New technologies and innovative approaches can help preventing and overcome innate or acquired resistance to EGFR inhibitors, improving their therapeutic effects Since their first approval and use, more than 15 years ago, inhibitors of the [more]
Day two of ABC-Lisbon featured a pioneer in metastatic breast cancer advocacy, Musa Mayer, who gave the ABC Award lecture. Mayer told the history of how the “silent voices” of women with advanced disease came [more]
Progress in understanding resistance and learning how to combine and sequence therapies most effectively is being stifled because specimens donated by patients, and related data, are being hoarded and not shared. Peter McIntyre reports. There [more]
Recent years have seen a revival of interest in the unique metabolism of cancer cells. This time the focus is on the potential it offers as a target, rather than any possible causal role [more]
Pharmacokinetics within tumour cells play an important role in the development of resistance. A better understanding of the mechanisms involved is important for devising treatment strategies to extend tumour response. We know that cancer cells [more]
Advances in imaging and molecular biology are opening up a wealth of new avenues for research and treatment in radiotherapy. But could progress be held back by a lack of public awareness of the potential [more]
Is there a logic, a pattern, a system behind the way cancer cells adapt to develop resistance to agents designed to kill them? Cancer research is calling on systems biologists to see if they can [more]