News
Colorectal cancer linked to lifetime of excess weight
Cumulative lifetime exposure to excess weight accounts for a larger share of Colorectal cancer (CRC) risk than previously appreciated. The German study, published in JAMA Oncology, 17 March, demonstrates the importance of characterizing long-term exposure to weight gain and making…
European Cancer Community urged to sign-up to help Ukrainian patients
The European Cancer Organisation (ECO) and American Society of Clinical Oncology (ASCO) have launched a network to provide an infrastructure to support Ukrainian cancer patients. The Special Network on the Impact of the War in the Ukraine on Cancer, launched…
No reason to delay cancer immunotherapy following antibiotic use
Exposure to antibiotics prior to anti-PD-1 antibody treatment had no effect on melanoma outcomes. The French study, reported in the Journal of the National Cancer Institute (published March 7, 2022), found using antibiotics in a large cohort of advanced melanoma…
Harmful bacteria play greater role in predicting outcomes of immune checkpoint blockade in melanoma
Harmful gut bacteria may play a greater role than beneficial bacteria in determining efficacy of immune checkpoint blockade in melanoma patients. The study, published in Nature Medicine (28 February), found microbial signatures containing Lachnospiraceae species were connected to favourable anti-programmed…
Starting age for MRI breast screening defined for three genetic mutations
Annual magnetic resonance imaging (MRI) starting from age 30 to 35 years followed by combined annual MRI and mammography from age 40 may reduce breast cancer mortality by over 50% for women with ATM, CHEK2, and PALB2 breast cancer genetic…
Aromatase inhibitors better than tamoxifen in premenopausal breast cancer
Giving aromatase inhibitors (AIs) instead of tamoxifen to premenopausal women with oestrogen receptor positive breast cancer, who have undergone ovarian suppression, significantly reduces risk of recurrence. The study, published in The Lancet Oncology (3 February), found that breast cancer recurrence…
After Covid: AACR call to action to improve cancer care
The American Association for Cancer Research (AACR) has issued ‘a call to action’ to build on lessons learnt from Covid-19 to modernize cancer patient care. The ‘ACCR Report on the Impact of Covid-19 on Cancer Research and Patient Care’, published…
Study suggests prehabilitation should become standard of care in oesophageal cancer
Enrolling oesophageal cancer patients in prehabilitation exercise programmes can boost tumour regression during chemotherapy. The small study, published in British Journal of Sports Medicine (online 1 February, 2022), demonstrated improved pathological, radiological and immunological responses to chemotherapy for those in the…
Citizen science: Do your bit for cancer research by playing a game
Calling all gamers ‒ you can do your bit for advancing cancer research by playing a video game. While this may sound like the ultimate excuse, Spanish investigators really have just launched a smartphone game ‒ the GENIGMA challenge ‒…
Study unveils how obesity raises cancer risk
Obesity-dependent changes in lipid handling in cells may explain why overweight people are more prone to developing cancer than those of normal weights. The study, published in Nature Communications (14 January 2022), identifies higher levels of palmitic acid as the…