Posts by author
Janet Fricker
Could Radiotherapy Offer Unexpected Protection Against Alzheimer’s Disease?
Women who survive breast cancer may face a surprising advantage: a lower risk of developing Alzheimer’s disease than their peers without cancer. The cohort study, published in JAMA Network Open, 20 June, found that breast cancer survivors had an 8%…
Antidepressants Show Potential to Fight Cancer
Selective serotonin reuptake inhibitors (SSRIs) enhanced the ability of T cells to fight cancer and suppressed tumour growth across a range of cancer types in both mouse and human tumour models. The study, published in Cell, May 20, further showed…
BRCA1/BRCA2 Mutations Carriers at Greater Risk for Anaplastic Large Cell Lymphoma Associated with Breast Implants
Breast cancer survivors who carry BRCA1 or BRCA2 mutations and received textured implants are 16 times more likely to develop breast implant-associated anaplastic large cell lymphoma (BIA-ALCL) than those who have implants but do not carry these mutations. The study,…
How a Simple Photo Can Help Predict Survival in Cancer Patients: The FaceAge AI
A deep learning model using biological age estimations from photographs improved physicians’ survival predictions in patients with incurable cancer receiving palliative care. The study, published in Lancet Digital Health, found that the faces of cancer patients averaged five years older…
Cannabis Use is Linked to Increased Mortality in Colon Cancer Patients
Colon cancer patients with a documented history of high cannabis use prior to diagnosis showed dramatic increases in mortality. The study, published in the Annals of Epidemiology on April 28, found that cannabis users were nearly 25 times more likely…
How a Brain-Destroying Protein Became Cancer’s Ally: Alpha-Synuclein Emerges as a New Target in Melanoma
The alpha-synuclein, a protein long associated with Parkinson’s disease may hold the key to melanoma proliferation. The study, published in Science Advances, on 9 April, suggests that while excess alpha-synuclein results in cell death in neurons, conversely, it enables uncontrolled…
Microbiota-Derived Bile Acids as Androgen Receptor Antagonists Enhance Anti-Tumour Immunity
The gut microbiota can transform cholesterol-derived bile acids into metabolites capable of blocking androgen receptors and strengthening anti-cancer immunity. The study, published in Cell, April 15, demonstrates how one of the microbiota-derived secondary bile acids is capable of suppressing tumour…
Strategies Needed to Prioritise Screening in Survivors of Childhood Cancer
Survivors of childhood cancer experience accelerated onset of ageing-related diseases, regardless of prior radiation exposure. The simulation modelling study, published in JAMA Oncology, online March 20, found that chronic health conditions developed 10 to 20 years earlier than expected and…
Common Diabetes Medication Could Protect Heart Health During Cancer Treatment
Sodium-glucose cotransporter 2 (SGLT2) inhibitors, a common type of diabetes medication, may protect the heart during and after cancer treatment. The systematic review and meta-analysis, published in European Journal of Preventive Cardiology on 6 March, shows that SGLT2 inhibitors halve…
Personalised neoantigen vaccine for kidney cancer shows promise in phase 1 study
Personalised neoantigen cancer vaccines (both with and without ipilimumab) elicited anticancer immune responses in nine patients with fully resected clear cell renal cell carcinoma. The investigator-initiated phase 1 trial, published in Nature, February 5 2025, observed no recurrences at a…