Posts by tag
melanoma
Rise in initiation of immunotherapy at the end of life
Immunotherapy is increasingly being initiated in the month prior to death in patients with stage IV non-small-cell lung cancer, melanoma, and renal cell carcinoma. The US study, published in JAMA…
Dichloroacetate shows promise in treating cancer-related fatigue
Dichloroacetate, a drug targeting the metabolism, helped alleviate cancer related fatigue in mouse models of melanoma and colon cancer, reports a study published in the American Journal of Physiology Endocrinology and…
Personalised RNA vaccine combined with immune checkpoint inhibitor shows efficacy in melanoma
In advanced melanoma, adding a personalised mRNA-based vaccine to the immune checkpoint inhibitor pembrolizumab improved recurrence-free survival compared with pembrolizumab alone. The KEYNOTE-942 study (presentation number CT001), presented at the…
Harmful bacteria play greater role in predicting outcomes of immune checkpoint blockade in melanoma
Harmful gut bacteria may play a greater role than beneficial bacteria in determining efficacy of immune checkpoint blockade in melanoma patients. The study, published in Nature Medicine (28 February), found…
High-fibre diets associated with improved melanoma immunotherapy response
Melanoma patients eating greater quantities of fibre-rich foods at the start of checkpoint inhibitor immunotherapy survive longer than patients with insufficient dietary fibre intake. The observational study, published in Science…
Antihistamines could improve efficacy of checkpoint inhibitors
Over-the-counter antihistamines appear to improve outcomes for cancer patients treated with checkpoint inhibitors. The study, reported in Cancer Cell (published online 24 November), found that melanoma and lung cancer patients…
Artificial intelligence for skin cancer diagnosis, from science-fiction to reality
Artificial intelligence (AI) is a hot topic in many sciences, including medicine. A machine capable of making a medical diagnosis in full autonomy is fascinating and highly attractive. “Many years…