News
US study suggests colorectal cancer screening should start at age 45
Screening women below the age of 50 for colorectal cancer (CRC) can significantly reduce their risk in comparison to those who have no endoscopic screening or who initiate testing at age 50. The study in JAMA Oncology, published online 5…
Multicomponent prevention strategy reduces risk of cancer
The combination of high-dose vitamin D, omega-3 and a simple home strength exercise programme (SHEP) reduced the risk of healthy adults aged 70 or older developing cancer by nearly two-thirds. The study, published in Frontiers in Aging, 25 April, showed that…
Lumpectomy as effective as mastectomy in young breast cancer patients
Women under 40 with non-metastatic breast cancer experience similar survival regardless of whether they are treated with mastectomy or lumpectomy. The abstract presented at the American Society of Breast Surgeons annual meeting, held in Las Vegas, April 2022, showed that…
Multi organ chip could facilitate personalised cancer therapy
A ‘plug-and-play’ multi-organ chip, the size of a microscope slide, could be customised for individual cancer patients to determine personalised therapy. The study, published in Nature Biomedical Engineering, reports for the first time the achievement of connecting a range of…
100,000 Genomes Project pinpoints new cancer genetic culprits
DNA analysis of thousands of tumours in the 100,000 Genomes project has uncovered a ‘treasure trove’ of 58 new mutational signatures causing cancer. The study, published in Science, 21 April, showed that while there are common signatures for cancers arising…
IL-6 provides missing link between exercise and colon cancer protection
Interleukin-6 (IL-6) molecules released into the systemic circulation during exercise elicit biological effects limiting colon cancer cell proliferation. The UK study, published in International Journal of Cancer, 7 April, provides a potential mechanism of action explaining how regular physical activity…
CAR T-cell therapy shows efficacy in solid tumours
A CAR T-cell therapy first-in-human study demonstrated early signs of efficacy for patients with a range of solid tumours, including testicular and ovarian cancers. The study, presented at the American Academy of Cancer Research (AACR) 2022 Annual Meeting (8-13 April…
No link between brain tumours and ‘usual’ use of mobile phones
‘Usual’ use of mobile phones does not increase the incidence of brain tumours. The prospective study, published in the Journal of the National Cancer Institute, 30 March 2022, found no statistically significant associations between ‘ever’ users and ‘never’ users of…
Radiologists urged to report breast arterial calcification for CVD prevention
Routine mammograms could be used to provide additional information about women’s risk of cardiovascular disease (CVD). The study, published in ‘Circulation: Cardiovascular imaging’, March 15, found women with breast arterial calcification had a 51% higher risk of heart attacks and…
Colorectal cancer linked to lifetime of excess weight
Cumulative lifetime exposure to excess weight accounts for a larger share of Colorectal cancer (CRC) risk than previously appreciated. The German study, published in JAMA Oncology, 17 March, demonstrates the importance of characterizing long-term exposure to weight gain and making…