Posts by tag
Tumor Microenvironment
Rethinking Immunotherapy for Pancreatic Cancer: A Universal Approach
Chimeric antigen receptor natural killer T (CAR-NKT) cell therapy, a novel form of immunotherapy, is emerging as a promising ‘off-the-shelf’ treatment for patients with pancreatic cancer. In a study published in PNAS, November 21, 2025, U.S. investigators report that CAR-NKT cells…
Microbiota-Derived Bile Acids as Androgen Receptor Antagonists Enhance Anti-Tumour Immunity
The gut microbiota can transform cholesterol-derived bile acids into metabolites capable of blocking androgen receptors and strengthening anti-cancer immunity. The study, published in Cell, April 15, demonstrates how one of the microbiota-derived secondary bile acids is capable of suppressing tumour…
Miriam Merad and the 2025 Sjöberg Prize: A Celebration of Innovation in Cancer Immunotherapy
Every year, the Sjöberg Prize, established by the Royal Swedish Academy of Sciences, honors researchers whose scientific discoveries in oncology are reshaping the understanding and treatment of cancer. The award stands alongside the most prestigious accolades in science, not only…