Posts by tag
antibody drug conjugate
It’s no longer taboo to suggest that some metastatic breast cancers may be curable
It’s long been clear that, in most patients with metastatic HER-positive breast cancer, adding effective HER2 blockade to cytotoxics can result in very prolonged responses. Janet Fricker reports on the prospective trials building evidence on whether – and in whom…
Antibody-drug conjugate proves effective against active brain metastases
The antibody drug conjugate trastuzumab deruxtecan (T-DXd) showed substantial intracranial activity in patients with HER2-positive breast cancer whose disease had metastasised to the brain. The DESTINY-Breast12 study, presented at the Congress of the European Society for Medical Oncology (ESMO), held…