cancer research

A mouse model of lung cancer has uncovered a potential new therapeutic strategy for treating cancer cachexia. The study, published in Science on 2 July, found that Lkb1-mutant lung tumours—a common subtype of lung cancer—can communicate directly with the brain…

Large meta-analysis suggests patient-reported outcomes complement traditional clinical assessment. Despite advances in imaging, molecular profiling, and biomarkers, accurately estimating how long a patient with cancer is likely to survive remains challenging. Now, a large analysis involving data from more than…

We often describe progress in oncology through the language of discovery. Scientific breakthroughs. Technological innovation. Deeper biological insight. These advances have transformed medicine, helping millions of people live longer and better than ever before. Yet alongside every scientific breakthrough, a…

Daraxonrasib nearly doubled median survival in previously treated metastatic pancreatic cancer. For Dr Eileen O’Reilly, the result is not simply a remarkable curve on a conference screen, but the beginning of a new way to think about a disease long…

Pancreatic ductal adenocarcinoma remains one of the most difficult cancers to treat, with limited progress in drug development over the past decade. At the 2026 ASCO Annual Meeting, the Phase 3 RASolute 302 trial delivered results that stood out against…

How Professor Nagi El Saghir Changed the Language of Cancer in the Middle East and Helped Redefine Global Oncology The airport in Beirut looked very different in 1971. Families walked all the way to the aircraft. Parents accompanied their children…

Five trials, five cancers, and what the ASCO 2026 plenary really promised patients ASCO 2026’s plenary delivered five real advances across five cancers, and a standing ovation that pulled a hall full of oncologists to their feet. The harder question…

CAM use linked to higher mortality in breast cancer patients A cohort study of women with breast cancer has shown that use of complementary and alternative medicine (CAM) in association with traditional therapies was associated with higher mortality compared with…

The 2026 Pezcoller Foundation–AACR International Award for Extraordinary Achievement in Cancer Research has recognised two scientists whose discoveries reshaped one of oncology’s greatest ambitions: preventing cancer before it begins. On 9 May, at the Teatro Sociale in Trento, Italy, Dr…

Metastatic pancreatic cancer remains one of the most treatment-refractory solid tumours in oncology. Despite multiple incremental refinements over the past decade, first-line therapy continues to rely on cytotoxic chemotherapy, most commonly FOLFIRINOX or gemcitabine plus nab-paclitaxel, with limited change in…