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AACR: cancer vaccine combination shows clinical activity in advanced solid tumors
According to an industry-funded, preliminary clinical trial presented at the AACR Virtual Annual Meeting currently underway, a personalized cancer vaccine in combination with the PD-L1 inhibitor atezolizumab appears to be well tolerated and to show modest clinical benefit in patients…
Cancer prevention through physical activity and diet: an updated guideline from the U.S.
According to the latest update of the American Cancer Society (ACS) guideline, four main pillars are needed to keep cancer away using diet and exercise. Here they are: achieve and maintain a healthy body weight throughout life, be physically active,…
The burnout epidemic in oncology, highlights form ASCO 2020
“Burnout is universal and no one is immune. We are all in this together and together we can come up with solutions”. Tara Sanft, Associate Professor of Medicine at the Yale School of Medicine, New Haven (U.S.A.), came to these…
Cancer drugs, costs and clinical benefits are not aligned
According to an international study just published in Lancet Oncology, the cost of new cancer drugs is not associated to the clinical value of the therapy: “In the USA and European countries, prices of cancer drugs should be better aligned…
A global registry for children with cancer and COVID-19
While a deeper knowledge about the impact of COVID-19 disease on cancer patients is essential, sharing information is likewise important. For these purposes, a number of registries, which gather different data including patients’ outcomes or treatment, are being set up around…
Hormone therapy for prostate cancer may shield from COVID-19
[caption id="attachment_9949" align="alignright" width="324"] Abnormal Lipid Metabolism in Prostate Cancer (Source: National Cancer Institute Purdue University Center for Cancer Research. Image by Ji-Xin Cheng)[/caption] Prostate cancer patients treated with androgen-deprivation therapies (ADTs) seem to have a lower risk of SARS-CoV-2…
The misuse of “noninferiority” in presenting trials is often misleading
When researchers have the opportunity to present their trials at medical meetings, they tend to use not-negative conclusions to discuss formally negative results. A research published in JAMA Oncology by a group of Italian oncologists from the University of Turin…
Artificial intelligence might help improve the classification of colorectal polyps
Deep neural networks are as good as practicing pathologists in classifying colorectal polyps, according to an experiment by a computer science and clinical research team led by Saeed Hassanpour, from the Dartmouth Cancer Center in Lebanon (New Hampshire). The team…
Gender equality in cancer research is still far away
Despite a positive trend toward equality in the past 3 decades, a substantial gendered difference is now persisting in oncology publications, favouring male first and last authors. “The academic medicine pipeline poses a significant challenge for workforce development, with disproportionately…
European heavy weights share their wisdom on how to deal with COVID-19 and cancer
The consortium Cancer Core Europe has collected, elaborated and shared the steps top experts have taken, while scientific evidence is still in the making Several top cancer centres from all around Europe have just published the results of their in-depth…