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Cancerworld Magazine > brain metastases

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brain metastases

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Radiotherapy prior to immunotherapy is the best treatment sequence for melanoma related brain metastases
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Radiotherapy prior to immunotherapy is the best treatment sequence for melanoma related brain metastases

  • Janet Fricker
  • 6 December 2024

Patients with melanoma related brain metastases achieve reduced risk of progression and better overall survival if they receive radiotherapy before immunotherapy as opposed to the other way round. The meta-analysis study, abstract RADT-04, presented at the Society of Neuro Oncology…

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Antibody-drug conjugate proves effective against active brain metastases
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Antibody-drug conjugate proves effective against active brain metastases

  • Janet Fricker
  • 26 September 2024

The antibody drug conjugate trastuzumab deruxtecan (T-DXd) showed substantial intracranial activity in patients with HER2-positive breast cancer whose disease had metastasised to the brain. The DESTINY-Breast12 study, presented at the Congress of the European Society for Medical Oncology (ESMO), held…

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