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Cancerworld Magazine > immunotherapy

Posts by tag

immunotherapy

25 posts
Curious, Rejected,Accepted: An ESO Fellow’s Road to Becoming an Oncologist
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Curious, Rejected,Accepted: An ESO Fellow’s Road to Becoming an Oncologist

  • Amalya Sargsyan
  • 3 July 2025

It was 2018, and I was a fifth-year medical student at Yerevan State Medical University. Word spread that our new oncology professor was someone extraordinary: Gevorg Tamamyan - a Harvard-trained, Nature-published pioneer of pediatric oncology in Armenia and president of…

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Microbiota-Derived Bile Acids as Androgen Receptor Antagonists Enhance Anti-Tumour Immunity
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  • News

Microbiota-Derived Bile Acids as Androgen Receptor Antagonists Enhance Anti-Tumour Immunity

  • Janet Fricker
  • 19 June 2025

The gut microbiota can transform cholesterol-derived bile acids into metabolites capable of blocking androgen receptors and strengthening anti-cancer immunity. The study, published in Cell, April 15, demonstrates how one of the microbiota-derived secondary bile acids is capable of suppressing tumour…

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What Caught Our Eye in April: Oncology’s Top Moments
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What Caught Our Eye in April: Oncology’s Top Moments

  • Janet Fricker
  • 7 May 2025

April 2025 marked a significant month in oncology, with notable advancements in cancer treatment and research. Here’s a summary of the most compelling studies and recent breakthroughs that caught our eye this month. Popular CT scans could account for 5%…

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What If the World’s Leading Prostate Cancer Epidemiologist Opened a Restaurant?  A Conversation with Lorelei Mucci- A Harvard Scientist, A Mother, A Leader
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  • Profiles

What If the World’s Leading Prostate Cancer Epidemiologist Opened a Restaurant? A Conversation with Lorelei Mucci- A Harvard Scientist, A Mother, A Leader

  • Gevorg Tamamyan
  • 23 April 2025

I always close my interviews with a signature question: "Who should I speak with next?"It’s a small but revealing moment — a window into whom the giants of oncology admire, learn from, and find truly compelling. When I posed the…

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Could this dual approach be the frontier that finally gets immunotherapy to work for MSS colorectal cancer?
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  • Medicine

Could this dual approach be the frontier that finally gets immunotherapy to work for MSS colorectal cancer?

  • Amalya Sargsyan
  • 31 March 2025

It is often said in medicine that the only true constant in facing life-threatening diseases is change. Nowhere is this more evident than in oncology, where advances in chemotherapy, targeted therapies, immunotherapies, and other novel agents continue to spark hope.…

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Radiotherapy prior to immunotherapy is the best treatment sequence for melanoma related brain metastases
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Radiotherapy prior to immunotherapy is the best treatment sequence for melanoma related brain metastases

  • Janet Fricker
  • 6 December 2024

Patients with melanoma related brain metastases achieve reduced risk of progression and better overall survival if they receive radiotherapy before immunotherapy as opposed to the other way round. The meta-analysis study, abstract RADT-04, presented at the Society of Neuro Oncology…

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Study helps solve the puzzle of checkpoint inhibitor myocarditis
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Study helps solve the puzzle of checkpoint inhibitor myocarditis

  • Janet Fricker
  • 22 November 2024

The immune reaction that occurs in the hearts of patients taking checkpoint inhibitors who develop immune checkpoint myocarditis may be distinct from the immune responses occurring in the tumours of these patients. The study, published in in Nature, 6 November,…

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Rise in initiation of immunotherapy at the end of life
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Rise in initiation of immunotherapy at the end of life

  • Janet Fricker
  • 26 January 2024

Immunotherapy is increasingly being initiated in the month prior to death in patients with stage IV non-small-cell lung cancer, melanoma, and renal cell carcinoma. The US study, published in JAMA Oncology, online January 4, showed the practice was more common…

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Combination immunotherapy with novel immune-oncology agents benefit NSCLC patients in presurgical setting
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Combination immunotherapy with novel immune-oncology agents benefit NSCLC patients in presurgical setting

  • Janet Fricker
  • 6 October 2023

Patients with resectable non-small-cell lung cancer show improved major pathological response rates with combination immune oncology agents versus single-agent immunotherapy. The NeoCOAST trial, published in Cancer Discovery, 14 September, demonstrated that combining the anti-PD-L1 monoclonal antibody durvalumab with other novel…

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Cracking RAS: It took over 30 years to hit this ubiquitous oncogene – was it worth the wait?
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  • Articles
  • Biology basic

Cracking RAS: It took over 30 years to hit this ubiquitous oncogene – was it worth the wait?

  • Lisa Hutchinson
  • 14 June 2023

RAS oncogenes and their proteins have central roles in almost all cancers, including leukaemias, multiple myelomas, skin cancers and many solid tumours, making the RAS protein family an ideal cancer target. But efforts to develop clinically efficacious drugs to target…

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  • How a Brain-Destroying Protein Became Cancer’s Ally: Alpha-Synuclein Emerges as a New Target in Melanoma
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  • How a Chicken Egg Model Could Transform Pediatric Cancer Treatment in Canada
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Contents
  • Suheir Rasul: Protecting Human Dignity
    • 4 July 2025
  • Equity:The Word That Shaped Her Career From The Lab To The White House:The Story Of Catharine Young
    • 4 July 2025
  • Curious, Rejected,Accepted: An ESO Fellow’s Road to Becoming an Oncologist
    • 3 July 2025
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