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Cancerworld Magazine > News

News

262 posts
Ultra-sensitive immunoassay detects key protein produced by cancer cells
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Ultra-sensitive immunoassay detects key protein produced by cancer cells

  • Janet Fricker
  • 17 November 2023

A blood test detecting a key protein produced by cancer cells is showing promise as an early indicator of cancer. The study, published in Cancer Discovery, September 12, suggests that the ultra-sensitive assay for LINE-1-ORF1p  offers potential as an effective…

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Gut microbiome offers new avenue for detecting colorectal cancer
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Gut microbiome offers new avenue for detecting colorectal cancer

  • Janet Fricker
  • 2 November 2023

Significant variations in the gut microbiome can be identified between people who develop pre-cancerous colonic lesions and those who do not. The Dutch study, abstract OP118, presented at United European Gastroenterology (UEG) Week 2023, held in Copenhagen, October 14–17, showed…

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Machine learning improves accuracy of survival prediction
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Machine learning improves accuracy of survival prediction

  • Janet Fricker
  • 2 November 2023

An artificial intelligence prototype has been developed to estimate the survival of newly diagnosed cancer patients with breast, thyroid, and pancreatic cancers. The study, abstract 4160, presented at the American College of Surgeons (ACS) Clinical Congress 2023, October 22–25, Boston,…

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Walkable neighbourhoods lower risk of obesity related cancers
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Walkable neighbourhoods lower risk of obesity related cancers

  • Janet Fricker
  • 20 October 2023

Women living in US neighbourhoods with higher levels of ‘walkability’ have lower risks of obesity related cancers, including postmenopausal breast, endometrial, ovarian, and multiple myeloma. The prospective study, published in Environmental Health Perspectives, 10 October, found women living in neighbourhoods…

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Dichloroacetate shows promise in treating cancer-related fatigue
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Dichloroacetate shows promise in treating cancer-related fatigue

  • Janet Fricker
  • 19 October 2023

Dichloroacetate, a drug targeting the metabolism, helped alleviate cancer related fatigue in mouse models of melanoma and colon cancer, reports a study published in the American Journal of Physiology Endocrinology and Metabolism, 2 October. “This study tackles the long-understudied conundrum of…

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Combination immunotherapy with novel immune-oncology agents benefit NSCLC patients in presurgical setting
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Combination immunotherapy with novel immune-oncology agents benefit NSCLC patients in presurgical setting

  • Janet Fricker
  • 6 October 2023

Patients with resectable non-small-cell lung cancer show improved major pathological response rates with combination immune oncology agents versus single-agent immunotherapy. The NeoCOAST trial, published in Cancer Discovery, 14 September, demonstrated that combining the anti-PD-L1 monoclonal antibody durvalumab with other novel…

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Trial defines breast cancer population who can omit sentinel node biopsy
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Trial defines breast cancer population who can omit sentinel node biopsy

  • Janet Fricker
  • 6 October 2023

Breast cancer patients with no axillary lymph node involvement apparent on ultrasound scans, and with tumours less than 2cm, had similar outcomes regardless of whether they underwent sentinel lymph node biopsy or no axillary surgery. The results of the Italian…

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Statin use lowers risk of colorectal cancer in inflammatory bowel disease
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Statin use lowers risk of colorectal cancer in inflammatory bowel disease

  • Janet Fricker
  • 22 September 2023

Statin use was associated with a lower risk of colorectal cancer, colorectal cancer related mortality, and all-cause mortality in a patient population with inflammatory bowel disease. The Swedish study, published online in eClinicalMedicine, 1 September, found benefits depended on duration…

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New drug breaks through fibrotic tissue in pancreatic cancer
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New drug breaks through fibrotic tissue in pancreatic cancer

  • Janet Fricker
  • 21 September 2023

A drug targeting scar-like ‘fibrotic’ tissue within tumours shows promise for treating pancreatic ductal adenocarcinoma (PDAC). In the study, reported online in Nature Cancer, 28 August, Australian investigators showed in mouse and human models of PDAC that, when the drug…

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Anti-oestrogen provides novel strategy to boost checkpoint inhibitors
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Anti-oestrogen provides novel strategy to boost checkpoint inhibitors

  • Janet Fricker
  • 8 September 2023

Adding anti-oestrogen therapy improves response to combined chemotherapy and immune checkpoint inhibition in tumours that do not express oestrogen receptors. The Japanese study, published in British Journal of Cancer, provides a new rationale for introducing therapies blocking oestrogen signalling to…

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