translational research

The 2026 Pezcoller Foundation–AACR International Award for Extraordinary Achievement in Cancer Research has recognised two scientists whose discoveries reshaped one of oncology’s greatest ambitions: preventing cancer before it begins. On 9 May, at the Teatro Sociale in Trento, Italy, Dr…

Metastatic pancreatic cancer remains one of the most treatment-refractory solid tumours in oncology. Despite multiple incremental refinements over the past decade, first-line therapy continues to rely on cytotoxic chemotherapy, most commonly FOLFIRINOX or gemcitabine plus nab-paclitaxel, with limited change in…

How policy, philanthropy, and scientific collaboration are reshaping the cancer research landscape and why early detection can be the difference between life and death. Twenty years ago, I received a diagnosis that changed everything and led me to dedicate the…

From genetics to palliative care, clinician-scientist Rita Canário reflects on building a career in Oncology  that bridges research, patient care, and the human side of medicine and why this integration is essential for the future of oncology. “I was never…

Scientific discovery drives oncology forward, but progress only truly begins when knowledge is turned into action. Every issue of CancerWorld explores the people, ideas, and systems shaping the future of oncology. Scientific breakthroughs remain essential, but their true value emerges…

Chimeric antigen receptor natural killer T (CAR-NKT) cell therapy, a novel form of immunotherapy, is emerging as a promising ‘off-the-shelf’ treatment for patients with pancreatic cancer. In a study published in PNAS, November 21, 2025, U.S. investigators report that CAR-NKT cells…