Posts by tag
cancer vaccines
CancerWorld #114 (April 2026)
In oncology, we are trained to deliver hope alongside difficult truths. We speak about survival rates, probabilities, and outcomes. In conflict settings, those terms lose stability. What does survival mean when hospitals are destroyed, treatments cannot reach patients, and people…
Personalised RNA vaccine combined with immune checkpoint inhibitor shows efficacy in melanoma
In advanced melanoma, adding a personalised mRNA-based vaccine to the immune checkpoint inhibitor pembrolizumab improved recurrence-free survival compared with pembrolizumab alone. The KEYNOTE-942 study (presentation number CT001), presented at the AACR (American Association for Cancer Research) Annual Meeting 2023, held…
Cancer and the immune system: turning insights into treatments
The vision of harnessing our immune systems to fight cancer has been tantalising scientists and doctors for more than a century. The idea had a strong scientific rationale: over millions of years our immune systems have evolved intricate and multi-layered…
What can we expect from mRNA cancer vaccines?
Messenger RNA vaccines turned around Europe’s fight against the Covid pandemic. Less than a year after the first lockdowns were declared, mRNA vaccines got regulatory approval for emergency use, first in people at high-risk from Covid, and later in the…
AACR: cancer vaccine combination shows clinical activity in advanced solid tumors
According to an industry-funded, preliminary clinical trial presented at the AACR Virtual Annual Meeting currently underway, a personalized cancer vaccine in combination with the PD-L1 inhibitor atezolizumab appears to be well tolerated and to show modest clinical benefit in patients…