How do I respond? Advice for friends and family on supporting someone through cancer
A few days after being diagnosed with cancer, at only 32 years of age, Katarzyna Chmielewska-Wojciechowska met a friend who asked, in passing, how she was doing. She told him.…
Molecular tumour boards: translating data into tailored therapeutics
Developments in molecular diagnostics are allowing us to capture an extraordinarily detailed picture of the genomic and other molecular changes that characterise a given tumour specimen. But making best use…
Unpaid women carers: recognising their contribution and their needs in Latin America
Researchers and public policies have historically overlooked the challenges of informal caregiving for cancer patients in Latin America. Now, public health experts are working to profile this neglected group, evaluate…